{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:06:07Z","timestamp":1791173167709,"version":"4.1.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Calcium"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.ceca.2011.04.001","type":"journal-article","created":{"date-parts":[[2011,5,21]],"date-time":"2011-05-21T23:13:56Z","timestamp":1306019636000},"page":"242-250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":247,"title":["A dual role for Ca2+ in autophagy regulation"],"prefix":"10.1016","volume":"50","author":[{"given":"Jean-Paul","family":"Decuypere","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geert","family":"Bultynck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan B.","family":"Parys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ceca.2011.04.001_bib0005","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1152\/physrev.00030.2009","article-title":"Regulation of mammalian autophagy in physiology and pathophysiology","volume":"90","author":"Ravikumar","year":"2010","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ceca.2011.04.001_bib0010","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/nrm2708","article-title":"Dynamics and diversity in autophagy mechanisms: lessons from yeast","volume":"10","author":"Nakatogawa","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0015","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nature09782","article-title":"Autophagy in immunity and inflammation","volume":"469","author":"Levine","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.ceca.2011.04.001_bib0020","doi-asserted-by":"crossref","first-page":"555","DOI":"10.4161\/auto.6.4.11812","article-title":"Quality control autophagy: a joint effort of ubiquitin, protein deacetylase and actin cytoskeleton","volume":"6","author":"Lee","year":"2010","journal-title":"Autophagy"},{"key":"10.1016\/j.ceca.2011.04.001_bib0025","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cell.2007.12.018","article-title":"Autophagy in the pathogenesis of disease","volume":"132","author":"Levine","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.ceca.2011.04.001_bib0030","first-page":"493","article-title":"Autophagy: can it become a potential therapeutic target?","volume":"25","author":"Bao","year":"2010","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.ceca.2011.04.001_bib0035","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/ncb0910-823","article-title":"Autophagy in mammalian development and differentiation","volume":"12","author":"Mizushima","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0040","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/978-1-59745-157-4_16","article-title":"Microautophagy in the yeast Saccharomyces cerevisiae","volume":"445","author":"Uttenweiler","year":"2008","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0045","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.semcdb.2010.02.005","article-title":"Chaperone-mediated autophagy: molecular mechanisms and physiological relevance","volume":"21","author":"Orenstein","year":"2010","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0050","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ceb.2009.12.004","article-title":"The role of the Atg1\/ULK1 complex in autophagy regulation","volume":"22","author":"Mizushima","year":"2010","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0055","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ceb.2010.01.001","article-title":"The Beclin 1 interactome","volume":"22","author":"He","year":"2010","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0060","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1016\/j.febslet.2010.01.011","article-title":"Regulation of autophagy by phosphatidylinositol 3-phosphate","volume":"584","author":"Burman","year":"2010","journal-title":"FEBS Lett."},{"key":"10.1016\/j.ceca.2011.04.001_bib0065","doi-asserted-by":"crossref","first-page":"561","DOI":"10.4161\/auto.4713","article-title":"Differential interactions between Beclin 1 and Bcl-2 family members","volume":"3","author":"Erlich","year":"2007","journal-title":"Autophagy"},{"key":"10.1016\/j.ceca.2011.04.001_bib0070","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.molcel.2008.06.001","article-title":"JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy","volume":"30","author":"Wei","year":"2008","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ceca.2011.04.001_bib0075","doi-asserted-by":"crossref","first-page":"720","DOI":"10.4161\/auto.5.5.8625","article-title":"Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL","volume":"5","author":"Zalckvar","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.ceca.2011.04.001_bib0080","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1038\/embor.2008.163","article-title":"The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. \u2018Protein modifications: beyond the usual suspects\u2019 review series","volume":"9","author":"Geng","year":"2008","journal-title":"EMBO Rep."},{"key":"10.1016\/j.ceca.2011.04.001_bib0085","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/cr.2010.82","article-title":"Overview of macroautophagy regulation in mammalian cells","volume":"20","author":"Mehrpour","year":"2010","journal-title":"Cell Res."},{"key":"10.1016\/j.ceca.2011.04.001_bib0090","doi-asserted-by":"crossref","first-page":"26107","DOI":"10.1016\/S0021-9258(19)74287-2","article-title":"Dependence of hepatocytic autophagy on intracellularly sequestered calcium","volume":"268","author":"Gordon","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ceca.2011.04.001_bib0095","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1083\/jcb.200504035","article-title":"Lithium induces autophagy by inhibiting inositol monophosphatase","volume":"170","author":"Sarkar","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0100","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1038\/sj.cdd.4402099","article-title":"Regulation of autophagy by the inositol trisphosphate receptor","volume":"14","author":"Criollo","year":"2007","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.ceca.2011.04.001_bib0105","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1038\/cdd.2009.34","article-title":"The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1","volume":"16","author":"Vicencio","year":"2009","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.ceca.2011.04.001_bib0110","doi-asserted-by":"crossref","first-page":"16912","DOI":"10.1074\/jbc.M110.114207","article-title":"Role of inositol trisphosphate receptors in autophagy in DT40 cells","volume":"285","author":"Khan","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ceca.2011.04.001_bib0115","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.cell.2010.06.007","article-title":"Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria","volume":"142","author":"C\u00e1rdenas","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.ceca.2011.04.001_bib0120","doi-asserted-by":"crossref","first-page":"912","DOI":"10.4161\/auto.6.7.13290","article-title":"Glucocorticoids downregulate Fyn and inhibit IP3-mediated calcium signaling to promote autophagy in T lymphocytes","volume":"6","author":"Harr","year":"2010","journal-title":"Autophagy"},{"key":"10.1016\/j.ceca.2011.04.001_bib0125","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/nchembio.79","article-title":"Novel targets for Huntington's disease in an mTOR-independent autophagy pathway","volume":"4","author":"Williams","year":"2008","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0130","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1096\/fj.05-4305fje","article-title":"Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy","volume":"20","author":"Buytaert","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.ceca.2011.04.001_bib0135","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.molcel.2006.12.009","article-title":"Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2","volume":"25","author":"H\u00f8yer-Hansen","year":"2007","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ceca.2011.04.001_bib0140","doi-asserted-by":"crossref","first-page":"15370","DOI":"10.1074\/jbc.M710209200","article-title":"Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum","volume":"283","author":"Sakaki","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ceca.2011.04.001_bib0145","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1007\/s00018-008-8383-9","article-title":"Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway","volume":"65","author":"Wang","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ceca.2011.04.001_bib0150","doi-asserted-by":"crossref","first-page":"754","DOI":"10.4161\/auto.6360","article-title":"Induction of macroautophagy by exogenously introduced calcium","volume":"4","author":"Gao","year":"2008","journal-title":"Autophagy"},{"key":"10.1016\/j.ceca.2011.04.001_bib0155","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1091\/mbc.e07-08-0823","article-title":"The inositol 1,4,5-trisphosphate receptor is required to signal autophagic cell death","volume":"19","author":"Lam","year":"2008","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ceca.2011.04.001_bib0160","doi-asserted-by":"crossref","first-page":"9100","DOI":"10.1074\/jbc.M109.060061","article-title":"AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism","volume":"285","author":"Vingtdeux","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ceca.2011.04.001_bib0165","doi-asserted-by":"crossref","first-page":"6064","DOI":"10.1073\/pnas.0909794107","article-title":"Mechanisms of acute axonal degeneration in the optic nerve in vivo","volume":"107","author":"Kn\u00f6ferle","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ceca.2011.04.001_bib0170","doi-asserted-by":"crossref","first-page":"607","DOI":"10.4161\/auto.6.5.11964","article-title":"Ca2+-dependent autophagy is enhanced by the pharmacological agent PK11195: pharmacological tools in autophagy","volume":"6","author":"Gastaldello","year":"2010","journal-title":"Autophagy"},{"key":"10.1016\/j.ceca.2011.04.001_bib0175","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.cellsig.2010.01.015","article-title":"AMPK-independent induction of autophagy by cytosolic Ca2+ increase","volume":"22","author":"Grotemeier","year":"2010","journal-title":"Cell. Signal."},{"key":"10.1016\/j.ceca.2011.04.001_bib0180","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1158\/1535-7163.MCT-09-0700","article-title":"Alisol B, a novel inhibitor of the sarcoplasmic\/endoplasmic reticulum Ca2+ ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis","volume":"9","author":"Law","year":"2010","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.ceca.2011.04.001_bib0185","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.1111\/j.1742-4658.2007.05849.x","article-title":"The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco\/endoplasmic reticulum calcium stores","volume":"274","author":"Brady","year":"2007","journal-title":"FEBS J."},{"key":"10.1016\/j.ceca.2011.04.001_bib0190","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1152\/physrev.00035.2006","article-title":"Inositol trisphosphate receptor Ca2+ release channels","volume":"87","author":"Foskett","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ceca.2011.04.001_bib0195","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.bbamcr.2008.10.005","article-title":"Inositol trisphosphate and calcium signalling mechanisms","volume":"1793","author":"Berridge","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ceca.2011.04.001_bib0200","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1113\/jphysiol.2006.109504","article-title":"Graded recruitment and inactivation of single InsP3 receptor Ca2+-release channels: implications for quantal [corrected] Ca2+ release","volume":"573","author":"Ionescu","year":"2006","journal-title":"J. Physiol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0205","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0143416002001859","article-title":"IP3 receptors and their regulation by calmodulin and cytosolic Ca2+","volume":"32","author":"Taylor","year":"2002","journal-title":"Cell Calcium"},{"key":"10.1016\/j.ceca.2011.04.001_bib0210","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S1570-9639(02)00440-5","article-title":"The role of calmodulin for inositol 1,4,5-trisphosphate receptor function","volume":"1600","author":"Nadif Kasri","year":"2002","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ceca.2011.04.001_bib0215","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.bbamcr.2008.12.003","article-title":"Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation","volume":"1793","author":"Vanderheyden","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ceca.2011.04.001_bib0220","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.neuron.2010.11.010","article-title":"Mechanism of ER stress-induced brain damage by IP3 receptor","volume":"68","author":"Higo","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.ceca.2011.04.001_bib0225","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.ceca.2007.04.005","article-title":"The complex regulatory function of the ligand-binding domain of the inositol 1,4,5-trisphosphate receptor","volume":"43","author":"Devogelaere","year":"2007","journal-title":"Cell Calcium"},{"key":"10.1016\/j.ceca.2011.04.001_bib0230","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.molcel.2008.06.014","article-title":"Targeting Bcl-2\u2013IP3 receptor interaction to reverse Bcl-2s inhibition of apoptotic calcium signals","volume":"31","author":"Rong","year":"2008","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ceca.2011.04.001_bib0235","doi-asserted-by":"crossref","first-page":"13678","DOI":"10.1074\/jbc.M109.096040","article-title":"Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling","volume":"285","author":"Eckenrode","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"Suppl. 2","key":"10.1016\/j.ceca.2011.04.001_bib0240","first-page":"26","article-title":"The BH4 domains of Bcl-2 and Bcl-Xl differentially regulate inositol 1,4,5-trisphosphate receptors and apoptosis","volume":"57","author":"Monaco","year":"2010","journal-title":"Acta Biochim. Pol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0245","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.cellsig.2010.08.005","article-title":"Mammalian target of rapamycin (mTOR) phosphorylates inositol 1,4,5-trisphosphate receptor type 2 and increases its Ca2+ release activity","volume":"23","author":"Regimbald-Dumas","year":"2011","journal-title":"Cell. Signal."},{"key":"10.1016\/j.ceca.2011.04.001_bib0250","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/jcb.23006","article-title":"Positive regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by mammalian target of rapamycin (mTOR) in RINm5F cells","volume":"112","author":"Fregeau","year":"2011","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.ceca.2011.04.001_bib0255","doi-asserted-by":"crossref","first-page":"3182","DOI":"10.1074\/jbc.M511547200","article-title":"Dissection of the functional differences between human secretory pathway Ca2+\/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses","volume":"281","author":"Dode","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ceca.2011.04.001_bib0260","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S0165-6147(98)01243-7","article-title":"Pharmacological analysis of intracellular Ca2+ signalling: problems and pitfalls","volume":"19","author":"Taylor","year":"1998","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.ceca.2011.04.001_bib0265","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1054\/ceca.2000.0163","article-title":"2-Aminoethoxydiphenyl borate affects the inositol 1,4,5-trisphosphate receptor, the intracellular Ca2+ pump and the non-specific Ca2+ leak from the non-mitochondrial Ca2+ stores in permeabilized A7r5 cells","volume":"29","author":"Missiaen","year":"2001","journal-title":"Cell Calcium"},{"key":"10.1016\/j.ceca.2011.04.001_bib0270","doi-asserted-by":"crossref","first-page":"3678","DOI":"10.1046\/j.1432-1033.2002.03060.x","article-title":"Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB). 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites","volume":"269","author":"Bilmen","year":"2002","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.ceca.2011.04.001_bib0275","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.bbrc.2003.08.084","article-title":"Calcineurin and intracellular Ca2+-release channels: regulation or association?","volume":"311","author":"Bultynck","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ceca.2011.04.001_bib0280","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0092-8674(95)90124-8","article-title":"Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux","volume":"83","author":"Cameron","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.ceca.2011.04.001_bib0285","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1093\/emboj\/20.11.2690","article-title":"The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action","volume":"20","author":"Pinton","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.ceca.2011.04.001_bib0290","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1073\/pnas.0408352102","article-title":"Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum","volume":"102","author":"Oakes","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ceca.2011.04.001_bib0295","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.bbamcr.2010.11.023","article-title":"IP3 receptor-mitochondria connection in apoptosis and autophagy","volume":"1813","author":"Decuypere","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ceca.2011.04.001_bib0300","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1111\/j.1600-0854.2009.00924.x","article-title":"The Ca2+ channel TRPML3 regulates membrane trafficking and autophagy","volume":"10","author":"Kim","year":"2009","journal-title":"Traffic"},{"key":"10.1016\/j.ceca.2011.04.001_bib0305","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.ceb.2009.11.004","article-title":"Lethal weapons: DAP-kinase, autophagy and cell death: DAP-kinase regulates autophagy","volume":"22","author":"Bialik","year":"2010","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ceca.2011.04.001_bib0310","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/embor.2008.246","article-title":"DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy","volume":"10","author":"Zalckvar","year":"2009","journal-title":"EMBO Rep."},{"key":"10.1016\/j.ceca.2011.04.001_bib0315","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1084\/jem.20030527","article-title":"Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+\/calmodulin-PI3K hVPS34 cascade","volume":"198","author":"Vergne","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ceca.2011.04.001_bib0320","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1042\/BJ20081865","article-title":"hVps15, but not Ca2+\/CaM, is required for the activity and regulation of hVps34 in mammalian cells","volume":"417","author":"Yan","year":"2009","journal-title":"Biochem. J."},{"key":"10.1016\/j.ceca.2011.04.001_bib0325","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/cr.2009.129","article-title":"S100A8\/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3","volume":"20","author":"Ghavami","year":"2010","journal-title":"Cell Res."},{"key":"10.1016\/j.ceca.2011.04.001_bib0330","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s12311-009-0125-5","article-title":"Bergmann glial S100B activates myo-inositol monophosphatase 1 and Co-localizes to purkinje cell vacuoles in SCA1 transgenic mice","volume":"8","author":"Vig","year":"2009","journal-title":"Cerebellum"},{"key":"10.1016\/j.ceca.2011.04.001_bib0335","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1038\/sj.emboj.7600104","article-title":"Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis","volume":"23","author":"Bassik","year":"2004","journal-title":"EMBO J."}],"container-title":["Cell Calcium"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143416011000716?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143416011000716?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T20:13:18Z","timestamp":1758917598000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143416011000716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0143416011000716"],"URL":"https:\/\/doi.org\/10.1016\/j.ceca.2011.04.001","relation":{},"ISSN":["0143-4160"],"issn-type":[{"value":"0143-4160","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A dual role for Ca2+ in autophagy regulation","name":"articletitle","label":"Article Title"},{"value":"Cell Calcium","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ceca.2011.04.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}