{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:51:30Z","timestamp":1790815890204,"version":"4.1.0"},"reference-count":79,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,30]],"date-time":"2020-05-30T00:00:00Z","timestamp":1590796800000},"content-version":"vor","delay-in-days":395,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004739","name":"Youth Innovation Promotion Association of the Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["2018113"],"award-info":[{"award-number":["2018113"]}],"id":[{"id":"10.13039\/501100004739","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDB29010000"],"award-info":[{"award-number":["XDB29010000"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7184208"],"award-info":[{"award-number":["7184208"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2015ZX09102024"],"award-info":[{"award-number":["2015ZX09102024"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81621091"],"award-info":[{"award-number":["81621091"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31430025"],"award-info":[{"award-number":["31430025"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81601766"],"award-info":[{"award-number":["81601766"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009592","name":"Beijing Municipal Science and Technology Commission","doi-asserted-by":"publisher","award":["Z181100001318009"],"award-info":[{"award-number":["Z181100001318009"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2016YFC1200304"],"award-info":[{"award-number":["2016YFC1200304"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012659","name":"Foundation for Innovative Research Groups of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.cell.2019.04.035","type":"journal-article","created":{"date-parts":[[2019,5,16]],"date-time":"2019-05-16T10:49:14Z","timestamp":1558003754000},"page":"1553-1565.e16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":126,"title":["Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B"],"prefix":"10.1016","volume":"177","author":[{"given":"Xin","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guigen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangpeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchao","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianpan","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengrong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changyao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zifang","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meifan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxun","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhai","family":"Bi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinghua","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengde","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wensheng","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George F.","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2019.04.035_bib1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.15585\/mmwr.mm6718a2","article-title":"Enterovirus and Parechovirus Surveillance - United States, 2014-2016","volume":"67","author":"Abedi","year":"2018","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"issue":"Suppl 1","key":"10.1016\/j.cell.2019.04.035_bib2","doi-asserted-by":"crossref","first-page":"S108","DOI":"10.1016\/j.jinf.2013.09.020","article-title":"The enteroviruses: problems in need of treatments","volume":"68","author":"Abzug","year":"2014","journal-title":"J.\u00a0Infect."},{"key":"10.1016\/j.cell.2019.04.035_bib3","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1107\/S0907444909052925","article-title":"PHENIX: a comprehensive Python-based system for macromolecular structure solution","volume":"66","author":"Adams","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.cell.2019.04.035_bib4","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1073\/pnas.1713284115","article-title":"Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus","volume":"115","author":"Baggen","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2019.04.035_bib5","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/978-1-4614-7651-1_2","article-title":"Picornavirus entry","volume":"790","author":"Bergelson","year":"2013","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.cell.2019.04.035_bib6","doi-asserted-by":"crossref","first-page":"6847","DOI":"10.1128\/jvi.67.11.6847-6852.1993","article-title":"Infection by echoviruses 1 and 8 depends on the alpha 2 subunit of human VLA-2","volume":"67","author":"Bergelson","year":"1993","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib7","doi-asserted-by":"crossref","first-page":"6245","DOI":"10.1073\/pnas.91.13.6245","article-title":"Decay-accelerating factor (CD55), a glycosylphosphatidylinositol-anchored complement regulatory protein, is a receptor for several echoviruses","volume":"91","author":"Bergelson","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2019.04.035_bib8","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1126\/science.275.5304.1320","article-title":"Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5","volume":"275","author":"Bergelson","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.cell.2019.04.035_bib9","doi-asserted-by":"crossref","first-page":"8325","DOI":"10.1074\/jbc.M311334200","article-title":"The structure of echovirus type 12 bound to a two-domain fragment of its cellular attachment protein decay-accelerating factor (CD 55)","volume":"279","author":"Bhella","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.cell.2019.04.035_bib10","doi-asserted-by":"crossref","first-page":"e168","DOI":"10.1093\/nar\/gku936","article-title":"Easy quantitative assessment of genome editing by sequence trace decomposition","volume":"42","author":"Brinkman","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2019.04.035_bib11","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/nsmb955","article-title":"Cryo-electron microscopy reconstruction of a poliovirus-receptor-membrane complex","volume":"12","author":"Bubeck","year":"2005","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.cell.2019.04.035_bib12","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1107\/S0907444909042073","article-title":"MolProbity: all-atom structure validation for macromolecular crystallography","volume":"66","author":"Chen","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.cell.2019.04.035_bib13","doi-asserted-by":"crossref","first-page":"e54","DOI":"10.1038\/emi.2017.39","article-title":"An outbreak of echovirus 18 encephalitis\/meningitis in children in Hebei Province, China, 2015","volume":"6","author":"Chen","year":"2017","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.cell.2019.04.035_bib14","article-title":"Echovirus Infection","author":"Choudhary","year":"2017","journal-title":"eMedicine"},{"key":"10.1016\/j.cell.2019.04.035_bib15","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1134\/S0026893312050032","article-title":"[Oncolytic enteroviruses]","volume":"46","author":"Chumakov","year":"2012","journal-title":"Mol. Biol. (Mosk.)"},{"key":"10.1016\/j.cell.2019.04.035_bib16","first-page":"1228","article-title":"Aseptic meningitis outbreak associated with echovirus 30 among high school football players--Los Angeles County, California, 2014","volume":"63","author":"Croker","year":"2015","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.cell.2019.04.035_bib17","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1126\/science.122.3181.1187","article-title":"ENTERIC cytopathogenic human orphan (ECHO) viruses","volume":"122","author":"Dalldorf","year":"1955","journal-title":"Science"},{"key":"10.1016\/j.cell.2019.04.035_bib18","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/CMR.0000000000000180","article-title":"Adapted ECHO-7 virus Rigvir immunotherapy (oncolytic virotherapy) prolongs survival in melanoma patients after surgical excision of the tumour in a retrospective study","volume":"25","author":"Doni\u0146a","year":"2015","journal-title":"Melanoma Res."},{"key":"10.1016\/j.cell.2019.04.035_bib19","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1107\/S0907444910007493","article-title":"Features and development of Coot","volume":"66","author":"Emsley","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.cell.2019.04.035_bib20","doi-asserted-by":"crossref","first-page":"e1006197","DOI":"10.1371\/journal.ppat.1006197","article-title":"Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes","volume":"13","author":"Groppelli","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.cell.2019.04.035_bib21","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s00109-008-0433-0","article-title":"Regional administration of oncolytic Echovirus 1 as a novel therapy for the peritoneal dissemination of gastric cancer","volume":"87","author":"Haley","year":"2009","journal-title":"J.\u00a0Mol. Med. (Berl.)"},{"key":"10.1016\/j.cell.2019.04.035_bib22","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1073\/pnas.97.1.79","article-title":"Interaction of the poliovirus receptor with poliovirus","volume":"97","author":"He","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2019.04.035_bib23","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1038\/nsb1001-874","article-title":"Interaction of coxsackievirus B3 with the full length coxsackievirus-adenovirus receptor","volume":"8","author":"He","year":"2001","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.cell.2019.04.035_bib24","doi-asserted-by":"crossref","first-page":"10325","DOI":"10.1073\/pnas.152161599","article-title":"Structure of decay-accelerating factor bound to echovirus 7: a virus-receptor complex","volume":"99","author":"He","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2019.04.035_bib25","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.1128\/JVI.01340-09","article-title":"Internalization of coxsackievirus A9 is mediated by beta2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin","volume":"84","author":"Heikkil\u00e4","year":"2010","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib26","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jcv.2016.06.007","article-title":"Predominance of enterovirus B and echovirus 30 as cause of viral meningitis in a UK population","volume":"81","author":"Holmes","year":"2016","journal-title":"J.\u00a0Clin. Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib27","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1002\/jmv.24200","article-title":"Characterization of severe hand, foot, and mouth disease in Shenzhen, China, 2009-2013","volume":"87","author":"Huang","year":"2015","journal-title":"J.\u00a0Med. Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib28","doi-asserted-by":"crossref","first-page":"15906","DOI":"10.1073\/pnas.2535934100","article-title":"Transgenic mouse model for echovirus myocarditis and paralysis","volume":"100","author":"Hughes","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2019.04.035_bib29","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1186\/1743-422X-8-473","article-title":"Cytolytic replication of echoviruses in colon cancer cell lines","volume":"8","author":"Israelsson","year":"2011","journal-title":"Virol. J."},{"key":"10.1016\/j.cell.2019.04.035_bib30","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jinf.2014.05.012","article-title":"Seven-fold increase in viral meningo-encephalitis reports in England and Wales during 2004-2013","volume":"69","author":"Kadambari","year":"2014","journal-title":"J.\u00a0Infect."},{"key":"10.1016\/j.cell.2019.04.035_bib31","first-page":"1","article-title":"Enterovirus surveillance--United States, 1970-2005","volume":"55","author":"Khetsuriani","year":"2006","journal-title":"MMWR Surveill. Summ."},{"key":"10.1016\/j.cell.2019.04.035_bib32","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1743-422X-9-38","article-title":"Epidemics of viral meningitis caused by echovirus 6 and 30 in Korea in 2008","volume":"9","author":"Kim","year":"2012","journal-title":"Virol. J."},{"key":"10.1016\/j.cell.2019.04.035_bib33","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1186\/s13059-014-0554-4","article-title":"MAGeCK enables robust identification of essential genes from genome-scale CRISPR\/Cas9 knockout screens","volume":"15","author":"Li","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.cell.2019.04.035_bib34","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/nature12328","article-title":"Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26","volume":"500","author":"Lu","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.cell.2019.04.035_bib35","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1002\/jmv.21707","article-title":"An aseptic meningitis outbreak caused by echovirus 6 in Anhui province, China","volume":"82","author":"Mao","year":"2010","journal-title":"J.\u00a0Med. Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib36","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1128\/JVI.76.4.1856-1865.2002","article-title":"Internalization of echovirus 1 in caveolae","volume":"76","author":"Marjom\u00e4ki","year":"2002","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib37","doi-asserted-by":"crossref","first-page":"6387","DOI":"10.3390\/v7122945","article-title":"Infectious Entry Pathway of Enterovirus B Species","volume":"7","author":"Marjom\u00e4ki","year":"2015","journal-title":"Viruses"},{"key":"10.1016\/j.cell.2019.04.035_bib38","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1006\/viro.2000.0324","article-title":"The coxsackie-adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B and by swine vesicular disease virus","volume":"271","author":"Martino","year":"2000","journal-title":"Virology"},{"key":"10.1016\/j.cell.2019.04.035_bib39","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0092-8674(89)90690-9","article-title":"Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily","volume":"56","author":"Mendelsohn","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.cell.2019.04.035_bib40","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/nm.1961","article-title":"Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71","volume":"15","author":"Nishimura","year":"2009","journal-title":"Nat. Med."},{"key":"10.1016\/j.cell.2019.04.035_bib41","doi-asserted-by":"crossref","first-page":"7812","DOI":"10.1074\/jbc.M113.537563","article-title":"Structural insights into neonatal Fc receptor-based recycling mechanisms","volume":"289","author":"Oganesyan","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.cell.2019.04.035_bib42","doi-asserted-by":"crossref","first-page":"5755","DOI":"10.1128\/JVI.00299-14","article-title":"Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the A-particle","volume":"88","author":"Organtini","year":"2014","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib43","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1111\/febs.13251","article-title":"High-throughput screens in mammalian cells using the CRISPR-Cas9 system","volume":"282","author":"Peng","year":"2015","journal-title":"FEBS J."},{"key":"10.1016\/j.cell.2019.04.035_bib44","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/jcc.20084","article-title":"UCSF Chimera--a visualization system for exploratory research and analysis","volume":"25","author":"Pettersen","year":"2004","journal-title":"J.\u00a0Comput. Chem."},{"key":"10.1016\/j.cell.2019.04.035_bib45","doi-asserted-by":"crossref","first-page":"12665","DOI":"10.1128\/JVI.00837-10","article-title":"Interaction of decay-accelerating factor with echovirus 7","volume":"84","author":"Plevka","year":"2010","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib46","doi-asserted-by":"crossref","first-page":"9306","DOI":"10.1128\/jvi.71.12.9306-9312.1997","article-title":"Interaction between echovirus 7 and its receptor, decay-accelerating factor (CD55): evidence for a secondary cellular factor in A-particle formation","volume":"71","author":"Powell","year":"1997","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib47","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.virusres.2011.03.009","article-title":"Development of a recombinant CHO cell model for the investigation of CAR and DAF role during early steps of echovirus 6 infection","volume":"158","author":"Renois","year":"2011","journal-title":"Virus Res."},{"key":"10.1016\/j.cell.2019.04.035_bib48","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jsb.2015.08.008","article-title":"CTFFIND4: Fast and accurate defocus estimation from electron micrographs","volume":"192","author":"Rohou","year":"2015","journal-title":"J.\u00a0Struct. Biol."},{"key":"10.1016\/j.cell.2019.04.035_bib49","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/nri2155","article-title":"FcRn: the neonatal Fc receptor comes of age","volume":"7","author":"Roopenian","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cell.2019.04.035_bib50","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0966-842X(02)02383-1","article-title":"Picornavirus-receptor interactions","volume":"10","author":"Rossmann","year":"2002","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.cell.2019.04.035_bib51","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/nmeth.3047","article-title":"Improved vectors and genome-wide libraries for CRISPR screening","volume":"11","author":"Sanjana","year":"2014","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2019.04.035_bib52","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jsb.2012.09.006","article-title":"RELION: implementation of a Bayesian approach to cryo-EM structure determination","volume":"180","author":"Scheres","year":"2012","journal-title":"J.\u00a0Struct. Biol."},{"key":"10.1016\/j.cell.2019.04.035_bib53","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1046\/j.1471-4159.2002.00840.x","article-title":"Expression of the neonatal Fc receptor (FcRn) at the blood-brain barrier","volume":"81","author":"Schlachetzki","year":"2002","journal-title":"J.\u00a0Neurochem."},{"key":"10.1016\/j.cell.2019.04.035_bib54","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/ijc.20866","article-title":"Oncolysis of human ovarian cancers by echovirus type 1","volume":"115","author":"Shafren","year":"2005","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.cell.2019.04.035_bib55","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.1128\/JVI.02989-12","article-title":"Structural and functional analysis of coxsackievirus A9 integrin \u03b1v\u03b26 binding and uncoating","volume":"87","author":"Shakeel","year":"2013","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib56","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.chom.2018.03.019","article-title":"KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses","volume":"23","author":"Staring","year":"2018","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.cell.2019.04.035_bib57","doi-asserted-by":"crossref","first-page":"3903","DOI":"10.1128\/JVI.03209-12","article-title":"RNA transfer from poliovirus 135S particles across membranes is mediated by long umbilical connectors","volume":"87","author":"Strauss","year":"2013","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib58","doi-asserted-by":"crossref","first-page":"4143","DOI":"10.1128\/JVI.03101-14","article-title":"Nectin-like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry","volume":"89","author":"Strauss","year":"2015","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib59","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"Tamura","year":"2011","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.cell.2019.04.035_bib60","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jsb.2006.05.009","article-title":"EMAN2: an extensible image processing suite for electron microscopy","volume":"157","author":"Tang","year":"2007","journal-title":"J.\u00a0Struct. Biol."},{"key":"10.1016\/j.cell.2019.04.035_bib61","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.7150\/jca.23242","article-title":"Effect of the oncolytic ECHO-7 virus Rigvir\u00ae on the viability of cell lines of human origin in\u00a0vitro","volume":"9","author":"Tilgase","year":"2018","journal-title":"J.\u00a0Cancer"},{"key":"10.1016\/j.cell.2019.04.035_bib62","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1128\/JVI.80.1.172-180.2006","article-title":"Characterization of early steps in the poliovirus infection process: receptor-decorated liposomes induce conversion of the virus to membrane-anchored entry-intermediate\u00a0particles","volume":"80","author":"Tuthill","year":"2006","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib63","first-page":"43","article-title":"Picornaviruses","volume":"343","author":"Tuthill","year":"2010","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.cell.2019.04.035_bib64","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1038\/nsmb.2255","article-title":"A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71","volume":"19","author":"Wang","year":"2012","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.cell.2019.04.035_bib65","doi-asserted-by":"crossref","first-page":"5070","DOI":"10.1002\/j.1460-2075.1994.tb06836.x","article-title":"Decay-accelerating factor CD55 is identified as the receptor for echovirus 7 using CELICS, a rapid immuno-focal cloning method","volume":"13","author":"Ward","year":"1994","journal-title":"EMBO J."},{"key":"10.1016\/j.cell.2019.04.035_bib66","doi-asserted-by":"crossref","first-page":"5360","DOI":"10.1128\/JVI.72.7.5360-5365.1998","article-title":"Role for beta2-microglobulin in echovirus infection of rhabdomyosarcoma cells","volume":"72","author":"Ward","year":"1998","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib67","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/nrmicro1284","article-title":"Host and virus determinants of picornavirus pathogenesis and tropism","volume":"3","author":"Whitton","year":"2005","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.cell.2019.04.035_bib68","doi-asserted-by":"crossref","first-page":"6967","DOI":"10.1128\/JVI.78.13.6967-6973.2004","article-title":"Integrin alpha v beta 6 is an RGD-dependent receptor for coxsackievirus A9","volume":"78","author":"Williams","year":"2004","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib69","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1128\/JVI.75.5.2444-2451.2001","article-title":"Interaction of coxsackievirus A21 with its cellular receptor, ICAM-1","volume":"75","author":"Xiao","year":"2001","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib70","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.str.2005.04.011","article-title":"The crystal structure of coxsackievirus A21 and its interaction with ICAM-1","volume":"13","author":"Xiao","year":"2005","journal-title":"Structure"},{"key":"10.1016\/j.cell.2019.04.035_bib71","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1038\/nm.1992","article-title":"Scavenger receptor B2 is a cellular receptor for enterovirus 71","volume":"15","author":"Yamayoshi","year":"2009","journal-title":"Nat. Med."},{"key":"10.1016\/j.cell.2019.04.035_bib72","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3390\/v8030057","article-title":"Therapeutic Use of Native and Recombinant Enteroviruses","volume":"8","author":"Yl\u00e4-Pelto","year":"2016","journal-title":"Viruses"},{"key":"10.1016\/j.cell.2019.04.035_bib73","doi-asserted-by":"crossref","first-page":"12571","DOI":"10.1128\/JVI.01592-12","article-title":"The crystal structure of a coxsackievirus B3-RD variant and a refined 9-angstrom cryo-electron microscopy reconstruction of the virus complexed with decay-accelerating factor (DAF) provide a new footprint of DAF on the virus surface","volume":"86","author":"Yoder","year":"2012","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.cell.2019.04.035_bib74","doi-asserted-by":"crossref","first-page":"18284","DOI":"10.1073\/pnas.0807848105","article-title":"Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses","volume":"105","author":"Zhang","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2019.04.035_bib75","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/s41586-018-0121-3","article-title":"Mxra8 is a receptor for multiple arthritogenic alphaviruses","volume":"557","author":"Zhang","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.cell.2019.04.035_bib76","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/nmeth.4193","article-title":"MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy","volume":"14","author":"Zheng","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2019.04.035_bib77","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/nature13166","article-title":"High-throughput screening of a CRISPR\/Cas9 library for functional genomics in human cells","volume":"509","author":"Zhou","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.cell.2019.04.035_bib78","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1186\/s40064-016-3194-1","article-title":"Molecular identification of human enteroviruses associated with aseptic meningitis in Yunnan province, Southwest China","volume":"5","author":"Zhu","year":"2016","journal-title":"Springerplus"},{"key":"10.1016\/j.cell.2019.04.035_bib79","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/978-1-4939-7237-1_11","article-title":"Genome-Wide CRISPR\/Cas9 Screening for High-Throughput Functional Genomics in Human Cells","volume":"1656","author":"Zhu","year":"2017","journal-title":"Methods Mol. Biol."}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867419304544?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867419304544?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:10:46Z","timestamp":1777475446000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867419304544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":79,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["S0092867419304544"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2019.04.035","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2019.04.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}