{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T03:22:50Z","timestamp":1791688970414,"version":"4.3.4"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Immunology"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.cellimm.2012.11.014","type":"journal-article","created":{"date-parts":[[2012,12,10]],"date-time":"2012-12-10T18:46:17Z","timestamp":1355165177000},"page":"92-100","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Boosting of nonspecific host response by aromatic spices turmeric and ginger in immunocompromised mice"],"prefix":"10.1016","volume":"280","author":[{"given":"Biswajit","family":"Chakraborty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahuya","family":"Sengupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cellimm.2012.11.014_b0005","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/ni1116","article-title":"Toll-like receptors in the pathogenesis of human disease","volume":"5","author":"Cook","year":"2004","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0010","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3390\/molecules17010191","article-title":"Chromone and flavonoid alkaloids: occurrence and bioactivity","volume":"17","author":"Khadem","year":"2011","journal-title":"Molecules"},{"key":"10.1016\/j.cellimm.2012.11.014_b0015","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1089\/107555303321223035","article-title":"Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa)","volume":"9","author":"Chainani-Wu","year":"2003","journal-title":"J. Altern. Complement. Med."},{"key":"10.1016\/j.cellimm.2012.11.014_b0020","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0944-7113(00)80048-3","article-title":"Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins I-Iii from Curcuma longa","volume":"7","author":"Ramsewak","year":"2000","journal-title":"Phytomedicine"},{"key":"10.1016\/j.cellimm.2012.11.014_b0130","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S2221-1691(11)60026-9","article-title":"Hepatoprotective and immunomodulatory properties of aqueous extract of Curcuma longa in carbon tetra chloride intoxicated swiss albino mice","author":"Sengupta","year":"2011","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"10.1016\/j.cellimm.2012.11.014_b0030","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1007\/s00018-008-7452-4","article-title":"Curcumin: from ancient medicine to current clinical trials","volume":"65","author":"Hatcher","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cellimm.2012.11.014_b0035","first-page":"414","article-title":"Zingiber officinale roscoe (ginger) as an adjuvant in cancer treatment: a review","volume":"16","author":"Pereira","year":"2011","journal-title":"J. Buon"},{"key":"10.1016\/j.cellimm.2012.11.014_b0040","first-page":"385","article-title":"Efficacy of zingiber officinale on third stage larvae and adult fecundity of musca domestica and anopheles pharoensis","volume":"38","author":"Abdel Halim","year":"2008","journal-title":"J. Egypt. Soc. Parasitol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0045","first-page":"251","article-title":"Studies on antimicrobial activities of solvent extracts of different spices","volume":"32","author":"Keskin","year":"2011","journal-title":"J. Environ. Biol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0135","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1002\/ptr.1335","volume":"17","author":"Ficker","year":"2003","journal-title":"Phytother. Res."},{"key":"10.1016\/j.cellimm.2012.11.014_b0055","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jnutbio.2007.05.008","article-title":"[6]-Gingerol inhibits metastasis of Mda-Mb-231 human breast cancer cells","volume":"19","author":"Lee","year":"2008","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.cellimm.2012.11.014_b0060","doi-asserted-by":"crossref","first-page":"139","DOI":"10.2131\/jts.27.139","article-title":"Hepatoprotective and immunomodulatory properties of tinospora cordifolia in CCL4 intoxicated mature albino rats","volume":"27","author":"Bishayi","year":"2002","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.cellimm.2012.11.014_b0065","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1472-6882-11-102","article-title":"Effect of aqueous extract of tinospora cordifolia on functions of peritoneal macrophages isolated from CCl4 intoxicated male albino mice","volume":"11","author":"Sengupta","year":"2011","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.cellimm.2012.11.014_b0070","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jep.2006.04.003","article-title":"Anti-infective potential of natural products: how to develop a stronger in vitro \u2018proof-of-concept\u2019","volume":"106","author":"Cos","year":"2006","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0075","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0041-008X(91)90296-Q","article-title":"Splenic cell targets in gallium arsenide-induced suppression of the primary antibody response","volume":"110","author":"Sikorski","year":"1991","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0140","doi-asserted-by":"crossref","first-page":"4133","DOI":"10.4049\/jimmunol.154.8.4133","article-title":"Lack of effect of recombinant platelet-derived growth factor on human neutrophil function","volume":"154","author":"Qu","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0085","first-page":"17","article-title":"A new rapid air-drying technique for scanning electron microscopy using tetramethylsilane: application to mammalian tissue","volume":"73","author":"Dey","year":"1993","journal-title":"Cytobios"},{"key":"10.1016\/j.cellimm.2012.11.014_b0090","doi-asserted-by":"crossref","first-page":"16189","DOI":"10.1074\/jbc.270.27.16189","article-title":"Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. a possible signaling role for the syk tyrosine kinase","volume":"270","author":"Lin","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cellimm.2012.11.014_b0095","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/jlb.35.2.193","article-title":"Killing of listeria monocytogenes by inflammatory neutrophils and mononuclear phagocytes from immune and nonimmune mice","volume":"35","author":"Czuprynski","year":"1984","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0150","series-title":"Handbook Of Experimental Immunology","first-page":"46.1","article-title":"In vitro determination of phagocytosis and intracellular killing by polymorphonuclear neutrophils and mononuclear phagocytes","author":"Leigh","year":"1986"},{"key":"10.1016\/j.cellimm.2012.11.014_b0105","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0005-2744(78)90197-3","article-title":"Characterization and quantification of the peroxidase in human monocytes","volume":"525","author":"Bos","year":"1978","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cellimm.2012.11.014_b0145","doi-asserted-by":"crossref","first-page":"8617","DOI":"10.1073\/pnas.97.15.8617","article-title":"Dynamic regulation of neuronal no synthase transcription by calcium influx through a creb family transcription factor-dependent mechanism","volume":"97","author":"Sasaki","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cellimm.2012.11.014_b0115","doi-asserted-by":"crossref","first-page":"6728","DOI":"10.4049\/jimmunol.166.11.6728","article-title":"TNF-alpha controls intracellular mycobacterial growth by both inducible nitric oxide synthase-dependent and inducible nitric oxide synthase-independent pathways","volume":"166","author":"Bekker","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0120","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1189\/jlb.0602325","article-title":"The many faces of macrophage activation","volume":"73","author":"Mosser","year":"2003","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.cellimm.2012.11.014_b0125","doi-asserted-by":"crossref","first-page":"e19105","DOI":"10.1371\/journal.pone.0019105","article-title":"Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis","volume":"6","author":"Herbst","year":"2011","journal-title":"PLoS ONE"}],"container-title":["Cellular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874912002158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874912002158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T22:49:53Z","timestamp":1757803793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008874912002158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0008874912002158"],"URL":"https:\/\/doi.org\/10.1016\/j.cellimm.2012.11.014","relation":{},"ISSN":["0008-8749"],"issn-type":[{"value":"0008-8749","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Boosting of nonspecific host response by aromatic spices turmeric and ginger in immunocompromised mice","name":"articletitle","label":"Article Title"},{"value":"Cellular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellimm.2012.11.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}