{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T19:36:09Z","timestamp":1792870569167,"version":"4.5.0"},"reference-count":81,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T00:00:00Z","timestamp":1727481600000},"content-version":"vor","delay-in-days":393,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFA1100100"],"award-info":[{"award-number":["2021YFA1100100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2019YFA0110000"],"award-info":[{"award-number":["2019YFA0110000"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011186","name":"Institute of Zoology, Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011186","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32050214"],"award-info":[{"award-number":["32050214"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32090012"],"award-info":[{"award-number":["32090012"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32225017"],"award-info":[{"award-number":["32225017"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.cell.2023.08.020","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T10:40:45Z","timestamp":1694428845000},"page":"4271-4288.e24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":92,"title":["Spatiotemporal insight into early pregnancy governed by immune-featured stromal cells"],"prefix":"10.1016","volume":"186","author":[{"given":"Min","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennie","family":"Ong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanju","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feixiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Kitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tengfei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2023.08.020_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-019-13489-4","article-title":"Primary decidual zone formation requires Scribble for pregnancy success in mice","volume":"10","author":"Yuan","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2023.08.020_bib2","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aat6114","article-title":"Immune responses at the maternal-fetal interface","volume":"4","author":"Ander","year":"2019","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.cell.2023.08.020_bib3","series-title":"The Guide to Investigation of Mouse Pregnancy. 11-Decidualization and Endometrial Extracellular Matrix Remodeling","author":"Favaro","year":"2014"},{"key":"10.1016\/j.cell.2023.08.020_bib4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1055\/s-0029-1242989","article-title":"Endometrial decidualization: of mice and men","volume":"28","author":"Ramathal","year":"2010","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.cell.2023.08.020_bib5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/abbs\/gmz146","article-title":"Regulatory mechanisms of endometrial decidualization and pregnancy-related diseases","volume":"52","author":"Sang","year":"2020","journal-title":"Acta Biochim. Biophys. Sin. (Shanghai)"},{"key":"10.1016\/j.cell.2023.08.020_bib6","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1038\/nm.3012","article-title":"Mechanisms of implantation: strategies for successful pregnancy","volume":"18","author":"Cha","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.cell.2023.08.020_bib7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/s42003-020-0763-1","article-title":"Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window","volume":"3","author":"Lucas","year":"2020","journal-title":"Commun. Biol."},{"key":"10.1016\/j.cell.2023.08.020_bib8","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aau4788","article-title":"A single-cell survey of the human first-trimester placenta and decidua","volume":"4","author":"Suryawanshi","year":"2018","journal-title":"Sci. Adv."},{"key":"10.1016\/j.cell.2023.08.020_bib9","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/s41586-018-0698-6","article-title":"Single-cell reconstruction of the early maternal-fetal interface in humans","volume":"563","author":"Vento-Tormo","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.cell.2023.08.020_bib10","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1007\/s43032-019-00030-7","article-title":"Alternatively activated macrophages are the primary retinoic acid-producing cells in human decidua","volume":"27","author":"Rajakumar","year":"2020","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.cell.2023.08.020_bib11","doi-asserted-by":"crossref","DOI":"10.1095\/biolreprod.112.102830","article-title":"Imaging of vascular development in early mouse decidua and its association with leukocytes and trophoblasts","volume":"87","author":"Croy","year":"2012","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cell.2023.08.020_bib12","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s00281-016-0574-0","article-title":"The decidua-the maternal bed embracing the embryo-maintains the pregnancy","volume":"38","author":"Mori","year":"2016","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.cell.2023.08.020_bib13","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/j.1600-0897.2012.01165.x","article-title":"A cross-talk of decidual stromal cells, trophoblast, and immune cells: a prerequisite for the success of pregnancy","volume":"68","author":"Oreshkova","year":"2012","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.cell.2023.08.020_bib14","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/cmi.2014.63","article-title":"Leukocyte driven-decidual angiogenesis in early pregnancy","volume":"11","author":"Lima","year":"2014","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.cell.2023.08.020_bib15","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/s41576-021-00370-8","article-title":"Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics","volume":"22","author":"Longo","year":"2021","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.cell.2023.08.020_bib16","doi-asserted-by":"crossref","DOI":"10.1002\/bies.201900221","article-title":"Spatially resolved transcriptomes-next generation tools for tissue exploration","volume":"42","author":"Asp","year":"2020","journal-title":"BioEssays"},{"key":"10.1016\/j.cell.2023.08.020_bib17","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.cell.2022.04.003","article-title":"Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays","volume":"185","author":"Chen","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.cell.2023.08.020_bib19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/s41576-019-0169-4","article-title":"Mechanisms of early placental development in mouse and humans","volume":"21","author":"Hemberger","year":"2020","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.cell.2023.08.020_bib20","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1038\/s41586-019-0933-9","article-title":"A single-cell molecular map of mouse gastrulation and early organogenesis","volume":"566","author":"Pijuan-Sala","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.cell.2023.08.020_bib21","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2018.00080","article-title":"Mouse yolk sac hematopoiesis","volume":"6","author":"Yamane","year":"2018","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.cell.2023.08.020_bib18","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1600-0897.2007.00525.x","article-title":"Distribution and spatiotemporal relationship of activin a and follistatin in mouse decidual and placental tissue","volume":"58","author":"Candeloro","year":"2007","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.cell.2023.08.020_bib22","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1002\/emmm.201302618","article-title":"VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy","volume":"5","author":"Kim","year":"2013","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.cell.2023.08.020_bib23","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.devcel.2009.01.015","article-title":"Angiogenesis: a team effort coordinated by notch","volume":"16","author":"Phng","year":"2009","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cell.2023.08.020_bib24","doi-asserted-by":"crossref","DOI":"10.1186\/s13221-015-0034-y","article-title":"Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus","volume":"7","author":"Shawber","year":"2015","journal-title":"Vasc. Cell"},{"key":"10.1016\/j.cell.2023.08.020_bib25","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1215\/S1152851705000232","article-title":"The role of pericytes in blood-vessel formation and maintenance","volume":"7","author":"Bergers","year":"2005","journal-title":"Neuro. Oncol"},{"key":"10.1016\/j.cell.2023.08.020_bib26","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.mod.2019.02.002","article-title":"Hemodynamic force is required for vascular smooth muscle cell recruitment to blood vessels during mouse embryonic development","volume":"156","author":"Padget","year":"2019","journal-title":"Mech. Dev."},{"key":"10.1016\/j.cell.2023.08.020_bib27","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/756078","article-title":"Extracellular matrix modulates angiogenesis in physiological and pathological conditions","volume":"2014","author":"Neve","year":"2014","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.cell.2023.08.020_bib28","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1387\/ijdb.082761eb","article-title":"Trophoblast phagocytic program: roles in different placental systems","volume":"54","author":"Bevilacqua","year":"2010","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.cell.2023.08.020_bib29","doi-asserted-by":"crossref","first-page":"5310","DOI":"10.1210\/endo.140.11.7148","article-title":"Differential uterine expression of estrogen and progesterone receptors correlates with uterine preparation for implantation and decidualization in the mouse","volume":"140","author":"Tan","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.cell.2023.08.020_bib30","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21114092","article-title":"Endometrial decidualization: the primary driver of pregnancy health","volume":"21","author":"Ng","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cell.2023.08.020_bib31","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1530\/REP-11-0060","article-title":"Evidence for a conserved function of heart and neural crest derivatives expressed transcript 2 in mouse and human decidualization","volume":"142","author":"Huyen","year":"2011","journal-title":"Reproduction"},{"key":"10.1016\/j.cell.2023.08.020_bib32","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s004180000141","article-title":"Organization of desmin-containing intermediate filaments during differentiation of mouse decidual cells","volume":"113","author":"Oliveira","year":"2000","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.cell.2023.08.020_bib33","doi-asserted-by":"crossref","DOI":"10.3390\/nu13020490","article-title":"Creatine metabolism in female reproduction, pregnancy and newborn health","volume":"13","author":"Muccini","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.cell.2023.08.020_bib34","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1073\/pnas.98.3.1047","article-title":"Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors","volume":"98","author":"Paria","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2023.08.020_bib35","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1006\/dbio.1999.9206","article-title":"Zonula occludens-1 and E-cadherin are coordinately expressed in the mouse uterus with the initiation of implantation and decidualization","volume":"208","author":"Paria","year":"1999","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cell.2023.08.020_bib36","doi-asserted-by":"crossref","first-page":"D1136","DOI":"10.1093\/nar\/gkz849","article-title":"MatrisomeDB: the ECM-protein knowledge database","volume":"48","author":"Shao","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2023.08.020_bib37","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1038\/s41586-019-0969-x","article-title":"The single-cell transcriptional landscape of mammalian organogenesis","volume":"566","author":"Cao","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.cell.2023.08.020_bib38","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/nbt.2859","article-title":"The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells","volume":"32","author":"Trapnell","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.cell.2023.08.020_bib39","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1093\/humupd\/dmy035","article-title":"The role of mesenchymal-epithelial transition in endometrial function","volume":"25","author":"Owusu-Akyaw","year":"2019","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.cell.2023.08.020_bib40","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cels.2019.03.003","article-title":"DoubletFinder: doublet detection in single-cell RNA sequencing data using artificial nearest neighbors","volume":"8","author":"McGinnis","year":"2019","journal-title":"Cell Syst."},{"key":"10.1016\/j.cell.2023.08.020_bib41","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2015.00601","article-title":"Natural killer cell immunomodulation: targeting activating, inhibitory, and co-stimulatory receptor signaling for cancer immunotherapy","volume":"6","author":"Chester","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cell.2023.08.020_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2020.00519","article-title":"Mechanisms ensuring endothelial junction integrity beyond VE-cadherin","volume":"11","author":"Duong","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.cell.2023.08.020_bib43","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s00441-012-1337-4","article-title":"Angiopoietin-like gene expression in the mouse uterus during implantation and in response to steroids","volume":"348","author":"Scott","year":"2012","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.cell.2023.08.020_bib44","doi-asserted-by":"crossref","first-page":"10730","DOI":"10.1111\/jcmm.15696","article-title":"Decreased ANGPTL4 impairs endometrial angiogenesis during peri-implantation period in patients with recurrent implantation failure","volume":"24","author":"Li","year":"2020","journal-title":"J.\u00a0Cell. Mol. Med."},{"key":"10.1016\/j.cell.2023.08.020_bib45","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.3892\/mmr.2020.11185","article-title":"Angiopoietin-2 regulated by progesterone induces uterine vascular remodeling during pregnancy","volume":"22","author":"Park","year":"2020","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.cell.2023.08.020_bib46","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1095\/biolreprod.106.059089","article-title":"Calcitonin gene-related peptide (CALCA) is a proangiogenic growth factor in the human placental development","volume":"76","author":"Dong","year":"2007","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cell.2023.08.020_bib47","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s10456-021-09818-1","article-title":"Chemerin regulates normal angiogenesis and hypoxia-driven neovascularization","volume":"25","author":"Ben Dhaou","year":"2022","journal-title":"Angiogenesis"},{"key":"10.1016\/j.cell.2023.08.020_bib48","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1210\/jc.2012-1102","article-title":"Chemerin regulates NK cell accumulation and endothelial cell morphogenesis in the decidua during early pregnancy","volume":"97","author":"Carlino","year":"2012","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cell.2023.08.020_bib49","series-title":"Early Pregnancy Loss","article-title":"Genetic aspects of the CBA\u00a0\u00d7\u00a0DBA\/2 and B10\u00a0\u00d7\u00a0B10.A models of murine pregnancy failure and its prevention by lymphocyte immunisation","author":"Chaouat","year":"1988"},{"key":"10.1016\/j.cell.2023.08.020_bib50","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.13125","article-title":"Single-cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion","volume":"54","author":"Du","year":"2021","journal-title":"Cell Prolif."},{"key":"10.1016\/j.cell.2023.08.020_bib51","doi-asserted-by":"crossref","first-page":"3650","DOI":"10.1242\/dev.133462","article-title":"From the stem of the placental tree: trophoblast stem cells and their progeny","volume":"143","author":"Latos","year":"2016","journal-title":"Development"},{"key":"10.1016\/j.cell.2023.08.020_bib52","article-title":"Control of regional decidualization in implantation: role of FoxM1 downstream of Hoxa10 and cyclin D3","volume":"5","author":"Gao","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cell.2023.08.020_bib53","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0026774","article-title":"Decidual cell polyploidization necessitates mitochondrial activity","volume":"6","author":"Ma","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.cell.2023.08.020_bib54","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1095\/biolreprod.110.087239","article-title":"Nodal expression in the uterus of the mouse is regulated by the embryo and correlates with implantation","volume":"84","author":"Park","year":"2011","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cell.2023.08.020_bib55","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1600-065X.2006.00447.x","article-title":"Uterine natural killer cells: a specialized differentiation regulated by ovarian hormones","volume":"214","author":"Croy","year":"2006","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cell.2023.08.020_bib56","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/nri2990","article-title":"Fibrocytes: emerging effector cells in chronic inflammation","volume":"11","author":"Reilkoff","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cell.2023.08.020_bib57","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/s41576-019-0093-7","article-title":"Integrative single-cell analysis","volume":"20","author":"Stuart","year":"2019","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.cell.2023.08.020_bib58","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-18794-x","article-title":"Concepts of extracellular matrix remodelling in tumour progression and metastasis","volume":"11","author":"Winkler","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2023.08.020_bib59","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/s41568-019-0238-1","article-title":"A framework for advancing our understanding of cancer-associated fibroblasts","volume":"20","author":"Sahai","year":"2020","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.cell.2023.08.020_bib60","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1016\/j.cell.2019.05.031","article-title":"Comprehensive integration of single-cell data","volume":"177","author":"Stuart","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.cell.2023.08.020_bib61","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.cell.2023.08.020_bib62","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1038\/s41590-018-0276-y","article-title":"Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage","volume":"20","author":"Aran","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.cell.2023.08.020_bib63","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/nmeth.4150","article-title":"Single-cell mRNA quantification and differential analysis with Census","volume":"14","author":"Qiu","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2023.08.020_bib64","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1038\/nmeth.4402","article-title":"Reversed graph embedding resolves complex single-cell trajectories","volume":"14","author":"Qiu","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2023.08.020_bib65","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-21246-9","article-title":"Inference and analysis of cell-cell communication using CellChat","volume":"12","author":"Jin","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2023.08.020_bib66","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with Harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2023.08.020_bib67","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1038\/nmeth.4463","article-title":"SCENIC: single-cell regulatory network inference and clustering","volume":"14","author":"Aibar","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2023.08.020_bib68","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1038\/s41596-020-0336-2","article-title":"A scalable SCENIC workflow for single-cell gene regulatory network analysis","volume":"15","author":"Van de Sande","year":"2020","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.cell.2023.08.020_bib69","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: an R package for comparing biological themes among gene clusters","volume":"16","author":"Yu","year":"2012","journal-title":"Omics"},{"key":"10.1016\/j.cell.2023.08.020_bib70","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.cell.2023.08.020_bib71","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/s41587-019-0201-4","article-title":"Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype","volume":"37","author":"Kim","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.cell.2023.08.020_bib72","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"featureCounts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"30","author":"Liao","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.cell.2023.08.020_bib73","doi-asserted-by":"crossref","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.cell.2023.08.020_bib74","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nn.2467","article-title":"A robust and high-throughput Cre reporting and characterization system for the whole mouse brain","volume":"13","author":"Madisen","year":"2010","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cell.2023.08.020_bib75","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/nmeth.2563","article-title":"In situ sequencing for RNA analysis in preserved tissue and cells","volume":"10","author":"Ke","year":"2013","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2023.08.020_bib76","first-page":"116","article-title":"Imaging of individual transcripts by amplification-based single-molecule fluorescence in\u00a0situ hybridization","volume":"61","author":"Lin","year":"2021","journal-title":"N.\u00a0Biotechnol."},{"key":"10.1016\/j.cell.2023.08.020_bib77","doi-asserted-by":"crossref","DOI":"10.3791\/55168","article-title":"Isolation of mouse endometrial epithelial and stromal cells for in\u00a0vitro decidualization","author":"De Clercq","year":"2017","journal-title":"J.\u00a0Vis. Exp."},{"key":"10.1016\/j.cell.2023.08.020_bib78","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.cell.2020.01.015","article-title":"Single-cell transcriptome atlas of murine endothelial cells","volume":"180","author":"Kalucka","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.cell.2023.08.020_bib79","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1038\/s41591-018-0096-5","article-title":"Phenotype molding of stromal cells in the lung tumor microenvironment","volume":"24","author":"Lambrechts","year":"2018","journal-title":"Nat. Med."},{"key":"10.1016\/j.cell.2023.08.020_bib80","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1016\/j.cell.2021.04.020","article-title":"Mouse totipotent stem cells captured and maintained through spliceosomal repression","volume":"184","author":"Shen","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.cell.2023.08.020_bib81","series-title":"shiny: Web Application Framework for R","author":"Chang","year":"2023"}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867423009091?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867423009091?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:18:06Z","timestamp":1777475886000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867423009091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":81,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S0092867423009091"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2023.08.020","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spatiotemporal insight into early pregnancy governed by immune-featured stromal cells","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2023.08.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}