{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:23:43Z","timestamp":1789647823342,"version":"4.0.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2104429"],"award-info":[{"award-number":["2104429"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cells &amp; Development"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.cdev.2024.203989","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T12:13:20Z","timestamp":1734610400000},"page":"203989","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Transitions between cooperative and crowding-dominated collective motion in non-jammed MDCK monolayers"],"prefix":"10.1016","volume":"181","author":[{"given":"Steven J.","family":"Chisolm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vignesh","family":"Subramaniam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle D.","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas E.","family":"Angelini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cdev.2024.203989_bb0005","doi-asserted-by":"crossref","first-page":"4714","DOI":"10.1073\/pnas.1010059108","article-title":"Glass-like dynamics of collective cell migration","volume":"108","author":"Angelini","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cdev.2024.203989_bb0010","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1038\/nphys3471","article-title":"A density-independent rigidity transition in biological tissues","volume":"11","author":"Bi","year":"2015","journal-title":"Nat. Phys."},{"key":"10.1016\/j.cdev.2024.203989_bb0015","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1039\/c3sm52893f","article-title":"Energy barriers and cell migration in densely packed tissues","volume":"10","author":"Bi","year":"2014","journal-title":"Soft Matter"},{"key":"10.1016\/j.cdev.2024.203989_bb0020","article-title":"Motility-driven glass and jamming transitions in biological tissues","volume":"6","author":"Bi","year":"2016","journal-title":"Phys. Rev. X"},{"key":"10.1016\/j.cdev.2024.203989_bb0025","doi-asserted-by":"crossref","unstructured":"Discher, D. E., Janmey, P. & Wang, Y.-l. Tissue cells feel and respond to the stiffness of their substrate. Science 310, 1139\u20131143 (2005).","DOI":"10.1126\/science.1116995"},{"key":"10.1016\/j.cdev.2024.203989_bb0030","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1016\/j.cub.2007.11.049","article-title":"The influence of cell mechanics, cell-cell interactions, and proliferation on epithelial packing","volume":"17","author":"Farhadifar","year":"2007","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cdev.2024.203989_bb0035","doi-asserted-by":"crossref","first-page":"3796","DOI":"10.1529\/biophysj.105.072215","article-title":"A master relation defines the nonlinear viscoelasticity of single fibroblasts","volume":"90","author":"Fern\u00e1ndez","year":"2006","journal-title":"Biophys. J."},{"key":"10.1016\/j.cdev.2024.203989_bb0040","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/nrm2720","article-title":"Collective cell migration in morphogenesis, regeneration and cancer","volume":"10","author":"Friedl","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.cdev.2024.203989_bb0045","doi-asserted-by":"crossref","first-page":"15314","DOI":"10.1073\/pnas.1510973112","article-title":"Physics of active jamming during collective cellular motion in a monolayer","volume":"112","author":"Garcia","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cdev.2024.203989_bb0050","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1073\/pnas.0504777103","article-title":"Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells","volume":"103","author":"Gardel","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cdev.2024.203989_bb0055","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1016\/j.bbagen.2014.03.020","article-title":"Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement","volume":"1840","author":"Haeger","year":"2014","journal-title":"Biochimica et Biophysica Acta (BBA)-General Subjects"},{"key":"10.1016\/j.cdev.2024.203989_bb0060","article-title":"Active jamming: self-propelled soft particles at high density. Physical review E\u2014statistical, nonlinear, and soft matter","volume":"84","author":"Henkes","year":"2011","journal-title":"Physics"},{"key":"10.1016\/j.cdev.2024.203989_bb0065","doi-asserted-by":"crossref","first-page":"4326","DOI":"10.1016\/j.bpj.2009.02.035","article-title":"Filamin a is essential for active cell stiffening but not passive stiffening under external force","volume":"96","author":"Kasza","year":"2009","journal-title":"Biophys. J."},{"key":"10.1016\/j.cdev.2024.203989_bb0070","doi-asserted-by":"crossref","first-page":"6148","DOI":"10.1038\/s41467-020-19904-5","article-title":"Gap junctions amplify spatial variations in cell volume in proliferating tumor spheroids","volume":"11","author":"McEvoy","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cdev.2024.203989_bb0075","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1242\/jcs.114.10.1829","article-title":"Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites","volume":"114","author":"Nakagawa","year":"2001","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cdev.2024.203989_bb0080","doi-asserted-by":"crossref","DOI":"10.1088\/1367-2630\/14\/11\/115012","article-title":"The impact of jamming on boundaries of collectively moving weak-interacting cells","volume":"14","author":"Nnetu","year":"2012","journal-title":"New J. Phys."},{"key":"10.1016\/j.cdev.2024.203989_bb0085","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1038\/nmat4357","article-title":"Unjamming and cell shape in the asthmatic airway epithelium","volume":"14","author":"Park","year":"2015","journal-title":"Nat. Mater."},{"key":"10.1016\/j.cdev.2024.203989_bb0090","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.diff.2013.02.005","article-title":"Collective migration and cell jamming","volume":"86","author":"Sadati","year":"2013","journal-title":"Differentiation"},{"key":"10.1016\/j.cdev.2024.203989_bb0095","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jbiomech.2017.01.016","article-title":"Elastic modulus and hydraulic permeability of MDCK monolayers","volume":"53","author":"Schulze","year":"2017","journal-title":"J. Biomech."},{"key":"10.1016\/j.cdev.2024.203989_bb0100","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/s41592-020-01018-x","article-title":"Cellpose: a generalist algorithm for cellular segmentation","volume":"18","author":"Stringer","year":"2021","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cdev.2024.203989_bb0105","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/nmat3025","article-title":"Collective cell guidance by cooperative intercellular forces","volume":"10","author":"Tambe","year":"2011","journal-title":"Nat. Mater."},{"key":"10.1016\/j.cdev.2024.203989_bb0110","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/nrc822","article-title":"Epithelial\u2013mesenchymal transitions in tumour progression","volume":"2","author":"Thiery","year":"2002","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.cdev.2024.203989_bb0115","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/nphys1269","article-title":"Physical forces during collective cell migration","volume":"5","author":"Trepat","year":"2009","journal-title":"Nat. Phys."},{"key":"10.1016\/j.cdev.2024.203989_bb0120","doi-asserted-by":"crossref","first-page":"3393","DOI":"10.1002\/j.1460-2075.1985.tb04095.x","article-title":"Identification of a putative cell adhesion domain of uvomorulin","volume":"4","author":"Vestweber","year":"1985","journal-title":"EMBO J."},{"key":"10.1016\/j.cdev.2024.203989_bb0125","first-page":"C606","article-title":"Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells. American journal of physiology-cell","volume":"282","author":"Wang","year":"2002","journal-title":"Physiology"},{"key":"10.1016\/j.cdev.2024.203989_bb0130","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.bpj.2014.11.1856","article-title":"Cell volume fluctuations in MDCK monolayers","volume":"108","author":"Zehnder","year":"2015","journal-title":"Biophys. J."},{"key":"10.1016\/j.cdev.2024.203989_bb0135","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/j.jbiomech.2015.12.051","article-title":"A Langevin model of physical forces in cell volume fluctuations","volume":"49","author":"Zehnder","year":"2016","journal-title":"J. Biomech."},{"key":"10.1016\/j.cdev.2024.203989_bb0140","doi-asserted-by":"crossref","DOI":"10.1103\/PhysRevE.92.032729","article-title":"Multicellular density fluctuations in epithelial monolayers","volume":"92","author":"Zehnder","year":"2015","journal-title":"Phys. Rev. E"}],"container-title":["Cells &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667290124000998?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667290124000998?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T07:51:40Z","timestamp":1772351500000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667290124000998"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":28,"alternative-id":["S2667290124000998"],"URL":"https:\/\/doi.org\/10.1016\/j.cdev.2024.203989","relation":{},"ISSN":["2667-2901"],"issn-type":[{"value":"2667-2901","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transitions between cooperative and crowding-dominated collective motion in non-jammed MDCK monolayers","name":"articletitle","label":"Article Title"},{"value":"Cells & Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cdev.2024.203989","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"203989"}}