{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T14:44:24Z","timestamp":1793371464600,"version":"4.5.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006190","name":"VA ORD","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contemporary Clinical Trials"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.cct.2024.107569","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T02:14:34Z","timestamp":1715220874000},"page":"107569","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Ketamine-enhanced prolonged exposure therapy in veterans with PTSD: A randomized controlled trial protocol"],"prefix":"10.1016","volume":"143","author":[{"given":"Paulo R.","family":"Shiroma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Thuras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa A.","family":"Polusny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Kehle-Forbes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth","family":"Disner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose V.","family":"Pardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey","family":"Gilmore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Tolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Voller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"McManus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christie","family":"King","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Lipinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Eng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine","family":"Hawkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.cct.2024.107569_bb0005","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.cpr.2010.04.007","article-title":"A meta-analytic review of prolonged exposure for posttraumatic stress disorder","volume":"30","author":"Powers","year":"2010","journal-title":"Clin. Psychol. Rev."},{"issue":"8","key":"10.1016\/j.cct.2024.107569_bb0010","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1001\/jama.297.8.820","article-title":"Cognitive behavioral therapy for posttraumatic stress disorder in women: a randomized controlled trial","volume":"297","author":"Schnurr","year":"2007","journal-title":"Jama"},{"issue":"5","key":"10.1016\/j.cct.2024.107569_bb0015","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1001\/jama.2015.8370","article-title":"Psychotherapy for military-related PTSD: a review of randomized clinical trials","volume":"314","author":"Steenkamp","year":"2015","journal-title":"Jama"},{"key":"10.1016\/j.cct.2024.107569_bb0020","author":"Defense. USDoVAUSDo"},{"issue":"2","key":"10.1016\/j.cct.2024.107569_bb0025","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.pnpbp.2008.12.004","article-title":"Pharmacologic alternatives to antidepressants in posttraumatic stress disorder: a systematic review","volume":"33","author":"Berger","year":"2009","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.cct.2024.107569_bb0030","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.brat.2012.11.004","article-title":"Pre-trauma individual differences in extinction learning predict posttraumatic stress","volume":"51","author":"Lommen","year":"2013","journal-title":"Behav. Res. Ther."},{"issue":"6911","key":"10.1016\/j.cct.2024.107569_bb0035","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nature01138","article-title":"Neurons in medial prefrontal cortex signal memory for fear extinction","volume":"420","author":"Milad","year":"2002","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.cct.2024.107569_bb0040","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.biopsych.2006.10.011","article-title":"Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert","volume":"62","author":"Milad","year":"2007","journal-title":"Biol. Psychiatry"},{"issue":"11","key":"10.1016\/j.cct.2024.107569_bb0045","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/nrn3339","article-title":"Biological studies of post-traumatic stress disorder","volume":"13","author":"Pitman","year":"2012","journal-title":"Nat. Rev. Neurosci."},{"issue":"35","key":"10.1016\/j.cct.2024.107569_bb0050","doi-asserted-by":"crossref","first-page":"5645","DOI":"10.2174\/138161212803530899","article-title":"Pharmacological innovations for posttraumatic stress disorder and medication- enhanced psychotherapy","volume":"18","author":"Dunlop","year":"2012","journal-title":"Curr. Pharm. Des."},{"issue":"1","key":"10.1016\/j.cct.2024.107569_bb0055","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1177\/0269881112456611","article-title":"Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3,4-methylenedioxymethamphetamine-assisted psychotherapy: a prospective long-term follow-up study","volume":"27","author":"Mithoefer","year":"2013","journal-title":"J. Psychopharmacol."},{"issue":"5","key":"10.1016\/j.cct.2024.107569_bb0060","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1001\/jamapsychiatry.2016.3955","article-title":"D-cycloserine augmentation of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders: a systematic review and meta-analysis of individual participant data","volume":"74","author":"Mataix-Cols","year":"2017","journal-title":"JAMA Psychiatry"},{"issue":"8","key":"10.1016\/j.cct.2024.107569_bb0065","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.biopsych.2010.12.015","article-title":"Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure","volume":"69","author":"Li","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.cct.2024.107569_bb0070","first-page":"1","article-title":"Ketamine accelerates fear extinction via mTORC1 signaling","volume":"100","author":"Girgenti","year":"2017","journal-title":"Apr"},{"issue":"3","key":"10.1016\/j.cct.2024.107569_bb0075","doi-asserted-by":"crossref","first-page":"408","DOI":"10.4088\/JCP.15l10138","article-title":"Can exposure-based CBT extend the effects of intravenous ketamine in obsessive-compulsive disorder? An open-label trial","volume":"77","author":"Rodriguez","year":"2016","journal-title":"J. Clin. Psychiatry"},{"issue":"6","key":"10.1016\/j.cct.2024.107569_bb0080","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.20l13406","article-title":"A proof-of-concept study of subanesthetic intravenous ketamine combined with prolonged exposure therapy among veterans with post-traumatic stress disorder","volume":"81","author":"Shiroma","year":"2020","journal-title":"J. Clin. Psychiatry"},{"issue":"5","key":"10.1016\/j.cct.2024.107569_bb0085","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1159\/000507095","article-title":"Continuous ketamine infusion for pain as an opportunity for psychotherapy for PTSD: a case series of ketamine-enhanced psychotherapy for PTSD and pain (KEP-P2)","volume":"89","author":"Keizer","year":"2020","journal-title":"Psychother. Psychosom."},{"issue":"11","key":"10.1016\/j.cct.2024.107569_bb0090","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1038\/s41386-023-01606-3","article-title":"Long term structural and functional neural changes following a single infusion of ketamine in PTSD","volume":"48","author":"Duek","year":"2023","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.cct.2024.107569_bb0095","doi-asserted-by":"crossref","unstructured":"Kanto JH. Midazolam: the first water-soluble benzodiazepine. Pharmacology, pharmacokinetics and efficacy in insomnia and anesthesia. Pharmacotherapy May-Jun 1985;5(3):138\u201355. doi:https:\/\/doi.org\/10.1002\/j.1875-9114.1985.tb03411.x.","DOI":"10.1002\/j.1875-9114.1985.tb03411.x"},{"issue":"2","key":"10.1016\/j.cct.2024.107569_bb0100","first-page":"91","article-title":"Combined pharmacotherapy and cognitive-behavioral therapy for anxiety disorders: medication effects, glucocorticoids, and attenuated treatment outcomes","volume":"17","author":"Otto","year":"2010","journal-title":"Clin Psychol (New York)"},{"key":"10.1016\/j.cct.2024.107569_bb0105","series-title":"Scale available from the national center for PTSD. The PTSD checklist for DSM-5 (PCL-5)","author":"Weathers","year":"2013"},{"key":"10.1016\/j.cct.2024.107569_bb0110","series-title":"The Life Events Checklist for DSM-5 (LEC-5)","author":"Weathers","year":"2013"},{"issue":"6","key":"10.1016\/j.cct.2024.107569_bb0115","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1002\/jts.21868","article-title":"Deployment risk and resilience inventory-2 (DRRI-2): an updated tool for assessing psychosocial risk and resilience factors among service members and veterans","volume":"26","author":"Vogt","year":"2013","journal-title":"J. Trauma. Stress."},{"issue":"3","key":"10.1016\/j.cct.2024.107569_bb0120","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1037\/pas0000486","article-title":"The clinician-administered PTSD scale for DSM-5 (CAPS-5): development and initial psychometric evaluation in military veterans","volume":"30","author":"Weathers","year":"2018","journal-title":"Psychol. Assess."},{"issue":"Suppl. 20","key":"10.1016\/j.cct.2024.107569_bb0125","first-page":"22","article-title":"The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"J. Clin. Psychiatry"},{"issue":"3","key":"10.1016\/j.cct.2024.107569_bb0130","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"issue":"6","key":"10.1016\/j.cct.2024.107569_bb0135","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/01.HTR.0000300233.98242.87","article-title":"Screening for traumatic brain injury in troops returning from deployment in Afghanistan and Iraq: initial investigation of the usefulness of a short screening tool for traumatic brain injury","volume":"22","author":"Schwab","year":"2007","journal-title":"J. Head Trauma Rehabil."},{"issue":"6","key":"10.1016\/j.cct.2024.107569_bb0140","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1360-0443.1993.tb02093.x","article-title":"Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption--II","volume":"88","author":"Saunders","year":"1993","journal-title":"Addiction"},{"issue":"7","key":"10.1016\/j.cct.2024.107569_bb0145","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.acn.2006.05.007","article-title":"Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs","volume":"21","author":"Gualtieri","year":"2006","journal-title":"Arch. Clin. Neuropsychol."},{"issue":"3","key":"10.1016\/j.cct.2024.107569_bb0150","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1097\/00006842-197905000-00004","article-title":"Impact of event scale: a measure of subjective stress","volume":"41","author":"Horowitz","year":"1979","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.cct.2024.107569_bb0155","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A new depression scale designed to be sensitive to change","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br. J. Psychiatry J. Mental Sci."},{"issue":"6","key":"10.1016\/j.cct.2024.107569_bb0160","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1037\/0022-006X.56.6.893","article-title":"An inventory for measuring clinical anxiety: psychometric properties","volume":"56","author":"Beck","year":"1988","journal-title":"J. Consult. Clin. Psychol."},{"issue":"12","key":"10.1016\/j.cct.2024.107569_bb0165","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1176\/appi.ajp.2011.10111704","article-title":"The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults","volume":"168","author":"Posner","year":"2011","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.cct.2024.107569_bb0170","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0304-3959(01)00349-9","article-title":"Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale","volume":"94","author":"Farrar","year":"2001","journal-title":"Pain"},{"issue":"7","key":"10.1016\/j.cct.2024.107569_bb0175","first-page":"28","article-title":"The clinical global impressions scale: applying a research tool in clinical practice","volume":"4","author":"Busner","year":"2007","journal-title":"Psychiatry (Edgmont)"},{"issue":"2","key":"10.1016\/j.cct.2024.107569_bb0180","first-page":"299","article-title":"The World Health Organization\u2019s WHOQOL-BREF quality of life assessment: psychometric properties and results of the international field trial. A report from the WHOQOL group","volume":"13","author":"Skevington","year":"2004","journal-title":"Qual. Life Res. Int. J. Qual. Life Asp. Treat. Care Rehab."},{"issue":"2","key":"10.1016\/j.cct.2024.107569_bb0185","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0005-7916(00)00012-4","article-title":"Psychometric properties of the credibility\/expectancy questionnaire","volume":"31","author":"Devilly","year":"2000","journal-title":"J. Behav. Ther. Exp. Psychiatry"},{"issue":"1","key":"10.1016\/j.cct.2024.107569_bb0190","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1176\/appi.ajp.163.1.28","article-title":"Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice","volume":"163","author":"Trivedi","year":"2006","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.cct.2024.107569_bb0195","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00131746-200603000-00002","article-title":"Self-rated global measure of the frequency, intensity, and burden of side effects","volume":"12","author":"Wisniewski","year":"2006","journal-title":"J. Psychiatr. Pract."},{"issue":"3","key":"10.1016\/j.cct.2024.107569_bb0200","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/cpp.658","article-title":"Working Alliance inventory-short revised (WAI-SR): psychometric properties in outpatients and inpatients","volume":"17","author":"Munder","year":"2010","journal-title":"Clin Psychol Psychother"},{"key":"10.1016\/j.cct.2024.107569_bb0205","series-title":"Behavior Therapy Techniques","author":"La","year":"1966"},{"key":"10.1016\/j.cct.2024.107569_bb0210","doi-asserted-by":"crossref","first-page":"799","DOI":"10.2466\/pr0.1962.10.3.799","article-title":"The brief psychiatric rating scale","volume":"10","author":"Overall JEGDR","year":"1962","journal-title":"Psychol. Rep."},{"issue":"1","key":"10.1016\/j.cct.2024.107569_bb0215","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1023\/A:1024465317902","article-title":"Measurement of dissociative states with the clinician-administered dissociative states scale (CADSS)","volume":"11","author":"Bremner","year":"1998","journal-title":"J. Trauma. Stress."},{"key":"10.1016\/j.cct.2024.107569_bb0220","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: reliability, validity and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"Br. J. Psychiatry J. Mental Sci."},{"issue":"1","key":"10.1016\/j.cct.2024.107569_bb0225","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0952-8180(94)00001-K","article-title":"The post-anesthesia recovery score revisited","volume":"7","author":"Aldrete","year":"1995","journal-title":"J. Clin. Anesth."},{"key":"10.1016\/j.cct.2024.107569_bb0230","series-title":"Prolonged Exposure Therapy for PTSD: Emotional Processing of Traumatic Experiences","author":"E.B. Foa EAH","year":"2007"},{"key":"10.1016\/j.cct.2024.107569_bb0235","doi-asserted-by":"crossref","DOI":"10.1176\/appi.ajp.2020.20050596","article-title":"A randomized controlled trial of repeated ketamine administration for chronic posttraumatic stress disorder","author":"Feder","year":"2021","journal-title":"Am. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.cct.2024.107569_bb0240","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.cbpra.2010.10.002","article-title":"Treatment of PTSD in older adults: Do cognitive-behavioral interventions remain viable?","volume":"19","author":"Clapp","year":"2012","journal-title":"Cogn. Behav. Pract."},{"issue":"2","key":"10.1016\/j.cct.2024.107569_bb0245","doi-asserted-by":"crossref","first-page":"141","DOI":"10.31887\/DCNS.2015.17.2\/jflory","article-title":"Comorbidity between post-traumatic stress disorder and major depressive disorder: alternative explanations and treatment considerations","volume":"17","author":"Flory","year":"2015","journal-title":"Dialogues Clin. Neurosci."},{"issue":"25","key":"10.1016\/j.cct.2024.107569_bb0250","doi-asserted-by":"crossref","first-page":"5704","DOI":"10.1523\/JNEUROSCI.0786-04.2004","article-title":"Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex","volume":"24","author":"Santini","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cct.2024.107569_bb0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.nbd.2016.12.026","article-title":"Ketamine accelerates fear extinction via mTORC1 signaling","volume":"100","author":"Girgenti","year":"2017","journal-title":"Neurobiol. Dis."},{"issue":"3","key":"10.1016\/j.cct.2024.107569_bb0260","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1038\/mp.2016.249","article-title":"Ketamine: translating mechanistic discoveries into the next generation of glutamate modulators for mood disorders","volume":"22","author":"Zarate","year":"2017","journal-title":"Mol. Psychiatry"},{"issue":"1","key":"10.1016\/j.cct.2024.107569_bb0265","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/npp.2010.88","article-title":"Glutamate receptors in extinction and extinction-based therapies for psychiatric illness","volume":"36","author":"Myers","year":"2011","journal-title":"Neuropsychopharmacology"},{"issue":"26","key":"10.1016\/j.cct.2024.107569_bb0270","doi-asserted-by":"crossref","first-page":"8106","DOI":"10.1073\/pnas.1414728112","article-title":"Optogenetic stimulation of infralimbic PFC reproduces ketamine\u2019s rapid and sustained antidepressant actions","volume":"112","author":"Fuchikami","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"12","key":"10.1016\/j.cct.2024.107569_bb0275","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1001\/archpsyc.1995.03950240066012","article-title":"Posttraumatic stress disorder in the National Comorbidity Survey","volume":"52","author":"Kessler","year":"1995","journal-title":"Arch. Gen. Psychiatry"},{"issue":"1","key":"10.1016\/j.cct.2024.107569_bb0280","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1023\/A:1014379127240","article-title":"Comorbid anxiety disorders in civilians seeking treatment for posttraumatic stress disorder","volume":"15","author":"Zayfert","year":"2002","journal-title":"J. Trauma. Stress."},{"issue":"3","key":"10.1016\/j.cct.2024.107569_bb0285","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/jts.21814","article-title":"The co-occurrence of major depressive disorder among individuals with posttraumatic stress disorder: a meta-analysis","volume":"26","author":"Rytwinski","year":"2013","journal-title":"J. Trauma. Stress."},{"issue":"4","key":"10.1016\/j.cct.2024.107569_bb0290","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1037\/0022-006X.70.4.1022","article-title":"Does imaginal exposure exacerbate PTSD symptoms?","volume":"70","author":"Foa","year":"2002","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.cct.2024.107569_bb0295","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.brat.2015.12.009","article-title":"Symptom exacerbations in trauma-focused treatments: associations with treatment outcome and non-completion","volume":"77","author":"Larsen","year":"2016","journal-title":"Behav. Res. Ther."},{"issue":"1","key":"10.1016\/j.cct.2024.107569_bb0300","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1037\/a0035286","article-title":"Depression sudden gains and transient depression spikes during treatment for PTSD","volume":"82","author":"Keller","year":"2014","journal-title":"J. Consult. Clin. Psychol."}],"container-title":["Contemporary Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714424001526?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714424001526?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T01:24:22Z","timestamp":1722302662000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551714424001526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":60,"alternative-id":["S1551714424001526"],"URL":"https:\/\/doi.org\/10.1016\/j.cct.2024.107569","relation":{},"ISSN":["1551-7144"],"issn-type":[{"value":"1551-7144","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ketamine-enhanced prolonged exposure therapy in veterans with PTSD: A randomized controlled trial protocol","name":"articletitle","label":"Article Title"},{"value":"Contemporary Clinical Trials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cct.2024.107569","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"107569"}}