{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:18:43Z","timestamp":1787930323930,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,8,19]],"date-time":"2015-08-19T00:00:00Z","timestamp":1439942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010337","name":"People\u2019s Liberation Army Navy General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010337","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tongzhou Maternal and Child Health Hospital of Beijing, Beijing, China"},{"name":"General Hospital of Beijing Military Region"},{"name":"Center Hospital of Aviation Industry"},{"name":"Pinggu Maternal and Child Health Hospital of Beijing, Beijing, China"},{"name":"Beijing Hospital of Miyun City"},{"DOI":"10.13039\/501100010337","name":"Navy General Hospital","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010337","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Beijing Daxing District Hongxing Hospital"},{"name":"Beijing Chui Yang Liu Hospital"},{"name":"Peking University Shougang Hospital"},{"name":"Combined with Traditional Chinese and Western Medicine Hospital of Beijing City"},{"name":"Beijing No.6 Hospital"},{"name":"Beijing Changping Hospital of Traditional Chinese Medicine"},{"name":"General Hospital of Jingmei Group"},{"name":"World Diabetes Foundation","award":["WDF 10-517"],"award-info":[{"award-number":["WDF 10-517"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chronic Diseases and Translational Medicine"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the adverse maternal and neonatal outcomes of multiple pregnancy and singleton pregnancy from multiple medical centers in Beijing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data concerning maternal and neonatal adverse outcomes in multiple and singleton pregnancies were collected from 15 hospitals in Beijing by a systemic cluster sampling survey conducted from 20 June to 30 November 2013. The SPSS software (version 20.0) was used for data analysis. The \u03c7<jats:sup>2<\/jats:sup> test was used for statistical analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The rate of caesarean deliveries was much higher in women with multiple pregnancies (85.8%) than that in women with singleton pregnancies (42.6%, \u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a0190.8, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). The incidences of anemia (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a040.023, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), preterm labor (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a01021.172, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), gestational diabetes mellitus (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a09.311, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01), hypertensive disorders (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a0122.708, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and post\u2010partum hemorrhage (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a048.550, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) was significantly increased with multiple pregnancy. In addition, multiple pregnancy was associated with a significantly higher rate of small\u2010for\u2010gestational\u2010age infants (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a092.602, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), low birth weight (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a01141.713, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), and neonatal intensive care unit (NICU) admission (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a0340.129, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Multiple pregnancy is a significant risk factor for adverse maternal and neonatal outcomes in Beijing. Improving obstetric care for multiple pregnancy, particularly in reducing preterm labor, is required to reduce the risk to mothers and infants.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.cdtm.2015.08.004","type":"journal-article","created":{"date-parts":[[2015,9,27]],"date-time":"2015-09-27T07:27:57Z","timestamp":1443338877000},"page":"197-202","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Maternal and neonatal outcomes in multiple pregnancy: A multicentre study in the Beijing population"],"prefix":"10.1002","volume":"1","author":[{"given":"Ri\u2010Na","family":"Su","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Peking University First Hospital Beijing 100034 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010Wei","family":"Zhu","sequence":"additional","affiliation":[{"name":"National Institute of Hospital Administration Beijing 100191 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