{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:41:52Z","timestamp":1757706112111,"version":"3.37.3"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000890","name":"National Multiple Sclerosis Society","doi-asserted-by":"publisher","award":["RFA-2301-40758"],"award-info":[{"award-number":["RFA-2301-40758"]}],"id":[{"id":"10.13039\/100000890","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contemporary Clinical Trials"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.cct.2024.107630","type":"journal-article","created":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T16:19:35Z","timestamp":1720887575000},"page":"107630","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Rationale and methodology for examining the combination of aerobic exercise and cognitive rehabilitation on new learning and memory in persons with multiple sclerosis and mobility disability: Protocol for a randomized controlled trial"],"prefix":"10.1016","volume":"144","author":[{"given":"Carly L.A.","family":"Wender","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odalys","family":"Arbelaez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tien T.","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amber","family":"Salter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn R.","family":"Wylie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert W.","family":"Motl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian M.","family":"Sandroff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy D.","family":"Chiaravalloti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cct.2024.107630_bb0005","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev.neuro.30.051606.094313","article-title":"Multiple sclerosis: an immune or neurodegenerative disorder?","volume":"31","author":"Trapp","year":"2008","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.cct.2024.107630_bb0010","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1177\/135245850000600207","article-title":"Cost and health related quality of life consequences of multiple sclerosis","volume":"6","author":"Grima","year":"2000","journal-title":"Mult. Scler."},{"key":"10.1016\/j.cct.2024.107630_bb0015","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1002\/ana.24769","article-title":"Preclinical disease activity in multiple sclerosis: a prospective study of cognitive performance prior to first symptom","volume":"80","author":"Cortese","year":"2016","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.cct.2024.107630_bb0020","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2019.00261","article-title":"Cognitive impairment in multiple sclerosis with regards to disease duration and clinical phenotypes","volume":"10","author":"Brochet","year":"2019","journal-title":"Front. Neurol."},{"key":"10.1016\/j.cct.2024.107630_bb0025","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/01688639408402629","article-title":"The nature of memory impairments in multiple sclerosis: acquisition versus retrieval","volume":"16","author":"DeLuca","year":"1994","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"10.1016\/j.cct.2024.107630_bb0030","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1017\/S1355617706060723","article-title":"Validity of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS)","volume":"12","author":"Benedict","year":"2006","journal-title":"J. Int. Neuropsychol. Soc."},{"key":"10.1016\/j.cct.2024.107630_bb0035","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.apmr.2009.09.022","article-title":"Actual reality: a new approach to functional assessment in persons with multiple sclerosis","volume":"91","author":"Goverover","year":"2010","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"10.1016\/j.cct.2024.107630_bb0040","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/s41582-020-0355-1","article-title":"Treatment and management of cognitive dysfunction in patients with multiple sclerosis","volume":"16","author":"DeLuca","year":"2020","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.cct.2024.107630_bb0045","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1017\/S1355617711000403","article-title":"Upper and lower extremity motor function and cognitive impairment in multiple sclerosis","volume":"17","author":"Benedict","year":"2011","journal-title":"J. Int. Neuropsychol. Soc."},{"key":"10.1016\/j.cct.2024.107630_bb0050","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1177\/1352458520914822","article-title":"Do subcortical gray matter volumes and aerobic capacity account for cognitive-motor coupling in multiple sclerosis?","volume":"27","author":"Motl","year":"2021","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.cct.2024.107630_bb0055","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1177\/1352458514567727","article-title":"Memory impairment in multiple sclerosis: relevance of hippocampal activation and hippocampal connectivity","volume":"21","author":"Hulst","year":"2015","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.cct.2024.107630_bb0060","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s40263-020-00734-4","article-title":"Cognitive efficacy of pharmacologic treatments in multiple sclerosis: a systematic review","volume":"34","author":"Chen","year":"2020","journal-title":"CNS Drugs"},{"key":"10.1016\/j.cct.2024.107630_bb0065","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.apmr.2017.07.021","article-title":"Evidenced-based cognitive rehabilitation for persons with multiple sclerosis: an updated review of the literature from 2007 to 2016","volume":"99","author":"Goverover","year":"2018","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"10.1016\/j.cct.2024.107630_bb0070","first-page":"1","article-title":"The hippocampus and spatial constraints on mental imagery","volume":"0","author":"Bird","year":"2012","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.cct.2024.107630_bb0075","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/1098-1063(2000)10:4<389::AID-HIPO5>3.0.CO;2-P","article-title":"Computational principles of learning in the neocortex and hippocampus","volume":"10","author":"O\u2019Reilly","year":"2000","journal-title":"Hippocampus"},{"key":"10.1016\/j.cct.2024.107630_bb0080","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1212\/01.wnl.0000437295.97946.a8","article-title":"An RCT to treat learning impairment in multiple sclerosis: the MEMREHAB trial","volume":"81","author":"Chiaravalloti","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.cct.2024.107630_bb0085","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1177\/1352458519826463","article-title":"The efficacy of the modified story memory technique in progressive MS","volume":"26","author":"Chiaravalloti","year":"2020","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.cct.2024.107630_bb0090","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s11682-014-9309-9","article-title":"A pilot study examining functional brain activity 6 months after memory retraining in MS: the MEMREHAB trial","volume":"8","author":"Dobryakova","year":"2014","journal-title":"Brain Imaging Behav."},{"key":"10.1016\/j.cct.2024.107630_bb0095","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1007\/s00415-011-6353-x","article-title":"Increased cerebral activation after behavioral treatment for memory deficits in MS","volume":"259","author":"Chiaravalloti","year":"2012","journal-title":"J. Neurol."},{"key":"10.1016\/j.cct.2024.107630_bb0100","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1016\/S0140-6736(99)90035-1","article-title":"Rehabilitation still the only way to improve function in multiple sclerosis","volume":"354","author":"Kraft","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.cct.2024.107630_bb0105","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1073\/pnas.1015950108","article-title":"Exercise training increases size of hippocampus and improves memory","volume":"108","author":"Erickson","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cct.2024.107630_bb0110","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1136\/bjsports-2013-093184","article-title":"Aerobic exercise increases hippocampal volume in older women with probable mild cognitive impairment: a 6-month randomised controlled trial","volume":"49","author":"ten Brinke","year":"2015","journal-title":"Br. J. Sports Med."},{"key":"10.1016\/j.cct.2024.107630_bb0115","doi-asserted-by":"crossref","first-page":"E129","DOI":"10.1519\/JPT.0000000000000172","article-title":"Aerobic exercise sustains performance of instrumental activities of daily living in early-stage Alzheimer disease","volume":"42","author":"Vidoni","year":"2019","journal-title":"J. Geriatr. Phys. Ther."},{"key":"10.1016\/j.cct.2024.107630_bb0120","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1080\/13554794.2013.841951","article-title":"Aerobic exercise increases hippocampal volume and improves memory in multiple sclerosis: preliminary findings","volume":"20","author":"Leavitt","year":"2014","journal-title":"Neurocase"},{"key":"10.1016\/j.cct.2024.107630_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.cct.2021.106563","article-title":"Effects of walking exercise training on learning and memory and hippocampal neuroimaging outcomes in MS: a targeted, pilot randomized controlled trial","volume":"110","author":"Sandroff","year":"2021","journal-title":"Contemp. Clin. Trials"},{"key":"10.1016\/j.cct.2024.107630_bb0130","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1177\/1352458513507358","article-title":"Effects of exercise on fitness and cognition in progressive MS: a randomized, controlled pilot trial","volume":"20","author":"Briken","year":"2014","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.cct.2024.107630_bb0135","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1177\/1545968318798938","article-title":"Integrative CNS plasticity with exercise in MS: the PRIMERS (PRocessing, integration of multisensory exercise-related stimuli) conceptual framework","volume":"32","author":"Sandroff","year":"2018","journal-title":"Neurorehabil. Neural Repair"},{"issue":"18","key":"10.1016\/j.cct.2024.107630_bb0140","doi-asserted-by":"crossref","first-page":"8283","DOI":"10.3390\/ijerph18168283","article-title":"Moderate exercise combined with enriched environment enhances learning and memory through BDNF\/TrkB signaling pathway in rats","volume":"2021","author":"Xu","year":"2021","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.cct.2024.107630_bb0145","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1586\/ern.10.201","article-title":"Can virtual reality offer enriched environments for rehabilitation?","volume":"11","author":"Levin","year":"2011","journal-title":"Expert. Rev. Neurother."},{"key":"10.1016\/j.cct.2024.107630_bb0150","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3390\/neurosci3020015","article-title":"Developing the rationale for including virtual reality in cognitive rehabilitation and exercise training approaches for managing cognitive dysfunction in MS","volume":"3","author":"Wender","year":"2022","journal-title":"NeuroSci"},{"key":"10.1016\/j.cct.2024.107630_bb0155","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1001\/jamaneurol.2023.1135","article-title":"Population-based estimates for the prevalence of multiple sclerosis in the United States by race, ethnicity, age, sex, and geographic region","volume":"80","author":"Hittle","year":"2023","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.cct.2024.107630_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2023.104709","article-title":"Feasibility of remotely delivered and supported aerobic walking exercise training for cognitive processing speed impairment in fully-ambulatory persons with multiple sclerosis","volume":"74","author":"Sandroff","year":"2023","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.cct.2024.107630_bb0165","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/13854040802121158","article-title":"The open-trial selective reminding test (OT-SRT) as a tool for the assessment of learning and memory","volume":"23","author":"Chiaravalloti","year":"2009","journal-title":"Clin. Neuropsychol."},{"key":"10.1016\/j.cct.2024.107630_bb0170","doi-asserted-by":"crossref","first-page":"3303","DOI":"10.1007\/s40520-021-01886-z","article-title":"Norms and equivalences for MoCA-30, MoCA-22, and MMSE in the oldest-old","volume":"33","author":"Melikyan","year":"2021","journal-title":"Aging Clin. Exp. Res."},{"key":"10.1016\/j.cct.2024.107630_bb0175","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/gps.830","article-title":"Utility of TICS-M for the assessment of cognitive function in older adults","volume":"18","author":"De Jager","year":"2003","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.cct.2024.107630_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2020.102169","article-title":"Adherence and drop-out in randomized controlled trials of exercise interventions in people with multiple sclerosis: a systematic review and meta-analyses","volume":"43","author":"Dennett","year":"2020","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.cct.2024.107630_bb0185","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jns.2014.05.016","article-title":"The safety of exercise training in multiple sclerosis: a systematic review","volume":"343","author":"Pilutti","year":"2014","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.cct.2024.107630_bb0190","doi-asserted-by":"crossref","DOI":"10.1177\/13524585241229332","article-title":"Drop-out, adherence, and compliance in randomized controlled trials of exercise training in multiple sclerosis: short report","author":"Motl","year":"2024","journal-title":"Mult. Scler. J."},{"year":"2000","series-title":"CVLT-II: California Verbal Learning Test 2nd Edition; Adult Version, 2nd Editio","author":"Delis","key":"10.1016\/j.cct.2024.107630_bb0195"},{"key":"10.1016\/j.cct.2024.107630_bb0200","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/arclin\/6.3.234a","article-title":"The memory assessment scales (MAS): a new clinical memory battery","volume":"6","author":"Williams","year":"1991","journal-title":"Arch. Clin. Neuropsychol."},{"year":"1995","series-title":"The Brief Visuospatial Memory Test Revised (BVMT-R): Manual","author":"Benedict","key":"10.1016\/j.cct.2024.107630_bb0205"},{"key":"10.1016\/j.cct.2024.107630_bb0210","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3109\/02699052.2010.541894","article-title":"Ecologically-oriented neurorehabilitation of memory: robustness of outcome across diagnosis and severity","volume":"25","author":"Stringer","year":"2011","journal-title":"Brain Inj."},{"key":"10.1016\/j.cct.2024.107630_bb0215","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/HTR.0000000000000164","article-title":"Examining the efficacy of the modified story memory technique (mSMT) in persons with TBI using functional magnetic resonance imaging (fMRI): the TBI-MEM trial","volume":"30","author":"Chiaravalloti","year":"2015","journal-title":"J. Head Trauma Rehabil."},{"key":"10.1016\/j.cct.2024.107630_bb0220","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.ijpsycho.2019.09.008","article-title":"Brain activation patterns associated with paragraph learning in persons with multiple sclerosis: the MEMREHAB trial","volume":"154","author":"Boukrina","year":"2020","journal-title":"Int. J. Psychophysiol."},{"key":"10.1016\/j.cct.2024.107630_bb0225","doi-asserted-by":"crossref","first-page":"7774","DOI":"10.1016\/j.neuroimage.2012.01.021","article-title":"FreeSurfer","volume":"62","author":"Fischl","year":"2012","journal-title":"Neuroimage"},{"issue":"2014","key":"10.1016\/j.cct.2024.107630_bb0230","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.neuroimage.2013.08.048","article-title":"Methods to detect, characterize, and remove motion artifact in resting state fMRI","volume":"84","author":"Power","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.cct.2024.107630_bb0235","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1002\/hbm.24017","article-title":"A comparison of manual tracing and FreeSurfer for estimating hippocampal volume over the adult lifespan","volume":"39","author":"Schmidt","year":"2018","journal-title":"Hum. Brain Mapp."},{"year":"2004","series-title":"Delis-Kaplan Executive Function System","author":"Baron","key":"10.1016\/j.cct.2024.107630_bb0240"},{"key":"10.1016\/j.cct.2024.107630_bb0245","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.1467-9280.1991.tb00127.x","article-title":"Mediation of adult age differences in cognition by reductions in working memory and speed of processing","volume":"2","author":"Salthouse","year":"1991","journal-title":"Psychol. Sci."},{"key":"10.1016\/j.cct.2024.107630_bb0250","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1212\/WNL.60.1.31","article-title":"Measuring the impact of MS on walking ability: the 12-item MS walking scale (MSWS-12)","volume":"60","author":"Hobart","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.cct.2024.107630_bb0255","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1093\/brain\/124.5.962","article-title":"The multiple sclerosis impact scale (MSIS-29) a new patient-based outcome measure","volume":"124","author":"Hobart","year":"2001","journal-title":"Brain"},{"key":"10.1016\/j.cct.2024.107630_bb0260","series-title":"The Use of Psychological Testing for Treatment Planning and Outcomes Assessment","first-page":"1227","article-title":"SF-36 health survey","author":"Jr Ware","year":"1999"},{"key":"10.1016\/j.cct.2024.107630_bb0265","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jns.2013.05.023","article-title":"Psychometric properties of the fatigue severity scale and the modified fatigue impact scale","volume":"331","author":"Learmonth","year":"2013","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.cct.2024.107630_bb0270","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/00000542-200507000-00028","article-title":"The McGill pain questionnaire: from description to measurement","volume":"103","author":"Melzack","year":"2005","journal-title":"Anesthesiology"},{"key":"10.1016\/j.cct.2024.107630_bb0275","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.cct.2024.107630_bb0280","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1191\/1352458503ms870oa","article-title":"Development and validation of a self-efficacy measure for people with multiple sclerosis: the multiple sclerosis self-efficacy scale","volume":"9","author":"Rigby","year":"2003","journal-title":"Mult. Scler."},{"key":"10.1016\/j.cct.2024.107630_bb0285","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/00006199-200005000-00007","article-title":"Testing the reliability and validity of the self-efficacy for exercise scale","volume":"49","author":"Resnick","year":"2000","journal-title":"Nurs. Res."},{"key":"10.1016\/j.cct.2024.107630_bb0290","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1097\/HTR.0b013e31829af969","article-title":"Participation assessment with recombined tools-objective (PART-O)","volume":"28","author":"Bogner","year":"2013","journal-title":"J. Head Trauma Rehabil."},{"key":"10.1016\/j.cct.2024.107630_bb0295","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1007\/s40279-016-0472-6","article-title":"Comprehensive profile of cardiopulmonary exercise testing in ambulatory persons with multiple sclerosis","volume":"46","author":"Klaren","year":"2016","journal-title":"Sports Med."},{"year":"2020","series-title":"ACSM\u2019s Guidelines for Exercise Testing and Prescription, Eleventh Edition","author":"American College of Sports Medicine","key":"10.1016\/j.cct.2024.107630_bb0300"},{"key":"10.1016\/j.cct.2024.107630_bb0305","series-title":"Human Kinetics","article-title":"Borg\u2019s perceived exertion and pain scales","author":"Borg","year":"2001"},{"key":"10.1016\/j.cct.2024.107630_bb0310","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jns.2014.04.028","article-title":"Validity and reliability of VO2-max measurements in persons with multiple sclerosis","volume":"342","author":"Langeskov-Christensen","year":"2014","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.cct.2024.107630_bb0315","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s40279-015-0307-x","article-title":"Aerobic capacity in persons with multiple sclerosis: a systematic review and meta-analysis","volume":"45","author":"Langeskov-Christensen","year":"2015","journal-title":"Sports Med."},{"key":"10.1016\/j.cct.2024.107630_bb0320","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1177\/13524585211048397","article-title":"Cardiorespiratory fitness and free-living physical activity are not associated with cognition in persons with progressive multiple sclerosis: baseline analyses from the CogEx study","volume":"28","author":"Sandroff","year":"2022","journal-title":"Mult. Scler."},{"key":"10.1016\/j.cct.2024.107630_bb0325","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.cct.2017.07.016","article-title":"Multimodal exercise training in multiple sclerosis: a randomized controlled trial in persons with substantial mobility disability","volume":"61","author":"Sandroff","year":"2017","journal-title":"Contemp. Clin. Trials"},{"key":"10.1016\/j.cct.2024.107630_bb0330","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s11682-012-9183-2","article-title":"Increased functional connectivity within memory networks following memory rehabilitation in multiple sclerosis","volume":"8","author":"Leavitt","year":"2014","journal-title":"Brain Imaging Behav."},{"year":"2013","series-title":"ACSM\u2019s Guidelines for Exercise Testing and Prescription the Ninth Edition-A Preview, Vasa Ninth Edit","author":"Pescatello","key":"10.1016\/j.cct.2024.107630_bb0335"},{"key":"10.1016\/j.cct.2024.107630_bb0340","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1177\/13524585231204446","article-title":"The MoXFo initiative - adherence: exercise adherence, compliance and sustainability among people with multiple sclerosis: an overview and roadmap for research","volume":"29","author":"Motl","year":"2023","journal-title":"Mult. Scler."},{"key":"10.1016\/j.cct.2024.107630_bb0345","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1054\/math.2000.0372","article-title":"PEDro. A database of randomized trials and systematic reviews in physiotherapy","volume":"5","author":"Sherrington","year":"2000","journal-title":"Man. Ther."},{"year":"2012","series-title":"The effects of acute exercise on cognitive performance: A meta-analysis","author":"Chang","key":"10.1016\/j.cct.2024.107630_bb0350"},{"key":"10.1016\/j.cct.2024.107630_bb0355","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00234-016-1767-x","article-title":"Exercise training effects on memory and hippocampal viscoelasticity in multiple sclerosis: a novel application of magnetic resonance elastography","volume":"59","author":"Sandroff","year":"2017","journal-title":"Neuroradiology"},{"key":"10.1016\/j.cct.2024.107630_bb0360","article-title":"Treadmill walking exercise training and brain function in multiple sclerosis: preliminary evidence setting the stage for a network-based approach to rehabilitation","volume":"4","author":"Sandroff","year":"2018","journal-title":"Mult. Scler. J. Exp. Transl. Clin."},{"key":"10.1016\/j.cct.2024.107630_bb0365","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1177\/1352458517709955","article-title":"A randomized controlled trial to treat impaired learning and memory in multiple sclerosis: the self-GEN trial","volume":"24","author":"Goverover","year":"2018","journal-title":"Mult. Scler. J."}],"container-title":["Contemporary Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714424002131?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714424002131?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T07:20:16Z","timestamp":1723792816000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551714424002131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":73,"alternative-id":["S1551714424002131"],"URL":"https:\/\/doi.org\/10.1016\/j.cct.2024.107630","relation":{},"ISSN":["1551-7144"],"issn-type":[{"type":"print","value":"1551-7144"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rationale and methodology for examining the combination of aerobic exercise and cognitive rehabilitation on new learning and memory in persons with multiple sclerosis and mobility disability: Protocol for a randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Contemporary Clinical Trials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cct.2024.107630","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107630"}}