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After hypoxic treatment, BMCs of apoptotic fraction were decreased. The expression of CXCR4 was noticeably increased in the hypoxia\u2010treated BMCs and their migration in response to SDF\u20101\u03b1 was enhanced compared with cells cultured under normoxic condition. Hypoxic BMCs had a higher degree of engraftment to the CCl<jats:sub>4<\/jats:sub>\u2010injured liver than the normoxic cells. Hypoxic treatment of BMCs may have merits in decreasing apoptosis of those cells as well as in enhancing cellular migration to SDF\u20101\u03b1, the chemokine which binds to BMCs expressed CXCR4 and to the injured tissue, such as CCl<jats:sub>4<\/jats:sub> damaged liver.<\/jats:p>","DOI":"10.1016\/j.cellbi.2008.10.002","type":"journal-article","created":{"date-parts":[[2008,10,28]],"date-time":"2008-10-28T15:33:37Z","timestamp":1225208017000},"page":"31-35","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effect of hypoxic treatment on bone marrow cells that are able to migrate to the injured liver"],"prefix":"10.1002","volume":"33","author":[{"given":"Sun\u2010Young","family":"Ju","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung\u2010Ah","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su 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