{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:09:35Z","timestamp":1778821775828,"version":"3.51.4"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008361","name":"Danish Multiple Sclerosis Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008361","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006309","name":"Riisfort Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006309","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010809","name":"Jascha Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contemporary Clinical Trials"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.cct.2026.108317","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T07:29:36Z","timestamp":1776238176000},"page":"108317","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Effects of supervised progressive resistance training on corticospinal excitability in persons with multiple sclerosis: A randomized controlled trial protocol for the NEXIMS study"],"prefix":"10.1016","volume":"165","author":[{"given":"Therese M.","family":"Andersen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hjalte","family":"Riis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice","family":"Tankisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sepehr","family":"Mamoei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Langeskov-Christensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrik","family":"Dalgas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesper","family":"Lundbye-Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars G.","family":"Hvid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cct.2026.108317_bb0005","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/6430596","article-title":"Transcranial magnetic stimulation as a potential biomarker in multiple sclerosis: a systematic review with recommendations for future research","volume":"2019","author":"Snow","year":"2019","journal-title":"Neural Plast."},{"issue":"5","key":"10.1016\/j.cct.2026.108317_bb0010","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/ane.13289","article-title":"Neurophysiological impairments in multiple sclerosis-central and peripheral motor pathways","volume":"142","author":"Mamoei","year":"2020","journal-title":"Acta Neurol. Scand."},{"issue":"8","key":"10.1016\/j.cct.2026.108317_bb0015","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1007\/s40279-021-01453-6","article-title":"A critical systematic review of current evidence on the effects of physical exercise on whole\/regional grey matter brain volume in populations at risk of neurodegeneration","volume":"51","author":"Hvid","year":"2021","journal-title":"Sports Med."},{"key":"10.1016\/j.cct.2026.108317_bb0020","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.707675","article-title":"Neuroplasticity and motor rehabilitation in multiple sclerosis: a systematic review on MRI markers of functional and structural changes","volume":"15","author":"Tavazzi","year":"2021","journal-title":"Front. Neurosci."},{"issue":"10","key":"10.1016\/j.cct.2026.108317_bb0025","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1007\/s00702-013-1080-3","article-title":"Multiple sclerosis is primarily a neurodegenerative disease","volume":"120","author":"Chaudhuri","year":"2013","journal-title":"J. Neural Transm. (Vienna)"},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0030","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1056\/NEJMra1401483","article-title":"Multiple sclerosis","volume":"378","author":"Reich","year":"2018","journal-title":"N. Engl. J. Med."},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0035","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s00415-006-0334-5","article-title":"Motor evoked potentials in multiple sclerosis patients without walking limitation: amplitude vs. conduction time abnormalities","volume":"254","author":"Gagliardo","year":"2007","journal-title":"J. Neurol."},{"key":"10.1016\/j.cct.2026.108317_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2023.104714","article-title":"The association between brain volume loss and disability in multiple sclerosis: a systematic review","volume":"74","author":"Matthews","year":"2023","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"3","key":"10.1016\/j.cct.2026.108317_bb0045","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/ana.21719","article-title":"Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis","volume":"66","author":"Vogt","year":"2009","journal-title":"Ann. Neurol."},{"issue":"Pt 4","key":"10.1016\/j.cct.2026.108317_bb0050","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1093\/brain\/awn030","article-title":"Regional hippocampal atrophy in multiple sclerosis","volume":"131","author":"Sicotte","year":"2008","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.cct.2026.108317_bb0055","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2217\/nmt.15.71","article-title":"Thalamus volume and ambulation in multiple sclerosis: a cross-sectional study","volume":"6","author":"Motl","year":"2016","journal-title":"Neurodegener. Dis. Manag."},{"issue":"4","key":"10.1016\/j.cct.2026.108317_bb0060","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1212\/WNL.0000000000003542","article-title":"Brain MRI atrophy quantification in MS: from methods to clinical application","volume":"88","author":"Rocca","year":"2017","journal-title":"Neurology"},{"issue":"Suppl. 1","key":"10.1016\/j.cct.2026.108317_bb0065","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.msard.2016.07.003","article-title":"Brain health: time matters in multiple sclerosis","volume":"9","author":"Giovannoni","year":"2016","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.cct.2026.108317_bb0070","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jns.2017.03.022","article-title":"Muscle strength and power in persons with multiple sclerosis - a systematic review and meta-analysis","volume":"376","author":"J\u00f8rgensen","year":"2017","journal-title":"J. Neurol. Sci."},{"issue":"6","key":"10.1016\/j.cct.2026.108317_bb0075","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/mus.20038","article-title":"Functional relationships of central and peripheral muscle alterations in multiple sclerosis","volume":"29","author":"Ng","year":"2004","journal-title":"Muscle Nerve"},{"issue":"10","key":"10.1016\/j.cct.2026.108317_bb0080","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1002\/1097-4598(200010)23:10<1534::AID-MUS9>3.0.CO;2-D","article-title":"Contractile properties and fatigue of quadriceps muscles in multiple sclerosis","volume":"23","author":"de Haan","year":"2000","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.cct.2026.108317_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2020.111025","article-title":"Lower extremity muscle strength across the adult lifespan in multiple sclerosis: implications for walking and stair climbing capacity","author":"Sieljacks","year":"2020","journal-title":"Exp. Gerontol."},{"issue":"4","key":"10.1016\/j.cct.2026.108317_bb0090","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1177\/1545968320907074","article-title":"Accelerated trajectories of walking capacity across the adult life span in persons with multiple sclerosis: an underrecognized challenge","volume":"34","author":"Hvid","year":"2020","journal-title":"Neurorehabil. Neural Repair"},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0095","first-page":"207","article-title":"Walking capacity and ability are more impaired in progressive compared to relapsing type of multiple sclerosis","volume":"51","author":"Feys","year":"2015","journal-title":"Eur. J. Phys. Rehabil. Med."},{"issue":"1","key":"10.1016\/j.cct.2026.108317_bb0100","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2522\/ptj.20130588","article-title":"Associations of upper limb disability measures on different levels of the international classification of functioning, disability and health in people with multiple sclerosis","volume":"95","author":"Lamers","year":"2015","journal-title":"Phys. Ther."},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0105","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.msard.2015.01.002","article-title":"Relationship between muscle strength parameters and functional capacity in persons with mild to moderate degree multiple sclerosis","volume":"4","author":"Kj\u00f8lhede","year":"2015","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"1","key":"10.1016\/j.cct.2026.108317_bb0110","doi-asserted-by":"crossref","DOI":"10.1177\/20552173251326171","article-title":"Implications of maximal muscle strength and aerobic capacity for lower extremity physical function in people with multiple sclerosis-a cross-sectional study","volume":"11","author":"Taul-Madsen","year":"2025","journal-title":"Multiple Sclerosis J. Exp. Transl. Clin."},{"issue":"9648","key":"10.1016\/j.cct.2026.108317_bb0115","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1016\/S0140-6736(08)61620-7","article-title":"Multiple sclerosis","volume":"372","author":"Compston","year":"2008","journal-title":"Lancet"},{"issue":"10130","key":"10.1016\/j.cct.2026.108317_bb0120","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/S0140-6736(18)30481-1","article-title":"Multiple sclerosis","volume":"391","author":"Thompson","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.cct.2026.108317_bb0125","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.msard.2017.01.007","article-title":"Is multiple sclerosis a length-dependent central axonopathy? The case for therapeutic lag and the asynchronous progressive MS hypotheses","volume":"12","author":"Giovannoni","year":"2017","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.cct.2026.108317_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2021.111347","article-title":"Lower extremity muscle power - a critical determinant of physical function in aging and multiple sclerosis","volume":"150","author":"Stagsted","year":"2021","journal-title":"Exp. Gerontol."},{"issue":"4","key":"10.1016\/j.cct.2026.108317_bb0135","first-page":"562","article-title":"The importance of neuromuscular rate of force development for physical function in aging and common neurodegenerative disorders - a systematic review","volume":"22","author":"Lomborg","year":"2022","journal-title":"J. Musculoskelet. Neuronal Interact."},{"issue":"4","key":"10.1016\/j.cct.2026.108317_bb0140","doi-asserted-by":"crossref","DOI":"10.1177\/20552173231218127","article-title":"The six spot step test is superior in detecting walking capacity impairments compared to short- and long-distance walk tests in persons with multiple sclerosis","volume":"9","author":"Skjerb\u00e6k","year":"2023","journal-title":"Multiple Sclerosis J. Exp. Transl. Clin."},{"key":"10.1016\/j.cct.2026.108317_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2022.104082","article-title":"Identification of disability status in persons with multiple sclerosis by lower limb neuromuscular function - emphasis on rate of force development","volume":"67","author":"Taul-Madsen","year":"2022","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0150","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.rehab.2019.11.005","article-title":"The importance of lower-extremity muscle strength for lower-limb functional capacity in multiple sclerosis: systematic review","volume":"63","author":"Ramari","year":"2020","journal-title":"Ann. Phys. Rehabil. Med."},{"issue":"3","key":"10.1016\/j.cct.2026.108317_bb0155","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/ane.12881","article-title":"Perceptions on the value of bodily functions in multiple sclerosis","volume":"137","author":"Heesen","year":"2018","journal-title":"Acta Neurol. Scand."},{"issue":"3","key":"10.1016\/j.cct.2026.108317_bb0160","article-title":"Which symptoms contribute the most to patients' perception of health in multiple sclerosis?","volume":"3","author":"Green","year":"2017","journal-title":"Mult. Scler. J. Exp. Transl. Clin."},{"issue":"5","key":"10.1016\/j.cct.2026.108317_bb0165","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1111\/j.1468-1331.2010.03149.x","article-title":"Peripheral nervous system involvement in multiple sclerosis","volume":"18","author":"Gartzen","year":"2011","journal-title":"Eur. J. Neurol."},{"issue":"4","key":"10.1016\/j.cct.2026.108317_bb0170","first-page":"32","article-title":"Electrodiagnostic evaluation of peripheral nervous system changes in patients with multiple sclerosis","volume":"20","author":"Ayromlou","year":"2013","journal-title":"Malays. J. Med. Sci."},{"issue":"3","key":"10.1016\/j.cct.2026.108317_bb0175","doi-asserted-by":"crossref","DOI":"10.1177\/2055217318783352","article-title":"Costs and quality of life by disability among people with multiple sclerosis: a register-based study in Sweden","volume":"4","author":"Gyllensten","year":"2018","journal-title":"Multiple Sclerosis J. Exp. Transl. Clin."},{"issue":"11","key":"10.1016\/j.cct.2026.108317_bb0180","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s11910-019-1002-3","article-title":"Exercise as medicine in multiple sclerosis-time for a paradigm shift: preventive, symptomatic, and disease-modifying aspects and perspectives","volume":"19","author":"Dalgas","year":"2019","journal-title":"Curr. Neurol. Neurosci. Rep."},{"issue":"13","key":"10.1016\/j.cct.2026.108317_bb0185","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1177\/13524585231204459","article-title":"Safety of exercise training in multiple sclerosis: an updated systematic review and meta-analysis","volume":"29","author":"Learmonth","year":"2023","journal-title":"Mult. Scler."},{"issue":"10","key":"10.1016\/j.cct.2026.108317_bb0190","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1016\/j.apmr.2021.03.026","article-title":"Is aerobic or resistance training the most effective exercise modality for improving lower extremity physical function and perceived fatigue in people with multiple sclerosis? A systematic review and meta-analysis","volume":"102","author":"Taul-Madsen","year":"2021","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"9","key":"10.1016\/j.cct.2026.108317_bb0195","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1177\/1352458512437418","article-title":"Multiple sclerosis and progressive resistance training: a systematic review","volume":"18","author":"Kj\u00f8lhede","year":"2012","journal-title":"Mult. Scler."},{"issue":"10","key":"10.1016\/j.cct.2026.108317_bb0200","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1177\/1352458517722645","article-title":"Can resistance training impact MRI outcomes in relapsing-remitting multiple sclerosis?","volume":"24","author":"Kj\u00f8lhede","year":"2018","journal-title":"Mult. Scler."},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0205","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s00421-010-1519-2","article-title":"Enhanced neural drive after maximal strength training in multiple sclerosis patients","volume":"110","author":"Fimland","year":"2010","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.cct.2026.108317_bb0210","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.msard.2019.01.034","article-title":"How much does balance and muscle strength impact walking in persons with multiple sclerosis? - a cross-sectional study","volume":"29","author":"Callesen","year":"2019","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.cct.2026.108317_bb0215","article-title":"Changes in walking speed following resistance training in people with multiple sclerosis: a systematic review and meta-analysis","author":"McManaman","year":"2024","journal-title":"PM R"},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0220","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1177\/13524585241305496","article-title":"A head-to-head comparison of the effects of aerobic versus resistance training on physical capacity and physical function in people with multiple sclerosis: results from the MSBOOST trial","volume":"31","author":"Taul-Madsen","year":"2025","journal-title":"Mult. Scler."},{"key":"10.1016\/j.cct.2026.108317_bb0225","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2021.645240","article-title":"Can enhancing neuronal activity improve myelin repair in multiple sclerosis?","volume":"15","author":"Maas","year":"2021","journal-title":"Front. Cell. Neurosci."},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0230","doi-asserted-by":"crossref","first-page":"e203","DOI":"10.1212\/WNL.0000000000011241","article-title":"Efficacy of high-intensity aerobic exercise on brain MRI measures in multiple sclerosis","volume":"96","author":"Langeskov-Christensen","year":"2021","journal-title":"Neurology"},{"issue":"10","key":"10.1016\/j.cct.2026.108317_bb0235","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1177\/13524585221079200","article-title":"Investigating the potential disease-modifying and neuroprotective efficacy of exercise therapy early in the disease course of multiple sclerosis: the early multiple sclerosis exercise study (EMSES)","volume":"28","author":"Riemenschneider","year":"2022","journal-title":"Mult. Scler."},{"issue":"8","key":"10.1016\/j.cct.2026.108317_bb0240","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S1474-4422(22)00219-8","article-title":"Exercise training and neuroprotection in multiple sclerosis","volume":"21","author":"Hvid","year":"2022","journal-title":"Lancet Neurol."},{"issue":"6","key":"10.1016\/j.cct.2026.108317_bb0245","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1007\/s40279-020-01258-z","article-title":"Determining the sites of neural adaptations to resistance training: a systematic review and meta-analysis","volume":"50","author":"Siddique","year":"2020","journal-title":"Sports Med."},{"key":"10.1016\/j.cct.2026.108317_bb0250","doi-asserted-by":"crossref","first-page":"422","DOI":"10.3389\/fneur.2020.00422","article-title":"Walking training enhances corticospinal excitability in progressive multiple sclerosis-a pilot study","volume":"11","author":"Chaves","year":"2020","journal-title":"Front. Neurol."},{"issue":"10","key":"10.1016\/j.cct.2026.108317_bb0255","doi-asserted-by":"crossref","first-page":"e0299611","DOI":"10.1371\/journal.pone.0299611","article-title":"A 12-week in-phase bilateral upper limb exercise protocol promoted neuroplastic and clinical changes in people with relapsing remitting multiple sclerosis: a registered report randomized single-case concurrent multiple baseline study","volume":"19","author":"Sokratous","year":"2024","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.cct.2026.108317_bb0260","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/s13102-023-00790-5","article-title":"Task-oriented exercise effects on walking and corticospinal excitability in multiple sclerosis: protocol for a randomized controlled trial","volume":"15","author":"Moslemi","year":"2023","journal-title":"BMC Sports Sci. Med. Rehabil."},{"issue":"9","key":"10.1016\/j.cct.2026.108317_bb0265","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1016\/j.apmr.2013.05.015","article-title":"Development of evidence-informed physical activity guidelines for adults with multiple sclerosis","volume":"94","author":"Latimer-Cheung","year":"2013","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"11","key":"10.1016\/j.cct.2026.108317_bb0270","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1111\/ejn.13710","article-title":"Corticospinal responses following strength training: a systematic review and meta-analysis","volume":"46","author":"Kidgell","year":"2017","journal-title":"Eur. J. Neurosci."},{"issue":"4","key":"10.1016\/j.cct.2026.108317_bb0275","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1249\/JES.0000000000000229","article-title":"Assessment of neuroplasticity with strength training","volume":"48","author":"Aagaard","year":"2020","journal-title":"Exerc. Sport Sci. Rev."},{"key":"10.1016\/j.cct.2026.108317_bb0280","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neubiorev.2020.12.019","article-title":"Functional relevance of resistance training-induced neuroplasticity in health and disease","volume":"122","author":"Hortob\u00e1gyi","year":"2021","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"Pt 2","key":"10.1016\/j.cct.2026.108317_bb0285","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1113\/jphysiol.2002.024463","article-title":"The sites of neural adaptation induced by resistance training in humans","volume":"544","author":"Carroll","year":"2002","journal-title":"J. Physiol."},{"issue":"4","key":"10.1016\/j.cct.2026.108317_bb0290","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1152\/japplphysiol.01408.2004","article-title":"Motor skill training and strength training are associated with different plastic changes in the central nervous system","volume":"99","author":"Jensen","year":"2005","journal-title":"J. Appl. Physiol."},{"issue":"7206","key":"10.1016\/j.cct.2026.108317_bb0295","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1136\/bmj.319.7206.375","article-title":"Understanding controlled trials. Randomisation methods: concealment","volume":"319","author":"Torgerson","year":"1999","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.cct.2026.108317_bb0300","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1212\/WNL.60.1.31","article-title":"Measuring the impact of MS on walking ability: the 12-item MS walking scale (MSWS-12)","volume":"60","author":"Hobart","year":"2003","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.cct.2026.108317_bb0305","first-page":"333","article-title":"The use of transcranial magnetic stimulation to evaluate cortical excitability of lower limb musculature: challenges and opportunities","volume":"36","author":"Kesar","year":"2018","journal-title":"Restor. Neurol. Neurosci."},{"issue":"3","key":"10.1016\/j.cct.2026.108317_bb0310","first-page":"584","article-title":"Prediction of one repetition maximum strength from multiple repetition maximum testing and anthropometry","volume":"20","author":"Reynolds","year":"2006","journal-title":"J. Strength Cond. Res."},{"issue":"6","key":"10.1016\/j.cct.2026.108317_bb0315","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1080\/00222895.2022.2061409","article-title":"Determining the corticospinal responses and cross-transfer of ballistic motor performance in young and older adults: a systematic review and meta-analysis","volume":"54","author":"Woldeamanuel","year":"2022","journal-title":"J. Mot. Behav."},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0320","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.neuron.2007.06.026","article-title":"Transcranial magnetic stimulation: a primer","volume":"55","author":"Hallett","year":"2007","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0325","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.jneumeth.2011.11.020","article-title":"Stimulating deep cortical structures with the batwing coil: how to determine the intensity for transcranial magnetic stimulation using coil-cortex distance","volume":"204","author":"Cai","year":"2012","journal-title":"J. Neurosci. Methods"},{"issue":"5","key":"10.1016\/j.cct.2026.108317_bb0330","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.clinph.2012.01.010","article-title":"A practical guide to diagnostic transcranial magnetic stimulation: report of an IFCN committee","volume":"123","author":"Groppa","year":"2012","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.cct.2026.108317_bb0335","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1113\/jphysiol.1993.sp019912","article-title":"Corticocortical inhibition in human motor cortex","volume":"471","author":"Kujirai","year":"1993","journal-title":"J. Physiol."},{"issue":"3","key":"10.1016\/j.cct.2026.108317_bb0340","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1152\/jn.00207.2023","article-title":"Corticospinal excitability across lower limb muscles in humans","volume":"130","author":"Eisner-Janowicz","year":"2023","journal-title":"J. Neurophysiol."},{"issue":"5","key":"10.1016\/j.cct.2026.108317_bb0345","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S1050-6411(00)00027-4","article-title":"Development of recommendations for SEMG sensors and sensor placement procedures","volume":"10","author":"Hermens","year":"2000","journal-title":"J. Electromyogr. Kinesiol."},{"key":"10.1016\/j.cct.2026.108317_bb0350","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.exger.2016.03.018","article-title":"Voluntary muscle activation improves with power training and is associated with changes in gait speed in mobility-limited older adults - a randomized controlled trial","volume":"80","author":"Hvid","year":"2016","journal-title":"Exp. Gerontol."},{"issue":"4","key":"10.1016\/j.cct.2026.108317_bb0355","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1152\/physrev.2001.81.4.1725","article-title":"Spinal and supraspinal factors in human muscle fatigue","volume":"81","author":"Gandevia","year":"2001","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cct.2026.108317_bb0360","doi-asserted-by":"crossref","first-page":"103208","DOI":"10.1016\/j.jbi.2019.103208","article-title":"The REDCap consortium: building an international community of software platform partners","volume":"95","author":"Harris","year":"2019","journal-title":"J. Biomed. Inform."},{"issue":"2","key":"10.1016\/j.cct.2026.108317_bb0365","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J. Biomed. Inform."}],"container-title":["Contemporary Clinical Trials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714426001035?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551714426001035?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:27:50Z","timestamp":1778819270000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551714426001035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":73,"alternative-id":["S1551714426001035"],"URL":"https:\/\/doi.org\/10.1016\/j.cct.2026.108317","relation":{},"ISSN":["1551-7144"],"issn-type":[{"value":"1551-7144","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of supervised progressive resistance training on corticospinal excitability in persons with multiple sclerosis: A randomized controlled trial protocol for the NEXIMS study","name":"articletitle","label":"Article Title"},{"value":"Contemporary Clinical Trials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cct.2026.108317","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"108317"}}