{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:34:00Z","timestamp":1791239640682,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":3272,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2004,8]]},"DOI":"10.1016\/j.cell.2004.08.006","type":"journal-article","created":{"date-parts":[[2004,9,27]],"date-time":"2004-09-27T16:07:09Z","timestamp":1096301229000},"page":"431-438","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":412,"title":["AID Is Required for c-myc\/IgH Chromosome Translocations In Vivo"],"prefix":"10.1016","volume":"118","author":[{"given":"Almudena R.","family":"Ramiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mila","family":"Jankovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Eisenreich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Difilippantonio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selina","family":"Chen-Kiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masamichi","family":"Muramatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tasuku","family":"Honjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Nussenzweig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel C.","family":"Nussenzweig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2004.08.006_BIB1","doi-asserted-by":"crossref","first-page":"6966","DOI":"10.1073\/pnas.79.22.6966","article-title":"Transcriptionally active DNA region that rearranges frequently in murine lymphoid tumors","volume":"79","author":"Adams","year":"1982","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB2","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1073\/pnas.80.7.1982","article-title":"Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas","volume":"80","author":"Adams","year":"1983","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB3","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/318533a0","article-title":"The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice","volume":"318","author":"Adams","year":"1985","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB4","series-title":"Harrison's Principles of Internal Medicine","first-page":"715","article-title":"Malignancies of lymphoid cells","author":"Armitage","year":"2001"},{"key":"10.1016\/j.cell.2004.08.006_BIB5","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1093\/emboj\/17.8.2404","article-title":"Ku80 is required for immunoglobulin isotype switching","volume":"17","author":"Casellas","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.cell.2004.08.006_BIB6","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1126\/science.7146913","article-title":"Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas","volume":"218","author":"Crews","year":"1982","journal-title":"Science"},{"key":"10.1016\/j.cell.2004.08.006_BIB7","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1126\/science.6401867","article-title":"Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas","volume":"219","author":"Dalla-Favera","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.cell.2004.08.006_BIB8","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1084\/jem.20020851","article-title":"Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification","volume":"196","author":"Difilippantonio","year":"2002","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2004.08.006_BIB9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/nature00981","article-title":"Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase","volume":"419","author":"Di Noia","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB10","doi-asserted-by":"crossref","first-page":"3484","DOI":"10.1093\/emboj\/18.12.3484","article-title":"Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination","volume":"18","author":"Ehrenstein","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.cell.2004.08.006_BIB11","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1073\/pnas.80.3.820","article-title":"Transcriptional activation of the translocated c-myc oncogene in Burkitt lymphoma","volume":"80","author":"Erikson","year":"1983","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB12","first-page":"333","article-title":"Chromosomal translocations in leukaemia","volume":"4","author":"Gauwerky","year":"1993","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.cell.2004.08.006_BIB13","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/304135a0","article-title":"Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene","volume":"304","author":"Hamlyn","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB14","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1073\/pnas.75.5.2140","article-title":"Organization of immunoglobulin heavy chain genes and allelic deletion model","volume":"75","author":"Honjo","year":"1978","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB15","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0092-8674(90)90248-D","article-title":"Circular DNA is excised by immunoglobulin class switch recombination","volume":"62","author":"Iwasato","year":"1990","journal-title":"Cell"},{"key":"10.1016\/j.cell.2004.08.006_BIB16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1084\/jem.190.1.21","article-title":"Different mismatch repair deficiencies all have the same effects on somatic hypermutation","volume":"190","author":"Kim","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2004.08.006_BIB17","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/386761a0","article-title":"Cancer-susceptibility genes. Gatekeepers and caretakers","volume":"386","author":"Kinzler","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB18","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1038\/sj.onc.1201409","article-title":"Deletional remodeling of c-myc-deregulating chromosomal translocations","volume":"15","author":"Kovalchuk","year":"1997","journal-title":"Oncogene"},{"key":"10.1016\/j.cell.2004.08.006_BIB19","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1038\/sj.leu.2401767","article-title":"Lymph nodes and Peyer's patches of IL-6 transgenic BALB\/c mice harbor T(12;15) translocated plasma cells that contain illegitimate exchanges between the immunoglobulin heavy-chain mu locus and c-myc","volume":"14","author":"Kovalchuk","year":"2000","journal-title":"Leukemia"},{"key":"10.1016\/j.cell.2004.08.006_BIB20","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1038\/sj.leu.2401676","article-title":"Clonal diversification of primary BALB\/c plasmacytomas harboring T(12;15) chromosomal translocations","volume":"14","author":"Kovalchuk","year":"2000","journal-title":"Leukemia"},{"key":"10.1016\/j.cell.2004.08.006_BIB21","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1073\/pnas.022643999","article-title":"IL-6 transgenic mouse model for extraosseous plasmacytoma","volume":"99","author":"Kovalchuk","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB22","doi-asserted-by":"crossref","first-page":"5580","DOI":"10.1038\/sj.onc.1204640","article-title":"Mechanisms of chromosomal translocations in B cell lymphomas","volume":"20","author":"Kuppers","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/j.cell.2004.08.006_BIB23","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1126\/science.6356357","article-title":"Translocations among antibody genes in human cancer","volume":"222","author":"Leder","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.cell.2004.08.006_BIB24","doi-asserted-by":"crossref","first-page":"4262","DOI":"10.1073\/pnas.0303971101","article-title":"Hepatitis C virus induces a mutator phenotype","volume":"101","author":"Machida","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB25","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1084\/jem.187.12.2081","article-title":"Ku70 is required for late B cell development and immunoglobulin heavy chain class switching","volume":"187","author":"Manis","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2004.08.006_BIB26","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1073\/pnas.80.2.519","article-title":"Transcriptionally active c-myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia","volume":"80","author":"Marcu","year":"1983","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB27","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0092-8674(90)90247-C","article-title":"Switch circular DNA formed in cytokine-treated mouse splenocytes","volume":"62","author":"Matsuoka","year":"1990","journal-title":"Cell"},{"key":"10.1016\/j.cell.2004.08.006_BIB28","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(92)90030-G","article-title":"RAG-1-deficient mice have no mature B and T lymphocytes","volume":"68","author":"Mombaerts","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.cell.2004.08.006_BIB29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S1074-7613(00)80241-1","article-title":"Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6","volume":"6","author":"Morse","year":"1997","journal-title":"Immunity"},{"key":"10.1016\/j.cell.2004.08.006_BIB30","doi-asserted-by":"crossref","first-page":"18470","DOI":"10.1074\/jbc.274.26.18470","article-title":"Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells","volume":"274","author":"Muramatsu","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cell.2004.08.006_BIB31","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0092-8674(00)00078-7","article-title":"Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme","volume":"102","author":"Muramatsu","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.cell.2004.08.006_BIB32","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1084\/jem.192.12.1833","article-title":"Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction","volume":"192","author":"M\u00fcschen","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2004.08.006_BIB33","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/nature727","article-title":"The AID enzyme induces class switch recombination in fibroblasts","volume":"416","author":"Okazaki","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB34","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1084\/jem.20030275","article-title":"Constitutive expression of AID leads to tumorigenesis","volume":"197","author":"Okazaki","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2004.08.006_BIB35","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/35085588","article-title":"Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas","volume":"412","author":"Pasqualucci","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB36","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/414660a","article-title":"AID is required to initiate Nbs1\/gamma-H2AX focus formation and mutations at sites of class switching","volume":"414","author":"Petersen","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB37","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/nature00862","article-title":"AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification","volume":"418","author":"Petersen-Mahrt","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB38","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1034\/j.1600-065X.2003.00061.x","article-title":"Neoplastic development in plasma cells","volume":"194","author":"Potter","year":"2003","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cell.2004.08.006_BIB39","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1093\/carcin\/13.10.1681","article-title":"Plasmacytomagenesis in mice","volume":"13","author":"Potter","year":"1992","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.cell.2004.08.006_BIB40","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/372143a0","article-title":"Chromosomal translocations in human cancer","volume":"372","author":"Rabbitts","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB41","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1016\/S0960-9822(02)01215-0","article-title":"Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice","volume":"12","author":"Rada","year":"2002","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cell.2004.08.006_BIB42","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0092-8674(00)00079-9","article-title":"Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)","volume":"102","author":"Revy","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.cell.2004.08.006_BIB43","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0167-4781(92)90134-L","article-title":"Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis","volume":"1171","author":"Rogozin","year":"1992","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cell.2004.08.006_BIB44","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S1074-7613(00)80258-7","article-title":"The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching","volume":"5","author":"Rolink","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/j.cell.2004.08.006_BIB45","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/0092-8674(92)90248-B","article-title":"V(D)J recombination","volume":"70","author":"Roth","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.cell.2004.08.006_BIB46","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0092-8674(92)90117-U","article-title":"V(D)J recombination in mouse thymocytes","volume":"69","author":"Roth","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.cell.2004.08.006_BIB47","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1084\/jem.190.3.323","article-title":"Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes","volume":"190","author":"Schrader","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2004.08.006_BIB48","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1084\/jem.20011877","article-title":"Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions","volume":"195","author":"Schrader","year":"2002","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2004.08.006_BIB49","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1126\/science.280.5370.1750","article-title":"Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes","volume":"280","author":"Shen","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.cell.2004.08.006_BIB50","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0092-8674(92)90029-C","article-title":"RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement","volume":"68","author":"Shinkai","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.cell.2004.08.006_BIB51","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/303401a0","article-title":"Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas","volume":"303","author":"Stanton","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB52","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1073\/pnas.89.1.232","article-title":"Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice","volume":"89","author":"Suematsu","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB53","doi-asserted-by":"crossref","first-page":"7837","DOI":"10.1073\/pnas.79.24.7837","article-title":"Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells","volume":"79","author":"Taub","year":"1982","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2004.08.006_BIB54","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/345452a0","article-title":"Circular DNA is a product of the immunoglobulin class switch rearrangement","volume":"345","author":"von Schwedler","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.cell.2004.08.006_BIB55","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0167-5699(97)01126-2","article-title":"Speed congenics","volume":"18","author":"Wakeland","year":"1997","journal-title":"Immunol. Today"},{"key":"10.1016\/j.cell.2004.08.006_BIB56","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1084\/jem.191.3.579","article-title":"Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3\/MSH6-deficient mice reveals a role for the MSH2\u2013MSH6 heterodimer in modulating the base substitution pattern","volume":"191","author":"Wiesendanger","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2004.08.006_BIB57","doi-asserted-by":"crossref","first-page":"4139","DOI":"10.4049\/jimmunol.159.9.4139","article-title":"Ig Sgamma3 DNA-specifc double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination","volume":"159","author":"Wuerffel","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.cell.2004.08.006_BIB58","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1126\/science.1071556","article-title":"AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts","volume":"296","author":"Yoshikawa","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.cell.2004.08.006_BIB59","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/S0092-8674(02)00770-5","article-title":"Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations","volume":"109","author":"Zhu","year":"2002","journal-title":"Cell"}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867404007524?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867404007524?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T10:50:27Z","timestamp":1758797427000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867404007524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8]]},"references-count":59,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["S0092867404007524"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2004.08.006","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2004,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"AID Is Required for c-myc\/IgH Chromosome Translocations In Vivo","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2004.08.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Cell Press. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}