{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:13:36Z","timestamp":1758932016788,"version":"3.44.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"crossref","award":["2011CB944003"],"award-info":[{"award-number":["2011CB944003"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31271074","81571804"],"award-info":[{"award-number":["31271074","81571804"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Calcium"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.ceca.2015.09.001","type":"journal-article","created":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T22:03:32Z","timestamp":1441317812000},"page":"541-548","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Developmental changes in the expression and function of TRPC6 channels related the F-actin organization during differentiation in podocytes"],"prefix":"10.1016","volume":"58","author":[{"given":"Zhaowei","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajia","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaochen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengjuan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ceca.2015.09.001_bib0190","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1172\/JCI27702","article-title":"TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling","volume":"116","author":"Kuwahara","year":"2006","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.ceca.2015.09.001_bib0195","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1152\/physrev.00020.2002","article-title":"Cell biology of the glomerular podocyte","volume":"83","author":"Pavenstadt","year":"2003","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ceca.2015.09.001_bib0200","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1113\/jphysiol.2005.103143","article-title":"Human TRPC6 expressed in HEK 293 cells forms non-selective cation channels with limited Ca2+ permeability","volume":"572","author":"Estacion","year":"2006","journal-title":"J. Physiol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0205","doi-asserted-by":"crossref","first-page":"F959","DOI":"10.1152\/ajprenal.00559.2007","article-title":"The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells","volume":"295","author":"Saleem","year":"2008","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0210","doi-asserted-by":"crossref","first-page":"F473","DOI":"10.1152\/ajprenal.00425.2005","article-title":"Calcium wave of tubuloglomerular feedback","volume":"291","author":"Peti-Peterdi","year":"2006","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0215","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/ng1592","article-title":"TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function","volume":"37","author":"Reiser","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ceca.2015.09.001_bib0220","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1126\/science.1106215","article-title":"A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis","volume":"308","author":"Winn","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.ceca.2015.09.001_bib0225","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1681\/ASN.2006091010","article-title":"Induction of TRPC6 channel in acquired forms of proteinuric kidney disease","volume":"18","author":"Moller","year":"2007","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0230","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s11596-009-0405-9","article-title":"Effect of down-regulation of TRPC6 on the puromycin aminonucleoside-induced apoptosis of mouse podocytes","volume":"29","author":"Sun","year":"2009","journal-title":"J. Huazhong Univ. Sci. Technol. Med. Sci."},{"key":"10.1016\/j.ceca.2015.09.001_bib0235","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.tcb.2007.06.006","article-title":"Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton","volume":"17","author":"Faul","year":"2007","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0240","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/ng1592","article-title":"TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function","volume":"37","author":"Reiser","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ceca.2015.09.001_bib0245","doi-asserted-by":"crossref","first-page":"e38503","DOI":"10.1371\/journal.pone.0038503","article-title":"Expression of TRPC6 in renal cortex and hippocampus of mouse during postnatal development","volume":"7","author":"Xu","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ceca.2015.09.001_bib0250","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1080\/10715760802657308","article-title":"Metallothionein over-expression in podocytes reduces adriamycin nephrotoxicity","volume":"43","author":"Yang","year":"2009","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.ceca.2015.09.001_bib0255","doi-asserted-by":"crossref","first-page":"22047","DOI":"10.1074\/jbc.M402320200","article-title":"Activation of human TRPC6 channels by receptor stimulation","volume":"279","author":"Estacion","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"145","key":"10.1016\/j.ceca.2015.09.001_bib0260","doi-asserted-by":"crossref","first-page":"ra77","DOI":"10.1126\/scisignal.2001200","article-title":"Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels","volume":"3","author":"Tian","year":"2010","journal-title":"Sci. Signal."},{"key":"10.1016\/j.ceca.2015.09.001_bib0265","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ejcb.2008.10.002","article-title":"Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation","volume":"88","author":"Becker","year":"2009","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0270","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/ncb1150","article-title":"Rapid vesicular translocation and insertion of TRP channels","volume":"6","author":"Bezzerides","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0275","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.ejcb.2008.01.009","article-title":"Interplay between TRP channels and the cytoskeleton in health and disease","volume":"87","author":"Clark","year":"2008","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0280","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1111\/j.1523-1755.2005.00622.x","article-title":"Stem cells and progenitor cells in renal disease","volume":"68","author":"Haller","year":"2005","journal-title":"Kidney Int."},{"key":"10.1016\/j.ceca.2015.09.001_bib0285","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1242\/dev.001081","article-title":"Development of the renal glomerulus: good neighbors and good fences","volume":"135","author":"Quaggin","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.ceca.2015.09.001_bib0290","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1203\/PDR.0b013e3181b45565","article-title":"Characterization and culture of fetal rhesus monkey renal cortical cells","volume":"66","author":"Leapley","year":"2009","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ceca.2015.09.001_bib0295","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1681\/ASN.V85697","article-title":"Induction of differentiation in cultured rat and human podocytes","volume":"8","author":"Mundel","year":"1997","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0300","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1523-1755.2005.00387.x","article-title":"ATRA induces podocyte differentiation and alters nephrin and podocin expression in vitro and in vivo","volume":"68","author":"Vaughan","year":"2005","journal-title":"Kidney Int."},{"key":"10.1016\/j.ceca.2015.09.001_bib0305","first-page":"193","article-title":"Expression of nestin in rat and human glomerular podocytes","volume":"38","author":"Ishizaki","year":"2006","journal-title":"J. Submicrosc. Cytol. Pathol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0310","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/jnr.22805","article-title":"Voltage-dependent ionic channels in differentiating neural precursor cells collected from adult mouse brains six hours post-mortem","volume":"90","author":"Bellardita","year":"2012","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.ceca.2015.09.001_bib0315","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/16711","article-title":"Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol","volume":"397","author":"Hofmann","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.ceca.2015.09.001_bib0320","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1146\/annurev.physiol.68.040204.100431","article-title":"An introduction to TRP channels","volume":"68","author":"Ramsey","year":"2006","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0325","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.ceca.2011.03.007","article-title":"TRPC channels are involved in calcium-dependent migration and proliferation in immortalized GnRH neurons","author":"Ariano","year":"2011","journal-title":"Cell Calcium"},{"key":"10.1016\/j.ceca.2015.09.001_bib0330","doi-asserted-by":"crossref","first-page":"16586","DOI":"10.1073\/pnas.0606894103","article-title":"A common mechanism underlies stretch activation and receptor activation of TRPC6 channels","volume":"103","author":"Spassova","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ceca.2015.09.001_bib0335","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/ki.1994.47","article-title":"A role for podocytes to counteract capillary wall distension","volume":"45","author":"Kriz","year":"1994","journal-title":"Kidney Int."},{"key":"10.1016\/j.ceca.2015.09.001_bib0340","doi-asserted-by":"crossref","first-page":"17079","DOI":"10.1073\/pnas.0607465103","article-title":"Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels","volume":"103","author":"Huber","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ceca.2015.09.001_bib0345","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1124\/mol.108.051912","article-title":"Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes","volume":"75","author":"Kim","year":"2009","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0350","doi-asserted-by":"crossref","first-page":"F689","DOI":"10.1152\/ajprenal.00298.2010","article-title":"TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology","volume":"299","author":"Dryer","year":"2010","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.ceca.2015.09.001_bib0355","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s11626-013-9590-8","article-title":"Developmental changes of BK Ca channels depend on differentiation status in cultured podocytes","author":"Yang","year":"2013","journal-title":"In Vitro Cell. Dev. Biol.: Anim."},{"key":"10.1016\/j.ceca.2015.09.001_bib0360","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/74139","article-title":"Getting a foothold in nephrotic syndrome","volume":"24","author":"Somlo","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ceca.2015.09.001_bib0365","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1258\/ebm.2010.010237","article-title":"Over-expressing transient receptor potential cation channel 6 in podocytes induces cytoskeleton rearrangement through increases of intracellular Ca2+ and RhoA activation","volume":"236","author":"Jiang","year":"2011","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.ceca.2015.09.001_bib0370","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.ceca.2011.08.008","article-title":"Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes","volume":"50","author":"Chen","year":"2011","journal-title":"Cell Calcium"}],"container-title":["Cell Calcium"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143416015001451?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143416015001451?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T20:19:55Z","timestamp":1758917995000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143416015001451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0143416015001451"],"URL":"https:\/\/doi.org\/10.1016\/j.ceca.2015.09.001","relation":{},"ISSN":["0143-4160"],"issn-type":[{"type":"print","value":"0143-4160"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Developmental changes in the expression and function of TRPC6 channels related the F-actin organization during differentiation in podocytes","name":"articletitle","label":"Article Title"},{"value":"Cell Calcium","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ceca.2015.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}