{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:04:53Z","timestamp":1791291893213,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK080840"],"award-info":[{"award-number":["DK080840"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GM083913"],"award-info":[{"award-number":["GM083913"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Calcium"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.ceca.2012.04.004","type":"journal-article","created":{"date-parts":[[2012,5,10]],"date-time":"2012-05-10T00:02:03Z","timestamp":1336608123000},"page":"459-469","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Actin cytoskeleton controls movement of intracellular organelles in pancreatic duct epithelial cells"],"prefix":"10.1016","volume":"51","author":[{"given":"Seung-Ryoung","family":"Jung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Bae","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghwan","family":"Shim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertil","family":"Hille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duk-Su","family":"Koh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ceca.2012.04.004_bib0005","series-title":"Cell Movements: From Molecules to Motility","author":"Bray","year":"2000"},{"key":"10.1016\/j.ceca.2012.04.004_bib0010","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1083\/jcb.102.4.1459","article-title":"Is a rise in intracellular concentration of free calcium necessary or sufficient for stimulated cytoskeletal-associated actin?","volume":"102","author":"Sha\u2019afi","year":"1986","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0015","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1083\/jcb.110.6.1975","article-title":"Actin assembly in electropermeabilized neutrophils: role of intracellular calcium","volume":"110","author":"Downey","year":"1990","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0020","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1242\/jcs.02942","article-title":"Regulation of pancreatic \u03b2-cell insulin secretion by actin cytoskeleton remodeling: role of gelsolin and cooperation with the MAPK signaling pathway","volume":"119","author":"Tomas","year":"2006","journal-title":"Journal of Cell Science"},{"key":"10.1016\/j.ceca.2012.04.004_bib0025","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1083\/jcb.128.4.589","article-title":"Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells","volume":"128","author":"Muallem","year":"1995","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0030","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1023\/A:1021627800918","article-title":"Pathways that control cortical F-actin dynamics during secretion","volume":"27","author":"Trifaro","year":"2002","journal-title":"Neurochemical Research"},{"key":"10.1016\/j.ceca.2012.04.004_bib0035","doi-asserted-by":"crossref","first-page":"C46","DOI":"10.1152\/ajpcell.00397.2004","article-title":"Barrier role of actin filaments in regulated mucin secretion from airway goblet cells","volume":"288","author":"Ehre","year":"2005","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0040","doi-asserted-by":"crossref","first-page":"10716","DOI":"10.1074\/jbc.M709876200","article-title":"Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4","volume":"283","author":"Jewell","year":"2008","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.ceca.2012.04.004_bib0045","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1085\/jgp.116.4.507","article-title":"Regulation of exocytosis by protein kinases and Ca2+ in pancreatic duct epithelial cells","volume":"116","author":"Koh","year":"2000","journal-title":"Journal of General Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0050","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1152\/ajpcell.00350.2003","article-title":"Regulation of exocytosis by purinergic receptors in pancreatic duct epithelial cells","volume":"286","author":"Jung","year":"2004","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0055","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1113\/jphysiol.2006.114876","article-title":"Pattern of Ca2+ increase determines the type of secretory mechanism activated in dog pancreatic duct epithelial cells","volume":"576","author":"Jung","year":"2006","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0060","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1111\/j.1600-0854.2009.00884.x","article-title":"Control of granule movement and exocytosis by Ca2+-dependent F-actin formation in pancreatic duct epithelial cells","volume":"10","author":"Jung","year":"2009","journal-title":"Traffic"},{"key":"10.1016\/j.ceca.2012.04.004_bib0065","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1085\/jgp.200910355","article-title":"Cyclic AMP potentiates Ca2+-dependent exocytosis in pancreatic duct epithelial cells","volume":"135","author":"Jung","year":"2010","journal-title":"Journal of General Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0070","doi-asserted-by":"crossref","first-page":"18711","DOI":"10.1074\/jbc.M801655200","article-title":"Protease-activated receptor-2 increases exocytosis via multiple signal transduction pathways in pancreatic duct epithelial cells","volume":"283","author":"Kim","year":"2008","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.ceca.2012.04.004_bib0075","first-page":"977","article-title":"Dog pancreatic duct epithelial cells: long-term culture and characterization","volume":"148","author":"Oda","year":"1996","journal-title":"American Journal of Pathology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0080","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/S0021-9258(19)83641-4","article-title":"A new generation of Ca2+ indicators with greatly improved fluorescence properties","volume":"260","author":"Grynkiewicz","year":"1985","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.ceca.2012.04.004_bib0085","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/S0006-3495(91)82125-7","article-title":"Single particle tracking. Analysis of diffusion and flow in two-dimensional systems","volume":"60","author":"Qian","year":"1991","journal-title":"Biophysical Journal"},{"key":"10.1016\/j.ceca.2012.04.004_bib0090","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1016\/S0006-3495(99)77382-0","article-title":"Tracking single secretory granules in live chromaffin cells by evanescent-field fluorescence microscopy","volume":"76","author":"Steyer","year":"1999","journal-title":"Biophysical Journal"},{"key":"10.1016\/j.ceca.2012.04.004_bib0095","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.cell.2010.05.008","article-title":"Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations","volume":"141","author":"Lee","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.ceca.2012.04.004_bib0100","doi-asserted-by":"crossref","first-page":"G104","DOI":"10.1152\/ajpgi.1998.275.1.G104","article-title":"Secretory effects of ATP on nontransformed dog pancreatic duct epithelial cells","volume":"275","author":"Nguyen","year":"1998","journal-title":"American Journal of Physiology. Gastrointestinal and Liver Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0105","doi-asserted-by":"crossref","first-page":"3968","DOI":"10.1104\/pp.104.049411","article-title":"A green fluorescent protein fusion to actin-binding domain 2 of Arabidopsis fimbrin highlights new features of a dynamic actin cytoskeleton in live plant cells","volume":"136","author":"Sheahan","year":"2004","journal-title":"Plant Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0110","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.ejcb.2004.11.011","article-title":"GFP-FABD2 fusion construct allows in vivo visualization of the dynamic actin cytoskeleton in all cells of Arabidopsis seedlings","volume":"84","author":"Voigt","year":"2005","journal-title":"European Journal of Cell Biology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0115","doi-asserted-by":"crossref","first-page":"4013","DOI":"10.1091\/mbc.12.12.4013","article-title":"Actin filament and Myosin I alpha cooperate with microtubules for the movement of lysosomes","volume":"12","author":"Cordonnier","year":"2001","journal-title":"Molecular Biology of the Cell"},{"key":"10.1016\/j.ceca.2012.04.004_bib0120","doi-asserted-by":"crossref","first-page":"10324","DOI":"10.1523\/JNEUROSCI.19-23-10324.1999","article-title":"Dynamics of tubulovesicular recycling endosomes in hippocampal neurons","volume":"19","author":"Prekeris","year":"1999","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.ceca.2012.04.004_bib0125","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1111\/j.1600-0854.2007.00644.x","article-title":"Moving mitochondria: establishing distribution of an essential organelle","volume":"8","author":"Frederick","year":"2007","journal-title":"Traffic"},{"key":"10.1016\/j.ceca.2012.04.004_bib0130","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1002\/glia.21000","article-title":"Intermediate filaments attenuate stimulation-dependent mobility of endosomes\/lysosomes in astrocytes","volume":"58","author":"Potokar","year":"2010","journal-title":"Glia"},{"key":"10.1016\/j.ceca.2012.04.004_bib0135","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1083\/jcb.200406038","article-title":"Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit","volume":"167","author":"Yi","year":"2004","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0140","doi-asserted-by":"crossref","first-page":"20728","DOI":"10.1073\/pnas.0808953105","article-title":"Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase","volume":"105","author":"Saotome","year":"2008","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.ceca.2012.04.004_bib0145","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.cell.2008.11.046","article-title":"The mechanism of Ca2+-dependent regulation of kinesin-mediated mitochondrial motility","volume":"136","author":"Wang","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.ceca.2012.04.004_bib0150","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.1523\/JNEUROSCI.4551-09.2010","article-title":"Activity-dependent regulaltion of mitochondrial motility by calcium and Na\/K-ATPase at nodes of Ranvier of myelinated nerves","volume":"10","author":"Zhang","year":"2010","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.ceca.2012.04.004_bib0155","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1126\/science.279.5350.509","article-title":"Rho GTPases and the actin cytoskeleton","volume":"279","author":"Hall","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.ceca.2012.04.004_bib0160","doi-asserted-by":"crossref","first-page":"7601","DOI":"10.1073\/pnas.0408546102","article-title":"Subsecond reorganization of the actin network in cell motility and chemotaxis","volume":"102","author":"Diez","year":"2005","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.ceca.2012.04.004_bib0165","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/9048","article-title":"Endocytosis vesicles move at the tips of actin tails in cultured mast cells","volume":"1","author":"Merrifield","year":"1999","journal-title":"Nature Cell Biology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0170","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1016\/S0006-3495(00)76828-7","article-title":"Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells","volume":"78","author":"Lang","year":"2000","journal-title":"Biophysical Journal"},{"key":"10.1016\/j.ceca.2012.04.004_bib0175","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1091\/mbc.e03-06-0402","article-title":"Regulated exocytosis in neuroendocrine cells: a role for subplasmalemmal Cdc42\/N-WASP-induced actin filaments","volume":"15","author":"Gasman","year":"2004","journal-title":"Molecular Biology of the Cell"},{"key":"10.1016\/j.ceca.2012.04.004_bib0180","first-page":"H1751","article-title":"P2Y1, P2Y2, P2Y4, and P2Y6 receptors are coupled to Rho and Rho kinase activation in vascular myocytes","volume":"278","author":"Sauzeau","year":"2000","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0185","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S1388-1981(01)00165-2","article-title":"Phosphoinositides, key molecules for regulation of actin cytoskeletal organization and membrane traffic from the plasma membrane","volume":"1533","author":"Takenawa","year":"2001","journal-title":"Biochimica et Biophysica Acta"},{"key":"10.1016\/j.ceca.2012.04.004_bib0190","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1146\/annurev.physiol.65.092101.142517","article-title":"Phosphoinositide regulation of the actin cytoskeleton","volume":"65","author":"Yin","year":"2003","journal-title":"Annual Review of Physiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0195","doi-asserted-by":"crossref","first-page":"3475","DOI":"10.1091\/mbc.e04-03-0218","article-title":"Rho kinase regulates the intracellular micromechanical response of adherent cells to Rho activation","volume":"15","author":"Kole","year":"2004","journal-title":"Molecular Biology of the Cell"},{"key":"10.1016\/j.ceca.2012.04.004_bib0200","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1529\/biophysj.103.026765","article-title":"Analysis of binding reactions by fluorescence recovery after photobleaching","volume":"86","author":"Sprague","year":"2004","journal-title":"Biophysical Journal"},{"key":"10.1016\/j.ceca.2012.04.004_bib0205","doi-asserted-by":"crossref","first-page":"37544","DOI":"10.1074\/jbc.M403976200","article-title":"Stabilization of exocytosis by dynamic F-actin coating of zymogen granules in pancreatic acini","volume":"279","author":"Nemoto","year":"2004","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.ceca.2012.04.004_bib0210","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0959-4388(98)80067-6","article-title":"Mitochondrial oversight of cellular Ca2+ signaling","volume":"8","author":"Babcock","year":"1998","journal-title":"Current Opinion in Neurobiology"},{"key":"10.1016\/j.ceca.2012.04.004_bib0215","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1083\/jcb.200604016","article-title":"Structural and functional features and significance of the physical linkage between ER and mitochondria","volume":"174","author":"Csordas","year":"2006","journal-title":"Journal of Cell Biology"}],"container-title":["Cell Calcium"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143416012000747?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143416012000747?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T20:13:00Z","timestamp":1758917580000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143416012000747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0143416012000747"],"URL":"https:\/\/doi.org\/10.1016\/j.ceca.2012.04.004","relation":{},"ISSN":["0143-4160"],"issn-type":[{"value":"0143-4160","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Actin cytoskeleton controls movement of intracellular organelles in pancreatic duct epithelial cells","name":"articletitle","label":"Article Title"},{"value":"Cell Calcium","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ceca.2012.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}