{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T21:57:24Z","timestamp":1792706244272,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,6,25]],"date-time":"2027-06-25T00:00:00Z","timestamp":1813881600000},"content-version":"am","delay-in-days":389,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.cell.2026.06.002","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T14:39:52Z","timestamp":1782398392000},"page":"3871-3882.e12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy"],"prefix":"10.1016","volume":"189","author":[{"given":"Daniel J.","family":"Baker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon M.","family":"Frommer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugur","family":"Uslu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kisha K.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils W.","family":"Engel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"George","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wencao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel I.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Roselle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp C.","family":"Rommel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina M.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sikander","family":"Hayat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoltan","family":"Arany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0241-3557","authenticated-orcid":false,"given":"Carl H.","family":"June","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cell.2026.06.002_bib1","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S0140-6736(25)00039-X","article-title":"Assessing the oncogenic risk: the long-term safety of autologous chimeric antigen receptor T cells","volume":"405","author":"Baker","year":"2025","journal-title":"Lancet"},{"key":"10.1016\/j.cell.2026.06.002_bib2","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/s41573-023-00807-1","article-title":"Mechanisms of resistance to chimeric antigen receptor-T cells in haematological malignancies","volume":"22","author":"Ruella","year":"2023","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.cell.2026.06.002_bib3","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/s41586-023-06243-w","article-title":"CAR T therapy beyond cancer: the evolution of a living drug","volume":"619","author":"Baker","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.cell.2026.06.002_bib4","doi-asserted-by":"crossref","DOI":"10.1001\/jama.2024.19462","article-title":"CAR T Cells and T-Cell Therapies for Cancer","volume":"332","author":"Brudno","year":"2024","journal-title":"JAMA"},{"key":"10.1016\/j.cell.2026.06.002_bib5","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1056\/NEJMoa2308917","article-title":"CD19 CAR T-Cell Therapy in Autoimmune Disease \u2014 A Case Series with Follow-up","volume":"390","author":"M\u00fcller","year":"2024","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cell.2026.06.002_bib6","doi-asserted-by":"crossref","first-page":"4471","DOI":"10.1016\/j.cell.2022.10.026","article-title":"CAR T therapy extends its reach to autoimmune diseases","volume":"185","author":"Baker","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.cell.2026.06.002_bib7","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/PPO.0000000000000257","article-title":"Antigen Discovery and Therapeutic Targeting in Hematologic Malignancies","volume":"23","author":"Braun","year":"2017","journal-title":"Cancer J."},{"key":"10.1016\/j.cell.2026.06.002_bib8","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/s41571-022-00704-3","article-title":"Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours","volume":"20","author":"Flugel","year":"2022","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.cell.2026.06.002_bib9","doi-asserted-by":"crossref","first-page":"6125","DOI":"10.1016\/j.cell.2024.09.022","article-title":"Empowering biomedical discovery with AI agents","volume":"187","author":"Gao","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.cell.2026.06.002_bib10","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/s41586-025-08710-y","article-title":"Towards multimodal foundation models in molecular cell biology","volume":"640","author":"Cui","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.cell.2026.06.002_bib11","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.neuron.2024.01.016","article-title":"Data science opportunities of large language models for neuroscience and biomedicine","volume":"112","author":"Bzdok","year":"2024","journal-title":"Neuron"},{"key":"10.1016\/j.cell.2026.06.002_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-45221-2","article-title":"CAR-T cell therapy targeting surface expression of TYRP1 to treat cutaneous and rare melanoma subtypes","volume":"15","author":"Jilani","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2026.06.002_bib13","article-title":"TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models","volume":"32","author":"Hackett","year":"2024","journal-title":"Mol. Ther.: Oncol."},{"key":"10.1016\/j.cell.2026.06.002_bib14","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1126\/science.aar4060","article-title":"Cancer immunotherapy using checkpoint blockade","volume":"359","author":"Ribas","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.cell.2026.06.002_bib15","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1038\/s41573-023-00809-z","article-title":"T cell receptor therapeutics: immunological targeting of the intracellular cancer proteome","volume":"22","author":"Klebanoff","year":"2023","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.cell.2026.06.002_bib16","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1016\/j.cell.2022.06.007","article-title":"Dissecting the treatment-naive ecosystem of human melanoma brain metastasis","volume":"185","author":"Biermann","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.cell.2026.06.002_bib17","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.cell.2018.11.043","article-title":"Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma","volume":"176","author":"Li","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.cell.2026.06.002_bib18","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.cell.2020.05.039","article-title":"Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma","volume":"182","author":"Ji","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.cell.2026.06.002_bib19","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1038\/s41591-019-0522-3","article-title":"Clonal replacement of tumor-specific T cells following PD-1 blockade","volume":"25","author":"Yost","year":"2019","journal-title":"Nat. Med."},{"key":"10.1016\/j.cell.2026.06.002_bib20","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with Harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat. Methods"},{"key":"10.1016\/j.cell.2026.06.002_bib21","doi-asserted-by":"crossref","DOI":"10.1126\/science.abl4896","article-title":"The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans","volume":"376","author":"The Tabula Sapiens Consortium","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.cell.2026.06.002_bib22","doi-asserted-by":"crossref","first-page":"D609","DOI":"10.1093\/nar\/gkae1010","article-title":"UniProt: the universal protein knowledgebase in 2025","volume":"53","author":"Bateman","year":"2025","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2026.06.002_bib23","doi-asserted-by":"crossref","DOI":"10.1126\/science.1260419","article-title":"Tissue-based map of the human proteome","volume":"347","author":"Uhl\u00e9n","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.cell.2026.06.002_bib24","doi-asserted-by":"crossref","first-page":"D1541","DOI":"10.1093\/nar\/gkab1026","article-title":"ProteomicsDB: toward a FAIR open-source resource for life-science research","volume":"50","author":"Lautenbacher","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2026.06.002_bib25","doi-asserted-by":"crossref","first-page":"D1467","DOI":"10.1093\/nar\/gkae1128","article-title":"Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery","volume":"53","author":"Buniello","year":"2025","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2026.06.002_bib26","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.674739","article-title":"The Role of GPNMB in Inflammation","volume":"12","author":"Saade","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cell.2026.06.002_bib27","doi-asserted-by":"crossref","first-page":"4573","DOI":"10.1038\/s41388-022-02443-2","article-title":"GPNMB: a potent inducer of immunosuppression in cancer","volume":"41","author":"Lazaratos","year":"2022","journal-title":"Oncogene"},{"key":"10.1016\/j.cell.2026.06.002_bib28","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.1200\/JCO.2013.52.5683","article-title":"Phase I\/II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Patients With Locally Advanced or Metastatic Breast Cancer","volume":"32","author":"Bendell","year":"2014","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.cell.2026.06.002_bib29","doi-asserted-by":"crossref","DOI":"10.3390\/cancers12082270","article-title":"A Phase II Study of Glembatumumab Vedotin for Metastatic Uveal Melanoma","volume":"12","author":"Hasanov","year":"2020","journal-title":"Cancers"},{"key":"10.1016\/j.cell.2026.06.002_bib30","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ejca.2019.08.015","article-title":"Phase II trial of the glycoprotein non-metastatic B-targeted antibody\u2013drug conjugate, glembatumumab vedotin (CDX-011), in recurrent osteosarcoma AOST1521: A report from the Children's Oncology Group","volume":"121","author":"Kopp","year":"2019","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.cell.2026.06.002_bib31","doi-asserted-by":"crossref","first-page":"3659","DOI":"10.1200\/JCO.2013.54.8115","article-title":"Phase I\/II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Patients With Advanced Melanoma","volume":"32","author":"Ott","year":"2014","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.cell.2026.06.002_bib32","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1002\/cncr.31892","article-title":"A phase 2 study of glembatumumab vedotin, an antibody-drug conjugate targeting glycoprotein NMB, in patients with advanced melanoma","volume":"125","author":"Ott","year":"2019","journal-title":"Cancer"},{"key":"10.1016\/j.cell.2026.06.002_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/s41523-021-00244-6","article-title":"Glembatumumab vedotin for patients with metastatic, gpNMB overexpressing, triple-negative breast cancer (\u201cMETRIC\u201d): a randomized multicenter study","volume":"7","author":"Vahdat","year":"2021","journal-title":"npj Breast Cancer"},{"key":"10.1016\/j.cell.2026.06.002_bib34","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1200\/JCO.2014.56.2959","article-title":"EMERGE: A Randomized Phase II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Advanced Glycoprotein NMB\u2013Expressing Breast Cancer","volume":"33","author":"Yardley","year":"2015","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.cell.2026.06.002_bib35","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1056\/NEJMoa1215134","article-title":"Chimeric Antigen Receptor\u2013Modified T Cells for Acute Lymphoid Leukemia","volume":"368","author":"Grupp","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cell.2026.06.002_bib36","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1056\/NEJMoa1103849","article-title":"Chimeric Antigen Receptor\u2013Modified T Cells in Chronic Lymphoid Leukemia","volume":"365","author":"Porter","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cell.2026.06.002_bib37","doi-asserted-by":"crossref","DOI":"10.1038\/bcj.2015.19","article-title":"A robust and rapid xenograft model to assess efficacy of chemotherapeutic agents for human acute myeloid leukemia","volume":"5","author":"Saland","year":"2015","journal-title":"Blood Cancer J."},{"key":"10.1016\/j.cell.2026.06.002_bib38","doi-asserted-by":"crossref","first-page":"3204","DOI":"10.4049\/jimmunol.0900269","article-title":"Elucidation of CXCR7-Mediated Signaling Events and Inhibition of CXCR4-Mediated Tumor Cell Transendothelial Migration by CXCR7 Ligands","volume":"183","author":"Zabel","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.cell.2026.06.002_bib39","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1126\/science.1174447","article-title":"A Gene Network Regulating Lysosomal Biogenesis and Function","volume":"325","author":"Sardiello","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.cell.2026.06.002_bib40","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1755-148X.2008.00518.x","article-title":"Gpnmb is a Melanoblast-Expressed, MITF-Dependent Gene","volume":"22","author":"Loftus","year":"2009","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.cell.2026.06.002_bib41","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/s41568-021-00344-2","article-title":"Autophagy in tumour immunity and therapy","volume":"21","author":"Xia","year":"2021","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.cell.2026.06.002_bib42","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/s41580-023-00585-z","article-title":"Autophagy and autophagy-related pathways in cancer","volume":"24","author":"Debnath","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.cell.2026.06.002_bib43","article-title":"Development and first-in-human CAR T therapy against the pathognomonic MiT-fusion driven protein GPNMB","author":"Zemp","year":"2025","journal-title":"medRxiv"},{"key":"10.1016\/j.cell.2026.06.002_bib45","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13059-017-1382-0","article-title":"SCANPY: large-scale single-cell gene expression data analysis","volume":"19","author":"Wolf","year":"2018","journal-title":"Genome Biol."},{"key":"10.1016\/j.cell.2026.06.002_bib46","doi-asserted-by":"crossref","first-page":"56","DOI":"10.25080\/Majora-92bf1922-00a","article-title":"Data structures for statistical computing in Python","author":"McKinney","year":"2010","journal-title":"SciPy"},{"key":"10.1016\/j.cell.2026.06.002_bib47","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/s41586-020-2649-2","article-title":"Array programming with NumPy","volume":"585","author":"Harris","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.cell.2026.06.002_bib48","doi-asserted-by":"crossref","first-page":"8249","DOI":"10.21105\/joss.08249","article-title":"gtexr: A convenient R interface to the Genotype-Tissue Expression (GTEx) Portal API","volume":"10","author":"Warwick","year":"2025","journal-title":"J. Open Source Softw."},{"key":"10.1016\/j.cell.2026.06.002_bib49","doi-asserted-by":"crossref","first-page":"e71","DOI":"10.1093\/nar\/gkv1507","article-title":"TCGAbiolinks: an R\/Bioconductor package for integrative analysis of TCGA data","volume":"44","author":"Colaprico","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.cell.2026.06.002_bib50","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.cell.2026.06.002_bib44","doi-asserted-by":"crossref","first-page":"6081","DOI":"10.1016\/j.cell.2021.11.016","article-title":"An NK-like CAR T cell transition in CAR T cell dysfunction","volume":"184","author":"Good","year":"2021","journal-title":"Cell"}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867426006513?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867426006513?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T13:08:05Z","timestamp":1783429685000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867426006513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":50,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0092867426006513"],"URL":"https:\/\/doi.org\/10.1016\/j.cell.2026.06.002","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cell.2026.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}