{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T11:00:04Z","timestamp":1778756404755,"version":"3.51.4"},"reference-count":7,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"vor","delay-in-days":384,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.cell.2018.08.068","type":"journal-article","created":{"date-parts":[[2018,9,20]],"date-time":"2018-09-20T10:51:06Z","timestamp":1537440666000},"page":"38-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Chromatin Domains Go on Repeat in Disease"],"prefix":"10.1016","volume":"175","author":[{"given":"Benoit G.","family":"Bruneau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elph\u00e8ge P.","family":"Nora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2018.08.068_bib1","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.cell.2017.06.034","article-title":"Genome Organization Drives Chromosome Fragility","volume":"170","author":"Canela","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.cell.2018.08.068_bib2","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature11082","article-title":"Topological domains in mammalian genomes identified by analysis of chromatin interactions","volume":"485","author":"Dixon","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.cell.2018.08.068_bib3","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1126\/science.aad9024","article-title":"Activation of proto-oncogenes by disruption of chromosome neighborhoods","volume":"351","author":"Hnisz","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.cell.2018.08.068_bib4","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.cell.2018.01.012","article-title":"Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene","volume":"172","author":"Liu","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.cell.2018.08.068_bib5","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.cell.2015.04.004","article-title":"Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions","volume":"161","author":"Lupi\u00e1\u00f1ez","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.cell.2018.08.068_bib6","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/nature11049","article-title":"Spatial partitioning of the regulatory landscape of the X-inactivation centre","volume":"485","author":"Nora","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.cell.2018.08.068_bib7","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.cell.2018.08.005","article-title":"Disease-Associated Short Tandem Repeats Co-localize with Chromatin Domain Boundaries","volume":"175","author":"Sun","year":"2018","journal-title":"Cell"}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867418311693?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867418311693?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T11:32:05Z","timestamp":1758799925000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867418311693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S0092867418311693"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2018.08.068","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chromatin Domains Go on Repeat in Disease","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2018.08.068","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2018.08.005","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}