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Dermatol."},{"key":"10.1016\/j.cell.2021.06.004_bib67","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.micinf.2004.07.002","article-title":"CD28 is required for T\u00a0cell activation and IFN-gamma production by CD4+ and CD8+ T\u00a0cells in response to Trypanosoma cruzi infection","volume":"6","author":"Martins","year":"2004","journal-title":"Microbes Infect."},{"key":"10.1016\/j.cell.2021.06.004_bib68","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cels.2019.03.003","article-title":"DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors","volume":"8","author":"McGinnis","year":"2019","journal-title":"Cell Syst."},{"key":"10.1016\/j.cell.2021.06.004_bib69","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1101\/gr.107524.110","article-title":"The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data","volume":"20","author":"McKenna","year":"2010","journal-title":"Genome Res."},{"key":"10.1016\/j.cell.2021.06.004_bib70","doi-asserted-by":"crossref","first-page":"e1000091","DOI":"10.1371\/journal.ppat.1000091","article-title":"Seroprevalence of 34 human papillomavirus types in the German general population","volume":"4","author":"Michael","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.cell.2021.06.004_bib71","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1126\/science.aay6485","article-title":"Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens","volume":"366","author":"Mina","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.cell.2021.06.004_bib72","doi-asserted-by":"crossref","first-page":"6769","DOI":"10.4049\/jimmunol.163.12.6769","article-title":"Critical role of CD28 in protective immunity against Salmonella typhimurium","volume":"163","author":"Mittr\u00fccker","year":"1999","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.cell.2021.06.004_bib73","doi-asserted-by":"crossref","first-page":"5620","DOI":"10.4049\/jimmunol.167.10.5620","article-title":"Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes","volume":"167","author":"Mittr\u00fccker","year":"2001","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.cell.2021.06.004_bib74","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1038\/s41596-018-0088-4","article-title":"Publisher Correction: PhIP-Seq characterization of serum antibodies using oligonucleotide-encoded peptidomes","volume":"14","author":"Mohan","year":"2019","journal-title":"Nat. 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Chem."},{"key":"10.1016\/j.cell.2021.06.004_bib106","doi-asserted-by":"crossref","first-page":"6919","DOI":"10.1093\/nar\/gkv613","article-title":"The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80","volume":"43","author":"Typas","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2021.06.004_bib107","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1002\/ccr3.1595","article-title":"An ANKRD26 nonsense somatic mutation in a female with epidermodysplasia verruciformis (Tree Man Syndrome)","volume":"6","author":"Uddin","year":"2018","journal-title":"Clin. Case Rep."},{"key":"10.1016\/j.cell.2021.06.004_bib108","doi-asserted-by":"crossref","first-page":"D571","DOI":"10.1093\/nar\/gks984","article-title":"The Papillomavirus Episteme: a central resource for papillomavirus sequence data and analysis","volume":"41","author":"Van Doorslaer","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2021.06.004_bib109","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1158\/0008-5472.CAN-07-2754","article-title":"Type-dependent integration frequency of human papillomavirus genomes in cervical lesions","volume":"68","author":"Vinokurova","year":"2008","journal-title":"Cancer Res."},{"key":"10.1016\/j.cell.2021.06.004_bib110","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/j.1365-2133.2006.07734.x","article-title":"Multiple huge cutaneous horns overlying verrucae vulgaris induced by human papillomavirus type 2: a case report","volume":"156","author":"Wang","year":"2007","journal-title":"Br. J. 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