{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T05:17:11Z","timestamp":1784351831624,"version":"3.55.0"},"reference-count":157,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32GM008433"],"award-info":[{"award-number":["T32GM008433"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32GM008169"],"award-info":[{"award-number":["T32GM008169"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U01CA250040"],"award-info":[{"award-number":["U01CA250040"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cells & Development"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.cdev.2022.203793","type":"journal-article","created":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T17:23:35Z","timestamp":1653845015000},"page":"203793","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Immune-mediated alopecias and their mechanobiological aspects"],"prefix":"10.1016","volume":"170","author":[{"given":"Valencia E.","family":"Watson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makala L.","family":"Faniel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nourine A.","family":"Kamili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loren D.","family":"Krueger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.cdev.2022.203793_bb0005","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1001\/jamadermatol.2020.1859","article-title":"Central centrifugal cicatricial alopecia","volume":"156","author":"Aguh","year":"2020","journal-title":"JAMA Dermatol"},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0010","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.jaad.2018.05.1257","article-title":"Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia","volume":"79","author":"Aguh","year":"2018","journal-title":"J. Am. Acad. Dermatol."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0015","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/imm.12791","article-title":"Regulatory T cells in skin","volume":"152","author":"Ali","year":"2017","journal-title":"Immunology"},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0020","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1242\/jcs.02793","article-title":"The hair cycle","volume":"119","author":"Alonso","year":"2006","journal-title":"J. Cell Sci."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0025","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/jid.2010.291","article-title":"Exploring the \u201chair growth-wound healing connection\u201d: anagen phase promotes wound re-epithelialization","volume":"131","author":"Ansell","year":"2011","journal-title":"J. Investig. Dermatol."},{"issue":"7","key":"10.1016\/j.cdev.2022.203793_bb0030","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/intimm\/dxz039","article-title":"Pathomechanisms of immune-mediated alopecia","volume":"31","author":"Anzai","year":"2019","journal-title":"Int. Immunol."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0035","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.cell.2015.08.021","article-title":"A distinct function of regulatory T cells in tissue protection","volume":"162","author":"Arpaia","year":"2015","journal-title":"Cell"},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0040","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/ijd.12808","article-title":"T-helper 17 cytokines (interleukins 17, 21, 22, and 6, and tumor necrosis factor-\u03b1) in patients with alopecia areata: association with clinical type and severity","volume":"55","author":"Atwa","year":"2016","journal-title":"Int. J. Dermatol."},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0045","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1159\/000485080","article-title":"Immune privilege collapse and alopecia development: is stress a factor","volume":"4","author":"Azzawi","year":"2018","journal-title":"Skin Appendage Disord."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0050","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/sj.jid.5700009","article-title":"Major histocompatibility complex class I chain-related gene a polymorphisms and extended haplotypes are associated with familial alopecia areata","volume":"126","author":"Barahmani","year":"2006","journal-title":"J. Investig. Dermatol."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0055","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1073\/pnas.1315606111","article-title":"CD28 and CD3 have complementary roles in T-cell traction forces","volume":"111","author":"Bashour","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4342","key":"10.1016\/j.cdev.2022.203793_bb0060","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1126\/science.347575","article-title":"Models for the specific adhesion of cells to cells","volume":"200","author":"Bell","year":"1978","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0094260","article-title":"Abnormal interactions between perifollicular mast cells and CD8+ T-cells may contribute to the pathogenesis of alopecia areata","volume":"9","author":"Bertolini","year":"2014","journal-title":"PLoS ONE"},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0070","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/exd.14155","article-title":"Hair follicle immune privilege and its collapse in alopecia areata","volume":"29","author":"Bertolini","year":"2020","journal-title":"Exp. Dermatol."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0075","doi-asserted-by":"crossref","DOI":"10.3109\/09546634.2015.1093591","article-title":"Serum cytokine and chemokine profiles in patients with alopecia areata","volume":"27","author":"Bilgic","year":"2016","journal-title":"J. Dermatol. Treat."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0080","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.jaad.2014.09.058","article-title":"Primary cicatricial alopecia: lymphocytic primary cicatricial alopecias, including chronic cutaneous lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, and Graham-little syndrome","volume":"75","author":"Bolduc","year":"2016","journal-title":"J. Am. Acad. Dermatol."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0085","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/exd.14073","article-title":"A \"hair-raising\" history of alopecia areata","volume":"29","author":"Broadley","year":"2020","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.cdev.2022.203793_bb0090","series-title":"Small Animal Dermatology Secrets","first-page":"1","article-title":"Structure and function of the skin","author":"Campbell","year":"2004"},{"key":"10.1016\/j.cdev.2022.203793_bb0095","doi-asserted-by":"crossref","first-page":"451","DOI":"10.3389\/fendo.2019.00451","article-title":"Type 2 diabetes: how much of an autoimmune Disease?","volume":"10","author":"de Candia","year":"2019","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0100","doi-asserted-by":"crossref","first-page":"151","DOI":"10.15252\/embj.201694902","article-title":"Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny","volume":"36","author":"Chac\u00f3n-Mart\u00ednez","year":"2017","journal-title":"EMBO J."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0105","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/imr.12122","article-title":"Mechanical regulation of T-cell functions","volume":"256","author":"Chen","year":"2013","journal-title":"Immunol. Rev."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0110","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1083\/jcb.201201091","article-title":"Observing force-regulated conformational changes and ligand dissociation from a single integrin on cells","volume":"199","author":"Chen","year":"2012","journal-title":"J. Cell Biol."},{"issue":"23","key":"10.1016\/j.cdev.2022.203793_bb0115","doi-asserted-by":"crossref","first-page":"3134","DOI":"10.1091\/mbc.e17-04-0228","article-title":"Receptor-mediated cell mechanosensing","volume":"28","author":"Chen","year":"2017","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.cdev.2022.203793_bb0120","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.matbio.2016.07.002","article-title":"Force regulated conformational change of integrin alphaVbeta3","volume":"60\u201361","author":"Chen","year":"2017","journal-title":"Matrix Biol."},{"key":"10.1016\/j.cdev.2022.203793_bb0125","doi-asserted-by":"crossref","first-page":"97","DOI":"10.32604\/mcb.2019.07123","article-title":"Fast force loading disrupts molecular bond stability in human and mouse cell adhesions","volume":"16","author":"Chen","year":"2019","journal-title":"Mol. Cell. Biomech."},{"key":"10.1016\/j.cdev.2022.203793_bb0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/320495","article-title":"The CD39-adenosinergic Axis in the pathogenesis of immune and nonimmune diabetes","volume":"2012","author":"Chia","year":"2012","journal-title":"J. Biomed. Biotechnol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4172\/2155-9554.1000138","article-title":"Detumescence therapy of human scalp for natural hair regrowth","volume":"3","author":"Choy","year":"2014","journal-title":"J. Clin. Exp. Dermatol. Res."},{"key":"10.1016\/j.cdev.2022.203793_bb0140","series-title":"The Autoimmune Diseases","first-page":"493","article-title":"Animal models of organ-specific autoimmune disease","author":"Coppieters","year":"2019"},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0150","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.tibs.2017.11.008","article-title":"TCR signaling: mechanisms of initiation and propagation","volume":"43","author":"Courtney","year":"2018","journal-title":"Trends Biochem. Sci."},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0155","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.4049\/jimmunol.1501798","article-title":"CXCR3 blockade inhibits T cell migration into the skin and prevents development of alopecia areata","volume":"197","author":"Dai","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.cdev.2022.203793_bb0160","series-title":"Science in Clothing Comfort","first-page":"31","article-title":"Neurophysiological processes in clothing comfort","author":"Das","year":"2010"},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0165","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1073\/pnas.1424829112","article-title":"Force-dependent transition in the T-cell receptor beta-subunit allosterically regulates peptide discrimination and pMHC bond lifetime","volume":"112","author":"Das","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"49","key":"10.1016\/j.cdev.2022.203793_bb0170","doi-asserted-by":"crossref","first-page":"25292","DOI":"10.1074\/jbc.M116.752865","article-title":"Pre-T cell receptors (Pre-TCRs) leverage vbeta complementarity determining regions (CDRs) and hydrophobic patch in mechanosensing thymic self-ligands","volume":"291","author":"Das","year":"2016","journal-title":"J. Biol. Chem."},{"issue":"1274","key":"10.1016\/j.cdev.2022.203793_bb0175","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1098\/rspb.1988.0038","article-title":"The reaction-limited kinetics of membrane-to-surface adhesion and detachment","volume":"234","author":"Dembo","year":"1988","journal-title":"Proc. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.cdev.2022.203793_bb0180","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1126\/science.1171643","article-title":"Growth factors, matrices, and forces combine and control stem cells","author":"Discher","year":"2009","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0185","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1016\/j.jisp.2017.01.004","article-title":"Central centrifugal cicatricial alopecia: new insights and a call for action","volume":"18","author":"Dlova","year":"2017","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0190","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/ncb3336","article-title":"Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity","volume":"18","author":"Elosegui-Artola","year":"2016","journal-title":"Nat. Cell Biol."},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0195","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.cell.2006.06.044","article-title":"Matrix elasticity directs stem cell lineage specification","volume":"126","author":"Engler","year":"2006","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0200","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2021107739","article-title":"NKG2D discriminates diverse ligands through selectively mechano-regulated ligand conformational changes","volume":"41","author":"Fan","year":"2022","journal-title":"EMBO J"},{"key":"10.1016\/j.cdev.2022.203793_bb0205","first-page":"321","article-title":"Cutaneous sensory systems","author":"Feher","year":"2012","journal-title":"Quantitative Human Physiology"},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0210","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.it.2018.05.005","article-title":"Alphabeta T cell receptor mechanosensing forces out serial engagement","volume":"39","author":"Feng","year":"2018","journal-title":"Trends Immunol."},{"issue":"39","key":"10.1016\/j.cdev.2022.203793_bb0215","doi-asserted-by":"crossref","first-page":"E8204","DOI":"10.1073\/pnas.1703559114","article-title":"Mechanosensing drives acuity of alphabeta T-cell recognition","volume":"114","author":"Feng","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cdev.2022.203793_bb0220","doi-asserted-by":"crossref","first-page":"4886","DOI":"10.1038\/ncomms5886","article-title":"Dynamic catch of a Thy-1\u2013\u03b15\u03b21+ syndecan-4 trimolecular complex","author":"Fiore","year":"2014","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0225","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/cup.13666","article-title":"Characterization of the inflammatory features of central centrifugal cicatricial alopecia","volume":"47","author":"Flamm","year":"2020","journal-title":"J. Cutan. Pathol."},{"issue":"11","key":"10.1016\/j.cdev.2022.203793_bb0230","doi-asserted-by":"crossref","first-page":"7602","DOI":"10.4049\/jimmunol.0901881","article-title":"CD39+Foxp3+ regulatory T cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis","volume":"183","author":"Fletcher","year":"2009","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0235","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1365-2133.2006.07377.x","article-title":"Interferon-\u03b3-deficient mice are resistant to the development of alopecia areata","volume":"155","author":"Freyschmidt-Paul","year":"2006","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.cdev.2022.203793_bb0240","series-title":"StatPearls","article-title":"Central centrifugal cicatricial alopecia","author":"Gabros","year":"2021"},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0245","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.0022-202X.2004.23599.x","article-title":"Organization of Stem Cells and Their Progeny in human epidermis","volume":"124","author":"Ghazizadeh","year":"2005","journal-title":"J. Investig. Dermatol."},{"issue":"16","key":"10.1016\/j.cdev.2022.203793_bb0250","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1056\/NEJMra1103442","article-title":"Alopecia areata","volume":"366","author":"Gilhar","year":"2012","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0255","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1038\/jidsymp.2013.11","article-title":"A new humanized mouse model for alopecia areata","volume":"16","author":"Gilhar","year":"2013","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0260","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1172\/JCI31942","article-title":"Lymphocytes, neuropeptides, and genes involved in alopecia areata","volume":"117","author":"Gilhar","year":"2007","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0265","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1365-2133.1992.tb07815.x","article-title":"Failure of passive transfer of serum from patients with alopecia areata and alopecia universalis to inhibit hair growth in transplants of human scalp skin grafted on to nude mice","volume":"126","author":"Gilhar","year":"1992","journal-title":"Br. J. Dermatol."},{"issue":"7","key":"10.1016\/j.cdev.2022.203793_bb0270","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.autrev.2016.03.008","article-title":"Alopecia areata: animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies","volume":"15","author":"Gilhar","year":"2016","journal-title":"Autoimmunol. Rev."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0275","doi-asserted-by":"crossref","first-page":"216","DOI":"10.4103\/ijt.ijt_11_19","article-title":"Central centrifugal cicatricial alopecia following a patchy pattern: a new form of clinical presentation and a challenging diagnosis for the dermatologist","volume":"11","author":"Gomez-Zubiaur","year":"2019","journal-title":"Int. J. Trichol."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0280","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/TP.0b013e3181e7e54f","article-title":"The role of the thymus in tolerance","volume":"90","author":"Griesemer","year":"2010","journal-title":"Transplantation"},{"issue":"12","key":"10.1016\/j.cdev.2022.203793_bb0285","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1586\/1744666X.2015.1085306","article-title":"The role of lymphocytes in the development and treatment of alopecia areata","volume":"11","author":"Guo","year":"2015","journal-title":"Expert. Rev. Clin. Immunol."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0290","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.0022-202X.2004.23237.x","article-title":"Burden of hair loss: stress and the underestimated psychosocial impact of telogen effluvium and androgenetic alopecia","volume":"123","author":"Hadshiew","year":"2004","journal-title":"J. Investig. Dermatol."},{"issue":"9","key":"10.1016\/j.cdev.2022.203793_bb0295","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0222473","article-title":"Correction: alopecia areata patients show deficiency of FOXP3+CD39+ T regulatory cells and clonotypic restriction of treg TCR\u03b2-chain, which highlights the immunopathological aspect of the disease","volume":"14","author":"Hamed","year":"2019","journal-title":"PLOS ONE"},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0300","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1111\/bjd.18854","article-title":"Profiling the human hair follicle immune system in lichen planopilaris and frontal fibrosing alopecia: can macrophage polarization differentiate these two conditions microscopically?","volume":"183","author":"Harries","year":"2020","journal-title":"Br. J. Dermatol."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0305","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/path.4233","article-title":"Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche","volume":"231","author":"Harries","year":"2013","journal-title":"J. Pathol."},{"issue":"6474","key":"10.1016\/j.cdev.2022.203793_bb0310","doi-asserted-by":"crossref","DOI":"10.1126\/science.aax9131","article-title":"Dermal sheath contraction powers stem cell niche relocation during hair cycle regression","volume":"367","author":"Heitman","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.cdev.2022.203793_bb0315","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2147\/CCID.S100816","article-title":"Central centrifugal cicatricial alopecia: challenges and solutions","volume":"9","author":"Herskovitz","year":"2016","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0320","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1038\/s41577-019-0162-3","article-title":"T cells and the skin: from protective immunity to inflammatory skin disorders","volume":"19","author":"Ho","year":"2019","journal-title":"Nat. Rev. Immunol."},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0325","doi-asserted-by":"crossref","first-page":"3557","DOI":"10.4049\/jimmunol.1501407","article-title":"Force-regulated in situ TCR-peptide-bound MHC class II kinetics determine functions of CD4+ T cells","volume":"195","author":"Hong","year":"2015","journal-title":"J. Immunol."},{"issue":"12","key":"10.1016\/j.cdev.2022.203793_bb0330","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1038\/s41590-018-0259-z","article-title":"A TCR mechanotransduction signaling loop induces negative selection in the thymus","volume":"19","author":"Hong","year":"2018","journal-title":"Nat. Immunol."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0335","doi-asserted-by":"crossref","first-page":"156","DOI":"10.5021\/ad.2017.29.2.156","article-title":"The contributory roles of Th17 lymphocyte and cytotoxic T lymphocyte at the hair bulge region as well as the hair bulb area in the chronic alopecia areata patients","volume":"29","author":"Hong","year":"2017","journal-title":"Ann. Dermatol."},{"issue":"9","key":"10.1016\/j.cdev.2022.203793_bb0340","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1084\/jem.190.9.1197","article-title":"Immune privilege","volume":"190","author":"Hong","year":"1999","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0345","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1087-0024.2004.00835.x","article-title":"Autoimmunity: alopecia areata","volume":"9","author":"Hordinsky","year":"2004","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0350","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.cell.2010.11.049","article-title":"Dynamics between stem cells, niche, and progeny in the hair follicle","volume":"144","author":"Hsu","year":"2011","journal-title":"Cell"},{"issue":"7290","key":"10.1016\/j.cdev.2022.203793_bb0355","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1038\/nature08944","article-title":"The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness","volume":"464","author":"Huang","year":"2010","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0360","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1080\/07853890310016333","article-title":"Mechanobiology and diseases of mechanotransduction","volume":"35","author":"Ingber","year":"2003","journal-title":"Ann. Med."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0365","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S0002-9440(10)63151-3","article-title":"Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model","volume":"164","author":"Ito","year":"2004","journal-title":"Am. J. Pathol."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0370","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1038\/sj.jid.5701183","article-title":"Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack","volume":"128","author":"Ito","year":"2008","journal-title":"J. Investig. Dermatol."},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0375","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1111\/exd.14129","article-title":"Understanding the significance of cytokines and chemokines in the pathogenesis of alopecia areata","volume":"29","author":"Ito","year":"2020","journal-title":"Exp. Dermatol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0380","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.alit.2019.07.009","article-title":"Plasmacytoid dendritic cells as a possible key player to initiate alopecia areata in the C3H\/HeJ mouse","volume":"69","author":"Ito","year":"2020","journal-title":"Allergol. Int."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0385","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/cup.13592","article-title":"Clinicopathologic and immunophenotypic characterization of lichen planopilaris and central centrifugal cicatricial alopecia: a comparative study of 51 cases","volume":"47","author":"Jordan","year":"2020","journal-title":"J. Cutan. Pathol."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0390","doi-asserted-by":"crossref","first-page":"L5","DOI":"10.1016\/j.bpj.2011.12.011","article-title":"Mechanosensing in T lymphocyte activation","volume":"102","author":"Judokusumo","year":"2012","journal-title":"Biophys. J."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0395","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1159\/000497392","article-title":"Are preferred scalp locations for alopecia areata patches a clue to neuronal Etiology?","volume":"5","author":"Juhasz","year":"2019","journal-title":"Skin Appendage Disorders"},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0400","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/sj.jid.5700655","article-title":"Clues from alopecia areata on the role of neuropeptides in the initiation of autoimmunity","volume":"127","author":"Kalish","year":"2007","journal-title":"J. Investig. Dermatol."},{"issue":"45","key":"10.1016\/j.cdev.2022.203793_bb0405","doi-asserted-by":"crossref","first-page":"31028","DOI":"10.1074\/jbc.M109.052712","article-title":"The alphabeta T cell receptor is an anisotropic mechanosensor","volume":"284","author":"Kim","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cdev.2022.203793_bb0410","doi-asserted-by":"crossref","first-page":"76","DOI":"10.3389\/fimmu.2012.00076","article-title":"TCR mechanobiology: torques and tunable structures linked to early T cell signaling","volume":"3","author":"Kim","year":"2012","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0415","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.molcel.2013.01.015","article-title":"Cyclic mechanical reinforcement of integrin-ligand interactions","volume":"49","author":"Kong","year":"2013","journal-title":"Mol. Cell"},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0420","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1182\/blood-2003-02-0449","article-title":"Hair follicles serve as local reservoirs of skin mast cell precursors","volume":"102","author":"Kumamoto","year":"2003","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0425","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1001\/archdermatol.2011.66","article-title":"Medical and environmental risk factors for the development of central centrifugal cicatricial alopecia: a population study","volume":"147","author":"Kyei","year":"2011","journal-title":"Arch. Dermatol."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109531","article-title":"Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation","volume":"36","author":"Lanz","year":"2021","journal-title":"Cell Rep."},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0435","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.216911","article-title":"Force-history dependence and cyclic mechanical reinforcement of actin filaments at the single molecular level","volume":"132","author":"Lee","year":"2019","journal-title":"J. Cell Sci."},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0440","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.jaad.2019.06.1300","article-title":"Racial characteristics of alopecia areata in the United States","volume":"83","author":"Lee","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.cdev.2022.203793_bb0445","series-title":"Minireviews of the Neurosciences from Life Sciences","first-page":"215","article-title":"Substance p","author":"Leeman","year":"1975"},{"issue":"12","key":"10.1016\/j.cdev.2022.203793_bb0450","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1038\/s41551-021-00826-6","article-title":"Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy","volume":"5","author":"Lei","year":"2021","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.cdev.2022.203793_bb0455","series-title":"Alopecia Areata","author":"Lepe","year":"2021"},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0460","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1038\/s41467-021-22965-9","article-title":"PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition","volume":"12","author":"Li","year":"2021","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0465","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1001\/jamadermatol.2018.5218","article-title":"Association of out-of-Pocket Health Care Costs and Financial Burden for patients with alopecia areata","volume":"155","author":"Li","year":"2019","journal-title":"JAMA Dermatol."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0470","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.cell.2014.02.053","article-title":"Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling","volume":"157","author":"Liu","year":"2014","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0475","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.jaad.2016.04.035","article-title":"Health-related quality of life (HRQoL) among patients with alopecia areata (AA): a systematic review","volume":"75","author":"Liu","year":"2016","journal-title":"J. Am. Acad. Dermatol."},{"issue":"20","key":"10.1016\/j.cdev.2022.203793_bb0480","doi-asserted-by":"crossref","first-page":"5610","DOI":"10.1073\/pnas.1600163113","article-title":"DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity","volume":"113","author":"Liu","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0485","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.cellimm.2011.06.010","article-title":"T-cell specific defect in expression of the NTPDase CD39 as a biomarker for lupus","volume":"271","author":"Loza","year":"2011","journal-title":"Cell. Immunol."},{"issue":"7","key":"10.1016\/j.cdev.2022.203793_bb0490","doi-asserted-by":"crossref","first-page":"4552","DOI":"10.1021\/acs.nanolett.6b01817","article-title":"Ratiometric tension probes for mapping receptor forces and clustering at intermembrane junctions","volume":"16","author":"Ma","year":"2016","journal-title":"Nano Lett."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0495","doi-asserted-by":"crossref","DOI":"10.3892\/etm.2017.4312","article-title":"Th1\/Th2 PB balance and CD200 expression of patients with active severe alopecia areata","volume":"13","author":"Ma","year":"2017","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.cdev.2022.203793_bb0500","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1242\/dev.024166","article-title":"Mechanical control of tissue and organ development","author":"Mammoto","year":"2010","journal-title":"Development"},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0505","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/S0021-9258(17)49904-2","article-title":"The structural basis of T-cell receptor (TCR) activation: an enduring enigma","volume":"295","author":"Mariuzza","year":"2020","journal-title":"J. Biol. Chem."},{"issue":"6936","key":"10.1016\/j.cdev.2022.203793_bb0510","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/nature01605","article-title":"Direct observation of catch bonds involving cell-adhesion molecules","volume":"423","author":"Marshall","year":"2003","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0515","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1529\/biophysj.104.050567","article-title":"Force history dependence of receptor-ligand dissociation","volume":"88","author":"Marshall","year":"2005","journal-title":"Biophys. J."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0520","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0036421","article-title":"Modulatory role of sensory innervation on hair follicle stem cell progeny during wound healing of the rat skin","volume":"7","author":"Mart\u00ednez-Mart\u00ednez","year":"2012","journal-title":"PLoS ONE"},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0525","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1046\/j.1523-1747.1998.00380.x","article-title":"Experimental induction of alopecia areata-like hair loss in C3H\/HeJ mice using full-thickness skin grafts","volume":"111","author":"McElwee","year":"1998","journal-title":"J. Investig. Dermatol."},{"issue":"9","key":"10.1016\/j.cdev.2022.203793_bb0530","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/exd.12209","article-title":"What causes alopecia areata?","volume":"22","author":"McElwee","year":"2013","journal-title":"Exp. Dermatol."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0535","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1038\/jid.2012.17","article-title":"Increased expression of Cxcr3 and its ligands, Cxcl9 and Cxcl10, during the development of alopecia areata in the mouse","volume":"132","author":"McPhee","year":"2012","journal-title":"J. Investig. Dermatol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0540","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nri2887","article-title":"Mechanisms for T cell receptor triggering","volume":"11","author":"van der Merwe","year":"2011","journal-title":"Nat. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0545","first-page":"1077","article-title":"Evidence that the bulge region is a site of relative immune privilege in human hair follicles","volume":"159","author":"Meyer","year":"2008","journal-title":"Br. J. Dermatol."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0550","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1365-2133.1991.tb06054.x","article-title":"The DEBR rat: an animal model of human alopecia areata","volume":"125","author":"Michie","year":"1991","journal-title":"Br. J. Dermatol."},{"issue":"7","key":"10.1016\/j.cdev.2022.203793_bb0555","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1097\/DAD.0000000000001349","article-title":"Adipose infiltration of the dermis, involving the arrector pili muscle, and dermal displacement of eccrine sweat coils: new histologic observations in frontal fibrosing alopecia","volume":"41","author":"Miteva","year":"2019","journal-title":"Am. J. Dermatopathol."},{"issue":"10","key":"10.1016\/j.cdev.2022.203793_bb0560","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/j.0303-6987.2005.00399.x","article-title":"Possible role of the bulge region in the pathogenesis of inflammatory scarring alopecia: lichen planopilaris as the prototype","volume":"32","author":"Mobini","year":"2005","journal-title":"J. Cutan. Pathol."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0565","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s00403-016-1652-9","article-title":"ULBP3: a marker for alopecia areata incognita","volume":"308","author":"Moftah","year":"2016","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.cdev.2022.203793_bb0570","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2020.597661","article-title":"Stem cell mechanobiology and the role of biomaterials in governing mechanotransduction and matrix production for tissue regeneration","volume":"8","author":"Naqvi","year":"2020","journal-title":"Frontiers in bioengineering and biotechnology"},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0575","article-title":"Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration","volume":"8","author":"Nordenfelt","year":"2017","journal-title":"NatureCommunications"},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0580","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1067\/mjd.2003.68","article-title":"Summary of north american hair research society (NAHRS)-sponsored workshop on cicatricial alopecia, Duke University medical center, february 10 and 11, 2001","volume":"48","author":"Olsen","year":"2003","journal-title":"J. Am. Acad. Dermatol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0585","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s10792-021-01991-y","article-title":"The ocular surface findings in alopecia areata patients: clinical parameters and impression cytology","volume":"42","author":"Oltulu","year":"2022","journal-title":"Int. Ophthalmol."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0590","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.ccr.2005.08.010","article-title":"Tensional homeostasis and the malignant phenotype","volume":"8","author":"Paszek","year":"2005","journal-title":"Cancer Cell"},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0595","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1038\/jidsymp.2013.7","article-title":"The role of hair follicle immune privilege collapse in alopecia areata: status and perspectives","volume":"16","author":"Paus","year":"2013","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0600","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1016\/j.jisp.2017.10.014","article-title":"Hair follicle immune privilege revisited: the key to alopecia areata management","volume":"19","author":"Paus","year":"2018","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"issue":"10","key":"10.1016\/j.cdev.2022.203793_bb0605","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.molmed.2014.06.002","article-title":"Neuroendocrinology of the hair follicle: principles and clinical perspectives","volume":"20","author":"Paus","year":"2014","journal-title":"Trends Mol. Med."},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0610","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1073\/pnas.1424792112","article-title":"Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis","volume":"112","author":"Peres","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0615","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/JID.2015.402","article-title":"Functional interpretation of genome-wide association study evidence in alopecia areata","volume":"136","author":"Petukhova","year":"2016","journal-title":"J. Investig. Dermatol."},{"issue":"7302","key":"10.1016\/j.cdev.2022.203793_bb0620","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/nature09114","article-title":"Genome-wide association study in alopecia areata implicates both innate and adaptive immunity","volume":"466","author":"Petukhova","year":"2010","journal-title":"Nature"},{"issue":"9","key":"10.1016\/j.cdev.2022.203793_bb0625","first-page":"800","article-title":"The arrector pili muscle and the follicular unit of the scalp: a microscopic anatomy study","volume":"28","author":"Poblet","year":"2002","journal-title":"Dermatol. Surg."},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0630","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1365-4632.2006.02507.x","article-title":"Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathological study","volume":"45","author":"Poblet","year":"2006","journal-title":"Int. J. Dermatol."},{"key":"10.1016\/j.cdev.2022.203793_bb0635","series-title":"Nature Reviews. Disease Primers","article-title":"Alopecia areata","volume":"3","author":"Pratt","year":"2017"},{"key":"10.1016\/j.cdev.2022.203793_bb0640","article-title":"Differentiation of frontal fibrosing alopecia and lichen planopilaris on trichoscopy: a comprehensive review","author":"Rajan","year":"2021","journal-title":"J. Cosmet. Dermatol."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0645","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1111\/j.0022-202X.2004.23461.x","article-title":"Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance?","volume":"123","author":"Rosenblum","year":"2004","journal-title":"J.Investig. Dermatol."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0650","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jdermsci.2005.11.003","article-title":"CD200, a \"no danger\" signal for hair follicles","volume":"41","author":"Rosenblum","year":"2006","journal-title":"J. Dermatol. Sci."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0655","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1111\/jdv.15327","article-title":"HrQoL in hair loss-affected patients with alopecia areata, androgenetic alopecia and telogen effluvium: the role of personality traits and psychosocial anxiety","volume":"33","author":"Russo","year":"2019","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"37","key":"10.1016\/j.cdev.2022.203793_bb0660","doi-asserted-by":"crossref","first-page":"32749","DOI":"10.1074\/jbc.M111.240044","article-title":"Regulation of catch bonds by rate of force application","volume":"286","author":"Sarangapani","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0665","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.cell.2018.06.017","article-title":"Isolation of a structural mechanism for uncoupling T cell receptor signaling from peptide-MHC binding","volume":"174","author":"Sibener","year":"2018","journal-title":"Cell"},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0670","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1038\/sj.jid.5700704","article-title":"Substance P as an immunomodulatory neuropeptide in a mouse model for autoimmune hair loss (Alopecia Areata)","volume":"127","author":"Siebenhaar","year":"2007","journal-title":"J. Investig. Dermatol."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0675","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/1523-1747.ep12477885","article-title":"Angiogenic activity is defective in monocytes from patients with alopecia universalis","volume":"95","author":"Skoutelis","year":"1990","journal-title":"J. Investig. Dermatol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0680","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2017.04.1141","article-title":"Alopecia areata: disease characteristics, clinical evaluation, and new perspectives on pathogenesis","volume":"78","author":"Strazzulla","year":"2018","journal-title":"J. Am. Acad. Dermatol."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0685","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.jaci.2015.06.032","article-title":"Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17\/TH22 skewing","volume":"136","author":"Su\u00e1rez-Fari\u00f1as","year":"2015","journal-title":"J. Allergy Clin. Immunol."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0690","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/exd.13664","article-title":"A proposed mechanism for central centrifugal cicatricial alopecia","volume":"29","author":"Subash","year":"2020","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.cdev.2022.203793_bb0695","doi-asserted-by":"crossref","first-page":"299","DOI":"10.2147\/ITT.S266409","article-title":"Alopecia areata: an autoimmune disease of multiple players","volume":"10","author":"Suchonwanit","year":"2021","journal-title":"ImmunoTargets Ther."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0700","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1007\/s40257-021-00630-7","article-title":"A practical approach to the diagnosis and management of classic lichen planopilaris","volume":"22","author":"Svigos","year":"2021","journal-title":"Am. J. Clin. Dermatol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0705","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1365-2133.2008.08861.x","article-title":"Frontal fibrosing alopecia: clinical presentations and prognosis","volume":"160","author":"Tan","year":"2009","journal-title":"Br. J. Dermatol."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0710","doi-asserted-by":"crossref","DOI":"10.4103\/0019-5154.41650","article-title":"Alopecia areata and autoimmunity: a clinical study","volume":"53","author":"Thomas","year":"2008","journal-title":"Indian J. Dermatol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0715","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1016\/j.jisp.2017.10.007","article-title":"Race and alopecia areata amongst US women","volume":"19","author":"Thompson","year":"2018","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"issue":"2","key":"10.1016\/j.cdev.2022.203793_bb0720","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1046\/j.1087-0024.2003.00805.x","article-title":"Characterization of hair follicle antigens targeted by the anti-hair follicle immune response","volume":"8","author":"Tobin","year":"2003","journal-title":"J. Investig. Dermatol. Symp. Proc."},{"issue":"6","key":"10.1016\/j.cdev.2022.203793_bb0725","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1111\/bjd.12921","article-title":"Destruction of the arrector pili muscle and fat infiltration in androgenic alopecia","volume":"170","author":"Torkamani","year":"2014","journal-title":"Br. J. Dermatol."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0730","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/1523-1747.ep12355013","article-title":"Retinal pigment epithelium function in alopecia areata","volume":"86","author":"Tosti","year":"1986","journal-title":"J. Investig. Dermatol."},{"issue":"8","key":"10.1016\/j.cdev.2022.203793_bb0735","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1016\/j.jid.2016.04.004","article-title":"Identification of autoantigen epitopes in Alopecia areata","volume":"136","author":"Wang","year":"2016","journal-title":"J. Investig. Dermatol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0740","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1600-065X.2012.01161.x","article-title":"The structural basis of \u03b1\u03b2 T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function","volume":"250","author":"Wang","year":"2012","journal-title":"Immunol. Rev."},{"issue":"3","key":"10.1016\/j.cdev.2022.203793_bb0745","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.jaad.2008.09.049","article-title":"Increased history of childhood and lifetime traumatic events among adults with alopecia areata","volume":"60","author":"Willemsen","year":"2009","journal-title":"J. Am. Acad. Dermatol."},{"issue":"5","key":"10.1016\/j.cdev.2022.203793_bb0750","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.molcel.2018.12.018","article-title":"Mechano-regulation of peptide-MHC class I conformations determines TCR antigen recognition","volume":"73","author":"Wu","year":"2019","journal-title":"Mol. Cell"},{"issue":"9","key":"10.1016\/j.cdev.2022.203793_bb0755","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/nm.3645","article-title":"Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition","volume":"20","author":"Xing","year":"2014","journal-title":"Nat. Med."},{"issue":"9","key":"10.1016\/j.cdev.2022.203793_bb0760","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1001\/jamadermatol.2014.62","article-title":"Diagnostic usefulness of a peribulbar eosinophilic infiltrate in alopecia areata","volume":"150","author":"Yoon","year":"2014","journal-title":"JAMA Dermatol."},{"issue":"51","key":"10.1016\/j.cdev.2022.203793_bb0765","doi-asserted-by":"crossref","first-page":"42207","DOI":"10.1074\/jbc.M510407200","article-title":"Two-dimensional kinetics regulation of alphaLbeta2-ICAM-1 interaction by conformational changes of the alphaL-inserted domain","volume":"280","author":"Zhang","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.cdev.2022.203793_bb0770","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00403-015-1539-1","article-title":"Lesional infiltration of mast cells, langerhans cells, T cells and local cytokine profiles in alopecia areata","volume":"307","author":"Zhang","year":"2015","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.cdev.2022.203793_bb0775","series-title":"Cell Mechanics: Mechanical Response, Cell Adhesion, and Molecular Deformation","author":"Zhu","year":"2000"},{"key":"10.1016\/j.cdev.2022.203793_bb0780","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.cbpa.2019.08.005","article-title":"Dynamic bonds and their roles in mechanosensing","volume":"53","author":"Zhu","year":"2019","journal-title":"Curr. Opin. Chem. Biol."},{"issue":"1","key":"10.1016\/j.cdev.2022.203793_bb0785","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/imr.12016","article-title":"Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network","volume":"251","author":"Zhu","year":"2013","journal-title":"Immunol. Rev."},{"issue":"10","key":"10.1016\/j.cdev.2022.203793_bb0790","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1038\/s41590-019-0491-1","article-title":"Mechanosensing through immunoreceptors","volume":"20","author":"Zhu","year":"2019","journal-title":"Nat. Immunol."}],"container-title":["Cells & Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667290122000298?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667290122000298?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T11:27:14Z","timestamp":1778930834000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667290122000298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":157,"alternative-id":["S2667290122000298"],"URL":"https:\/\/doi.org\/10.1016\/j.cdev.2022.203793","relation":{},"ISSN":["2667-2901"],"issn-type":[{"value":"2667-2901","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immune-mediated alopecias and their mechanobiological aspects","name":"articletitle","label":"Article Title"},{"value":"Cells & Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cdev.2022.203793","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"203793"}}