{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T18:47:07Z","timestamp":1792522027159,"version":"4.5.0"},"reference-count":77,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"vor","delay-in-days":134,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002426","name":"Fondazione Telethon","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002426","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["Wa 3783\/1"],"award-info":[{"award-number":["Wa 3783\/1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004410","name":"European Molecular Biology Organization","doi-asserted-by":"publisher","award":["ALTF 136-2017"],"award-info":[{"award-number":["ALTF 136-2017"]}],"id":[{"id":"10.13039\/100004410","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001708","name":"International Foundation for Research in Paraplegia","doi-asserted-by":"publisher","award":["IRP P 185F"],"award-info":[{"award-number":["IRP P 185F"]}],"id":[{"id":"10.13039\/501100001708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007606","name":"Soci\u00e9t\u00e9 Acad\u00e9mique de Gen\u00e8ve","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002803","name":"Fondazione Cariplo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002803","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006389","name":"Universit\u00e9 de Gen\u00e8ve","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006389","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031252","name":"Carigest","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031252","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006282","name":"Koning Boudewijnstichting","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006282","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008236","name":"Fondation Roger de Spoelberch","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008236","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.cell.2025.04.003","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T10:34:50Z","timestamp":1745836490000},"page":"3567-3582.e20","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Regional differences in progenitor metabolism shape brain growth during development"],"prefix":"10.1016","volume":"188","author":[{"given":"Natalia","family":"Baumann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin J.","family":"Wagener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awais","family":"Javed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Conti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Sansevrino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien","family":"Lavalley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elia","family":"Magrinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timea","family":"Szalai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Fuciec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clothilde","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Fi\u00e8vre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreane","family":"Fouassier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"D\u2019Amico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Harschnitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2438-4769","authenticated-orcid":false,"given":"Denis","family":"Jabaudon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2025.04.003_bib1","series-title":"Comparative Vertebrate Neuroanatomy","first-page":"73","article-title":"Vertebrate Phylogeny and Diversity in Brain Organization","author":"Butler","year":"2005"},{"key":"10.1016\/j.cell.2025.04.003_bib2","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.neuroimage.2015.04.044","article-title":"Morphology and morphometry of the human embryonic brain: A three-dimensional analysis","volume":"115","author":"Shiraishi","year":"2015","journal-title":"NeuroImage"},{"key":"10.1016\/j.cell.2025.04.003_bib3","first-page":"43","article-title":"Relative weight and volume of the component parts of the brain of the human embryo at different stages of development","volume":"13","author":"Jenkins","year":"1921","journal-title":"Contr. Embryol. Carneg. Instn."},{"key":"10.1016\/j.cell.2025.04.003_bib4","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1242\/dev.090571","article-title":"Neural progenitors, neurogenesis and the evolution of the neocortex","volume":"141","author":"Florio","year":"2014","journal-title":"Development"},{"key":"10.1016\/j.cell.2025.04.003_bib5","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1146\/annurev-neuro-062111-150543","article-title":"The role of organizers in patterning the nervous system","volume":"35","author":"Kiecker","year":"2012","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib6","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/j.devcel.2024.05.027","article-title":"Metabolic mechanisms of species-specific developmental tempo","volume":"59","author":"Iwata","year":"2024","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cell.2025.04.003_bib7","doi-asserted-by":"crossref","DOI":"10.1126\/science.abn4705","article-title":"Mitochondria metabolism sets the species-specific tempo of neuronal development","volume":"379","author":"Iwata","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.cell.2025.04.003_bib8","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1038\/s41593-022-01093-7","article-title":"Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex","volume":"25","author":"Dong","year":"2022","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib9","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.neuron.2020.11.014","article-title":"Metabolic Regulation of Neocortical Expansion in Development and Evolution","volume":"109","author":"Namba","year":"2021","journal-title":"Neuron"},{"key":"10.1016\/j.cell.2025.04.003_bib10","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.stem.2016.04.015","article-title":"Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program","volume":"19","author":"Khacho","year":"2016","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.cell.2025.04.003_bib11","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1126\/science.aba9760","article-title":"Mitochondrial dynamics in postmitotic cells regulate neurogenesis","volume":"369","author":"Iwata","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.cell.2025.04.003_bib12","doi-asserted-by":"crossref","first-page":"19797","DOI":"10.1074\/jbc.RA118.002742","article-title":"FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity","volume":"293","author":"Yien","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cell.2025.04.003_bib13","doi-asserted-by":"crossref","DOI":"10.3791\/2166","article-title":"Immunofluorescent Detection of Two Thymidine Analogues (CldU and IdU) in Primary Tissue","author":"Tuttle","year":"2010","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.cell.2025.04.003_bib14","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1038\/s41596-018-0038-1","article-title":"In vivo pulse labeling of isochronic cohorts of cells in the central nervous system using FlashTag","volume":"13","author":"Govindan","year":"2018","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.cell.2025.04.003_bib15","doi-asserted-by":"crossref","first-page":"6183","DOI":"10.1523\/JNEUROSCI.16-19-06183.1996","article-title":"The Leaving or Q Fraction of the Murine Cerebral Proliferative Epithelium: A General Model of Neocortical Neuronogenesis","volume":"16","author":"Takahashi","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib16","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1126\/science.aad8361","article-title":"Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex","volume":"351","author":"Telley","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.cell.2025.04.003_bib17","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/s41586-021-03775-x","article-title":"Molecular architecture of the developing mouse brain","volume":"596","author":"La Manno","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.cell.2025.04.003_bib18","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-09740-6","article-title":"Heterogeneous fates of simultaneously-born neurons in the cortical ventricular zone","volume":"12","author":"Magrinelli","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cell.2025.04.003_bib19","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s12264-022-00938-2","article-title":"Immunological Markers for Central Nervous System Glia","volume":"39","author":"Huang","year":"2023","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.cell.2025.04.003_bib20","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1007\/s12311-015-0724-2","article-title":"Consensus Paper: Cerebellar Development","volume":"15","author":"Leto","year":"2016","journal-title":"Cerebellum"},{"key":"10.1016\/j.cell.2025.04.003_bib21","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/192766b0","article-title":"Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse","volume":"192","author":"Angevine","year":"1961","journal-title":"Nature"},{"key":"10.1016\/j.cell.2025.04.003_bib22","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.celrep.2016.05.072","article-title":"Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity","volume":"16","author":"Mihalas","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.cell.2025.04.003_bib23","article-title":"Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types in cerebral cortex","author":"Huilgol","year":"2023","journal-title":"bioRxiv"},{"key":"10.1016\/j.cell.2025.04.003_bib24","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.conb.2010.10.002","article-title":"Cortical progenitor expansion, self-renewal and neurogenesis-a polarized perspective","volume":"21","author":"Fietz","year":"2011","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.cell.2025.04.003_bib25","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.tins.2013.06.004","article-title":"A developmental ontology for the mammalian brain based on the prosomeric model","volume":"36","author":"Puelles","year":"2013","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib26","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.1002\/1873-3468.12829","article-title":"Radial glia in the ventral telencephalon","volume":"591","author":"Turrero Garc\u00eda","year":"2017","journal-title":"FEBS Lett."},{"key":"10.1016\/j.cell.2025.04.003_bib27","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.neuron.2018.06.021","article-title":"Radial Glial Lineage Progression and Differential Intermediate Progenitor Amplification Underlie Striatal Compartments and Circuit Organization","volume":"99","author":"Kelly","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.cell.2025.04.003_bib28","doi-asserted-by":"crossref","DOI":"10.1186\/1749-8104-6-35","article-title":"Basal progenitor cells in the embryonic mouse thalamus - their molecular characterization and the role of neurogenins and Pax6","volume":"6","author":"Wang","year":"2011","journal-title":"Neural Dev."},{"key":"10.1016\/j.cell.2025.04.003_bib29","doi-asserted-by":"crossref","first-page":"3104","DOI":"10.1523\/JNEUROSCI.4444-03.2004","article-title":"Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene","volume":"24","author":"Li","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib30","doi-asserted-by":"crossref","DOI":"10.1126\/science.aav2522","article-title":"Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex","volume":"364","author":"Telley","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.cell.2025.04.003_bib31","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms1155","article-title":"Neural stem and progenitor cells shorten S-phase on commitment to neuron production","volume":"2","author":"Arai","year":"2011","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2025.04.003_bib32","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/nmeth.4074","article-title":"mScarlet: a bright monomeric red fluorescent protein for cellular imaging","volume":"14","author":"Bindels","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2025.04.003_bib33","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.neuron.2014.05.033","article-title":"A high resolution spatiotemporal atlas of gene expression of the developing mouse brain","volume":"83","author":"Thompson","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.cell.2025.04.003_bib34","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.cell.2022.04.003","article-title":"Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays","volume":"185","author":"Chen","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.cell.2025.04.003_bib35","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.cell.2018.06.036","article-title":"Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex","volume":"174","author":"Vitali","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.cell.2025.04.003_bib36","doi-asserted-by":"crossref","first-page":"7627","DOI":"10.1523\/JNEUROSCI.22-17-07627.2002","article-title":"Distinct Actions of Emx1, Emx2, andPax6 in Regulating the Specification of Areas in the Developing Neocortex","volume":"22","author":"Bishop","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib37","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.ydbio.2011.02.003","article-title":"Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning","volume":"352","author":"Wong","year":"2011","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cell.2025.04.003_bib38","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ydbio.2012.10.022","article-title":"Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability","volume":"373","author":"Di Giovannantonio","year":"2013","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cell.2025.04.003_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/cells9061489","article-title":"Development and Differentiation of Midbrain Dopaminergic Neuron: From Bench to Bedside","volume":"9","author":"Wang","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.cell.2025.04.003_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fnana.2013.00007","article-title":"Transcription factors define the neuroanatomical organization of the medullary reticular formation","volume":"7","author":"Gray","year":"2013","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.cell.2025.04.003_bib41","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nrm3591","article-title":"Molecular regulation of stem cell quiescence","volume":"14","author":"Cheung","year":"2013","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.cell.2025.04.003_bib42","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1080\/00207454.2020.1733563","article-title":"Silencing of PRDM5 increases cell proliferation and inhibits cell apoptosis in glioma","volume":"131","author":"Wang","year":"2021","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib43","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/15384101.2015.1124701","article-title":"The PCL1-p53 axis promotes cellular quiescence","volume":"15","author":"Brien","year":"2016","journal-title":"Cell Cycle"},{"key":"10.1016\/j.cell.2025.04.003_bib44","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/s41586-023-06984-8","article-title":"An epigenetic barrier sets the timing of human neuronal maturation","volume":"626","author":"Ciceri","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.cell.2025.04.003_bib45","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20231725","article-title":"SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency","volume":"221","author":"Chan","year":"2024","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cell.2025.04.003_bib46","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.mito.2012.10.008","article-title":"Knockdown of NYGGF4 (PID1) rescues insulin resistance and mitochondrial dysfunction induced by FCCP in 3T3-L1 adipocytes","volume":"12","author":"Shi","year":"2012","journal-title":"Mitochondrion"},{"key":"10.1016\/j.cell.2025.04.003_bib47","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1002\/stem.2605","article-title":"UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex","volume":"35","author":"Ji","year":"2017","journal-title":"Stem Cells"},{"key":"10.1016\/j.cell.2025.04.003_bib48","doi-asserted-by":"crossref","first-page":"D1541","DOI":"10.1093\/nar\/gkaa1011","article-title":"MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations","volume":"49","author":"Rath","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2025.04.003_bib49","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2017.273","article-title":"Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming","volume":"8","author":"Sun","year":"2017","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.cell.2025.04.003_bib50","doi-asserted-by":"crossref","DOI":"10.1128\/mcb.00143-22","article-title":"Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis","volume":"42","author":"Suzuki","year":"2022","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.cell.2025.04.003_bib51","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ydbio.2019.11.008","article-title":"A single-cell transcriptome atlas for zebrafish development","volume":"459","author":"Farnsworth","year":"2020","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cell.2025.04.003_bib52","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1010739","article-title":"A method to estimate the cellular composition of the mouse brain from heterogeneous datasets","volume":"18","author":"Rodarie","year":"2022","journal-title":"PLoS Comp. Biol."},{"key":"10.1016\/j.cell.2025.04.003_bib53","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-53254-w","article-title":"Developmental mouse brain common coordinate framework","volume":"15","author":"Kronman","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2025.04.003_bib54","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nrn.2018.19","article-title":"Lactate in the brain: from metabolic end-product to signalling molecule","volume":"19","author":"Magistretti","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib55","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1126\/science.1160809","article-title":"Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation","volume":"324","author":"Vander Heiden","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.cell.2025.04.003_bib56","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/s41586-021-04237-0","article-title":"Single-cell delineation of lineage and genetic identity in the mouse brain","volume":"601","author":"Bandler","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.cell.2025.04.003_bib57","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms11349","article-title":"Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells","volume":"7","author":"Okamoto","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2025.04.003_bib58","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.tibs.2015.12.001","article-title":"The Warburg Effect: How Does it Benefit Cancer Cells?","volume":"41","author":"Liberti","year":"2016","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.cell.2025.04.003_bib59","first-page":"384","article-title":"Mitochondrial diseases: expanding the diagnosis in the era of genetic testing","volume":"4","author":"Saneto","year":"2020","journal-title":"J. Transl. Genet. Genom."},{"key":"10.1016\/j.cell.2025.04.003_bib60","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1056\/NEJMoa064436","article-title":"A Lethal Defect of Mitochondrial and Peroxisomal Fission","volume":"356","author":"Waterham","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cell.2025.04.003_bib61","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.cell.2012.09.004","article-title":"Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition","volume":"151","author":"Sharpley","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.cell.2025.04.003_bib62","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1523\/JNEUROSCI.4974-14.2016","article-title":"Female-Specific Intergenerational Transmission Patterns of the Human Corticolimbic Circuitry","volume":"36","author":"Yamagata","year":"2016","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib63","doi-asserted-by":"crossref","DOI":"10.1242\/dev.199399","article-title":"Initiation of Otx2 expression in the developing mouse retina requires a unique enhancer and either Ascl1 or Neurog2 activity","volume":"148","author":"Kaufman","year":"2021","journal-title":"Development"},{"key":"10.1016\/j.cell.2025.04.003_bib64","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0038174","article-title":"miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons","volume":"7","author":"Pathania","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cell.2025.04.003_bib65","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1523\/JNEUROSCI.3648-05.2006","article-title":"Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus","volume":"26","author":"Zhao","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cell.2025.04.003_bib66","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1126\/science.1207385","article-title":"ER tubules mark sites of mitochondrial division","volume":"334","author":"Friedman","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.cell.2025.04.003_bib67","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1073\/pnas.0610155104","article-title":"Controlled expression of transgenes introduced by in vivo electroporation","volume":"104","author":"Matsuda","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2025.04.003_bib68","doi-asserted-by":"crossref","first-page":"30710","DOI":"10.1073\/pnas.2000942117","article-title":"mGreenLantern: a bright monomeric fluorescent protein with rapid expression and cell filling properties for neuronal imaging","volume":"117","author":"Campbell","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cell.2025.04.003_bib69","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/nbt.3437","article-title":"Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9","volume":"34","author":"Doench","year":"2016","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.cell.2025.04.003_bib70","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.cell.2013.12.001","article-title":"Dynamic imaging of genomic loci in living human cells by an optimized CRISPR\/Cas system","volume":"155","author":"Chen","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.cell.2025.04.003_bib71","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0051679","article-title":"Most Anti-BrdU Antibodies React with 2\u2032-Deoxy-5-Ethynyluridine \u2014 The Method for the Effective Suppression of This Cross-Reactivity","volume":"7","author":"Liboska","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cell.2025.04.003_bib72","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/nbt.1529","article-title":"Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling","volume":"27","author":"Chambers","year":"2009","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.cell.2025.04.003_bib73","doi-asserted-by":"crossref","DOI":"10.1242\/dev.200436","article-title":"Ikaros family proteins redundantly regulate temporal patterning in the developing mouse retina","volume":"150","author":"Javed","year":"2023","journal-title":"Development"},{"key":"10.1016\/j.cell.2025.04.003_bib74","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s10735-018-9761-8","article-title":"BrdU\/EdU dual labeling to determine the cell-cycle dynamics of defined cellular subpopulations","volume":"49","author":"Harris","year":"2018","journal-title":"J. Mol. Histol."},{"key":"10.1016\/j.cell.2025.04.003_bib75","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.mito.2021.06.005","article-title":"A hitchhiker\u2019s guide to mitochondrial quantification","volume":"59","author":"Hemel","year":"2021","journal-title":"Mitochondrion"},{"key":"10.1016\/j.cell.2025.04.003_bib76","doi-asserted-by":"crossref","first-page":"E87","DOI":"10.1152\/ajpendo.00457.2019","article-title":"A pipeline for multidimensional confocal analysis of mitochondrial morphology, function, and dynamics in pancreatic \u03b2-cells","volume":"318","author":"Chaudhry","year":"2020","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.cell.2025.04.003_bib77","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1016\/j.cell.2019.05.031","article-title":"Comprehensive Integration of Single-Cell Data","volume":"177","author":"Stuart","year":"2019","journal-title":"Cell"}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867425004052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867425004052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T12:28:40Z","timestamp":1779452920000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867425004052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":77,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0092867425004052"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2025.04.003","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regional differences in progenitor metabolism shape brain growth during development","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2025.04.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}