{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:53:42Z","timestamp":1792785222441,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"CAU Scientific Fund","award":["2015SKLAB6-13"],"award-info":[{"award-number":["2015SKLAB6-13"]}]},{"name":"Ministry of Science and Technology","award":["2013ZX10004608"],"award-info":[{"award-number":["2013ZX10004608"]}]},{"name":"Ministry of Science and Technology","award":["CAIJIAO(2016)273"],"award-info":[{"award-number":["CAIJIAO(2016)273"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["31071316"],"award-info":[{"award-number":["31071316"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81290342"],"award-info":[{"award-number":["81290342"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["2016YFD0500300"],"award-info":[{"award-number":["2016YFD0500300"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Task-Force of Zika Virus Research from the Chinese Academy of Sciences","award":["KJZD-EW-L15"],"award-info":[{"award-number":["KJZD-EW-L15"]}],"id":[{"id":"https:\/\/ror.org\/034t30j35","id-type":"ROR","asserted-by":"crossref"}]},{"name":"NSFC Innovative Research Group","award":["81321063"],"award-info":[{"award-number":["81321063"]}],"id":[{"id":"https:\/\/ror.org\/02v6tqw40","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.cell.2016.11.016","type":"journal-article","created":{"date-parts":[[2016,11,21]],"date-time":"2016-11-21T12:52:01Z","timestamp":1479732721000},"page":"1511-1524.e10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":336,"title":["Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice"],"prefix":"10.1016","volume":"167","author":[{"given":"Wenqiang","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuoqian","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuchun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuancheng","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinghua","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daishu","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengfeng","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangdong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George Fu","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2016.11.016_bib1","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1210\/jc.2005-2169","article-title":"Isolation and cultivation of human testicular peritubular cells: a new model for the investigation of fibrotic processes in the human testis and male infertility","volume":"91","author":"Albrecht","year":"2006","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cell.2016.11.016_bib2","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1590\/0004-282X20160035","article-title":"Guillain-Barr\u00e9 syndrome associated with the Zika virus outbreak in Brazil","volume":"74","author":"Araujo","year":"2016","journal-title":"Arq. Neuropsiquiatr."},{"key":"10.1016\/j.cell.2016.11.016_bib3","doi-asserted-by":"crossref","first-page":"940","DOI":"10.3201\/eid2205.160107","article-title":"Detection of Zika Virus in Semen","volume":"22","author":"Atkinson","year":"2016","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.cell.2016.11.016_bib4","doi-asserted-by":"crossref","first-page":"11303","DOI":"10.1073\/pnas.91.24.11303","article-title":"Germline transmission of donor haplotype following spermatogonial transplantation","volume":"91","author":"Brinster","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2016.11.016_bib5","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/ng1366","article-title":"Plzf is required in adult male germ cells for stem cell self-renewal","volume":"36","author":"Buaas","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.cell.2016.11.016_bib6","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.theriogenology.2005.04.020","article-title":"Isolation, culture and characteristics of epididymal epithelial cells from adult cats","volume":"64","author":"Buff","year":"2005","journal-title":"Theriogenology"},{"key":"10.1016\/j.cell.2016.11.016_bib7","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1016\/S0140-6736(16)00562-6","article-title":"Guillain-Barr\u00e9 Syndrome outbreak associated with Zika virus infection in French Polynesia: a\u00a0case-control study","volume":"387","author":"Cao-Lormeau","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.cell.2016.11.016_bib8","doi-asserted-by":"crossref","first-page":"341","DOI":"10.2144\/000113764","article-title":"Isolation of Sertoli, Leydig, and spermatogenic cells from the mouse testis","volume":"51","author":"Chang","year":"2011","journal-title":"Biotechniques"},{"key":"10.1016\/j.cell.2016.11.016_bib9","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/ng1367","article-title":"Essential role of Plzf in maintenance of spermatogonial stem cells","volume":"36","author":"Costoya","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.cell.2016.11.016_bib10","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1056\/NEJMc1604449","article-title":"Evidence of Sexual Transmission of Zika Virus","volume":"374","author":"D\u2019Ortenzio","year":"2016","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.cell.2016.11.016_bib11","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.chom.2016.04.013","article-title":"Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody","volume":"19","author":"Dai","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.cell.2016.11.016_bib12","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1002\/iub.1556","article-title":"Molecular basis of antibody-mediated neutralization and protection against flavivirus","volume":"68","author":"Dai","year":"2016","journal-title":"IUBMB Life"},{"key":"10.1016\/j.cell.2016.11.016_bib13","doi-asserted-by":"crossref","first-page":"372","DOI":"10.15585\/mmwr.mm6514a3","article-title":"Male-to-Male Sexual Transmission of Zika Virus--Texas, January 2016","volume":"65","author":"Deckard","year":"2016","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.cell.2016.11.016_bib14","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1126\/science.aai9137","article-title":"Rapid development of a DNA vaccine for Zika virus","volume":"354","author":"Dowd","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.cell.2016.11.016_bib15","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1021\/pr400769z","article-title":"Secretome analysis of testicular peritubular cells: a window into the human testicular microenvironment and the spermatogonial stem cell niche in man","volume":"13","author":"Flenkenthaler","year":"2014","journal-title":"J.\u00a0Proteome Res."},{"key":"10.1016\/j.cell.2016.11.016_bib16","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3201\/eid1705.101939","article-title":"Probable non-vector-borne transmission of Zika virus, Colorado, USA","volume":"17","author":"Foy","year":"2011","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.cell.2016.11.016_bib17","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1073\/pnas.0507692103","article-title":"In search of rat stem Leydig cells: identification, isolation, and lineage-specific development","volume":"103","author":"Ge","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2016.11.016_bib18","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1055\/s-0036-1592312","article-title":"Zika Virus in Semen: What We Know and What We Need to Know","volume":"34","author":"Gornet","year":"2016","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.cell.2016.11.016_bib52","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/nature20556","article-title":"Zika virus infection damages the testes in mice","volume":"540","author":"Govero","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.cell.2016.11.016_bib19","doi-asserted-by":"crossref","first-page":"i657","DOI":"10.1136\/bmj.i657","article-title":"Zika virus is a global public health emergency, declares WHO","volume":"352","author":"Gulland","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.cell.2016.11.016_bib20","doi-asserted-by":"crossref","first-page":"215","DOI":"10.15585\/mmwr.mm6508e2","article-title":"Transmission of Zika Virus Through Sexual Contact with Travelers to Areas of Ongoing Transmission - Continental United States, 2016","volume":"65","author":"Hills","year":"2016","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.cell.2016.11.016_bib21","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1073\/pnas.022646399","article-title":"Adenovirus-mediated gene delivery and in\u00a0vitro microinsemination produce offspring from infertile male mice","volume":"99","author":"Kanatsu-Shinohara","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2016.11.016_bib22","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1387\/ijdb.092874gk","article-title":"Dicer is required for Sertoli cell function and survival","volume":"54","author":"Kim","year":"2010","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.cell.2016.11.016_bib23","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1095\/biolreprod36.3.769","article-title":"Effect of luteinizing hormone deprivation in\u00a0situ on steroidogenesis of rat Leydig cells purified by a multistep procedure","volume":"36","author":"Klinefelter","year":"1987","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cell.2016.11.016_bib24","doi-asserted-by":"crossref","first-page":"E1227","DOI":"10.1210\/jc.2013-4199","article-title":"Human testicular peritubular cells host putative stem Leydig cells with steroidogenic capacity","volume":"99","author":"Landreh","year":"2014","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cell.2016.11.016_bib25","doi-asserted-by":"crossref","first-page":"4864","DOI":"10.1128\/JVI.00252-16","article-title":"Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere","volume":"90","author":"Lazear","year":"2016","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2016.11.016_bib26","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.chom.2016.03.010","article-title":"A Mouse Model of Zika Virus Pathogenesis","volume":"19","author":"Lazear","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.cell.2016.11.016_bib28","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nri3787","article-title":"Type I interferons in infectious disease","volume":"15","author":"McNab","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cell.2016.11.016_bib29","doi-asserted-by":"crossref","first-page":"359","DOI":"10.3201\/eid2102.141363","article-title":"Potential sexual transmission of Zika virus","volume":"21","author":"Musso","year":"2015","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.cell.2016.11.016_bib30","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ijid.2016.02.017","article-title":"Transmission potential of Zika virus infection in the South Pacific","volume":"45","author":"Nishiura","year":"2016","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.cell.2016.11.016_bib31","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.stem.2016.03.012","article-title":"Expression analysis highlights AXL as a candidate Zika virus entry receptor in neural stem cells","volume":"18","author":"Nowakowski","year":"2016","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.cell.2016.11.016_bib32","first-page":"111","article-title":"Transplantation of testis germinal cells into mouse seminiferous tubules","volume":"41","author":"Ogawa","year":"1997","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.cell.2016.11.016_bib33","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/71496","article-title":"Transplantation of male germ line stem cells restores fertility in infertile mice","volume":"6","author":"Ogawa","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.cell.2016.11.016_bib34","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/sj.cr.7290309","article-title":"The host type I interferon response to viral and bacterial infections","volume":"15","author":"Perry","year":"2005","journal-title":"Cell Res."},{"key":"10.1016\/j.cell.2016.11.016_bib35","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1056\/NEJMsr1604338","article-title":"Zika Virus and Birth Defects--Reviewing the Evidence for Causality","volume":"374","author":"Rasmussen","year":"2016","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.cell.2016.11.016_bib36","doi-asserted-by":"crossref","first-page":"4544","DOI":"10.1182\/blood.V86.12.4544.bloodjournal86124544","article-title":"Leukemia translocation gene, PLZF, is expressed with a speckled nuclear pattern in early hematopoietic progenitors","volume":"86","author":"Reid","year":"1995","journal-title":"Blood"},{"key":"10.1016\/j.cell.2016.11.016_bib37","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/j.1439-0272.1978.tb03068.x","article-title":"Leydig cells within the lamina propria of seminiferous tubules in four patients with azoospermia","volume":"10","author":"Schulze","year":"1978","journal-title":"Andrologia"},{"key":"10.1016\/j.cell.2016.11.016_bib38","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1210\/en.2011-0031","article-title":"Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells","volume":"152","author":"Shang","year":"2011","journal-title":"Endocrinology"},{"key":"10.1016\/j.cell.2016.11.016_bib39","doi-asserted-by":"crossref","first-page":"e68","DOI":"10.1038\/emi.2016.68","article-title":"Increasing genetic diversity of Zika virus in the Latin American outbreak","volume":"5","author":"Shi","year":"2016","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.cell.2016.11.016_bib40","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1093\/humrep\/deq170","article-title":"Glial cell line-derived neurotrophic factor is constitutively produced by human testicular peritubular cells and may contribute to the spermatogonial stem cell niche in man","volume":"25","author":"Spinnler","year":"2010","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.cell.2016.11.016_bib41","first-page":"1421","article-title":"Evaluation and treatment of hematospermia","volume":"80","author":"Stefanovic","year":"2009","journal-title":"Am. Fam. Physician"},{"key":"10.1016\/j.cell.2016.11.016_bib42","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.stem.2016.02.016","article-title":"Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth","volume":"18","author":"Tang","year":"2016","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.cell.2016.11.016_bib43","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1095\/biolreprod42.2.351","article-title":"Characterization of rat testicular peritubular myoid cells in culture: alpha-smooth muscle isoactin is a specific differentiation marker","volume":"42","author":"Tung","year":"1990","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cell.2016.11.016_bib44","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1210\/endo-123-4-2100","article-title":"Testicular peritubular cells secrete a protein under androgen control that inhibits induction of aromatase activity in Sertoli cells","volume":"123","author":"Verhoeven","year":"1988","journal-title":"Endocrinology"},{"key":"10.1016\/j.cell.2016.11.016_bib46","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1360\/N972016-00665","article-title":"Genetic and biological characterization of Zika virus from human cases imported through Shenzhen Port","volume":"61","author":"Wang","year":"2016","journal-title":"Chin. Sci. Bull."},{"key":"10.1016\/j.cell.2016.11.016_bib47","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jinf.2016.06.008","article-title":"A family cluster of imported ZIKV cases: Viremia period may be longer than previously reported","volume":"73","author":"Wu","year":"2016","journal-title":"J.\u00a0Infect."},{"key":"10.1016\/j.cell.2016.11.016_bib48","doi-asserted-by":"crossref","first-page":"19507","DOI":"10.1038\/srep19507","article-title":"Mumps virus-induced innate immune responses in mouse Sertoli and Leydig cells","volume":"6","author":"Wu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cell.2016.11.016_bib49","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1172\/JCI59901","article-title":"Estrogen promotes Leydig cell engulfment by macrophages in male infertility","volume":"124","author":"Yu","year":"2014","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.cell.2016.11.016_bib50","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s13238-016-0274-5","article-title":"Highly diversified Zika viruses imported to China, 2016","volume":"7","author":"Zhang","year":"2016","journal-title":"Protein Cell"},{"key":"10.1016\/j.cell.2016.11.016_bib51","doi-asserted-by":"crossref","first-page":"4825","DOI":"10.4049\/jimmunol.1402706","article-title":"Pattern recognition receptor-initiated innate antiviral responses in mouse epididymal epithelial cells","volume":"194","author":"Zhu","year":"2015","journal-title":"J.\u00a0Immunol."}],"updated-by":[{"DOI":"10.1016\/j.cell.2017.01.009","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:00:00Z","timestamp":1485388800000}}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867416315379?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867416315379?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T11:26:35Z","timestamp":1758799595000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867416315379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":50,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0092867416315379"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2016.11.016","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.727022281.793542618","asserted-by":"object"}]},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2016.11.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}