{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T10:54:53Z","timestamp":1790852093787,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,7,18]],"date-time":"2014-07-18T00:00:00Z","timestamp":1405641600000},"content-version":"vor","delay-in-days":382,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.cell.2013.06.031","type":"journal-article","created":{"date-parts":[[2013,7,18]],"date-time":"2013-07-18T12:52:38Z","timestamp":1374151958000},"page":"285-296","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":253,"title":["Stacked Endoplasmic Reticulum Sheets Are Connected by Helicoidal Membrane Motifs"],"prefix":"10.1016","volume":"154","author":[{"given":"Mark","family":"Terasaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Shemesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narayanan","family":"Kasthuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin\u00a0W.","family":"Klemm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Schalek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth\u00a0J.","family":"Hayworth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur\u00a0R.","family":"Hand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Yankova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeff\u00a0W.","family":"Lichtman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom\u00a0A.","family":"Rapoport","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael\u00a0M.","family":"Kozlov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2013.06.031_bib1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0074-7696(01)05004-5","article-title":"Endoplasmic reticulum of animal cells and its organization into structural and functional domains","volume":"205","author":"Baumann","year":"2001","journal-title":"Int. Rev. Cytol."},{"key":"10.1016\/j.cell.2013.06.031_bib2","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1083\/jcb.146.2.273","article-title":"Expression of the 180-kD ribosome receptor induces membrane proliferation and increased secretory activity in yeast","volume":"146","author":"Becker","year":"1999","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cell.2013.06.031_bib3","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.1073\/pnas.1101643108","article-title":"Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes","volume":"108","author":"Bian","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2013.06.031_bib4","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1073\/pnas.1012792108","article-title":"Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1\/SPG3A","volume":"108","author":"Byrnes","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2013.06.031_bib5","doi-asserted-by":"crossref","first-page":"e38011","DOI":"10.1371\/journal.pone.0038011","article-title":"TrakEM2 software for neural circuit reconstruction","volume":"7","author":"Cardona","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cell.2013.06.031_bib6","first-page":"203","article-title":"Sur les surfaces r\u00e9gl\u00e9es dont l\u2019aire est un minimum","volume":"7","author":"Catalan","year":"1842","journal-title":"J.\u00a0Math. Pures Appl."},{"key":"10.1016\/j.cell.2013.06.031_bib7","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.1091\/mbc.E06-01-0080","article-title":"Rtn1p is involved in structuring the cortical endoplasmic reticulum","volume":"17","author":"De Craene","year":"2006","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.cell.2013.06.031_bib8","series-title":"Mathematical Models from the Collections of Universities and Museums","first-page":"44","article-title":"The helicoid","author":"do Carmo","year":"1986"},{"key":"10.1016\/j.cell.2013.06.031_bib9","series-title":"The Cell","author":"Fawcett","year":"1981"},{"key":"10.1016\/j.cell.2013.06.031_bib10","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.tcb.2011.07.004","article-title":"The ER in 3D: a multifunctional dynamic membrane network","volume":"21","author":"Friedman","year":"2011","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.cell.2013.06.031_bib11","doi-asserted-by":"crossref","first-page":"3739","DOI":"10.1021\/ma9603037","article-title":"Lamellar diblock copolymer grain boundary morphology. 3. Helicoid section twist boundary energy source","volume":"30","author":"Gido","year":"1997","journal-title":"Macromolecules"},{"key":"10.1016\/j.cell.2013.06.031_bib12","doi-asserted-by":"crossref","first-page":"4506","DOI":"10.1021\/ma00069a016","article-title":"Lamellar diblock copolymer grain-boundary morphology. 1. Twist boundary characterization","volume":"26","author":"Gido","year":"1993","journal-title":"Macromolecules"},{"key":"10.1016\/j.cell.2013.06.031_bib13","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/aja.1001350107","article-title":"The effects of acute starvation on parotid acinar cells. Ultrastructural and cytochemical observations on ad libitum-fed and starved rats","volume":"135","author":"Hand","year":"1972","journal-title":"Am. J. Anat."},{"key":"10.1016\/j.cell.2013.06.031_bib14","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1017\/S1431927606066268","article-title":"Automating the collection of ultrathin serial sections for large volume TEM reconstructions","volume":"12","author":"Hayworth","year":"2006","journal-title":"Microsc. Microanal."},{"key":"10.1016\/j.cell.2013.06.031_bib15","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1515\/znc-1973-11-1209","article-title":"Elastic properties of lipid bilayers: theory and possible experiments","volume":"28","author":"Helfrich","year":"1973","journal-title":"Z.\u00a0Naturforsch. C"},{"key":"10.1016\/j.cell.2013.06.031_bib16","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1126\/science.1153634","article-title":"Membrane proteins of the endoplasmic reticulum induce high-curvature tubules","volume":"319","author":"Hu","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.cell.2013.06.031_bib17","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.cell.2009.05.025","article-title":"A class of dynamin-like GTPases involved in the generation of the tubular ER network","volume":"138","author":"Hu","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.cell.2013.06.031_bib18","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.cell.2011.11.022","article-title":"Weaving the web of ER tubules","volume":"147","author":"Hu","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.cell.2013.06.031_bib19","first-page":"157","article-title":"Chiral lyotropic liquid crystals: TGB phases and helicoidal structures","volume":"7","author":"Kamien","year":"1997","journal-title":"J.\u00a0Phys. II"},{"key":"10.1016\/j.cell.2013.06.031_bib20","doi-asserted-by":"crossref","first-page":"6168","DOI":"10.1093\/emboj\/17.21.6168","article-title":"A novel direct interaction of endoplasmic reticulum with microtubules","volume":"17","author":"Klopfenstein","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.cell.2013.06.031_bib21","doi-asserted-by":"crossref","first-page":"3304","DOI":"10.1073\/pnas.0511137103","article-title":"Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells","volume":"103","author":"Luckey","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2013.06.031_bib22","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1083\/jcb.200201116","article-title":"Active translocon complexes labeled with GFP-Dad1 diffuse slowly as large\u00a0polysome arrays in the endoplasmic reticulum","volume":"158","author":"Nikonov","year":"2002","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cell.2013.06.031_bib23","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1242\/jcs.008979","article-title":"Climp-63-mediated binding of microtubules to the ER affects the lateral mobility of translocon complexes","volume":"120","author":"Nikonov","year":"2007","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.cell.2013.06.031_bib24","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.1091\/mbc.E06-12-1125","article-title":"p180 is involved in the interaction between the endoplasmic reticulum and microtubules through a novel microtubule-binding and bundling domain","volume":"18","author":"Ogawa-Goto","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.cell.2013.06.031_bib25","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/nature08280","article-title":"Homotypic fusion of ER membranes requires the dynamin-like GTPase atlastin","volume":"460","author":"Orso","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.cell.2013.06.031_bib26","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1083\/jcb.2.2.171","article-title":"Liver microsomes; an integrated morphological and biochemical study","volume":"2","author":"Palade","year":"1956","journal-title":"J.\u00a0Biophys. Biochem. Cytol."},{"key":"10.1016\/j.cell.2013.06.031_bib27","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1083\/jcb.2.6.671","article-title":"Pancreatic microsomes; an integrated morphological and biochemical study","volume":"2","author":"Palade","year":"1956","journal-title":"J.\u00a0Biophys. Biochem. Cytol."},{"key":"10.1016\/j.cell.2013.06.031_bib28","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/ar.1091170403","article-title":"A study in microtomy for electron microscopy","volume":"117","author":"Porter","year":"1953","journal-title":"Anat. Rec."},{"key":"10.1016\/j.cell.2013.06.031_bib29","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1091\/mbc.E10-12-0950","article-title":"Progressive sheet-to-tubule transformation is a general mechanism for endoplasmic reticulum partitioning in dividing mammalian cells","volume":"23","author":"Puhka","year":"2012","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.cell.2013.06.031_bib30","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/346540a0","article-title":"Identification of a ribosome receptor in the rough endoplasmic reticulum","volume":"346","author":"Savitz","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.cell.2013.06.031_bib31","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/(SICI)1097-0185(199807)251:3<339::AID-AR9>3.0.CO;2-Q","article-title":"Intermembrane bridges within membrane organelles revealed by quick-freeze deep-etch electron microscopy","volume":"251","author":"Senda","year":"1998","journal-title":"Anat. Rec."},{"key":"10.1016\/j.cell.2013.06.031_bib32","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.cell.2006.07.019","article-title":"Rough sheets and smooth tubules","volume":"126","author":"Shibata","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.cell.2013.06.031_bib33","doi-asserted-by":"crossref","first-page":"18892","DOI":"10.1074\/jbc.M800986200","article-title":"The reticulon and DP1\/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum","volume":"283","author":"Shibata","year":"2008","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.cell.2013.06.031_bib34","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1146\/annurev.cellbio.042308.113324","article-title":"Mechanisms shaping the membranes of cellular organelles","volume":"25","author":"Shibata","year":"2009","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.cell.2013.06.031_bib35","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.cell.2010.11.007","article-title":"Mechanisms determining the morphology of the peripheral ER","volume":"143","author":"Shibata","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.cell.2013.06.031_bib36","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.bbamcr.2005.02.001","article-title":"Golgins and GTPases, giving identity and structure to the Golgi apparatus","volume":"1744","author":"Short","year":"2005","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cell.2013.06.031_bib37","series-title":"A comprehensive introduction to differential geometry","author":"Spivak","year":"1970"},{"key":"10.1016\/j.cell.2013.06.031_bib38","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/nprot.2011.439","article-title":"High-contrast en bloc staining of neuronal tissue for field emission scanning electron microscopy","volume":"7","author":"Tapia","year":"2012","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.cell.2013.06.031_bib39","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1083\/jcb.103.4.1557","article-title":"Microtubules and the endoplasmic reticulum are highly interdependent structures","volume":"103","author":"Terasaki","year":"1986","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cell.2013.06.031_bib40","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1083\/jcb.118.5.1121","article-title":"Kinectin, a major kinesin-binding protein on ER","volume":"118","author":"Toyoshima","year":"1992","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cell.2013.06.031_bib41","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.cell.2005.11.047","article-title":"A class of membrane proteins shaping the tubular endoplasmic reticulum","volume":"124","author":"Voeltz","year":"2006","journal-title":"Cell"}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867413007708?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867413007708?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T15:10:59Z","timestamp":1563462659000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867413007708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0092867413007708"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2013.06.031","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718043569.793481135","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718043569.793481667","asserted-by":"object"}]},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stacked Endoplasmic Reticulum Sheets Are Connected by Helicoidal Membrane Motifs","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2013.06.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}