{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T21:00:50Z","timestamp":1786482050194,"version":"build-2736575974"},"reference-count":122,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"vor","delay-in-days":389,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000265","name":"UKRI Medical Research Council","doi-asserted-by":"publisher","award":["MR\/T029471\/1"],"award-info":[{"award-number":["MR\/T029471\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 GM1101149"],"award-info":[{"award-number":["R01 GM1101149"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P01 CA265794"],"award-info":[{"award-number":["P01 CA265794"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["CA174904"],"award-info":[{"award-number":["CA174904"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["221524\/Z\/20\/Z"],"award-info":[{"award-number":["221524\/Z\/20\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["220628\/Z\/20\/Z"],"award-info":[{"award-number":["220628\/Z\/20\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["222531\/Z\/21\/Z"],"award-info":[{"award-number":["222531\/Z\/21\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["208385\/Z\/17\/Z"],"award-info":[{"award-number":["208385\/Z\/17\/Z"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["223810\/Z\/21\/Z"],"award-info":[{"award-number":["223810\/Z\/21\/Z"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/L015056\/1"],"award-info":[{"award-number":["BB\/L015056\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["PR\/jw\/md\/22597"],"award-info":[{"award-number":["PR\/jw\/md\/22597"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000288","name":"Royal Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000288","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.cell.2024.03.002","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T10:37:01Z","timestamp":1711708621000},"page":"2250-2268.e31","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity"],"prefix":"10.1016","volume":"187","author":[{"given":"Vidhya","family":"Krishnamoorthy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Foglizzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Dilley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arindam","family":"Datta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parul","family":"Dutta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa J.","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oksana","family":"Degtjarik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura J.","family":"Musgrove","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio N.","family":"Calabrese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elton","family":"Zeqiraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1326-8981","authenticated-orcid":false,"given":"Roger A.","family":"Greenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2024.03.002_bib1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1146\/annurev-biochem-061516-044908","article-title":"Proteasomal and Autophagic Degradation Systems","volume":"86","author":"Dikic","year":"2017","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.cell.2024.03.002_bib2","doi-asserted-by":"crossref","first-page":"1253596","DOI":"10.1126\/science.1253596","article-title":"Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication","volume":"346","author":"Maric","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.cell.2024.03.002_bib3","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1126\/science.1253585","article-title":"Polyubiquitylation drives replisome disassembly at the termination of DNA replication","volume":"346","author":"Moreno","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.cell.2024.03.002_bib4","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/nature14887","article-title":"The mechanism of DNA replication termination in vertebrates","volume":"525","author":"Dewar","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.cell.2024.03.002_bib5","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1101\/gad.291799.116","article-title":"CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination","volume":"31","author":"Dewar","year":"2017","journal-title":"Genes Dev."},{"key":"10.1016\/j.cell.2024.03.002_bib6","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1038\/ncb3500","article-title":"CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis","volume":"19","author":"Sonneville","year":"2017","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib7","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202052164","article-title":"CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle","volume":"22","author":"Villa","year":"2021","journal-title":"EMBO Rep."},{"key":"10.1016\/j.cell.2024.03.002_bib8","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202009147","article-title":"LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components","volume":"220","author":"Fan","year":"2021","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib9","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1038\/s41467-020-14898-6","article-title":"Structure of the processive human Pol \u03b4 holoenzyme","volume":"11","author":"Lancey","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2024.03.002_bib10","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.molcel.2016.12.020","article-title":"Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork","volume":"65","author":"Choe","year":"2017","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib11","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/nature20099","article-title":"Break-induced telomere synthesis underlies alternative telomere maintenance","volume":"539","author":"Dilley","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.cell.2024.03.002_bib12","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.tig.2020.12.003","article-title":"Underappreciated Roles of DNA Polymerase \u03b4 in Replication Stress Survival","volume":"37","author":"Fuchs","year":"2021","journal-title":"Trends Genet."},{"key":"10.1016\/j.cell.2024.03.002_bib13","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s13023-016-0509-9","article-title":"SPATA5 mutations cause a distinct autosomal recessive phenotype of intellectual disability, hypotonia and hearing loss","volume":"11","author":"Buchert","year":"2016","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.cell.2024.03.002_bib14","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/cge.12813","article-title":"Characterization of SPATA5-related encephalopathy in early childhood","volume":"90","author":"Kurata","year":"2016","journal-title":"Clin. Genet."},{"key":"10.1016\/j.cell.2024.03.002_bib15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/5584_2016_206","article-title":"Isolated Hearing Impairment Caused by SPATA5 Mutations in a Family with Variable Phenotypic Expression","volume":"980","author":"Szcza\u0142uba","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib16","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.ajhg.2015.07.014","article-title":"Mutations in SPATA5 Are Associated with Microcephaly, Intellectual Disability, Seizures, and Hearing Loss","volume":"97","author":"Tanaka","year":"2015","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.cell.2024.03.002_bib17","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/s41431-017-0001-6","article-title":"Compound heterozygous SPATA5 variants in four families and functional studies of SPATA5 deficiency","volume":"26","author":"Puusepp","year":"2018","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.cell.2024.03.002_bib18","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1016\/j.ajhg.2021.08.003","article-title":"Bi-allelic variants in SPATA5L1 lead to intellectual disability, spastic-dystonic cerebral palsy, epilepsy, and hearing loss","volume":"108","author":"Richard","year":"2021","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.cell.2024.03.002_bib19","series-title":"DepMap 22Q2 Public","year":"2022"},{"key":"10.1016\/j.cell.2024.03.002_bib20","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/s41580-019-0183-6","article-title":"The molecular principles governing the activity and functional diversity of AAA+ proteins","volume":"21","author":"Puchades","year":"2020","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib21","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12875","article-title":"C1orf109L binding DHX9 promotes DNA damage depended on the R-loop accumulation and enhances camptothecin chemosensitivity","volume":"53","author":"Dou","year":"2020","journal-title":"Cell Prolif."},{"key":"10.1016\/j.cell.2024.03.002_bib22","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1423-0127-19-49","article-title":"Identification and characterization of a novel gene, c1orf109, encoding a CK2 substrate that is involved in cancer cell proliferation","volume":"19","author":"Liu","year":"2012","journal-title":"J.\u00a0Biomed. Sci."},{"key":"10.1016\/j.cell.2024.03.002_bib23","doi-asserted-by":"crossref","first-page":"19304","DOI":"10.1073\/pnas.0909345106","article-title":"Functional genomic screens identify CINP as a genome maintenance protein","volume":"106","author":"Lovejoy","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2024.03.002_bib24","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.molcel.2009.06.021","article-title":"A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability","volume":"35","author":"Paulsen","year":"2009","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib25","first-page":"1120","article-title":"A novel Cdk2 interactor is phosphorylated by Cdc7 and associates with components of the replication complexes","volume":"4","author":"Grishina","year":"2005","journal-title":"Cell Cycle Georget. Tex."},{"key":"10.1016\/j.cell.2024.03.002_bib26","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.molcel.2017.10.028","article-title":"VCP\/p97-Mediated Unfolding as a Principle in Protein Homeostasis and Signaling","volume":"69","author":"van den Boom","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib27","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.cell.2017.04.020","article-title":"Molecular Mechanism of Substrate Processing by the Cdc48 ATPase Complex","volume":"169","author":"Bodnar","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib28","doi-asserted-by":"crossref","first-page":"E4380","DOI":"10.1073\/pnas.1706205114","article-title":"Ubiquitin- and ATP-dependent unfoldase activity of P97\/VCP\u22c5NPLOC4\u22c5UFD1L is enhanced by a mutation that causes multisystem proteinopathy","volume":"114","author":"Blythe","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2024.03.002_bib29","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.12688\/f1000research.11683.1","article-title":"Toward an understanding of the Cdc48\/p97 ATPase","volume":"6","author":"Bodnar","year":"2017","journal-title":"F1000Res"},{"key":"10.1016\/j.cell.2024.03.002_bib30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nrm3270","article-title":"The unfolded protein response: controlling cell fate decisions under ER stress and beyond","volume":"13","author":"Hetz","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib31","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1126\/science.aad7974","article-title":"2.3\u00a0\u00c5 resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition","volume":"351","author":"Banerjee","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.cell.2024.03.002_bib32","doi-asserted-by":"crossref","first-page":"101187","DOI":"10.1016\/j.jbc.2021.101187","article-title":"AAA+ ATPase p97\/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation","volume":"297","author":"Caffrey","year":"2021","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.cell.2024.03.002_bib33","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","article-title":"Highly accurate protein structure prediction with AlphaFold","volume":"596","author":"Jumper","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.cell.2024.03.002_bib34","doi-asserted-by":"crossref","first-page":"D439","DOI":"10.1093\/nar\/gkab1061","article-title":"AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models","volume":"50","author":"Varadi","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2024.03.002_bib35","article-title":"Protein complex prediction with AlphaFold-Multimer","author":"Evans","year":"2021","journal-title":"bioRxiv"},{"key":"10.1016\/j.cell.2024.03.002_bib36","doi-asserted-by":"crossref","first-page":"10236","DOI":"10.1021\/acs.analchem.9b02372","article-title":"A Simple Cross-Linking\/Mass Spectrometry Workflow for Studying System-wide Protein Interactions","volume":"91","author":"G\u00f6tze","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.cell.2024.03.002_bib37","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.molcel.2006.03.036","article-title":"Central pore residues mediate the p97\/VCP activity required for ERAD","volume":"22","author":"DeLaBarre","year":"2006","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib38","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.febslet.2007.02.031","article-title":"Mutations in p97\/VCP induce unfolding activity","volume":"581","author":"Rothballer","year":"2007","journal-title":"FEBS Lett."},{"key":"10.1016\/j.cell.2024.03.002_bib39","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/pro.3743","article-title":"Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP-dependent substrate translocation","volume":"29","author":"Gates","year":"2020","journal-title":"Protein Sci."},{"key":"10.1016\/j.cell.2024.03.002_bib40","doi-asserted-by":"crossref","first-page":"31458","DOI":"10.1074\/jbc.M113.511337","article-title":"Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry","volume":"288","author":"Sirbu","year":"2013","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.cell.2024.03.002_bib41","doi-asserted-by":"crossref","first-page":"565268","DOI":"10.1155\/2010\/565268","article-title":"Diagnostic Overlap between Fanconi Anemia and the Cohesinopathies: Roberts Syndrome and Warsaw Breakage Syndrome","volume":"2010","author":"van der Lelij","year":"2010","journal-title":"Anemia"},{"key":"10.1016\/j.cell.2024.03.002_bib42","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.ajhg.2010.01.008","article-title":"Warsaw breakage syndrome, a cohesinopathy associated with mutations in the XPD helicase family member DDX11\/ChlR1","volume":"86","author":"van der Lelij","year":"2010","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.cell.2024.03.002_bib43","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.cell.2022.12.044","article-title":"A replication fork determinant for the establishment of sister chromatid cohesion","volume":"186","author":"Minamino","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib44","article-title":"Sister chromatid cohesion establishment during DNA replication termination","author":"Cameron","year":"2022","journal-title":"bioRxiv"},{"key":"10.1016\/j.cell.2024.03.002_bib45","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1093\/nar\/gky519","article-title":"Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing","volume":"47","author":"Carvajal-Maldonado","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2024.03.002_bib46","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.devcel.2020.01.024","article-title":"WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion","volume":"52","author":"Benedict","year":"2020","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib47","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.molcel.2017.10.012","article-title":"Cohesin Ubiquitylation and Mobilization Facilitate Stalled Replication Fork Dynamics","volume":"68","author":"Frattini","year":"2017","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib48","doi-asserted-by":"crossref","first-page":"101450","DOI":"10.1016\/j.jbc.2021.101450","article-title":"The small-molecule BMH-21 directly inhibits transcription elongation and DNA occupancy of RNA polymerase I in\u00a0vivo and in\u00a0vitro","volume":"298","author":"Jacobs","year":"2022","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.cell.2024.03.002_bib49","doi-asserted-by":"crossref","DOI":"10.1093\/narcan\/zcaa032","article-title":"The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability","volume":"2","author":"Mars","year":"2020","journal-title":"NAR Cancer"},{"key":"10.1016\/j.cell.2024.03.002_bib50","doi-asserted-by":"crossref","first-page":"110597","DOI":"10.1016\/j.celrep.2022.110597","article-title":"Labeling of heterochronic ribosomes reveals C1ORF109 and SPATA5 control a late step in human ribosome assembly","volume":"38","author":"Ni","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.cell.2024.03.002_bib51","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1093\/oxfordjournals.jbchem.a021280","article-title":"Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine","volume":"119","author":"Tsubuki","year":"1996","journal-title":"J.\u00a0Biochem."},{"key":"10.1016\/j.cell.2024.03.002_bib52","doi-asserted-by":"crossref","first-page":"4335","DOI":"10.1128\/MCB.06075-11","article-title":"Calpain-1 Cleaves Rad21 To Promote Sister Chromatid Separation","volume":"31","author":"Panigrahi","year":"2011","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib53","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1002\/pro.666","article-title":"The N-end rule pathway and regulation by proteolysis","volume":"20","author":"Varshavsky","year":"2011","journal-title":"Protein Sci."},{"key":"10.1016\/j.cell.2024.03.002_bib54","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1073\/pnas.1816596116","article-title":"N-degron and C-degron pathways of protein degradation","volume":"116","author":"Varshavsky","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2024.03.002_bib55","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/j.cell.2018.04.028","article-title":"The Eukaryotic Proteome Is Shaped by E3\u00a0Ubiquitin Ligases Targeting C-Terminal Degrons","volume":"173","author":"Koren","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib56","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.molcel.2018.04.006","article-title":"C-Terminal End-Directed Protein Elimination by CRL2\u00a0Ubiquitin Ligases","volume":"70","author":"Lin","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib57","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1080\/10409238.2021.1979460","article-title":"The AAA+\u2009superfamily: a review of the structural and mechanistic principles of these molecular machines","volume":"57","author":"Khan","year":"2022","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib58","doi-asserted-by":"crossref","first-page":"9294307","DOI":"10.1155\/2016\/9294307","article-title":"Fundamental Characteristics of AAA+ Protein Family Structure and Function","volume":"2016","author":"Miller","year":"2016","journal-title":"Archaea"},{"key":"10.1016\/j.cell.2024.03.002_bib59","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3389\/fmolb.2017.00039","article-title":"A Mighty \u201cProtein Extractor\u201d of the Cell: Structure and Function of the p97\/CDC48 ATPase","volume":"4","author":"Ye","year":"2017","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.cell.2024.03.002_bib60","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.molcel.2018.09.020","article-title":"Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation","volume":"72","author":"Weith","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib61","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.devcel.2006.10.016","article-title":"p37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis","volume":"11","author":"Uchiyama","year":"2006","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib62","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1038\/sj.emboj.7600152","article-title":"Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97","volume":"23","author":"Yuan","year":"2004","journal-title":"EMBO J."},{"key":"10.1016\/j.cell.2024.03.002_bib63","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1042\/BCJ20160783","article-title":"The AAA+ ATPase p97, a cellular multitool","volume":"474","author":"Stach","year":"2017","journal-title":"Biochem. J."},{"key":"10.1016\/j.cell.2024.03.002_bib64","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3389\/fmolb.2017.00021","article-title":"The Interplay of Cofactor Interactions and Post-translational Modifications in the Regulation of the AAA+ ATPase p97","volume":"4","author":"H\u00e4nzelmann","year":"2017","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.cell.2024.03.002_bib65","doi-asserted-by":"crossref","first-page":"eaax1033","DOI":"10.1126\/science.aax1033","article-title":"Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding","volume":"365","author":"Twomey","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.cell.2024.03.002_bib66","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.molcel.2021.11.033","article-title":"Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase","volume":"82","author":"Ji","year":"2022","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib67","doi-asserted-by":"crossref","first-page":"E4190","DOI":"10.1073\/pnas.1603980113","article-title":"Unfolding the mechanism of the AAA+ unfoldase VAT by a combined cryo-EM, solution NMR study","volume":"113","author":"Huang","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2024.03.002_bib68","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/nature14148","article-title":"Mechanistic insights into the recycling machine of the SNARE complex","volume":"518","author":"Zhao","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.cell.2024.03.002_bib69","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.cell.2008.09.055","article-title":"Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation","volume":"135","author":"Duncan","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib70","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/s41572-019-0113-0","article-title":"Chromosome instability syndromes","volume":"5","author":"Taylor","year":"2019","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.cell.2024.03.002_bib71","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1083\/jcb.201205021","article-title":"Rlp24 activates the AAA-ATPase Drg1 to initiate cytoplasmic pre-60S maturation","volume":"199","author":"Kappel","year":"2012","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib72","doi-asserted-by":"crossref","first-page":"6581","DOI":"10.1128\/MCB.00668-07","article-title":"Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1","volume":"27","author":"Pertschy","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib73","doi-asserted-by":"crossref","first-page":"E715","DOI":"10.3390\/biom9110715","article-title":"Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis","volume":"9","author":"Prattes","year":"2019","journal-title":"Biomolecules"},{"key":"10.1016\/j.cell.2024.03.002_bib74","doi-asserted-by":"crossref","first-page":"8597","DOI":"10.1038\/sj.onc.1207845","article-title":"Inactivation of the RRB1-Pescadillo pathway involved in ribosome biogenesis induces chromosomal instability","volume":"23","author":"Killian","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.cell.2024.03.002_bib75","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.tibs.2009.05.004","article-title":"When DNA replication and protein synthesis come together","volume":"34","author":"Berthon","year":"2009","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.cell.2024.03.002_bib76","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0092-8674(02)00773-0","article-title":"Yph1p, an ORC-interacting protein: potential links between cell proliferation control, DNA replication, and ribosome biogenesis","volume":"109","author":"Du","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib77","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1093\/emboj\/19.10.2181","article-title":"A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways","volume":"19","author":"Meyer","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.cell.2024.03.002_bib78","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1016\/S1097-2765(00)00143-X","article-title":"Structure of the AAA ATPase p97","volume":"6","author":"Zhang","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib79","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/nmeth.4347","article-title":"Addressing preferred specimen orientation in single-particle cryo-EM through tilting","volume":"14","author":"Tan","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2024.03.002_bib80","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1107\/S0907444909007835","article-title":"ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments","volume":"65","author":"Bond","year":"2009","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.cell.2024.03.002_bib81","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/s41592-022-01488-1","article-title":"ColabFold: making protein folding accessible to all","volume":"19","author":"Mirdita","year":"2022","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2024.03.002_bib82","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1107\/S0907444911007773","article-title":"Data processing and analysis with the autoPROC toolbox","volume":"67","author":"Vonrhein","year":"2011","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.cell.2024.03.002_bib83","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2024.03.002_bib84","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1186\/s12859-021-04344-9","article-title":"CellProfiler 4: improvements in speed, utility and usability","volume":"22","author":"Stirling","year":"2021","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.cell.2024.03.002_bib85","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1107\/S0907444910007493","article-title":"Features and development of Coot","volume":"66","author":"Emsley","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.cell.2024.03.002_bib86","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/nmeth.4169","article-title":"cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination","volume":"14","author":"Punjani","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2024.03.002_bib87","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jsb.2015.08.008","article-title":"CTFFIND4: Fast and accurate defocus estimation from electron micrographs","volume":"192","author":"Rohou","year":"2015","journal-title":"J.\u00a0Struct. Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib88","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2024.03.002_bib89","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1093\/molbev\/msy096","article-title":"MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms","volume":"35","author":"Kumar","year":"2018","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.cell.2024.03.002_bib90","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1093\/molbev\/msz312","article-title":"Molecular Evolutionary Genetics Analysis (MEGA) for macOS","volume":"37","author":"Stecher","year":"2020","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.cell.2024.03.002_bib91","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s13361-014-1001-1","article-title":"Automated assignment of MS\/MS cleavable cross-links in protein 3D-structure analysis","volume":"26","author":"G\u00f6tze","year":"2015","journal-title":"J.\u00a0Am. Soc. Mass Spectrom."},{"key":"10.1016\/j.cell.2024.03.002_bib92","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/pro.3330","article-title":"MolProbity: More and better reference data for improved all-atom structure validation","volume":"27","author":"Williams","year":"2018","journal-title":"Protein Sci."},{"key":"10.1016\/j.cell.2024.03.002_bib93","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/nmeth.4193","article-title":"MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy","volume":"14","author":"Zheng","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2024.03.002_bib94","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1093\/nar\/gkh340","article-title":"MUSCLE: multiple sequence alignment with high accuracy and high throughput","volume":"32","author":"Edgar","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2024.03.002_bib95","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/1471-2105-5-113","article-title":"MUSCLE: a multiple sequence alignment method with reduced time and space complexity","volume":"5","author":"Edgar","year":"2004","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.cell.2024.03.002_bib96","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1107\/S0021889807021206","article-title":"Phaser crystallographic software","volume":"40","author":"McCoy","year":"2007","journal-title":"J.\u00a0Appl. Crystallogr."},{"key":"10.1016\/j.cell.2024.03.002_bib97","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1107\/S0907444909052925","article-title":"PHENIX: a comprehensive Python-based system for macromolecular structure solution","volume":"66","author":"Adams","year":"2010","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.cell.2024.03.002_bib98","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1107\/S2059798319011471","article-title":"Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix","volume":"75","author":"Liebschner","year":"2019","journal-title":"Acta Crystallogr. D Struct. Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib99","doi-asserted-by":"crossref","first-page":"4169","DOI":"10.1042\/BCJ20210708","article-title":"New tools for automated cryo-EM single-particle analysis in RELION-4.0.","volume":"478","author":"Kimanius","year":"2021","journal-title":"Biochem. J."},{"key":"10.1016\/j.cell.2024.03.002_bib100","series-title":"STARANISO","author":"Tickle","year":"2018"},{"key":"10.1016\/j.cell.2024.03.002_bib101","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1107\/S0907444904026460","article-title":"Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions","volume":"60","author":"Krissinel","year":"2004","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.cell.2024.03.002_bib102","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/pro.3235","article-title":"UCSF ChimeraX: Meeting modern challenges in visualization and analysis","volume":"27","author":"Goddard","year":"2018","journal-title":"Protein Sci."},{"key":"10.1016\/j.cell.2024.03.002_bib103","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1002\/pro.3943","article-title":"UCSF ChimeraX: Structure visualization for researchers, educators, and developers","volume":"30","author":"Pettersen","year":"2021","journal-title":"Protein Sci."},{"key":"10.1016\/j.cell.2024.03.002_bib104","doi-asserted-by":"crossref","first-page":"4370","DOI":"10.1021\/acs.analchem.5b00140","article-title":"Bayesian deconvolution of mass and ion mobility spectra: from binary interactions to polydisperse ensembles","volume":"87","author":"Marty","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.cell.2024.03.002_bib105","article-title":"xiView: A common platform for the downstream analysis of Crosslinking Mass Spectrometry data","author":"Graham","year":"2019","journal-title":"bioRxiv"},{"key":"10.1016\/j.cell.2024.03.002_bib106","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nbt.3235","article-title":"Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains","volume":"33","author":"Shi","year":"2015","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.cell.2024.03.002_bib107","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1038\/ncb1865","article-title":"RAD18 transmits DNA damage signalling to elicit homologous recombination repair","volume":"11","author":"Huang","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib108","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/S0076-6879(03)70037-8","article-title":"Immunoaffinity purification of mammalian protein complexes","volume":"370","author":"Nakatani","year":"2003","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.cell.2024.03.002_bib109","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.molcel.2018.06.004","article-title":"The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication","volume":"71","author":"Hanzlikova","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib110","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.30473","article-title":"Rapid DNA replication origin licensing protects stem cell pluripotency","volume":"6","author":"Matson","year":"2017","journal-title":"eLife"},{"key":"10.1016\/j.cell.2024.03.002_bib111","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.molcel.2017.11.035","article-title":"Removal of RTF2 from stalled replisomes promotes maintenance of genome integrity","volume":"69","author":"Kottemann","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib112","doi-asserted-by":"crossref","first-page":"599","DOI":"10.15252\/embr.201439696","article-title":"The unfolded protein response is shaped by the NMD pathway","volume":"16","author":"Karam","year":"2015","journal-title":"EMBO Rep."},{"key":"10.1016\/j.cell.2024.03.002_bib113","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/B978-0-12-385114-7.00004-0","article-title":"Measuring ER stress and the unfolded protein response using mammalian tissue culture system","volume":"490","author":"Oslowski","year":"2011","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.cell.2024.03.002_bib114","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/s12862-016-0790-1","article-title":"Shedding light on the expansion and diversification of the Cdc48 protein family during the rise of the eukaryotic cell","volume":"16","author":"Kienle","year":"2016","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.cell.2024.03.002_bib115","doi-asserted-by":"crossref","first-page":"3710","DOI":"10.1093\/gbe\/evz265","article-title":"Emergence and Evolution of ERM Proteins and Merlin in Metazoans","volume":"12","author":"Shabardina","year":"2020","journal-title":"Genome Biol. Evol."},{"key":"10.1016\/j.cell.2024.03.002_bib116","doi-asserted-by":"crossref","first-page":"W276","DOI":"10.1093\/nar\/gkac240","article-title":"Search and sequence analysis tools services from EMBL-EBI in 2022","volume":"50","author":"Madeira","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2024.03.002_bib117","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/nmeth983","article-title":"Protein complex expression by using multigene baculoviral vectors","volume":"3","author":"Fitzgerald","year":"2006","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2024.03.002_bib118","doi-asserted-by":"crossref","first-page":"15815","DOI":"10.1073\/pnas.0507705102","article-title":"Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase","volume":"102","author":"Yin","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2024.03.002_bib119","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.molcel.2015.07.028","article-title":"Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function","volume":"59","author":"Zeqiraj","year":"2015","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib120","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/s41596-018-0084-8","article-title":"Collection, pre-processing and on-the-fly analysis of data for high-resolution, single-particle cryo-electron microscopy","volume":"14","author":"Thompson","year":"2019","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.cell.2024.03.002_bib121","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.molcel.2016.11.005","article-title":"Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway","volume":"65","author":"van Twest","year":"2017","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cell.2024.03.002_bib122","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1038\/s41467-020-15642-w","article-title":"Quantifying the heterogeneity of macromolecular machines by mass photometry","volume":"11","author":"Sonn-Segev","year":"2020","journal-title":"Nat. Commun."}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867424002502?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867424002502?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T04:50:56Z","timestamp":1762231856000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867424002502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":122,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S0092867424002502"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2024.03.002","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2024.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}