{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T16:59:14Z","timestamp":1758905954875,"version":"3.44.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Immunology"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.cellimm.2005.03.005","type":"journal-article","created":{"date-parts":[[2005,5,6]],"date-time":"2005-05-06T15:34:54Z","timestamp":1115393694000},"page":"41-52","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["The mouse immune response to human fibrinogen reveals an autoimmune component against mouse fibrinogen"],"prefix":"10.1016","volume":"233","author":[{"given":"Bent","family":"Rubin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Matron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cellimm.2005.03.005_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/eji.1830010102","article-title":"The somatic generation of immune recognition","volume":"1","author":"Jerne","year":"1971","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib2","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/S1074-7613(00)00080-7","article-title":"Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion","volume":"13","author":"Bouneaud","year":"2000","journal-title":"Immunity"},{"key":"10.1016\/j.cellimm.2005.03.005_bib3","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1093\/intimm\/10.12.1969","article-title":"Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic\/suppressive state","volume":"10","author":"Takahashi","year":"1998","journal-title":"Int. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib4","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/nri821","article-title":"CD4+CD25+ suppressor T cells: more questions than answers","volume":"2","author":"Shevach","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib5","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0165-5728(00)00218-6","article-title":"Residual public repertoires to self","volume":"107","author":"Wilson","year":"2000","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib6","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0092-8674(88)90567-3","article-title":"The molecular basis of blood coagulation","volume":"53","author":"Furie","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.cellimm.2005.03.005_bib7","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1182\/blood.V82.8.2414.2414","article-title":"Fibrin(ogen) is internalized and degraded by activated human monocytoid cells via Mac-1 (CD11b\/CD18): a nonplasmin fibrinolytic pathway","volume":"82","author":"Simon","year":"1993","journal-title":"Blood"},{"key":"10.1016\/j.cellimm.2005.03.005_bib8","doi-asserted-by":"crossref","first-page":"574","DOI":"10.4049\/jimmunol.166.1.574","article-title":"CD11b\/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression","volume":"166","author":"Perera","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib9","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.4049\/jimmunol.167.5.2887","article-title":"Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4","volume":"167","author":"Smiley","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib10","doi-asserted-by":"crossref","first-page":"4177","DOI":"10.4049\/jimmunol.166.6.4177","article-title":"The major synovial targets of rheumatoid arthritis-specific anti-filaggrin autoantibodies are deiminated forms of the \u03b1 and \u03b2 chains of fibrin","volume":"166","author":"Masson-Bessi\u00e8re","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib11","doi-asserted-by":"crossref","first-page":"585","DOI":"10.4049\/jimmunol.162.1.585","article-title":"The epitopes targeted by the rheumatoid arthritis-associated anti-fillagrin auto-antibodies are posttranslationally generated on various sites of (pro)-fillagrin by deimination of arginine residues","volume":"162","author":"Girbal-Neuheuser","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib12","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/ng1206","article-title":"Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis","volume":"34","author":"Suzuki","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.cellimm.2005.03.005_bib13","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1002\/art.11107","article-title":"Defects in the regulation of B cell apoptosis are required for the production of citrullinated peptide autoantibodies in mice","volume":"48","author":"Lopez-Hoyos","year":"2003","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cellimm.2005.03.005_bib14","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1002\/art.11229","article-title":"Citrullination of synovial proteins in murine models of rheumatoid arthritis","volume":"48","author":"Vossenaar","year":"2003","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cellimm.2005.03.005_bib15","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.0300-9475.2004.01457.x","article-title":"Citrullination of self-proteins and autoimmunity","volume":"60","author":"Rubin","year":"2004","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib16","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1172\/JCI1316","article-title":"Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies","volume":"101","author":"Schellekens","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cellimm.2005.03.005_bib17","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.4049\/jimmunol.140.4.1063","article-title":"T cell recognition of fibrinogen. A determinant on the A\u03b1 chain does not require processing","volume":"140","author":"Lee","year":"1978","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib18","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1084\/jem.20020619","article-title":"A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis","volume":"196","author":"Atsumi","year":"2002","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2005.03.005_bib19","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1002\/eji.1830161007","article-title":"Insulin-specific T cell help to TNP-specific B cells requires activation via the antigen T cell receptor","volume":"16","author":"Rubin","year":"1986","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib20","doi-asserted-by":"crossref","first-page":"5178","DOI":"10.4049\/jimmunol.157.11.5178","article-title":"Auto-antibodies to murine type II collagen in collagen-induced arthritis. A comparison of susceptible and non-susceptible strains","volume":"157","author":"Brand","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib21","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1600-065X.1990.tb00817.x","article-title":"Type II collagen autoimmunity in animals and provocations leading to arthritis","volume":"118","author":"Holmdahl","year":"1990","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cellimm.2005.03.005_bib22","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1002\/1529-0131(199907)42:7<1497::AID-ANR25>3.0.CO;2-#","article-title":"T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis-associated and nonassociated HLA-DR4 alleles","volume":"42","author":"Cope","year":"1999","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cellimm.2005.03.005_bib23","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1046\/j.1365-2249.2000.01174.x","article-title":"Complex pattern of Th1 and Th2 activation with a preferential increase of auto-reactive Th1 cells in BALB\/c mice with proteoglycan (aggrecan)-induced arthritis","volume":"120","author":"Hollo","year":"2000","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib24","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1084\/jem.20030091","article-title":"Activation of virus-specific memory B cells in the absence of T cell help","volume":"199","author":"Hebeis","year":"2004","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2005.03.005_bib25","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.4049\/jimmunol.163.6.3116","article-title":"Human rheumatoid factor production is dependent on CD40 signaling and autoantigen","volume":"163","author":"Kyburz","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib26","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1084\/jem.137.4.911","article-title":"The immune response to hapten-autologous protein conjugates in the mouse. III. Specificity of non-thymus processed (B) and thymus-processed (T) lymphocytes","volume":"137","author":"Rubin","year":"1973","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2005.03.005_bib27","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1002\/art.11063","article-title":"CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis","volume":"48","author":"Morgan","year":"2003","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cellimm.2005.03.005_bib28","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nri1149","article-title":"MHC-guided processing: binding of large antigen fragments","volume":"3","author":"Sercarz","year":"2003","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib29","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1084\/jem.20011941","article-title":"Arthritogenic monoclonal antibodies from K\/BxN mice","volume":"195","author":"Maccioni","year":"2002","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2005.03.005_bib30","doi-asserted-by":"crossref","first-page":"3764","DOI":"10.4049\/jimmunol.163.7.3764","article-title":"Cross-reactivity of myelin basic protein-specific T cells with multiple microbial peptides: experimental autoimmune encephalomyelitis induction in TCR transgenic mice","volume":"163","author":"Grogan","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib31","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1084\/jem.191.5.761","article-title":"High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of na\u00efve mice: mechanisms of selection of the self-reactive repertoire","volume":"191","author":"Anderson","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2005.03.005_bib32","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0952791502000031","article-title":"Cross priming or direct priming: Is that really the question?","volume":"15","author":"Norbury","year":"2003","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib33","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/S0952-7915(02)00009-2","article-title":"Epitope dominance, competition and T cell affinity maturation","volume":"15","author":"Kedl","year":"2003","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib34","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.4049\/jimmunol.167.3.1601","article-title":"Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis","volume":"167","author":"Wipke","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib35","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S1074-7613(02)00275-3","article-title":"Arthritis critically dependent on innate immune system players","volume":"16","author":"Ji","year":"2002","journal-title":"Immunity"},{"key":"10.1016\/j.cellimm.2005.03.005_bib36","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.4049\/jimmunol.169.6.3015","article-title":"Major differences in antigen-processing correlate with a single arg->lys sunstitution in HLA-DR molecules predisposing to rheumatoid arthritis and with their selective interactions with 70-kDa heat shock protein chaperones","volume":"169","author":"Roth","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib37","doi-asserted-by":"crossref","first-page":"181","DOI":"10.4049\/jimmunol.173.1.181","article-title":"The regulatory C-terminal determinants within mycobacterial heat shock protein 65 are cryptic and cross-reactive with the dominant self homologs: implications for the pathogenesis of autoimmune arthritis","volume":"173","author":"Durai","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib38","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1600-065X.1995.tb00073.x","article-title":"Tolerance induction as a therapeutic strategy for the control of autoimmune endocrine disease in mouse models","volume":"144","author":"Parish","year":"1995","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cellimm.2005.03.005_bib39","doi-asserted-by":"crossref","first-page":"9446","DOI":"10.1073\/pnas.1133443100","article-title":"Structural insights into the antigenecity of myelin oligodendrocyte glycoprotein","volume":"100","author":"Breithaupt","year":"2003","journal-title":"Proc. Natl. Acad. Sci USA"},{"key":"10.1016\/j.cellimm.2005.03.005_bib40","doi-asserted-by":"crossref","first-page":"7574","DOI":"10.1073\/pnas.95.13.7574","article-title":"Definition of MHC and T cell receptor contacts in the HLA-DR4 restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice","volume":"95","author":"Andersson","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cellimm.2005.03.005_bib41","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780301102","article-title":"The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis","volume":"30","author":"Gregersen","year":"1987","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cellimm.2005.03.005_bib42","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1600-065X.1999.tb01307.x","article-title":"HLA class II transgenic mice as models of human diseases","volume":"169","author":"Taneja","year":"1999","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cellimm.2005.03.005_bib43","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1038\/nm962","article-title":"Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo","volume":"3","author":"Millar","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.cellimm.2005.03.005_bib44","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0008-8749(85)90067-X","article-title":"On the molecular basis of T helper cell function. IV. B-lymphocyte promotor factors: on their mode of action, biochemical nature and possible relationship to molecules involved in specific T helper cell activity","volume":"92","author":"Reininger","year":"1985","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.cellimm.2005.03.005_bib45","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nri1569","article-title":"Consensual immunity: success-driven development of Th1 and Th2 responses","volume":"5","author":"Kalinski","year":"2005","journal-title":"Nat. Rev. Immunol."}],"container-title":["Cellular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874905000456?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874905000456?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T22:39:08Z","timestamp":1757803148000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008874905000456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0008874905000456"],"URL":"https:\/\/doi.org\/10.1016\/j.cellimm.2005.03.005","relation":{},"ISSN":["0008-8749"],"issn-type":[{"type":"print","value":"0008-8749"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The mouse immune response to human fibrinogen reveals an autoimmune component against mouse fibrinogen","name":"articletitle","label":"Article Title"},{"value":"Cellular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellimm.2005.03.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}