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In this study, calcium imaging and the whole\u2010cell patch\u2010clamp technique were used to investigate the role of Ca<jats:sup>2+<\/jats:sup> in basal acetylcholine (ACh) release in the <jats:italic>Xenopus<\/jats:italic> neuromuscular junction and in isolated myocytes exogenously loaded with ACh. Carried out in normal and Ca<jats:sup>2+<\/jats:sup>\u2010free extracellular solution, the results indicate that Ca<jats:sup>2+<\/jats:sup> near the release site is essential for basal neurotransmitter release.<\/jats:p>","DOI":"10.1016\/j.cellbi.2008.05.001","type":"journal-article","created":{"date-parts":[[2008,5,11]],"date-time":"2008-05-11T08:18:24Z","timestamp":1210493904000},"page":"1136-1142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Calcium near the release site is essential for basal ACh release in 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