{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T12:12:46Z","timestamp":1778933566044,"version":"3.51.4"},"reference-count":93,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001688","name":"International Centre for Genetic Engineering and Biotechnology","doi-asserted-by":"publisher","award":["MEX21-04_EC"],"award-info":[{"award-number":["MEX21-04_EC"]}],"id":[{"id":"10.13039\/501100001688","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005739","name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","doi-asserted-by":"publisher","award":["CRP\/MEX21-04_EC"],"award-info":[{"award-number":["CRP\/MEX21-04_EC"]}],"id":[{"id":"10.13039\/501100005739","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006087","name":"National Autonomous University of Mexico Directorate General of Academic Staff Affairs","doi-asserted-by":"publisher","award":["IA202923"],"award-info":[{"award-number":["IA202923"]}],"id":[{"id":"10.13039\/501100006087","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007675","name":"International Center for Genetic Engineering and Biotechnology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007675","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Secretar\u00eda de Ciencia, Humanidades, Tecnolog\u00eda e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["1099237"],"award-info":[{"award-number":["1099237"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cells &amp; Development"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.cdev.2025.203998","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T05:10:27Z","timestamp":1738041027000},"page":"203998","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["A tale of two tissues: Patterning of the epidermis through morphogens and their role in establishing tracheal system organization"],"prefix":"10.1016","volume":"184","author":[{"given":"L.E.","family":"S\u00e1nchez-Cisneros","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.F.","family":"Frutis-Osorio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.D.","family":"R\u00edos-Barrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cdev.2025.203998_bb0005","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1242\/dev.120.11.3105","article-title":"Multiple requirements for the receptor serine\/threonine kinase thick veins reveal novel functions of TGF\u03b2 homologs during Drosophila embryogenesis","volume":"120","author":"Affolter","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0010","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/nature01822","article-title":"The molecular nature of the zebrafish tail organizer","volume":"424","author":"Agathon","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.cdev.2025.203998_bb0015","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1242\/jcs.085613","article-title":"Sequoia establishes tip-cell number in Drosophila trachea by regulating FGF levels","volume":"124","author":"Ara\u00fajo","year":"2011","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cdev.2025.203998_bb0020","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.1016\/j.celrep.2019.11.038","article-title":"Drosophila neuroblast selection is gated by notch, snail, SoxB, and EMT gene interplay","volume":"29","author":"Arefin","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.cdev.2025.203998_bb0025","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.1242\/dev.125.17.3521","article-title":"Induction of primitive streak and Hensen\u2019s node by the posterior marginal zone in the early chick embryo","volume":"125","author":"Bachvarova","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0030","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.devcel.2023.05.005","article-title":"Myosin waves and a mechanical asymmetry guide the oscillatory migration of Drosophila cardiac progenitors","volume":"58","author":"Balaghi","year":"2023","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0035","series-title":"Crosstalk between Basal Extracellular Matrix Adhesion and Building of Apical Architecture during Morphogenesis","first-page":"10","author":"Barrera-Vel\u00e1zquez","year":"2021"},{"key":"10.1016\/j.cdev.2025.203998_bb0040","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1242\/dev.120.3.613","article-title":"Induction of a second neural axis by the mouse node","volume":"120","author":"Beddington","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0045","first-page":"471","article-title":"Roles of wingless in patterning the larval epidermis of Drosophila","volume":"113","author":"Bejsovec","year":"1991","journal-title":"Dev. Camb. Engl."},{"key":"10.1016\/j.cdev.2025.203998_bb0050","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/s41592-023-01822-1","article-title":"High-resolution line-scan Brillouin microscopy for live imaging of mechanical properties during embryo development","volume":"20","author":"Bevilacqua","year":"2023","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cdev.2025.203998_bb0055","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1101\/gad.375706","article-title":"The RhoGAP crossveinless-c links trachealess and EGFR signaling to cell shape remodeling in Drosophila tracheal invagination","volume":"20","author":"Brodu","year":"2006","journal-title":"Genes Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0060","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/S0960-9822(01)00524-3","article-title":"Identification of the first invertebrate interleukin JAK\/STAT receptor, the Drosophila gene domeless","volume":"11","author":"Brown","year":"2001","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0092682","article-title":"Hedgehog is a positive regulator of FGF Signalling during embryonic tracheal cell migration","volume":"9","author":"But\u00ed","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.cdev.2025.203998_bb0070","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.259590","article-title":"Tracheal tube fusion in Drosophila involves release of extracellular vesicles from multivesicular bodies","volume":"135","author":"Camelo","year":"2022","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cdev.2025.203998_bb0075","series-title":"The Embryonic Development of Drosophila melanogaster","author":"Campos-Ortega","year":"2013"},{"key":"10.1016\/j.cdev.2025.203998_bb0080","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1242\/dev.087874","article-title":"The ETS domain transcriptional repressor anterior open inhibits MAP kinase and wingless signaling to couple tracheal cell fate with branch identity","volume":"140","author":"Caviglia","year":"2013","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0085","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1242\/dev.02482","article-title":"Egfr is essential for maintaining epithelial integrity during tracheal remodelling in Drosophila","volume":"133","author":"Cela","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0090","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.gep.2014.05.004","article-title":"Gene expression profiling of Drosophila tracheal fusion cells","volume":"15","author":"Chandran","year":"2014","journal-title":"Gene Expr. Patterns GEP"},{"key":"10.1016\/j.cdev.2025.203998_bb0095","doi-asserted-by":"crossref","first-page":"4959","DOI":"10.1242\/dev.125.24.4959","article-title":"The transcription factors KNIRPS and KNIRPS RELATED control cell migration and branch morphogenesis during Drosophila tracheal development","volume":"125","author":"Chen","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0100","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1242\/dev.127.20.4433","article-title":"Control of tracheal tubulogenesis by wingless signaling","volume":"127","author":"Chihara","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0105","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/363549a0","article-title":"Intercellular signalling in Drosophila segment formation reconstructed in vitro","volume":"363","author":"Cumberledge","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.cdev.2025.203998_bb0110","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/383332a0","article-title":"Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development","volume":"383","author":"Danielian","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.cdev.2025.203998_bb0115","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.mod.2009.08.004","article-title":"Spemann\u2019s organizer and the self-regulation of embryonic fields","volume":"126","author":"De Robertis","year":"2009","journal-title":"Mech. Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0120","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.devcel.2018.06.006","article-title":"Apical and basal matrix remodeling control epithelial morphogenesis","volume":"46","author":"Diaz-de-la-Loza","year":"2018","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0125","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/0959-437X(94)90068-E","article-title":"The making of a maggot: patterning the Drosophila embryonic epidermis","volume":"4","author":"DiNardo","year":"1994","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0130","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1006\/dbio.2002.0836","article-title":"Stripe provides cues synergizing with branchless to direct tracheal cell migration","volume":"252","author":"Dorfman","year":"2002","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0135","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/360347a0","article-title":"Drosophila wingless generates cell type diversity among engrailed expressing cells","volume":"360","author":"Dougan","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.cdev.2025.203998_bb0140","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0092-8674(92)90514-D","article-title":"Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo","volume":"71","author":"Ferguson","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0145","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1006\/dbio.1996.0125","article-title":"Development of the indirect flight muscle attachment sites inDrosophila: role of the PS Integrins and thestripeGene","volume":"176","author":"Fernandes","year":"1996","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0150","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.mod.2007.09.002","article-title":"Dpp signalling orchestrates dorsal closure by regulating cell shape changes both in the amnioserosa and in the epidermis","volume":"124","author":"Fern\u00e1ndez","year":"2007","journal-title":"Mech. Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0155","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1006\/dbio.2002.0799","article-title":"Spalt-induced specification of distinct dorsal and ventral domains is required for Drosophila tracheal patterning","volume":"250","author":"Franch-Marro","year":"2002","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0160","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1242\/dev.059188","article-title":"The Drosophila homologue of SRF acts as a boosting mechanism to sustain FGF-induced terminal branching in the tracheal system","volume":"138","author":"Gervais","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0165","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ydbio.2011.11.018","article-title":"The making of a fusion branch in the Drosophila trachea","volume":"362","author":"Gervais","year":"2012","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0170","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1101\/gad.5.4.697","article-title":"The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension","volume":"5","author":"Glazer","year":"1991","journal-title":"Genes Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0175","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1242\/dev.128.9.1599","article-title":"Hedgehog signaling patterns the tracheal branches","volume":"128","author":"Glazer","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0180","article-title":"Highly dynamic mechanical transitions in embryonic cell populations during Drosophila gastrulation","author":"Gomez","year":"2024","journal-title":"bioRxiv"},{"key":"10.1016\/j.cdev.2025.203998_bb0185","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/s41578-019-0169-1","article-title":"The stiffness of living tissues and its implications for tissue engineering","volume":"5","author":"Guimar\u00e3es","year":"2020","journal-title":"Nat. Rev. Mater."},{"key":"10.1016\/j.cdev.2025.203998_bb0190","doi-asserted-by":"crossref","first-page":"15712","DOI":"10.1073\/pnas.1914167117","article-title":"Hedgehog\u2013FGF signaling axis patterns anterior mesoderm during gastrulation","volume":"117","author":"Guzzetta","year":"2020","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cdev.2025.203998_bb0195","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.mod.2016.12.005","article-title":"Drosophila dorsal closure: an orchestra of forces to zip shut the embryo","volume":"144","author":"Hayes","year":"2017","journal-title":"Mech. Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0200","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/0092-8674(91)90263-X","article-title":"The choice of cell fate in the epidermis of Drosophila","volume":"64","author":"Heitzler","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0205","first-page":"427","article-title":"JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis","volume":"235","author":"Homsy","year":"2006","journal-title":"Dev. Dyn. Off. Publ. Am. Assoc. Anat."},{"key":"10.1016\/j.cdev.2025.203998_bb0210","series-title":"Current Topics in Developmental Biology","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/bs.ctdb.2022.02.004","article-title":"Chapter eight - innervation in organogenesis","author":"Honeycutt","year":"2022"},{"key":"10.1016\/j.cdev.2025.203998_bb0215","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1242\/dev.109.4.875","article-title":"The notch locus of Drosophila is required in epidermal cells for epidermal development","volume":"109","author":"Hoppe","year":"1990","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0220","doi-asserted-by":"crossref","first-page":"7150","DOI":"10.1038\/s41467-021-27384-4","article-title":"Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury","volume":"12","author":"Hu","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cdev.2025.203998_bb0225","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/366560a0","article-title":"Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo","volume":"366","author":"Ingham","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.cdev.2025.203998_bb0230","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1242\/dev.117.1.283","article-title":"Regulation of wingless transcription in the Drososphila embryo","volume":"117","author":"Ingham","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0235","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1101\/gad.1.8.868","article-title":"The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo","volume":"1","author":"Irish","year":"1987","journal-title":"Genes Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0240","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1101\/gad.10.1.103","article-title":"Tubulogenesis in Drosophila: A requirement for the trachealess gene product","volume":"10","author":"Isaac","year":"1996","journal-title":"Genes Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0245","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1038\/s41467-018-04754-z","article-title":"Guided morphogenesis through optogenetic activation of rho signalling during early Drosophila embryogenesis","volume":"9","author":"Izquierdo","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cdev.2025.203998_bb0250","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S1534-5807(01)00045-4","article-title":"The genomic response of the Drosophila embryo to JNK signaling","volume":"1","author":"Jasper","year":"2001","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0255","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/ncb882","article-title":"Planar polarity and actin dynamics in the epidermis of Drosophila","volume":"4","author":"Kaltschmidt","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0260","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.devcel.2022.03.007","article-title":"Condensation of the Drosophila nerve cord is oscillatory and depends on coordinated mechanical interactions","volume":"57","author":"Karkali","year":"2022","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0265","doi-asserted-by":"crossref","first-page":"5253","DOI":"10.1242\/dev.01404","article-title":"Hedgehog and decapentaplegic instruct polarized growth of cell extensions in the Drosophila trachea","volume":"131","author":"Kato","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0270","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1242\/dev.113.4.1495","article-title":"Hensen\u2019s node induces neural tissue in Xenopus ectoderm. Implications for the action of the organizer in neural induction","volume":"113","author":"Kintner","year":"1991","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0275","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.45145","article-title":"Two-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea","volume":"8","author":"Kondo","year":"2019","journal-title":"eLife"},{"key":"10.1016\/j.cdev.2025.203998_bb0280","doi-asserted-by":"crossref","first-page":"4095","DOI":"10.1242\/dev.122.12.4095","article-title":"Compartments, wingless and engrailed: patterning the ventral epidermis of Drosophila embryos","volume":"122","author":"Lawrence","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0285","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0092-8674(00)81297-0","article-title":"Morphogens, compartments, and pattern: lessons from Drosophila?","volume":"85","author":"Lawrence","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0290","first-page":"768","article-title":"Hedgehog signaling is essential for normal wound healing. Wound repair Regen. Off. Publ. Wound heal","volume":"16","author":"Le","year":"2008","journal-title":"Soc. Eur. Tissue Repair Soc."},{"key":"10.1016\/j.cdev.2025.203998_bb0295","first-page":"465","article-title":"Specification of leading and trailing cell features during collective migration in the Drosophila trachea","volume":"127","author":"Lebreton","year":"2014","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cdev.2025.203998_bb0300","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1101\/gad.10.22.2912","article-title":"Regulated breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system","volume":"10","author":"Lee","year":"1996","journal-title":"Genes Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0305","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000057","article-title":"A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo","volume":"17","author":"Lemke","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0310","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1242\/dev.110.1.73","article-title":"Cell shape changes during gastrulation in Drosophila","volume":"110","author":"Leptin","year":"1990","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0315","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/0092-8674(95)90293-7","article-title":"Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family","volume":"80","author":"Letsou","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0320","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1242\/dev.126.11.2355","article-title":"The notch pathway helps to pattern the tips of the Drosophila tracheal branches by selecting cell fates","volume":"126","author":"Llimargas","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0325","doi-asserted-by":"crossref","first-page":"4407","DOI":"10.1242\/dev.127.20.4407","article-title":"Wingless and its signalling pathway have common and separable functions during tracheal development","volume":"127","author":"Llimargas","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0330","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s004270050241","article-title":"EGF signalling regulates cell invagination as well as cell migration during formation of tracheal system in Drosophila","volume":"209","author":"Llimargas","year":"1999","journal-title":"Dev. Genes Evol."},{"key":"10.1016\/j.cdev.2025.203998_bb0335","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1146\/annurev.cellbio.20.010403.113126","article-title":"THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE","volume":"20","author":"Logan","year":"2004","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0340","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.865397","article-title":"The lateral epidermis actively counteracts pulling by the Amnioserosa during dorsal closure","volume":"10","author":"Lv","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0345","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nm.2653","article-title":"Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis","volume":"18","author":"Maeda","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.cdev.2025.203998_bb0350","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1101\/gad.12.4.557","article-title":"Puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure inDrosophila","volume":"12","author":"Mart\u00edn-Blanco","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0355","doi-asserted-by":"crossref","first-page":"4261","DOI":"10.1242\/dev.133322","article-title":"Escargot controls the sequential specification of two tracheal tip cell types by suppressing FGF signaling in Drosophila","volume":"143","author":"Miao","year":"2016","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0360","doi-asserted-by":"crossref","first-page":"4273","DOI":"10.1242\/dev.010397","article-title":"A wave of EGFR signaling determines cell alignment and intercalation in the Drosophila tracheal placode","volume":"134","author":"Nishimura","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0365","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.devcel.2018.06.004","article-title":"A switch-like activation relay of EGFR-ERK signaling regulates a wave of cellular contractility for epithelial invagination","volume":"46","author":"Ogura","year":"2018","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0370","doi-asserted-by":"crossref","first-page":"4837","DOI":"10.1242\/dev.124.23.4837","article-title":"Spitz and wingless, emanating from distinct borders, cooperate to establish cell fate across the engrailed domain in the Drosophila epidermis","volume":"124","author":"O\u2019Keefe","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0375","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1006882","article-title":"EGFR controls Drosophila tracheal tube elongation by intracellular trafficking regulation","volume":"13","author":"Olivares-Casti\u00f1eira","year":"2017","journal-title":"PLoS Genet."},{"key":"10.1016\/j.cdev.2025.203998_bb0380","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/ncb3420","article-title":"Amnioserosa cell constriction but not epidermal actin cable tension autonomously drives dorsal closure","volume":"18","author":"Pasakarnis","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0385","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/22330","article-title":"Ovo\/svb integrates wingless and DER pathways to control epidermis differentiation","volume":"400","author":"Payre","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.cdev.2025.203998_bb0390","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S1097-2765(05)00011-0","article-title":"Drosophila segment Borders result from unilateral repression of hedgehog activity by wingless signaling","volume":"6","author":"Piepenburg","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0395","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1101\/gad.11.13.1717","article-title":"Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure","volume":"11","author":"Riesgo-Escovar","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0400","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/0092-8674(95)90292-9","article-title":"An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo","volume":"80","author":"Ruberte","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0405","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/0012-1606(72)90129-7","article-title":"Ectodermal-mesodermal interactions in the growth of limb buds in the chick embryo: Constancy and temporal limits of the ectodermal induction","volume":"28","author":"Rubin","year":"1972","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cdev.2025.203998_bb0410","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.devcel.2015.03.016","article-title":"Decrease in cell volume generates contractile forces driving dorsal closure","volume":"33","author":"Saias","year":"2015","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cdev.2025.203998_bb0415","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1242\/dev.122.5.1395","article-title":"Development of the Drosophila tracheal system occurs by a series of morpho- logically distinct but genetically coupled branching events","volume":"122","author":"Samakovlis","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0420","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/dvdy.10293","article-title":"Differential expression of the two Drosophila fos\/kayak transcripts during oogenesis and embryogenesis","volume":"227","author":"Souid","year":"2003","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.cdev.2025.203998_bb0425","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0925-4773(99)00157-4","article-title":"Dpp and notch specify the fusion cell fate in the dorsal branches of the Drosophila trachea","volume":"87","author":"Steneberg","year":"1999","journal-title":"Mech. Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0430","first-page":"3209","article-title":"Antagonism between EGFR and wingless signalling in the larval cuticle of Drosophila","volume":"124","author":"Sz\u00fcts","year":"1997","journal-title":"Dev. Camb. Engl."},{"key":"10.1016\/j.cdev.2025.203998_bb0435","doi-asserted-by":"crossref","first-page":"3697","DOI":"10.1242\/dev.122.12.3697","article-title":"Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor escargot","volume":"122","author":"Tanaka-Matakatsu","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0440","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1242\/dev.124.14.2741","article-title":"DPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo","volume":"124","author":"Vincent","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0445","first-page":"4707","article-title":"Interactions between the EGF receptor and DPP pathways establish distinct cell fates in the tracheal placodes","volume":"124","author":"Wappner","year":"1997","journal-title":"Dev. Camb. Engl."},{"key":"10.1016\/j.cdev.2025.203998_bb0450","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1242\/dev.117.2.807","article-title":"An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo","volume":"117","author":"Wharton","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.cdev.2025.203998_bb0455","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1101\/gad.10.1.93","article-title":"Trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila","volume":"10","author":"Wilk","year":"1996","journal-title":"Genes Dev."},{"key":"10.1016\/j.cdev.2025.203998_bb0460","doi-asserted-by":"crossref","first-page":"7393","DOI":"10.1093\/emboj\/16.24.7393","article-title":"Defective dorsal closure and loss of epidermal decapentaplegic expression in Drosophila fos mutants","volume":"16","author":"Zeitlinger","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/j.cdev.2025.203998_bb0465","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1093\/humrep\/del086","article-title":"Role of sonic hedgehog in maintaining a pool of proliferating stem cells in the human fetal epidermis","volume":"21","author":"Zhou","year":"2006","journal-title":"Hum. Reprod. Oxf. Engl."}],"container-title":["Cells &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667290125000051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667290125000051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T11:27:32Z","timestamp":1778930852000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667290125000051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":93,"alternative-id":["S2667290125000051"],"URL":"https:\/\/doi.org\/10.1016\/j.cdev.2025.203998","relation":{},"ISSN":["2667-2901"],"issn-type":[{"value":"2667-2901","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A tale of two tissues: Patterning of the epidermis through morphogens and their role in establishing tracheal system organization","name":"articletitle","label":"Article Title"},{"value":"Cells & Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cdev.2025.203998","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"203998"}}