{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T12:17:19Z","timestamp":1768738639399,"version":"3.49.0"},"reference-count":136,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.jp","theclinics.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Dental Clinics of North America"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.cden.2024.07.002","type":"journal-article","created":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T11:56:30Z","timestamp":1723031790000},"page":"603-617","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Systemic Factors Affecting Prognosis in Periodontics"],"prefix":"10.1016","volume":"68","author":[{"given":"Priyanka Kodaganallur","family":"Pitchumani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srishti","family":"Parekh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Rachana Hegde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davis C.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.cden.2024.07.002_bib1","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1177\/0022034521995157","article-title":"Host Modulation and Treatment of Periodontal Disease","volume":"100","author":"Balta","year":"2021","journal-title":"J\u00a0Dent Res"},{"issue":"7","key":"10.1016\/j.cden.2024.07.002_bib2","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1007\/s00784-019-03091-9","article-title":"Patient-, tooth-, and dentist-related factors influencing long-term tooth retention after resective therapy in an academic setting-a retrospective study","volume":"24","author":"El Sayed","year":"2020","journal-title":"Clin Oral Investig"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib3","doi-asserted-by":"crossref","first-page":"324","DOI":"10.4103\/0972-124X.100905","article-title":"Risk assessment for periodontal disease","volume":"16","author":"Koshi","year":"2012","journal-title":"J\u00a0Indian Soc Periodontol"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib4","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1600-0757.2012.00457.x","article-title":"Risk factors for periodontal disease","volume":"62","author":"Genco","year":"2000","journal-title":"Periodontol"},{"key":"10.1016\/j.cden.2024.07.002_bib5","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1046\/j.0906-6713.2003.003429.x","article-title":"Detection of localized tooth-related factors that predispose to periodontal infections","volume":"34","author":"Matthews","year":"2004","journal-title":"Periodontol 2000"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib6","first-page":"560","article-title":"The 2018 classification of periodontal diseases: Its predictive value for tooth loss","volume":"93","author":"El Sayed","year":"2022","journal-title":"J\u00a0Periodontol"},{"issue":"10","key":"10.1016\/j.cden.2024.07.002_bib7","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1111\/jcpe.13167","article-title":"Longitudinal evaluation of periodontitis and tooth loss among older adults","volume":"46","author":"Nilsson","year":"2019","journal-title":"J\u00a0Clin Periodontol"},{"issue":"7","key":"10.1016\/j.cden.2024.07.002_bib8","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/jcpe.13118","article-title":"Predictors for tooth loss in periodontitis patients: Systematic review and meta-analysis","volume":"46","author":"Helal","year":"2019","journal-title":"J\u00a0Clin Periodontol"},{"issue":"12","key":"10.1016\/j.cden.2024.07.002_bib9","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1111\/jcpe.12782","article-title":"Natural history of periodontitis: Disease progression and tooth loss over 40 years","volume":"44","author":"Ramseier","year":"2017","journal-title":"J\u00a0Clin Periodontol"},{"issue":"8","key":"10.1016\/j.cden.2024.07.002_bib10","first-page":"1134","article-title":"Tooth loss and periodontitis in older individuals: results from the Swedish National Study on Aging and Care","volume":"84","author":"Renvert","year":"2013","journal-title":"J\u00a0Periodontol"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib11","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1034\/j.1600-051X.1999.260607.x","article-title":"Longitudinal study of predictive factors for periodontal disease and tooth loss","volume":"26","author":"Machtei","year":"1999","journal-title":"J\u00a0Clin Periodontol"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib12","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/00220345211037977","article-title":"Periodontitis and Accelerated Biological Aging: A Geroscience Approach","volume":"101","author":"Baima","year":"2022","journal-title":"J\u00a0Dent Res"},{"issue":"13","key":"10.1016\/j.cden.2024.07.002_bib13","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1177\/00220345221110108","article-title":"TLR9 Mediates Periodontal Aging by Fostering Senescence and Inflammaging","volume":"101","author":"Albuquerque-Souza","year":"2022","journal-title":"J\u00a0Dent Res"},{"issue":"8","key":"10.1016\/j.cden.2024.07.002_bib14","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1177\/00220345231154567","article-title":"The Emerging Role of Accelerated Cellular Senescence in Periodontitis","volume":"102","author":"Aquino-Martinez","year":"2023","journal-title":"J\u00a0Dent Res"},{"issue":"10","key":"10.1016\/j.cden.2024.07.002_bib15","article-title":"Cellular Senescence and Periodontitis: Mechanisms and Therapeutics","volume":"11","author":"Chen","year":"2022","journal-title":"Biology (Basel)"},{"issue":"Suppl 16","key":"10.1016\/j.cden.2024.07.002_bib16","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/clr.13288","article-title":"Effect of advanced age and\/or systemic medical conditions on dental implant survival: A systematic review and meta-analysis","volume":"29","author":"Schimmel","year":"2018","journal-title":"Clin Oral Implants Res"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib17","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/clr.13704","article-title":"How old is old for implant therapy in terms of implant survival and marginal bone levels after 5-11 years?","volume":"32","author":"Et\u00f6z","year":"2021","journal-title":"Clin Oral Implants Res"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib18","doi-asserted-by":"crossref","first-page":"351","DOI":"10.4103\/jispcd.JISPCD_380_17","article-title":"Factors Affecting the Survival Rate of Dental Implants: A Retrospective Study","volume":"7","author":"Raikar","year":"2017","journal-title":"J\u00a0Int Soc Prev Community Dent"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib19","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s40292-020-00392-z","article-title":"Periodontitis and Hypertension: Is the Association Causal?","volume":"27","author":"Del Pinto","year":"2020","journal-title":"High Blood Press Cardiovasc Prev"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib20","first-page":"e13","volume":"71","author":"Whelton","year":"2018","journal-title":"Hypertension"},{"issue":"12","key":"10.1016\/j.cden.2024.07.002_bib21","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1097\/HJH.0000000000003480","volume":"41","author":"Mancia","year":"2023","journal-title":"J\u00a0Hypertens"},{"issue":"Suppl 1","key":"10.1016\/j.cden.2024.07.002_bib22","first-page":"S183","article-title":"Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations","volume":"89","author":"Albandar","year":"2018","journal-title":"J\u00a0Periodontol"},{"issue":"9","key":"10.1016\/j.cden.2024.07.002_bib23","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1056\/NEJMoa063186","article-title":"Treatment of periodontitis and endothelial function","volume":"356","author":"Tonetti","year":"2007","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib24","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1002\/jbmr.1594","article-title":"Deletion of \u03b2-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation","volume":"27","author":"Pierroz","year":"2012","journal-title":"J\u00a0Bone Miner Res"},{"issue":"12","key":"10.1016\/j.cden.2024.07.002_bib25","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1111\/jcpe.12632","article-title":"Propranolol enhances bone healing and implant osseointegration in rats tibiae","volume":"43","author":"Al-Subaie","year":"2016","journal-title":"J\u00a0Clin Periodontol"},{"key":"10.1016\/j.cden.2024.07.002_bib26","doi-asserted-by":"crossref","first-page":"s35","DOI":"10.11607\/jomi.19suppl.g3","article-title":"The Effects of Systemic Diseases and Medications on Implant Osseointegration: A Systematic Review","volume":"34","author":"Aghaloo","year":"2019","journal-title":"Int J Oral Maxillofac Implants"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib27","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s12020-014-0167-4","article-title":"Antihypertensive medications, bone mineral density, and fractures: a review of old cardiac drugs that provides new insights into osteoporosis","volume":"46","author":"Ghosh","year":"2014","journal-title":"Endocrine"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib28","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1111\/cid.12414","article-title":"Antihypertensive Medications and the Survival Rate of Osseointegrated Dental Implants: A Cohort Study","volume":"18","author":"Wu","year":"2016","journal-title":"Clin Implant Dent Relat Res"},{"key":"10.1016\/j.cden.2024.07.002_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.archoralbio.2021.105184","article-title":"Are periodontal diseases associated with sleep duration or sleep quality? A systematic review","volume":"129","author":"Muniz","year":"2021","journal-title":"Arch Oral Biol"},{"issue":"5","key":"10.1016\/j.cden.2024.07.002_bib30","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/jcpe.12713","article-title":"The association between periodontitis and sleep duration","volume":"44","author":"Romandini","year":"2017","journal-title":"J\u00a0Clin Periodontol"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0234487","article-title":"Is inadequate sleep a potential risk factor for periodontitis?","volume":"15","author":"Alhassani","year":"2020","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib32","doi-asserted-by":"crossref","first-page":"97","DOI":"10.5665\/sleep.1594","article-title":"A\u00a0prospective study of sleep duration and pneumonia risk in women","volume":"35","author":"Patel","year":"2012","journal-title":"Sleep"},{"issue":"8","key":"10.1016\/j.cden.2024.07.002_bib33","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1111\/jcpe.13813","article-title":"Healthy lifestyles are associated with a better response to periodontal therapy: A prospective cohort study","volume":"50","author":"Marruganti","year":"2023","journal-title":"J\u00a0Clin Periodontol"},{"issue":"11","key":"10.1016\/j.cden.2024.07.002_bib34","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1111\/jcpe.12473","article-title":"Longitudinal effects of systemic inflammation markers on periodontitis","volume":"42","author":"Pink","year":"2015","journal-title":"J\u00a0Clin Periodontol"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib35","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.sleep.2007.08.019","article-title":"Cytokines and pathological sleep","volume":"9","author":"Kapsimalis","year":"2008","journal-title":"Sleep Med"},{"key":"10.1016\/j.cden.2024.07.002_bib36","article-title":"Association of Sleep Duration with Tooth Loss and Periodontitis: Insights from the National Health and Nutrition Examination Surveys (2005-2020)","author":"Liu","year":"2023","journal-title":"Sleep Breath"},{"issue":"8","key":"10.1016\/j.cden.2024.07.002_bib37","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.5664\/jcsm.10600","article-title":"Inflammation biomarkers in OSA, chronic obstructive pulmonary disease, and chronic obstructive pulmonary disease\/OSA overlap syndrome","volume":"19","author":"Sanchez-Azofra","year":"2023","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib38","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1007\/s11325-015-1160-8","article-title":"Periodontitis and obstructive sleep apnea's bidirectional relationship: a systematic review and meta-analysis","volume":"19","author":"Al-Jewair","year":"2015","journal-title":"Sleep Breath"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib39","doi-asserted-by":"crossref","first-page":"e359","DOI":"10.4317\/jced.59478","article-title":"Is periodontitis associated with obstructive sleep apnea? A systematic review and meta-analysis","volume":"14","author":"Khodadadi","year":"2022","journal-title":"J\u00a0Clin Exp Dent"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib40","doi-asserted-by":"crossref","first-page":"44","DOI":"10.4103\/ijdr.IJDR_534_19","article-title":"Obstructive sleep apnea and periodontitis: A cross-sectional study","volume":"32","author":"Mukherjee","year":"2021","journal-title":"Indian J Dent Res"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib41","article-title":"Obstructive Sleep Apnea and Periodontal Disease: A Systematic Review","volume":"57","author":"Lembo","year":"2021","journal-title":"Medicina (Kaunas)"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib42","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.adaj.2023.12.004","article-title":"Sleep bruxism: The past, the present, and the future-evolution of a concept","volume":"155","author":"Thomas","year":"2024","journal-title":"J\u00a0Am Dent Assoc"},{"issue":"Suppl 18","key":"10.1016\/j.cden.2024.07.002_bib43","first-page":"S39","article-title":"Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP\/ORCA workshop on the boundaries between caries and periodontal diseases","volume":"44","author":"Chapple","year":"2017","journal-title":"J\u00a0Clin Periodontol"},{"issue":"9","key":"10.1016\/j.cden.2024.07.002_bib44","doi-asserted-by":"crossref","DOI":"10.3390\/nu8090530","article-title":"The Role of Nutrition in Periodontal Health: An Update","volume":"8","author":"Najeeb","year":"2016","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib45","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/jcpe.12483","article-title":"Serum vitamin B12 is inversely associated with periodontal progression and risk of tooth loss: a prospective cohort study","volume":"43","author":"Zong","year":"2016","journal-title":"J\u00a0Clin Periodontol"},{"issue":"7","key":"10.1016\/j.cden.2024.07.002_bib46","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1177\/0022034514534985","article-title":"Prospective Study of Serum 25-hydroxy Vitamin D and Tooth Loss","volume":"93","author":"Zhan","year":"2014","journal-title":"J\u00a0Dent Res"},{"issue":"8","key":"10.1016\/j.cden.2024.07.002_bib47","doi-asserted-by":"crossref","DOI":"10.3390\/nu12082255","article-title":"A\u00a0Pilot Study Examining Vitamin C Levels in Periodontal Patients","volume":"12","author":"Munday","year":"2020","journal-title":"Nutrients"},{"issue":"7","key":"10.1016\/j.cden.2024.07.002_bib48","first-page":"1084","article-title":"Effects of vitamin-B complex supplementation on periodontal wound healing","volume":"76","author":"Neiva","year":"2005","journal-title":"J\u00a0Periodontol"},{"issue":"6 Suppl","key":"10.1016\/j.cden.2024.07.002_bib49","doi-asserted-by":"crossref","first-page":"1505s","DOI":"10.1093\/ajcn\/83.6.1505S","article-title":"n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases","volume":"83","author":"Calder","year":"2006","journal-title":"Am J Clin Nutr"},{"issue":"8","key":"10.1016\/j.cden.2024.07.002_bib50","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17081202","article-title":"Role of Lipids in the Onset, Progression and Treatment of Periodontal Disease. A Systematic Review of Studies in Humans","volume":"17","author":"Varela-L\u00f3pez","year":"2016","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.cden.2024.07.002_bib51","first-page":"115","article-title":"Vitamin C and Its Role in Periodontal Diseases - The Past and the Present: A Narrative Review","volume":"18","author":"Van der Velden","year":"2020","journal-title":"Oral Health Prev Dent"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib52","first-page":"97","article-title":"Effect of vitamin E on periodontitis: Evidence and proposed mechanisms of action","volume":"63","author":"Shadisvaaran","year":"2021","journal-title":"J\u00a0Oral Biosci"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib53","doi-asserted-by":"crossref","DOI":"10.3390\/nu15061538","article-title":"Dietary and Nutraceutical Interventions as an Adjunct to Non-Surgical Periodontal Therapy-A Systematic Review","volume":"15","author":"Woelber","year":"2023","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib54","doi-asserted-by":"crossref","DOI":"10.3390\/nu12010268","article-title":"Do Dietary Supplements and Nutraceuticals Have Effects on Dental Implant Osseointegration? A Scoping Review","volume":"12","author":"Nastri","year":"2020","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib55","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s40729-022-00414-6","article-title":"Does vitamin D have an effect on osseointegration of dental implants? A systematic review","volume":"8","author":"Werny","year":"2022","journal-title":"Int J Implant Dent"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib56","doi-asserted-by":"crossref","first-page":"360","DOI":"10.4103\/njms.njms_192_22","article-title":"Significance of 25(OH) D3 in Early Dental Implant Failure (EDIF) during osseointegration-A systematic review","volume":"14","author":"Shah","year":"2023","journal-title":"Natl J Maxillofac Surg"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib57","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1007\/s10266-020-00565-1","article-title":"Evaluation of periodontal status and cytokine\/chemokine profile of GCF in patients with severe congenital neutropenia","volume":"109","author":"Acar","year":"2021","journal-title":"Odontology"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib58","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1007\/s10875-011-9572-0","article-title":"Mutations in the ELANE gene are associated with development of periodontitis in patients with severe congenital neutropenia","volume":"31","author":"Ye","year":"2011","journal-title":"J\u00a0Clin Immunol"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib59","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1177\/0022034513507956","article-title":"Neutrophil homeostasis and periodontal health in children and adults","volume":"93","author":"Hajishengallis","year":"2014","journal-title":"J\u00a0Dent Res"},{"issue":"5","key":"10.1016\/j.cden.2024.07.002_bib60","first-page":"473","article-title":"Periodontal findings in Cohen syndrome with chronic neutropenia","volume":"68","author":"Alaluusua","year":"1997","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.cden.2024.07.002_bib61","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.micpath.2015.09.003","article-title":"Role of bacteria in leukocyte adhesion deficiency-associated periodontitis","volume":"94","author":"Hajishengallis","year":"2016","journal-title":"Microb Pathog"},{"issue":"8","key":"10.1016\/j.cden.2024.07.002_bib62","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1586\/1744666X.2014.929944","article-title":"Etiology of leukocyte adhesion deficiency-associated periodontitis revisited: not a raging infection but a raging inflammatory response","volume":"10","author":"Hajishengallis","year":"2014","journal-title":"Expert Rev Clin Immunol"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib63","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph19063386","article-title":"Premature Loss of Deciduous Teeth as a Symptom of Systemic Disease: A Narrative Literature Review","volume":"19","author":"Spodzieja","year":"2022","journal-title":"Int J Environ Res Public Health"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib64","first-page":"159","article-title":"Severe periodontitis in a patient with cyclic neutropenia: a case report of long-term follow-up","volume":"15","author":"Lu","year":"2012","journal-title":"Chin J Dent Res"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib65","first-page":"307","article-title":"Cyclic neutropenia presenting as recurrent oral ulcers and periodontitis","volume":"37","author":"Chen","year":"2013","journal-title":"J\u00a0Clin Pediatr Dent. Spring"},{"issue":"5","key":"10.1016\/j.cden.2024.07.002_bib66","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1754-4505.2000.tb00017.x","article-title":"Early tooth loss due to cyclic neutropenia: long-term follow-up of one patient","volume":"20","author":"da Fonseca","year":"2000","journal-title":"Spec Care Dentist"},{"issue":"11","key":"10.1016\/j.cden.2024.07.002_bib67","first-page":"1921","article-title":"Periodontitis as a manifestation of chronic benign neutropenia","volume":"77","author":"Zaromb","year":"2006","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.cden.2024.07.002_bib68","doi-asserted-by":"crossref","first-page":"972598","DOI":"10.3389\/fgene.2022.972598","article-title":"Case report: Five-year periodontal management of a patient with two novel mutation sites in ELANE-induced cyclic neutropenia","volume":"13","author":"Lao","year":"2022","journal-title":"Front Genet"},{"issue":"14","key":"10.1016\/j.cden.2024.07.002_bib69","article-title":"Bleeding Disorders and Dental Implants: Review and Clinical Indications","volume":"12","author":"Bacci","year":"2023","journal-title":"J\u00a0Clin Med"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib70","first-page":"e572","article-title":"2-years retrospective observational case-control study on survival and marginal bone loss of implants in patients with hereditary coagulopathies","volume":"28","author":"P\u00e9rez-Fierro","year":"2023","journal-title":"Med Oral Patol Oral Cir Bucal"},{"issue":"Suppl 20","key":"10.1016\/j.cden.2024.07.002_bib71","first-page":"S162","article-title":"Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Papapanou","year":"2018","journal-title":"J\u00a0Clin Periodontol"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib72","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.identj.2021.01.016","article-title":"Impact of Smoking Cessation on Periodontal Tissues","volume":"72","author":"Duarte","year":"2022","journal-title":"Int Dent J"},{"issue":"7","key":"10.1016\/j.cden.2024.07.002_bib73","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph20075368","article-title":"Influence of Smoking on Periodontal and Implant Therapy: A Narrative Review","volume":"20","author":"Madi","year":"2023","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib74","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1186\/s12903-019-0930-2","article-title":"Effect of smoking cessation on tooth loss: a systematic review with meta-analysis","volume":"19","author":"Souto","year":"2019","journal-title":"BMC Oral Health"},{"issue":"12","key":"10.1016\/j.cden.2024.07.002_bib75","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1093\/ntr\/nty147","article-title":"Impact of Smoking Cessation on Periodontitis: A Systematic Review and Meta-analysis of Prospective Longitudinal Observational and Interventional Studies","volume":"21","author":"Leite","year":"2019","journal-title":"Nicotine Tob Res"},{"issue":"9","key":"10.1016\/j.cden.2024.07.002_bib76","article-title":"Smoking Cessation on Periodontal and Peri-Implant Health Status: A Systematic Review","volume":"10","author":"Caggiano","year":"2022","journal-title":"Dent J (Basel)"},{"key":"10.1016\/j.cden.2024.07.002_bib77","doi-asserted-by":"crossref","first-page":"72","DOI":"10.18332\/tid\/152112","article-title":"The impact of smoking on periodontal status and dental caries","volume":"20","author":"Beklen","year":"2022","journal-title":"Tob Induc Dis"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib78","article-title":"Periodontal and Peri-Implant Health Status in Traditional vs. Heat-Not-Burn Tobacco and Electronic Cigarettes Smokers: A Systematic Review","volume":"10","author":"D'Ambrosio","year":"2022","journal-title":"Dent J (Basel)"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib79","doi-asserted-by":"crossref","first-page":"101318","DOI":"10.1016\/j.jebdp.2019.04.002","article-title":"Effects of Electronic Cigarettes on Oral Cavity: A Systematic Review","volume":"19","author":"Ralho","year":"2019","journal-title":"J\u00a0Evid Based Dent Pract"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib80","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/prd.12450","article-title":"Illegal drugs and periodontal conditions","volume":"90","author":"Quaranta","year":"2022","journal-title":"Periodontol 2000"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib81","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1034\/j.1600-051X.2003.00157.x","article-title":"Epidemiologic risk factors for periodontal attachment loss among adults in the United States","volume":"30","author":"Hyman","year":"2003","journal-title":"J\u00a0Clin Periodontol"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib82","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/cre2.526","article-title":"Periodontal disease prevalence, extent, and risk associations in untreated individuals","volume":"8","author":"Alawaji","year":"2022","journal-title":"Clin Exp Dent Res"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib83","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1034\/j.1600-051X.2003.00272.x","article-title":"Tobacco smoking and risk for periodontal disease","volume":"30","author":"Bergstr\u00f6m","year":"2003","journal-title":"J\u00a0Clin Periodontol"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib84","first-page":"254","article-title":"Impact of cigarette smoking on clinical outcomes of periodontal flap surgical procedures: a systematic review and meta-analysis","volume":"86","author":"Kotsakis","year":"2015","journal-title":"J\u00a0Periodontol"},{"key":"10.1016\/j.cden.2024.07.002_bib85","doi-asserted-by":"crossref","DOI":"10.1007\/s10006-023-01172-4","article-title":"Levels of smoking and outcome measures of root coverage procedures: a systematic review and meta-analysis","author":"Moscowchi","year":"2023","journal-title":"Oral Maxillofac Surg"},{"key":"10.1016\/j.cden.2024.07.002_bib86","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3389\/fmicb.2020.00066","article-title":"The Impact of Smoking on Subgingival Microflora: From Periodontal Health to Disease","volume":"11","author":"Jiang","year":"2020","journal-title":"Front Microbiol"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib87","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/prd.12355","article-title":"Environmental factors and periodontal microbiome","volume":"85","author":"Buduneli","year":"2021","journal-title":"Periodontol 2000"},{"issue":"9","key":"10.1016\/j.cden.2024.07.002_bib88","first-page":"1210","article-title":"Effects of smoking and treatment status on periodontal bacteria: evidence that smoking influences control of periodontal bacteria at the mucosal surface of the gingival crevice","volume":"72","author":"Eggert","year":"2001","journal-title":"J\u00a0Periodontol"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib89","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1034\/j.1600-051X.2003.10284.x","article-title":"Hyperaemic response to cigarette smoking in healthy gingiva","volume":"30","author":"Mavropoulos","year":"2003","journal-title":"J\u00a0Clin Periodontol"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib90","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1097\/00006534-197804000-00013","article-title":"Nicotine and its effect on wound healing","volume":"61","author":"Mosely","year":"1978","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib91","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1046\/j.0904-2512.2001.joptest.doc.x","article-title":"Expression of ICAM-1 and E-selectin in gingival tissues of smokers and non-smokers with periodontitis","volume":"31","author":"Rezavandi","year":"2002","journal-title":"J\u00a0Oral Pathol Med"},{"issue":"7","key":"10.1016\/j.cden.2024.07.002_bib92","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1600-0765.1999.tb02267.x","article-title":"Potential mechanisms of susceptibility to periodontitis in tobacco smokers","volume":"34","author":"Palmer","year":"1999","journal-title":"J\u00a0Periodontal Res"},{"issue":"11","key":"10.1016\/j.cden.2024.07.002_bib93","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1034\/j.1600-051X.2003.00416.x","article-title":"Effect of smoking on gingival crevicular fluid cytokine profile during experimental gingivitis","volume":"30","author":"Giannopoulou","year":"2003","journal-title":"J\u00a0Clin Periodontol"},{"issue":"10","key":"10.1016\/j.cden.2024.07.002_bib94","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/j.1600-051X.1998.tb02368.x","article-title":"Clinical expression of TNF-alpha in smoking-associated periodontal disease","volume":"25","author":"Bostr\u00f6m","year":"1998","journal-title":"J\u00a0Clin Periodontol"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib95","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/j.1600-051X.1998.tb02428.x","article-title":"Influence of smoking on the outcome of periodontal surgery. A 5-year follow-up","volume":"25","author":"Bostr\u00f6m","year":"1998","journal-title":"J\u00a0Clin Periodontol"},{"issue":"5","key":"10.1016\/j.cden.2024.07.002_bib96","first-page":"717","article-title":"Effects of nicotine on the strength of attachment of gingival fibroblasts to glass and non-diseased human root surfaces","volume":"71","author":"Tanur","year":"2000","journal-title":"J\u00a0Periodontol"},{"issue":"5","key":"10.1016\/j.cden.2024.07.002_bib97","first-page":"518","article-title":"Effects of tobacco products on the attachment and growth of periodontal ligament fibroblasts","volume":"70","author":"James","year":"1999","journal-title":"J\u00a0Periodontol"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib98","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1034\/j.1600-051X.1999.260109.x","article-title":"Effects of nicotine on periodontal ligament fibroblasts in\u00a0vitro","volume":"26","author":"Giannopoulou","year":"1999","journal-title":"J\u00a0Clin Periodontol"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib99","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1034\/j.1600-0765.2002.00317.x","article-title":"The volatile fraction of cigarette smoke induces alterations in the human gingival fibroblast cytoskeleton","volume":"37","author":"Poggi","year":"2002","journal-title":"J\u00a0Periodontal Res"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib100","first-page":"425","article-title":"Volatile components of cigarette smoke: effect of acrolein and acetaldehyde on human gingival fibroblasts in\u00a0vitro","volume":"71","author":"Cattaneo","year":"2000","journal-title":"J\u00a0Periodontol"},{"issue":"1a","key":"10.1016\/j.cden.2024.07.002_bib101","doi-asserted-by":"crossref","first-page":"22s","DOI":"10.1016\/0002-9343(92)90623-J","article-title":"Smoking and wound healing","volume":"93","author":"Silverstein","year":"1992","journal-title":"Am J Med"},{"issue":"12","key":"10.1016\/j.cden.2024.07.002_bib102","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.2337\/diab.37.12.1595","article-title":"Banting lecture 1988. Role of insulin resistance in human disease","volume":"37","author":"Reaven","year":"1988","journal-title":"Diabetes"},{"issue":"16","key":"10.1016\/j.cden.2024.07.002_bib103","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241613011","article-title":"Periodontal Disease and Its Association with Metabolic Syndrome-A Comprehensive Review","volume":"24","author":"Aizenbud","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib104","article-title":"Hypertension and Its Associations with Dental Status: Data from the Dental, Oral, Medical Epidemiological (DOME) Nationwide Records-Based Study","volume":"10","author":"Almoznino","year":"2021","journal-title":"J\u00a0Clin Med"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib105","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/jcpe.12417","article-title":"Is weight gain associated with the incidence of periodontitis? A systematic review and meta-analysis","volume":"42","author":"Nascimento","year":"2015","journal-title":"J\u00a0Clin Periodontol"},{"key":"10.1016\/j.cden.2024.07.002_bib106","doi-asserted-by":"crossref","first-page":"999455","DOI":"10.3389\/fendo.2022.999455","article-title":"Obesity and periodontitis: A systematic review and updated meta-analysis","volume":"13","author":"Kim","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib107","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1210\/jc.2012-3552","article-title":"Clinical review: Association between metabolic syndrome and periodontitis: a systematic review and meta-analysis","volume":"98","author":"Nibali","year":"2013","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.cden.2024.07.002_bib108","doi-asserted-by":"crossref","first-page":"728987","DOI":"10.1155\/2013\/728987","article-title":"Tumor necrosis factor- \u03b1 and interleukin-6: potential interorgan inflammatory mediators contributing to destructive periodontal disease in obesity or metabolic syndrome","volume":"2013","author":"Khosravi","year":"2013","journal-title":"Mediators Inflamm"},{"issue":"6","key":"10.1016\/j.cden.2024.07.002_bib109","first-page":"e708","article-title":"Association between obesity and periodontal disease. A systematic review of epidemiological studies and controlled clinical trials","volume":"22","author":"Martinez-Herrera","year":"2017","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"10.1016\/j.cden.2024.07.002_bib110","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.bone.2018.05.019","article-title":"Defining osteoblast and adipocyte lineages in the bone marrow","volume":"118","author":"Pierce","year":"2019","journal-title":"Bone"},{"key":"10.1016\/j.cden.2024.07.002_bib111","first-page":"2643079","article-title":"The Relation between Periodontopathogenic Bacterial Levels and Resistin in the Saliva of Obese Type 2 Diabetic Patients","volume":"2017","author":"Al-Rawi","year":"2017","journal-title":"J\u00a0Diabetes Res"},{"issue":"12","key":"10.1016\/j.cden.2024.07.002_bib112","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1111\/jcpe.12634","article-title":"Does obesity influence the subgingival microbiota composition in periodontal health and disease?","volume":"43","author":"Maciel","year":"2016","journal-title":"J\u00a0Clin Periodontol"},{"issue":"10","key":"10.1016\/j.cden.2024.07.002_bib113","first-page":"1410","article-title":"Subgingival microbiota in overweight and obese young adults with no destructive periodontal disease","volume":"92","author":"de Andrade","year":"2021","journal-title":"J\u00a0Periodontol"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib114","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1600-051X.1997.tb01182.x","article-title":"The relationship between life-events and periodontitis. A case-control study","volume":"24","author":"Croucher","year":"1997","journal-title":"J\u00a0Clin Periodontol"},{"key":"10.1016\/j.cden.2024.07.002_bib115","doi-asserted-by":"crossref","first-page":"814177","DOI":"10.3389\/fpsyt.2021.814177","article-title":"The Role of the Oral Microbiota Related to Periodontal Diseases in Anxiety, Mood and Trauma- and Stress-Related Disorders","volume":"12","author":"Mart\u00ednez","year":"2021","journal-title":"Front Psychiatr"},{"issue":"7","key":"10.1016\/j.cden.2024.07.002_bib116","first-page":"711","article-title":"Relationship of stress, distress and inadequate coping behaviors to periodontal disease","volume":"70","author":"Genco","year":"1999","journal-title":"J\u00a0Periodontol"},{"issue":"7","key":"10.1016\/j.cden.2024.07.002_bib117","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1007\/s00784-019-03083-9","article-title":"Is there association between stress and periodontitis?","volume":"24","author":"Coelho","year":"2020","journal-title":"Clin Oral Investig"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib118","first-page":"293","article-title":"Association between psychological distress and chronic periodontitis in Sri Lankan adults","volume":"36","author":"Wellappulli","year":"2019","journal-title":"Community Dent Health"},{"issue":"19","key":"10.1016\/j.cden.2024.07.002_bib119","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph16193540","article-title":"Influence of Occupational Stress and Coping Style on Periodontitis among Japanese Workers: A Cross-Sectional Study","volume":"16","author":"Islam","year":"2019","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib120","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1601-5037.2009.00397.x","article-title":"The influence of academic stress on gingival inflammation","volume":"8","author":"Johannsen","year":"2010","journal-title":"Int J Dent Hyg"},{"issue":"9","key":"10.1016\/j.cden.2024.07.002_bib121","first-page":"1767","article-title":"Association of salivary levels of cortisol and dehydroepiandrosterone with periodontitis in older Japanese adults","volume":"78","author":"Ishisaka","year":"2007","journal-title":"J\u00a0Periodontol"},{"issue":"12","key":"10.1016\/j.cden.2024.07.002_bib124","first-page":"1755","article-title":"Catecholamine metabolites in urine, as chronic stress biomarkers, are associated with higher risk of chronic periodontitis in adults","volume":"85","author":"Mesa","year":"2014","journal-title":"J\u00a0Periodontol"},{"issue":"12","key":"10.1016\/j.cden.2024.07.002_bib123","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1111\/jcpe.12614","article-title":"Gingival crevicular fluid and saliva stress hormone levels in patients with chronic and aggressive periodontitis","volume":"43","author":"Cakmak","year":"2016","journal-title":"J\u00a0Clin Periodontol"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib122","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00784-019-03089-3","article-title":"The assessment of stress, depression, and inflammation as a collective risk factor for periodontal diseases: a systematic review","volume":"24","author":"Decker","year":"2020","journal-title":"Clin Oral Investig"},{"issue":"10","key":"10.1016\/j.cden.2024.07.002_bib125","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1111\/jcpe.12142","article-title":"The effects of stress on periodontal treatment: a longitudinal investigation using clinical and biological markers","volume":"40","author":"Bakri","year":"2013","journal-title":"J\u00a0Clin Periodontol"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib126","first-page":"287","article-title":"Salivary stress markers, stress, and periodontitis: a pilot study","volume":"82","author":"Rai","year":"2011","journal-title":"J\u00a0Periodontol"},{"issue":"3","key":"10.1016\/j.cden.2024.07.002_bib127","doi-asserted-by":"crossref","first-page":"e223","DOI":"10.1038\/emm.2015.127","article-title":"Chronic stress accelerates ligature-induced periodontitis by suppressing glucocorticoid receptor-\u03b1 signaling","volume":"48","author":"Lu","year":"2016","journal-title":"Exp Mol Med"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib128","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1600-0765.2012.01515.x","article-title":"Diazepam reverses the alveolar bone loss and hippocampal interleukin-1beta and interleukin-6 enhanced by conditioned fear stress in ligature-induced periodontal disease in rats","volume":"48","author":"Gomes","year":"2013","journal-title":"J\u00a0Periodontal Res"},{"key":"10.1016\/j.cden.2024.07.002_bib129","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.anaerobe.2013.09.001","article-title":"The effects of stress hormones on growth of selected periodontitis related bacteria","volume":"24","author":"Jentsch","year":"2013","journal-title":"Anaerobe"},{"issue":"5","key":"10.1016\/j.cden.2024.07.002_bib130","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1034\/j.1399-302X.2002.170506.x","article-title":"Stress and the periodontal diseases: effects of catecholamines on the growth of periodontal bacteria in\u00a0vitro","volume":"17","author":"Roberts","year":"2002","journal-title":"Oral Microbiol Immunol"},{"issue":"1","key":"10.1016\/j.cden.2024.07.002_bib131","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/prd.12398","article-title":"Oral health's inextricable connection to systemic health: Special populations bring to bear multimodal relationships and factors connecting periodontal disease to systemic diseases and conditions","volume":"87","author":"Kapila","year":"2021","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.cden.2024.07.002_bib132","doi-asserted-by":"crossref","first-page":"793898","DOI":"10.1155\/2015\/793898","article-title":"The Two-Way Association of Periodontal Infection with Systemic Disorders: An Overview","volume":"2015","author":"Nagpal","year":"2015","journal-title":"Mediators Inflamm"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib133","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25021024","article-title":"Mitochondrial Dysfunction in Periodontitis and Associated Systemic Diseases: Implications for Pathomechanisms and Therapeutic Strategies","volume":"25","author":"Deng","year":"2024","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.cden.2024.07.002_bib134","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1034\/j.1600-0757.2002.280108.x","article-title":"Treatment of periodontal disease in the immunodeficient patient","volume":"28","author":"Holmstrup","year":"2002","journal-title":"Periodontol 2000"},{"issue":"4","key":"10.1016\/j.cden.2024.07.002_bib135","first-page":"550","article-title":"Pocket oxygen tension in smokers and non-smokers with periodontal disease","volume":"71","author":"Hanioka","year":"2000","journal-title":"J\u00a0Periodontol"},{"issue":"2","key":"10.1016\/j.cden.2024.07.002_bib136","first-page":"196","article-title":"Cigarette smoking and the periodontal patient","volume":"75","author":"Johnson","year":"2004","journal-title":"J\u00a0Periodontol"}],"container-title":["Dental Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011853224000454?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011853224000454?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T10:36:34Z","timestamp":1725618994000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0011853224000454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":136,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S0011853224000454"],"URL":"https:\/\/doi.org\/10.1016\/j.cden.2024.07.002","relation":{},"ISSN":["0011-8532"],"issn-type":[{"value":"0011-8532","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systemic Factors Affecting Prognosis in Periodontics","name":"articletitle","label":"Article Title"},{"value":"Dental Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cden.2024.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}