{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T07:14:06Z","timestamp":1773904446851,"version":"3.50.1"},"reference-count":44,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","award":["K01AI136885"],"award-info":[{"award-number":["K01AI136885"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Gates Foundation","doi-asserted-by":"publisher","award":["OPPGD759"],"award-info":[{"award-number":["OPPGD759"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006978","name":"University of California Berkeley","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006978","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cdn.nutrition.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Developments in Nutrition"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.cdnut.2025.107596","type":"journal-article","created":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T16:15:15Z","timestamp":1762618515000},"page":"107596","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations Between Micronutrient Status, Hormones, and Immune Status During Pregnancy and Child Growth in Rural Bangladesh: A Prospective Cohort Study"],"prefix":"10.1016","volume":"9","author":[{"given":"Belinda","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew N","family":"Mertens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Hsien","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophia T","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farheen","family":"Jamshed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Figueroa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caitlin","family":"Hemlock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary","family":"Butzin-Dozier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lia CH","family":"Fernald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine P","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan E","family":"Hubbard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md Ziaur","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahjahan","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin F","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firdaus S","family":"Dhabhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas A","family":"Granger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahbubur","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen P","family":"Luby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"John M","family":"Colford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3877-3469","authenticated-orcid":false,"given":"Audrie","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10064","key":"10.1016\/j.cdnut.2025.107596_bib1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0140-6736(16)31389-7","article-title":"Advancing early childhood development: from science to scale 1","volume":"389","author":"Black","year":"2017","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.cdnut.2025.107596_bib2","doi-asserted-by":"crossref","first-page":"896","DOI":"10.3945\/ajcn.112.047639","article-title":"The effect of multiple anthropometric deficits on child mortality: meta-analysis of individual data in 10 prospective studies from developing countries","volume":"97","author":"McDonald","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"issue":"5","key":"10.1016\/j.cdnut.2025.107596_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0064636","article-title":"Associations of suboptimal growth with all-cause and cause-specific mortality in children under five years: a pooled analysis of ten prospective studies","volume":"8","author":"Olofin","year":"2013","journal-title":"PLOS One"},{"issue":"9890","key":"10.1016\/j.cdnut.2025.107596_bib4","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0140-6736(13)60937-X","article-title":"Maternal and child undernutrition and overweight in low-income and middle-income countries","volume":"382","author":"Black","year":"2013","journal-title":"Lancet"},{"issue":"9891","key":"10.1016\/j.cdnut.2025.107596_bib5","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0140-6736(13)60103-8","article-title":"Associations of linear growth and relative weight gain during early life with adult health and human capital in countries of low and middle income: findings from five birth cohort studies","volume":"382","author":"Adair","year":"2013","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.cdnut.2025.107596_bib6","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3945\/ajcn.115.123968","article-title":"Schooling and wage income losses due to early-childhood growth faltering in developing countries: national, regional, and global estimates","volume":"104","author":"Fink","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"issue":"7","key":"10.1016\/j.cdnut.2025.107596_bib7","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s13280-018-1101-4","article-title":"Sustainable development goal 2: improved targets and indicators for agriculture and food security","volume":"48","author":"Gil","year":"2019","journal-title":"Ambio"},{"issue":"2","key":"10.1016\/j.cdnut.2025.107596_bib8","doi-asserted-by":"crossref","DOI":"10.1002\/ajhb.22952","article-title":"Improved nutrition in the first 1000 days and adult human capital and health","volume":"29","author":"Martorell","year":"2017","journal-title":"Am. J. Hum. Biol."},{"issue":"2","key":"10.1016\/j.cdnut.2025.107596_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0086928","article-title":"Stunting is characterized by chronic inflammation in Zimbabwean infants","volume":"9","author":"Prendergast","year":"2014","journal-title":"PLOS ONE"},{"issue":"4","key":"10.1016\/j.cdnut.2025.107596_bib10","doi-asserted-by":"crossref","first-page":"469","DOI":"10.5114\/ceji.2020.103422","article-title":"Chronic inflammation and the growth hormone\/insulin-like growth factor-1 axis","volume":"45","author":"Witkowska-S\u0119dek","year":"2021","journal-title":"Cent. Eur. J. Immunol."},{"key":"10.1016\/j.cdnut.2025.107596_bib11","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.bbi.2019.04.021","article-title":"Maternal pro-inflammatory state during pregnancy and newborn leukocyte telomere length: a prospective investigation","volume":"80","author":"Lazarides","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.cdnut.2025.107596_bib12","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1055\/s-0038-1677472","article-title":"Early postnatal IGF-1 and IGFBP-1 blood levels in extremely preterm infants: relationships with indicators of placental insufficiency and with systemic inflammation","volume":"36","author":"Leviton","year":"2019","journal-title":"Am. J. Perinatol"},{"key":"10.1016\/j.cdnut.2025.107596_bib13","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ghir.2017.11.006","article-title":"Increased postnatal concentrations of pro-inflammatory cytokines are associated with reduced IGF-I levels and retinopathy of prematurity","volume":"39","author":"Hellgren","year":"2018","journal-title":"Growth Horm. IGF Res."},{"issue":"2","key":"10.1016\/j.cdnut.2025.107596_bib14","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.atherosclerosissup.2005.02.005","article-title":"Markers of inflammation and their clinical significance","volume":"6","author":"Ballantyne","year":"2005","journal-title":"Atheroscler. Suppl."},{"issue":"12","key":"10.1016\/j.cdnut.2025.107596_bib15","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1038\/ncpgasthep0359","article-title":"The role of C-reactive protein as an inflammatory marker in gastrointestinal diseases","volume":"2","author":"Vermeire","year":"2005","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.cdnut.2025.107596_bib16","series-title":"Biology of C-Reactive Protein in Health and Disease","first-page":"67","article-title":"Inflammation and inflammatory diseases, markers, and mediators: role of CRP in some inflammatory diseases","author":"Ansar","year":"2016"},{"issue":"3","key":"10.1016\/j.cdnut.2025.107596_bib17","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF00731326","article-title":"Glycoforms of serum \u03b11-acid glycoprotein as markers of inflammation and cancer","volume":"12","author":"Mackiewicz","year":"1995","journal-title":"Glycoconj. J."},{"issue":"1\u20132","key":"10.1016\/j.cdnut.2025.107596_bib18","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0167-4838(00)00153-9","article-title":"Alpha-1-acid glycoprotein","volume":"1482","author":"Fournier","year":"2000","journal-title":"Biochim. Biophys. Acta."},{"issue":"2","key":"10.1016\/j.cdnut.2025.107596_bib19","first-page":"52","article-title":"Effects of prenatal stress on pregnancy and human development: mechanisms and pathways, Obstet","volume":"6","author":"Coussons-Read","year":"2013","journal-title":"Med."},{"issue":"1","key":"10.1016\/j.cdnut.2025.107596_bib20","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.jri.2009.10.011","article-title":"Stress in early pregnancy: maternal neuro-endocrine-immune responses and effects","volume":"85","author":"Parker","year":"2010","journal-title":"J. Reprod. Immunol."},{"issue":"3","key":"10.1016\/j.cdnut.2025.107596_bib21","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/00001648-200005000-00015","article-title":"Maternal pregnancy estriol levels in relation to anamnestic and fetal anthropometric data","volume":"11","author":"Kaijser","year":"2000","journal-title":"Epidemiology"},{"issue":"3","key":"10.1016\/j.cdnut.2025.107596_bib22","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/S0029-7844(97)00677-7","article-title":"Association of low unconjugated estriol in the second trimester and adverse pregnancy outcome","volume":"91","author":"Kowalczyk","year":"1998","journal-title":"Obstet. Gynecol."},{"issue":"12","key":"10.1016\/j.cdnut.2025.107596_bib23","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.placenta.2010.08.015","article-title":"Vitamin D effects on pregnancy and the placenta","volume":"31","author":"Shin","year":"2010","journal-title":"Placenta"},{"issue":"2S Suppl","key":"10.1016\/j.cdnut.2025.107596_bib24","doi-asserted-by":"crossref","first-page":"443S","DOI":"10.1093\/jn\/130.2.443S","article-title":"Anemia, iron and pregnancy outcome","volume":"130","author":"Scholl","year":"2000","journal-title":"J. Nutr."},{"issue":"4","key":"10.1016\/j.cdnut.2025.107596_bib25","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.ajog.2020.03.006","article-title":"Iron deficiency in pregnancy","volume":"223","author":"Georgieff","year":"2020","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"3","key":"10.1016\/j.cdnut.2025.107596_bib26","doi-asserted-by":"crossref","first-page":"681","DOI":"10.3390\/nu11030681","article-title":"Vitamin A and pregnancy: a narrative review","volume":"11","author":"Bastos Maia","year":"2019","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.cdnut.2025.107596_bib27","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ejogrb.2012.06.020","article-title":"Influence of mineral and vitamin supplements on pregnancy outcome","volume":"164","author":"Hovdenak","year":"2012","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"8","key":"10.1016\/j.cdnut.2025.107596_bib28","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2013-003476","article-title":"Cluster-randomised controlled trials of individual and combined water, sanitation, hygiene and nutritional interventions in rural Bangladesh and Kenya: the WASH Benefits study design and rationale","volume":"3","author":"Arnold","year":"2013","journal-title":"BMJ Open"},{"issue":"4","key":"10.1016\/j.cdnut.2025.107596_bib29","first-page":"255","article-title":"Effects of water quality, sanitation, handwashing, and nutritional interventions on child development in rural Bangladesh (WASH Benefits Bangladesh): a cluster-randomised controlled trial, Lancet Child Adolesc","volume":"2","author":"Tofail","year":"2018","journal-title":"Health"},{"issue":"3","key":"10.1016\/j.cdnut.2025.107596_bib30","doi-asserted-by":"crossref","first-page":"e302","DOI":"10.1016\/S2214-109X(17)30490-4","article-title":"Effects of water quality, sanitation, handwashing, and nutritional interventions on diarrhoea and child growth in rural Bangladesh: a cluster randomised controlled trial","volume":"6","author":"Luby","year":"2018","journal-title":"Lancet Glob. Health"},{"issue":"5","key":"10.1016\/j.cdnut.2025.107596_bib32","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1093\/cid\/ciz291","article-title":"Effects of water, sanitation, handwashing, and nutritional interventions on environmental enteric dysfunction in young children: a cluster-randomized, controlled trial in rural Bangladesh","volume":"70","author":"Lin","year":"2020","journal-title":"Clin. Infect. Dis."},{"issue":"11","key":"10.1016\/j.cdnut.2025.107596_bib33","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1093\/jn\/134.11.3127","article-title":"Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique","volume":"134","author":"Erhardt","year":"2004","journal-title":"J. Nutr."},{"issue":"Suppl 1","key":"10.1016\/j.cdnut.2025.107596_bib34","doi-asserted-by":"crossref","first-page":"333S","DOI":"10.3945\/ajcn.116.142273","article-title":"BRINDA Working Group, Methodologic approach for the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project","volume":"106","author":"Namaste","year":"2017","journal-title":"Am. J. Clin. Nutr."},{"issue":"8","key":"10.1016\/j.cdnut.2025.107596_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.cdnut.2023.101969","article-title":"Micronutrient status during pregnancy is associated with child immune status in rural Bangladesh","volume":"7","author":"Jung","year":"2023","journal-title":"Curr. Dev. Nutr."},{"key":"10.1016\/j.cdnut.2025.107596_bib36","series-title":"Anthropometric indicators measurement guide. Food and Nutrition Technical Assistance Project","author":"Cogill","year":"2003"},{"issue":"1 Suppl","key":"10.1016\/j.cdnut.2025.107596_bib37","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1177\/15648265040251S105","article-title":"Measurement and standardization protocols for anthropometry used in the construction of a new international growth reference","volume":"25","author":"de Onis","year":"2004","journal-title":"Food Nutr. Bull."},{"key":"10.1016\/j.cdnut.2025.107596_bib38","unstructured":"WHO. WHO Anthro Survey Analyser and other tools. [cited September 1, 2025]. https:\/\/www.who.int\/tools\/child-growth-standards\/software."},{"key":"10.1016\/j.cdnut.2025.107596_bib39","doi-asserted-by":"crossref","unstructured":"J. Coates, A. Swindale, P. Bilinsky, Household Food Insecurity Access Scale (HFIAS) for Measurement of Food Access: Indicator Guide, Version 3, Food and Nutrition Technical Assistance Project (FANTA), Washington, DC (2007)","DOI":"10.1037\/e576842013-001"},{"issue":"3","key":"10.1016\/j.cdnut.2025.107596_bib40","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1073\/pnas.0337600100","article-title":"Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2","volume":"100","author":"Leung","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"12","key":"10.1016\/j.cdnut.2025.107596_bib41","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1038\/nri2449","article-title":"Nutrient sensing and inflammation in metabolic diseases","volume":"8","author":"Hotamisligil","year":"2008","journal-title":"Nat. Rev. Immunol."},{"issue":"Suppl 1","key":"10.1016\/j.cdnut.2025.107596_bib42","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1365-3016.2012.01284.x","article-title":"Vitamin A and carotenoids during pregnancy and maternal, neonatal and infant health outcomes: a systematic review and meta-analysis","volume":"26","author":"Thorne-Lyman","year":"2012","journal-title":"Paediatr. Perinat. Epidemiol."},{"issue":"10","key":"10.1016\/j.cdnut.2025.107596_bib43","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3390\/children6100116","article-title":"Environmental and genetic determinants of serum 25(OH)-vitamin D levels during pregnancy and early childhood","volume":"6","author":"Schoos","year":"2019","journal-title":"Children"},{"key":"10.1016\/j.cdnut.2025.107596_bib44","unstructured":"World Health Organization, Guideline: Vitamin D Supplementation in Pregnant Women, WHO, Geneva, 2012 [cited September 1, 2025] https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK310616\/."},{"key":"10.1016\/j.cdnut.2025.107596_bib45","doi-asserted-by":"crossref","unstructured":"Vestergaard AL, Justesen S, Volqvartz T, Aagaard SK, Andreasen MF, Lesnikova I, Uldbjerg N, Larsen A, Bor P. Vitamin D insufficiency among Danish pregnant women-Prevalence and association with adverse obstetric outcomes and placental vitamin D metabolism. Acta Obstet Gynecol Scand. 2021 Mar;100(3):480-488. https:\/\/doi.org\/10.1111\/aogs.14019. Epub 2021 Jan 12. PMID: 33030742.","DOI":"10.1111\/aogs.14019"}],"container-title":["Current Developments in Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2475299125030586?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2475299125030586?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T03:27:26Z","timestamp":1773890846000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2475299125030586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S2475299125030586"],"URL":"https:\/\/doi.org\/10.1016\/j.cdnut.2025.107596","relation":{},"ISSN":["2475-2991"],"issn-type":[{"value":"2475-2991","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Associations Between Micronutrient Status, Hormones, and Immune Status During Pregnancy and Child Growth in Rural Bangladesh: A Prospective Cohort Study","name":"articletitle","label":"Article Title"},{"value":"Current Developments in Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cdnut.2025.107596","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc. on behalf of American Society for Nutrition.","name":"copyright","label":"Copyright"}],"article-number":"107596"}}