{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:49:37Z","timestamp":1792799377474,"version":"4.5.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["STE833\/11-1"],"award-info":[{"award-number":["STE833\/11-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["13-1"],"award-info":[{"award-number":["13-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["TR-SFB 156"],"award-info":[{"award-number":["TR-SFB 156"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Immunology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.cellimm.2016.07.009","type":"journal-article","created":{"date-parts":[[2016,7,16]],"date-time":"2016-07-16T18:24:05Z","timestamp":1468693445000},"page":"13-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Myeloid cells do not contribute to gender-dependent differences in disease outcome in murine cutaneous leishmaniasis"],"prefix":"10.1016","volume":"308","author":[{"given":"Michael R.","family":"Fischer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantin","family":"Kunz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Dietze-Schwonberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beate","family":"Lorenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"von Stebut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cellimm.2016.07.009_b0005","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/ddg.12595","article-title":"Leishmaniasis","volume":"13","author":"von Stebut","year":"2015","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"10.1016\/j.cellimm.2016.07.009_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1610-0379.2011.07820.x","article-title":"Diagnosis and therapy of cutaneous and mucocutaneous Leishmaniasis in Germany","volume":"9","author":"Boecken","year":"2011","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"10.1016\/j.cellimm.2016.07.009_b0015","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.trstmh.2011.10.012","article-title":"Clinical features and epidemiology of cutaneous leishmaniasis and Leishmania major\/HIV co-infection in Cameroon: results of a large cross-sectional study","volume":"106","author":"Ngouateu","year":"2012","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.cellimm.2016.07.009_b0020","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/exd.12646","article-title":"Impaired T-cell-dependent protection against Leishmania major infection in HIV-positive patients is associated with worsened disease outcome","volume":"24","author":"Ngouateu","year":"2015","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0025","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/nri933","article-title":"The immunology of susceptibility and resistance to Leishmania major in mice","volume":"2","author":"Sacks","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0030","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.0141-9838.2004.00710.x","article-title":"Hormonal and immunological mechanisms mediating sex differences in parasite infection","volume":"26","author":"Klein","year":"2004","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0035","doi-asserted-by":"crossref","first-page":"A479","DOI":"10.1016\/j.autrev.2011.11.022","article-title":"The influence of sex and gender on the immune response","volume":"11","author":"Oertelt-Prigione","year":"2012","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.cellimm.2016.07.009_b0040","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1126\/science.283.5406.1277","article-title":"A gender gap in autoimmunity","volume":"283","author":"Whitacre","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.cellimm.2016.07.009_b0045","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1017\/S0031182000058303","article-title":"Sex differences and cross-immunity in DBA\/2 mice infected with L. mexicana and L. major","volume":"96","author":"Alexander","year":"1988","journal-title":"Parasitology"},{"key":"10.1016\/j.cellimm.2016.07.009_b0050","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1365-3024.1986.tb00831.x","article-title":"Sex-influenced response in the pathogenesis of cutaneous leishmaniasis in mice","volume":"8","author":"Giannini","year":"1986","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0055","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.1128\/iai.56.12.3316-3319.1988","article-title":"Hormonal modulation of sex differences in resistance to Leishmania major systemic infections","volume":"56","author":"Mock","year":"1988","journal-title":"Infect. Immun."},{"key":"10.1016\/j.cellimm.2016.07.009_b0060","doi-asserted-by":"crossref","first-page":"7251","DOI":"10.4049\/jimmunol.178.11.7251","article-title":"Dendritic cell-derived IL-12p40 homodimer contributes to susceptibility in cutaneous leishmaniasis in BALB\/c mice","volume":"178","author":"Nigg","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0065","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1084\/jem.188.10.1941","article-title":"Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva and saliva preexposure on the long-term outcome of Leishmania major infection in the mouse ear dermis","volume":"188","author":"Belkaid","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2016.07.009_b0070","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1084\/jem.20052288","article-title":"Uptake of Leishmania major by dendritic cells is mediated by Fcgamma receptors and facilitates acquisition of protective immunity","volume":"203","author":"Woelbing","year":"2006","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2016.07.009_b0075","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/978-1-62703-227-8_26","article-title":"Animal model for cutaneous leishmaniasis","volume":"961","author":"Fischer","year":"2012","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0080","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1182\/blood-2002-03-0921","article-title":"Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1alpha \/beta released from neutrophils recruited by mast cell-derived TNFalpha","volume":"101","author":"von Stebut","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.cellimm.2016.07.009_b0085","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1084\/jem.20102318","article-title":"Langerhans cells are negative regulators of the anti-Leishmania response","volume":"208","author":"Kautz-Neu","year":"2011","journal-title":"J. Exp. Med."},{"issue":"194","key":"10.1016\/j.cellimm.2016.07.009_b0090","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1084\/jem.194.10.1497","article-title":"The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure","volume":"208","author":"Belkaid","year":"2001","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2016.07.009_b0095","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s00430-012-0261-2","article-title":"Dendritic cells in Leishmania major infections: mechanisms of parasite uptake, cell activation and evidence for physiological relevance","volume":"201","author":"Kautz-Neu","year":"2012","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0100","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1084\/jem.183.2.515","article-title":"Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice","volume":"183","author":"Carrera","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2016.07.009_b0105","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1002\/(SICI)1521-4141(199804)28:04<1389::AID-IMMU1389>3.0.CO;2-1","article-title":"Analysis of cytokine production by inflammatory mouse macrophages at the single-cell level: selective impairment of IL-12 induction in Leishmania-infected cells","volume":"28","author":"Belkaid","year":"1998","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0110","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/pim.12049","article-title":"Leishmania major inhibits IL-12 in macrophages by signalling through CR3 (CD11b\/CD18) and down-regulation of ETS-mediated transcription","volume":"35","author":"Ricardo-Carter","year":"2013","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0115","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1084\/jem.188.8.1547","article-title":"Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity","volume":"188","author":"von Stebut","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2016.07.009_b0120","doi-asserted-by":"crossref","first-page":"3039","DOI":"10.4049\/jimmunol.0713598","article-title":"IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice","volume":"182","author":"Lopez Kostka","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0125","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1128\/CMR.14.3.476-488.2001","article-title":"Sex-associated hormones and immunity to protozoan parasites","volume":"14","author":"Roberts","year":"2001","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.cellimm.2016.07.009_b0130","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00005-011-0124-3","article-title":"Gender specific differences in the immune response to infection","volume":"59","author":"McClelland","year":"2011","journal-title":"Arch. Immunol. Ther. Exp. (Warsz)"},{"key":"10.1016\/j.cellimm.2016.07.009_b0135","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1749-6632.2012.06632.x","article-title":"Sex steroids, immune system, and parasitic infections: facts and hypotheses","volume":"1262","author":"Nava-Castro","year":"2012","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.cellimm.2016.07.009_b0140","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/nrmicro2608","article-title":"Leishmaniasis: complexity at the host-pathogen interface","volume":"9","author":"Kaye","year":"2011","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.cellimm.2016.07.009_b0145","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1084\/jem.20030159","article-title":"Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB\/c mice","volume":"198","author":"von Stebut","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2016.07.009_b0150","doi-asserted-by":"crossref","first-page":"e1000871","DOI":"10.1371\/journal.ppat.1000871","article-title":"Keratinocytes determine Th1 immunity during early experimental leishmaniasis","volume":"6","author":"Ehrchen","year":"2010","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.cellimm.2016.07.009_b0155","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1038\/ni725","article-title":"IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB\/c mice","volume":"2","author":"Biedermann","year":"2001","journal-title":"Nat. Immunol."}],"container-title":["Cellular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874916300582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874916300582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T22:54:35Z","timestamp":1757804075000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008874916300582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":31,"alternative-id":["S0008874916300582"],"URL":"https:\/\/doi.org\/10.1016\/j.cellimm.2016.07.009","relation":{},"ISSN":["0008-8749"],"issn-type":[{"value":"0008-8749","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Myeloid cells do not contribute to gender-dependent differences in disease outcome in murine cutaneous leishmaniasis","name":"articletitle","label":"Article Title"},{"value":"Cellular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellimm.2016.07.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}