{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T08:09:48Z","timestamp":1784794188536,"version":"3.55.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82570647"],"award-info":[{"award-number":["82570647"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273115"],"award-info":[{"award-number":["82273115"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Calcium"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.ceca.2026.103155","type":"journal-article","created":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T15:08:59Z","timestamp":1779548939000},"page":"103155","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Drug repurposing DMSO from an old solvent to a new candidate for the treatment of colitis and sepsis in male mice"],"prefix":"10.1016","volume":"136","author":[{"given":"Shude","family":"Pang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoya","family":"Rong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhua","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenwen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"18","key":"10.1016\/j.ceca.2026.103155_bib0001","first-page":"23027","article-title":"Cryopreservation and rapid recovery of differentiated intestinal epithelial barrier cells at complex transwell interfaces is enabled by chemically induced ice nucleation","volume":"16","author":"Bissoyi","year":"2024","journal-title":"ACS. Appl. Mater. Interfaces."},{"issue":"22","key":"10.1016\/j.ceca.2026.103155_bib0002","doi-asserted-by":"crossref","first-page":"6839","DOI":"10.3390\/molecules26226839","article-title":"Multicomponent synthesis of 2- (2, 4-Diamino-3-cyano-5H-chromeno [2, 3-b] pyridin-5-yl) malonic acids in DMSO","volume":"26","author":"Ryzhkova","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.ceca.2026.103155_bib0003","article-title":"Comparing the effect of piperine and ilepcimide on the pharmacokinetics of curcumin in SD rats","volume":"12","author":"Wang","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"6","key":"10.1016\/j.ceca.2026.103155_bib0004","doi-asserted-by":"crossref","first-page":"518","DOI":"10.3168\/jdsc.2023-0379","article-title":"Cultivation of enteroids from fresh and cryopreserved bovine duodenal tissues","volume":"4","author":"Nishihara","year":"2023","journal-title":"JDS. Commun."},{"issue":"2","key":"10.1016\/j.ceca.2026.103155_bib0005","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.vascn.2010.10.004","article-title":"Antioxidant properties of dimethyl sulfoxide and its viability as a solvent in the evaluation of neuroprotective antioxidants","volume":"63","author":"Sanmart\u00edn-Su\u00e1rez","year":"2011","journal-title":"J. Pharmacol. Toxicol. Methods"},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0006","doi-asserted-by":"crossref","first-page":"1","DOI":"10.21873\/cdp.10172","article-title":"The rationality of implementation of dimethyl sulfoxide as differentiation-inducing agent in cancer therapy","volume":"3","author":"Hoang","year":"2022","journal-title":"Cancer Diagn. Progn."},{"issue":"5","key":"10.1016\/j.ceca.2026.103155_bib0007","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/iju.14505","article-title":"Efficacy and safety of intravesical instillation of KRP-116D (50% dimethyl sulfoxide solution) for interstitial cystitis\/bladder pain syndrome in Japanese patients: a multicenter, randomized, double-blind, placebo-controlled, clinical study","volume":"28","author":"Yoshimura","year":"2021","journal-title":"Int. J. Urol."},{"issue":"2","key":"10.1016\/j.ceca.2026.103155_bib0008","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S1734-1140(09)70026-X","article-title":"Pharmacology of dimethyl sulfoxide in cardiac and CNS damage","volume":"61","author":"Jacob","year":"2009","journal-title":"Pharmacol. Rep."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0009","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0002-9610(85)80015-5","article-title":"Effect of dimethyl sulfoxide and glycerol on acute bowel ischemia in the rat","volume":"149","author":"Demetriou","year":"1985","journal-title":"Am. J. Surg."},{"issue":"5","key":"10.1016\/j.ceca.2026.103155_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e27295","article-title":"Intraventricular dimethyl sulfoxide (DMSO) induces hydrocephalus in a dose-dependent pattern","volume":"10","author":"Castaneyra-Ruiz","year":"2024","journal-title":"Heliyon."},{"issue":"2","key":"10.1016\/j.ceca.2026.103155_bib0011","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.vascn.2006.03.002","article-title":"Dimethyl sulfoxide effects on hERG channels expressed in HEK293 cells","volume":"54","author":"Du","year":"2006","journal-title":"J. Pharmacol. Toxicol. Methods"},{"issue":"3\u20134","key":"10.1016\/j.ceca.2026.103155_bib0012","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1159\/000443894","article-title":"Endothelium-dependent and -independent vasodilator effects of dimethyl sulfoxide in rat aorta","volume":"97","author":"Kaneda","year":"2016","journal-title":"Pharmacology"},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0013","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0016-5085(03)00699-1","article-title":"Acquired microvascular dysfunction in inflammatory bowel disease: loss of nitric oxide-mediated vasodilation","volume":"125","author":"Hatoum","year":"2003","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/j.ceca.2026.103155_bib0014","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/01.MIB.0000160772.78951.61","article-title":"The vasculature and inflammatory bowel disease: contribution to pathogenesis and clinical pathology","volume":"11","author":"Hatoum","year":"2005","journal-title":"Inflamm. Bowel. Dis."},{"issue":"6","key":"10.1016\/j.ceca.2026.103155_bib0015","doi-asserted-by":"crossref","first-page":"G1024","DOI":"10.1152\/ajpgi.00247.2005","article-title":"Colonic blood flow responses in experimental colitis: time course and underlying mechanisms","volume":"289","author":"Mori","year":"2005","journal-title":"Am. J. Physiol. Gastrointest. Liver. Physiol."},{"issue":"9","key":"10.1016\/j.ceca.2026.103155_bib0016","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1073\/pnas.90.9.3933","article-title":"Increased intracellular Ca2+: a critical link in the pathophysiology of sepsis?","volume":"90","author":"Song","year":"1993","journal-title":"Proc Natl Acad Sci U S A."},{"key":"10.1016\/j.ceca.2026.103155_bib0017","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jss.2020.12.016","article-title":"STIM1 Regulates endothelial calcium overload and cytokine upregulation during sepsis","volume":"263","author":"Qiu","year":"2021","journal-title":"J. Surg. Res."},{"issue":"7","key":"10.1016\/j.ceca.2026.103155_bib0018","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1097\/00003246-199907000-00031","article-title":"Microcirculatory oxygenation and shunting in sepsis and shock","volume":"27","author":"Ince","year":"1999","journal-title":"Crit. Care Med."},{"issue":"11","key":"10.1016\/j.ceca.2026.103155_bib0019","doi-asserted-by":"crossref","first-page":"3838","DOI":"10.3390\/jcm12113838","article-title":"Microcirculatory disease in patients after heart transplantation","volume":"12","author":"Iwa\u0144czyk","year":"2023","journal-title":"J. Clin. Med."},{"issue":"5","key":"10.1016\/j.ceca.2026.103155_bib0020","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/FJC.0000000000000346","article-title":"Endothelium-dependent hyperpolarization and endothelial dysfunction","volume":"67","author":"F\u00e9l\u00e9tou","year":"2016","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0021","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3390\/ijms19010315","article-title":"Endothelium-dependent hyperpolarization (EDH) in hypertension: the role of endothelial ion channels","volume":"19","author":"Goto","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0022","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/apha.12805","article-title":"Nonlinear effects of potassium channel blockers on endothelium-dependent hyperpolarization","volume":"219","author":"Coleman","year":"2017","journal-title":"Acta Physiol. (Oxf)"},{"issue":"3","key":"10.1016\/j.ceca.2026.103155_bib0023","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0959-4388(98)80056-1","article-title":"Calcium-activated potassium channels","volume":"8","author":"Vergara","year":"1998","journal-title":"Curr. Opin. Neurobiol."},{"issue":"3","key":"10.1016\/j.ceca.2026.103155_bib0024","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/sj.bjp.0702858","article-title":"Acetylcholine-induced relaxation of peripheral arteries isolated from mice lacking endothelial nitric oxide synthase","volume":"128","author":"Waldron","year":"1999","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0025","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/sj.bjp.0702300","article-title":"Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice","volume":"126","author":"Chataigneau","year":"1999","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ceca.2026.103155_bib0026","article-title":"Cyclopiazonic acid-induced Ca2+ store depletion initiates endothelium-dependent hyperpolarization-mediated vasorelaxation of mesenteric arteries in healthy and colitis mice","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Physiol."},{"issue":"3","key":"10.1016\/j.ceca.2026.103155_bib0027","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/bph.15322","article-title":"Nutrient-induced hyperosmosis evokes vasorelaxation via TRPV1 channel-mediated, endothelium-dependent, hyperpolarisation in healthy and colitis mice","volume":"178","author":"Guo","year":"2021","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ceca.2026.103155_bib0028","first-page":"1","article-title":"Trichinella spiralis excretory-secretory products protect against polymicrobial sepsis by suppressing MyD88 via mannose receptor","volume":"2014","author":"Du","year":"2014","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.ceca.2026.103155_bib0029","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.3389\/fphys.2019.01614","article-title":"Acute increase in O-GlcNAc improves survival in mice with LPS-induced systemic inflammatory Response syndrome","volume":"10","author":"Silva","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ceca.2026.103155_bib0030","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jare.2021.11.001","article-title":"Beneficial effect of capsaicin via TRPV4\/EDH signals on mesenteric arterioles of normal and colitis mice","volume":"39","author":"Zhang","year":"2022","journal-title":"J. Adv. Res."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0031","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1476-5381.1988.tb16549.x","article-title":"Amiloride analogues cause endothelium-dependent relaxation in the canine coronary artery in vitro: possible role of Na+\/Ca2+ exchange","volume":"95","author":"Cocks","year":"1988","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ceca.2026.103155_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.vph.2025.107463","article-title":"Stay connected: the myoendothelial junction proteins in vascular function and dysfunction","volume":"158","author":"Querio","year":"2025","journal-title":"Vascul. Pharmacol."},{"issue":"20","key":"10.1016\/j.ceca.2026.103155_bib0033","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1111\/bph.15607","article-title":"Endothelium-derived hydrogen sulfide acts as a hyperpolarizing factor and exerts neuroprotective effects via activation of large-conductance Ca2+-activated K+channels","volume":"178","author":"Wen","year":"2021","journal-title":"Br. J. Pharmacol."},{"issue":"17","key":"10.1016\/j.ceca.2026.103155_bib0034","doi-asserted-by":"crossref","first-page":"3297","DOI":"10.1111\/bph.14762","article-title":"Endothelial TRPV4 channels modulate vascular tone by Ca2+-induced Ca2+ release at inositol 1, 4, 5-trisphosphate receptors","volume":"176","author":"Heathcote","year":"2019","journal-title":"Br. J. Pharmacol."},{"issue":"Pt 6","key":"10.1016\/j.ceca.2026.103155_bib0035","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1242\/jcs.023903","article-title":"Ca2+-store-dependent and -independent reversal of Stim1 localization and function","volume":"121","author":"Smyth","year":"2008","journal-title":"J. Cell Sci."},{"issue":"6","key":"10.1016\/j.ceca.2026.103155_bib0036","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.ceca.2011.08.006","article-title":"Heteromeric TRPV4-C1 channels contribute to store-operated Ca(2+) entry in vascular endothelial cells","volume":"50","author":"Ma","year":"2011","journal-title":"Cell. Calcium."},{"issue":"Suppl 4","key":"10.1016\/j.ceca.2026.103155_bib0037","doi-asserted-by":"crossref","first-page":"S9","DOI":"10.1186\/cc3748","article-title":"Microvascular dysfunction as a cause of organ dysfunction in severe sepsis","volume":"9","author":"Vincent","year":"2005","journal-title":"Crit Care."},{"issue":"2","key":"10.1016\/j.ceca.2026.103155_bib0038","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.cryobiol.2016.07.006","article-title":"Dimethyl sulfoxide attenuates nitric oxide generation via modulation of cationic amino acid transporter-1 in human umbilical vein endothelial cells","volume":"73","author":"Bentur","year":"2016","journal-title":"Cryobiology"},{"key":"10.1016\/j.ceca.2026.103155_bib0039","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1749-6632.1983.tb47314.x","article-title":"Dimethyl sulfoxide inhibition of prostacyclin production in cultured aortic endothelial cells","volume":"411","author":"Alam","year":"1983","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"10","key":"10.1016\/j.ceca.2026.103155_bib0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0109432","article-title":"Upregulation of SK3 and IK1 channels contributes to the enhanced endothelial calcium signaling and the preserved coronary relaxation in obese Zucker rats","volume":"9","author":"Climent","year":"2014","journal-title":"PLoS. One"},{"issue":"5","key":"10.1016\/j.ceca.2026.103155_bib0041","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1097\/00005344-199611000-00014","article-title":"The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation","volume":"28","author":"Shimokawa","year":"1996","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"15","key":"10.1016\/j.ceca.2026.103155_bib0042","doi-asserted-by":"crossref","first-page":"3737","DOI":"10.3390\/ijms20153737","article-title":"Endothelium-dependent hyperpolarization (EDH) in diabetes: mechanistic insights and therapeutic implications","volume":"20","author":"Goto","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ceca.2026.103155_bib0043","article-title":"Estrogen receptor subtype mediated anti-inflammation and vasorelaxation via genomic and nongenomic actions in septic mice","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"2","key":"10.1016\/j.ceca.2026.103155_bib0044","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/jcp.1041560202","article-title":"The differentiation inducer, dimethyl sulfoxide, transiently increases the intracellular calcium ion concentration in various cell types","volume":"156","author":"Morley","year":"1993","journal-title":"J. Cell Physiol."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0045","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1247\/csf.14.75","article-title":"Effect of dimethyl sulfoxide on cytosolic ionized calcium concentration and cytoskeletal organization of hepatocytes in a primary culture","volume":"14","author":"Yamamoto","year":"1989","journal-title":"Cell Struct. Funct."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0046","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00418-021-01984-z","article-title":"Dimethyl sulfoxide acutely enhances regulated insulin secretion in the MIN6-K8 mouse insulinoma cell line","volume":"156","author":"Carmean","year":"2021","journal-title":"Histochem. Cell Biol."},{"issue":"12","key":"10.1016\/j.ceca.2026.103155_bib0047","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1002\/jat.4885","article-title":"Human umbilical vein endothelial Cells (HUVECs) in pharmacology and toxicology: a review","volume":"45","author":"Cao","year":"2025","journal-title":"J. Appl. Toxicol."},{"issue":"3","key":"10.1016\/j.ceca.2026.103155_bib0048","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/mam\/ozae048","article-title":"Human umbilical vein endothelial cells as a versatile cellular model system in diverse experimental paradigms: an ultrastructural perspective","volume":"30","author":"Duranova","year":"2024","journal-title":"Microsc. Microanal."},{"key":"10.1016\/j.ceca.2026.103155_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2023.122326","article-title":"Regulatory role of Piezo1 channel in endothelium-dependent hyperpolarization-mediated vasorelaxation of small resistance vessels and its anti-inflammatory action","volume":"336","author":"Rong","year":"2024","journal-title":"Life Sci."},{"issue":"2","key":"10.1016\/j.ceca.2026.103155_bib0050","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1159\/000116773","article-title":"Vascular involvement in inflammatory bowel disease: pathogenesis and clinical aspects","volume":"26","author":"Papa","year":"2008","journal-title":"Dig. Dis."},{"key":"10.1016\/j.ceca.2026.103155_bib0051","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1196\/annals.1326.003","article-title":"The intestinal microvasculature as a therapeutic target in inflammatory bowel disease","volume":"1072","author":"Hatoum","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"3","key":"10.1016\/j.ceca.2026.103155_bib0052","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0152538","article-title":"DMSO represses inflammatory cytokine production from Human blood cells and reduces autoimmune arthritis","volume":"11","author":"Elisia","year":"2016","journal-title":"PLoS. One"},{"issue":"4","key":"10.1016\/j.ceca.2026.103155_bib0053","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1248\/bpb.32.651","article-title":"The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages","volume":"32","author":"Kim","year":"2009","journal-title":"Biol. Pharm. Bull."},{"issue":"239","key":"10.1016\/j.ceca.2026.103155_bib0054","first-page":"56","article-title":"Vasoplegia in septic shock (review)","author":"Gamcrlidze","year":"2015","journal-title":"Georgian. Med. News"},{"issue":"Suppl 4","key":"10.1016\/j.ceca.2026.103155_bib0055","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.1186\/cc3753","article-title":"The microcirculation is the motor of sepsis","volume":"9","author":"Ince","year":"2005","journal-title":"Crit Care."},{"issue":"3","key":"10.1016\/j.ceca.2026.103155_bib0056","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1097\/CCM.0b013e3182742e8b","article-title":"Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome","volume":"41","author":"De Backer","year":"2013","journal-title":"Crit. Care Med."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0057","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1681\/ASN.2015111285","article-title":"Intestinal dysbiosis, barrier dysfunction, and bacterial translocation account for CKD-related systemic inflammation","volume":"28","author":"Andersen","year":"2017","journal-title":"J. Am. Soc. Nephrol."},{"issue":"4","key":"10.1016\/j.ceca.2026.103155_bib0058","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1016\/j.bbrc.2009.12.102","article-title":"DMSO inhibits human platelet activation through cyclooxygenase-1 inhibition. A novel agent for drug eluting stents?","volume":"391","author":"Asmis","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.ceca.2026.103155_bib0059","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0014-2999(98)00137-X","article-title":"Concomitant regulation of Ca2+ mobilization and G13 expression in human erythroleukemia cells","volume":"348","author":"Michel","year":"1998","journal-title":"Eur. J. Pharmacol."},{"issue":"10","key":"10.1016\/j.ceca.2026.103155_bib0060","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1182\/blood.V78.10.2534.2534","article-title":"Pertussis toxin selectively interferes with the responses of the HL-60 human promyelocytic cell line to dimethylsulfoxide","volume":"78","author":"Naccache","year":"1991","journal-title":"Blood"}],"container-title":["Cell Calcium"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143416026000485?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143416026000485?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T07:58:01Z","timestamp":1784793481000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143416026000485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":60,"alternative-id":["S0143416026000485"],"URL":"https:\/\/doi.org\/10.1016\/j.ceca.2026.103155","relation":{},"ISSN":["0143-4160"],"issn-type":[{"value":"0143-4160","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Drug repurposing DMSO from an old solvent to a new candidate for the treatment of colitis and sepsis in male mice","name":"articletitle","label":"Article Title"},{"value":"Cell Calcium","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ceca.2026.103155","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103155"}}