{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T09:58:52Z","timestamp":1778752732447,"version":"3.51.4"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK-99-013"],"award-info":[{"award-number":["DK-99-013"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005368","name":"American Geosciences Institute","doi-asserted-by":"publisher","award":["2014A-FSC2"],"award-info":[{"award-number":["2014A-FSC2"]}],"id":[{"id":"10.13039\/100005368","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Immunology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.cellimm.2017.08.002","type":"journal-article","created":{"date-parts":[[2017,8,21]],"date-time":"2017-08-21T03:00:39Z","timestamp":1503284439000},"page":"43-52","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Mechanism of chimeric vaccine stimulation of indoleamine 2,3-dioxygenase biosynthesis in human dendritic cells is independent of TGF-\u03b2 signaling"],"prefix":"10.1016","volume":"319","author":[{"given":"Grace E.","family":"Esebanmen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William H.R.","family":"Langridge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.cellimm.2017.08.002_b0005","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/ni0901-777","article-title":"Sex differences in autoimmune disease","volume":"2","author":"Whitacre","year":"2001","journal-title":"Nat. Immunol."},{"issue":"3","key":"10.1016\/j.cellimm.2017.08.002_b0010","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/cmi.2010.70","article-title":"Explosion of autoimmune diseases and the mosaic of old and novel factors","volume":"8","author":"Agmon-Levin","year":"2011","journal-title":"Cell. Mol. Immunol."},{"issue":"4","key":"10.1016\/j.cellimm.2017.08.002_b0015","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.jaut.2012.05.001","article-title":"Criteria for environmentally associated autoimmune diseases","volume":"39","author":"Miller","year":"2012","journal-title":"J. Autoimmun."},{"issue":"2","key":"10.1016\/j.cellimm.2017.08.002_b0020","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s12016-013-8400-0","article-title":"NK cell trafficking in health and autoimmunity: a comprehensive review","volume":"47","author":"Peng","year":"2014","journal-title":"Clin. Rev. Allerg. Immunol."},{"key":"10.1016\/j.cellimm.2017.08.002_b0025","doi-asserted-by":"crossref","first-page":"569","DOI":"10.3389\/fimmu.2015.00569","article-title":"Tolerogenic dendritic cells for regulatory T cell induction in man","volume":"6","author":"Raker","year":"2015","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.cellimm.2017.08.002_b0030","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/icb.2013.73","article-title":"Dendritic cells treated with chloroquine modulate experimental autoimmune encephalomyelitis","volume":"92","author":"Thome","year":"2014","journal-title":"Immunol. Cell Biol."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0035","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1146\/annurev-immunol-020711-074929","article-title":"Molecular control of steady-state dendritic cell maturation and immune homeostasis","volume":"31","author":"Hammer","year":"2013","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.cellimm.2017.08.002_b0040","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3389\/fimmu.2015.00535","article-title":"Role of dendritic cells in the induction of lymphocyte tolerance","volume":"6","author":"Osorio","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cellimm.2017.08.002_b0045","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/B978-0-12-380995-7.00004-5","article-title":"How tolerogenic dendritic cells induce regulatory T cells","volume":"108","author":"Maldonado","year":"2010","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.cellimm.2017.08.002_b0050","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2013.00415","article-title":"Dendritic cell subsets in type 1 diabetes: friend or foe?","volume":"4","author":"Morel","year":"2013","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0055","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/ar4130","article-title":"Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis","volume":"15","author":"Thomas","year":"2013","journal-title":"Arthritis Res. Ther."},{"issue":"10","key":"10.1016\/j.cellimm.2017.08.002_b0060","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/nbt1098-934","article-title":"A plant-based cholera toxin B subunit-insulin fusion protein protects against the development of autoimmune diabetes","volume":"16","author":"Arakawa","year":"1998","journal-title":"Nat. Biotechnol."},{"issue":"2","key":"10.1016\/j.cellimm.2017.08.002_b0065","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1046\/j.1365-2249.2002.01988.x","article-title":"Nasal administration of CTB-insulin induces active tolerance against autoimmune diabetes in non-obese diabetic (NOD) mice","volume":"130","author":"Aspord","year":"2002","journal-title":"Clin. Exp. Immunol."},{"issue":"3","key":"10.1016\/j.cellimm.2017.08.002_b0070","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1385\/MB:34:3:317","article-title":"Suppression of hyperglycemia in NOD mice after inoculation with recombinant vaccinia viruses","volume":"34","author":"D\u00e9nes","year":"2006","journal-title":"Mol. Biotechnol."},{"issue":"4","key":"10.1016\/j.cellimm.2017.08.002_b0075","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.imbio.2010.09.008","article-title":"Suppression of dendritic cell activation by diabetes autoantigens linked to the cholera toxin B subunit","volume":"216","author":"Odumosu","year":"2011","journal-title":"Immunobiology"},{"issue":"2","key":"10.1016\/j.cellimm.2017.08.002_b0080","doi-asserted-by":"crossref","first-page":"e0118562","DOI":"10.1371\/journal.pone.0118562","article-title":"Induction of indoleamine 2,3-dioxygenase in human dendritic cells by a cholera toxin B subunit\u2014proinsulin vaccine","volume":"10","author":"Mbongue","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.cellimm.2017.08.002_b0085","doi-asserted-by":"crossref","first-page":"738","DOI":"10.3109\/08820139.2012.676122","article-title":"Indoleamine 2,3-Dioxygenase and Dendritic Cell Tolerogenicity","volume":"41","author":"Harden","year":"2012","journal-title":"Immunological investigations"},{"issue":"8","key":"10.1016\/j.cellimm.2017.08.002_b0090","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1002\/eji.201242572","article-title":"Indoleamine 2,3-dioxygenase: from catalyst to signaling function","volume":"42","author":"Fallarino","year":"2012","journal-title":"Eur. J. Immunol."},{"issue":"5","key":"10.1016\/j.cellimm.2017.08.002_b0095","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.immuni.2005.03.013","article-title":"GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase","volume":"22","author":"Munn","year":"2005","journal-title":"Immunity"},{"issue":"7","key":"10.1016\/j.cellimm.2017.08.002_b0100","doi-asserted-by":"crossref","first-page":"3596","DOI":"10.4049\/jimmunol.164.7.3596","article-title":"Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation","volume":"164","author":"Hwu","year":"2000","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.cellimm.2017.08.002_b0105","doi-asserted-by":"crossref","first-page":"e74551","DOI":"10.1371\/journal.pone.0074551","article-title":"HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation","volume":"8","author":"Plan\u00e8s","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.cellimm.2017.08.002_b0110","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1182\/blood-2008-11-191197","article-title":"Indoleamine 2,3-dioxygenase\u2013expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells","volume":"114","author":"Chung","year":"2009","journal-title":"Blood"},{"issue":"15","key":"10.1016\/j.cellimm.2017.08.002_b0115","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.1182\/blood-2008-12-195073","article-title":"Interferon-\u03b3-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells","volume":"114","author":"J\u00fcrgens","year":"2009","journal-title":"Blood"},{"issue":"5","key":"10.1016\/j.cellimm.2017.08.002_b0120","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/nrc3500","article-title":"Beyond TGF\u03b2: roles of other TGF\u03b2 superfamily members in cancer","volume":"13","author":"Wakefield","year":"2013","journal-title":"Nat. Rev. Cancer"},{"issue":"3","key":"10.1016\/j.cellimm.2017.08.002_b0125","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1093\/humupd\/dmv058","article-title":"Activins in reproductive biology and beyond","volume":"22","author":"Wijayarathna","year":"2016","journal-title":"Hum. Reprod. Update"},{"issue":"17","key":"10.1016\/j.cellimm.2017.08.002_b0130","doi-asserted-by":"crossref","first-page":"2934","DOI":"10.2174\/13816128113199990591","article-title":"TGF-beta signaling in cancer treatment","volume":"20","author":"Isabel","year":"2014","journal-title":"Curr. Pharm. Des."},{"issue":"5","key":"10.1016\/j.cellimm.2017.08.002_b0135","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a021873","article-title":"TGF-\u03b2 and the TGF-\u03b2 family: context-dependent roles in cell and tissue physiology","volume":"8","author":"Morikawa","year":"2016","journal-title":"Cold Spring Harbor Perspect. Biol."},{"issue":"22","key":"10.1016\/j.cellimm.2017.08.002_b0140","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1242\/dev.030338","article-title":"The regulation of TGFbeta signal transduction","volume":"136","author":"Moustakas","year":"2009","journal-title":"Development"},{"key":"10.1016\/j.cellimm.2017.08.002_b0145","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1146\/annurev.biochem.67.1.753","article-title":"TGF-beta signal transduction","volume":"67","author":"Massague","year":"1998","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.cellimm.2017.08.002_b0150","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1471-2148-9-28","article-title":"Emergence, development and diversification of the TGF-\u03b2 signalling pathway within the animal kingdom","volume":"9","author":"Huminiecki","year":"2009","journal-title":"BMC Evol. Biol."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0155","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/wdev.86","article-title":"The TGFbeta superfamily signaling pathway","volume":"2","author":"Weiss","year":"2013","journal-title":"Wiley Interdiscip. Rev.: Dev. Biol."},{"issue":"10","key":"10.1016\/j.cellimm.2017.08.002_b0160","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/nrm3434","article-title":"TGF\u03b2 signalling in context","volume":"13","author":"Massagu\u00e9","year":"2012","journal-title":"Nat. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.imlet.2006.12.010","article-title":"The role of TGF-\u03b2 superfamily during T cell development: new insights","volume":"109","author":"Licona-Lim\u00f3n","year":"2007","journal-title":"Immunol. Lett."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0170","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/eji.200939618","article-title":"Synergistic effect of TGF-\u03b2 superfamily members on the induction of Foxp3+ regulatory T cells(1)","volume":"40","author":"Lu","year":"2010","journal-title":"Eur. J. Immunol."},{"issue":"3","key":"10.1016\/j.cellimm.2017.08.002_b0175","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.4049\/jimmunol.1301487","article-title":"Activin A as a mediator of NK\u2013dendritic cell functional interactions","volume":"192","author":"Seeger","year":"2014","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.cellimm.2017.08.002_b0180","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1182\/blood-2007-03-080994","article-title":"Activin-A: a novel dendritic cell\u2013derived cytokine that potently attenuates CD40 ligand\u2013specific cytokine and chemokine production","volume":"111","author":"Robson","year":"2007","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0185","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/eji.201343535","article-title":"Nodal promotes the generation of M2-like macrophages and downregulates the expression of IL-12","volume":"44","author":"Wang","year":"2014","journal-title":"Eur. J. Immunol."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0190","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.immunol.24.021605.090737","article-title":"Transforming growth factor-\u03b2 regulation of immune responses","volume":"24","author":"Li","year":"2006","journal-title":"Annu. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0195","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1006\/jaut.1999.0339","article-title":"The inhibitory effects of transforming growth factor-beta-1 (TGF-\u03b21) in autoimmune diseases","volume":"14","author":"Prud'homme","year":"2000","journal-title":"J. Autoimmun."},{"issue":"7","key":"10.1016\/j.cellimm.2017.08.002_b0200","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.autrev.2005.03.006","article-title":"Transforming growth factor \u03b2 (TGF-\u03b2) and autoimmunity","volume":"4","author":"Aoki","year":"2005","journal-title":"Autoimmun. Rev."},{"issue":"2","key":"10.1016\/j.cellimm.2017.08.002_b0205","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s11926-006-0054-y","article-title":"Transforming growth factor-\u03b2: recent advances on its role in immune tolerance","volume":"8","author":"Kriegel","year":"2006","journal-title":"Curr. Rheumatol. Rep."},{"issue":"3","key":"10.1016\/j.cellimm.2017.08.002_b0210","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1083\/jcb.200109100","article-title":"The integrin \u03b1v\u03b28 mediates epithelial homeostasis through MT1-MMP\u2013dependent activation of TGF-\u03b21","volume":"157","author":"Mu","year":"2002","journal-title":"J. Cell Biol."},{"issue":"12","key":"10.1016\/j.cellimm.2017.08.002_b0215","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.imbio.2012.06.009","article-title":"Regulation of TGF\u03b2 in the immune system: an emerging role for integrins and dendritic cells","volume":"217","author":"Worthington","year":"2012","journal-title":"Immunobiology"},{"issue":"8\u20139","key":"10.1016\/j.cellimm.2017.08.002_b0220","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.ejcb.2008.01.012","article-title":"Integrins and the activation of latent transforming growth factor \u03b21 \u2013 an intimate relationship","volume":"87","author":"Wipff","year":"2008","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.cellimm.2017.08.002_b0225","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1146\/annurev-immunol-032713-120257","article-title":"TGF-\u03b2 activation and function in immunity","volume":"32","author":"Travis","year":"2014","journal-title":"Annu. Rev. Immunol."},{"issue":"20","key":"10.1016\/j.cellimm.2017.08.002_b0230","doi-asserted-by":"crossref","first-page":"411","DOI":"10.21037\/atm.2016.10.33","article-title":"\u03b1v\u03b21 integrin as a novel therapeutic target for tissue fibrosis","volume":"4","author":"Song","year":"2016","journal-title":"Ann. Transl. Med."},{"issue":"6","key":"10.1016\/j.cellimm.2017.08.002_b0235","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1083\/jcb.200611044","article-title":"Absence of integrin-mediated TGF\u03b21 activation in vivo recapitulates the phenotype of TGF\u03b21-null mice","volume":"176","author":"Yang","year":"2007","journal-title":"J. Cell Biol."},{"issue":"7160","key":"10.1016\/j.cellimm.2017.08.002_b0240","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/nature06110","article-title":"Loss of integrin \u03b1(v)\u03b2(8) on dendritic cells causes autoimmunity and colitis in mice","volume":"449","author":"Travis","year":"2007","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.cellimm.2017.08.002_b0245","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.immuni.2015.04.012","article-title":"Integrin \u03b1v\u03b28-mediated TGF-\u03b2 activation by effector regulatory T cells is essential for suppression of T-cell-mediated inflammation","volume":"42","author":"Worthington John","year":"2015","journal-title":"Immunity"},{"issue":"8","key":"10.1016\/j.cellimm.2017.08.002_b0250","doi-asserted-by":"crossref","first-page":"5194","DOI":"10.4049\/jimmunol.181.8.5194","article-title":"Cutting edge: autocrine TGF-\u03b2 sustains default tolerogenesis by IDO-competent dendritic cells","volume":"181","author":"Belladonna","year":"2008","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.cellimm.2017.08.002_b0255","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1038\/ni.2077","article-title":"Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells","volume":"12","author":"Pallotta","year":"2011","journal-title":"Nat. Immunol."},{"issue":"2","key":"10.1016\/j.cellimm.2017.08.002_b0260","doi-asserted-by":"crossref","first-page":"e0147509","DOI":"10.1371\/journal.pone.0147509","article-title":"Chimeric vaccine stimulation of human dendritic cell indoleamine 2,3-dioxygenase occurs via the non-canonical NF-\u03baB pathway","volume":"11","author":"Kim","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.cellimm.2017.08.002_b0265","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1615\/JEnvironPatholToxicolOncol.v28.i2.30","article-title":"Small interfering RNAs (siRNAs) targeting TGF-\u03b2(1) mRNA suppress asbestos-induced expression of TGF-\u03b2(1) and CTGF in fibroblasts","volume":"28","author":"Lai","year":"2009","journal-title":"J. Environ. Pathol. Toxicol. Oncol."},{"issue":"10","key":"10.1016\/j.cellimm.2017.08.002_b0270","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1111\/jcmm.12360","article-title":"Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes","volume":"18","author":"Pallotta","year":"2014","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.cellimm.2017.08.002_b0275","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1242\/jcs.035246","article-title":"Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice","volume":"122","author":"Aluwihare","year":"2009","journal-title":"J. Cell. Sci."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1677\/JOE-08-0549","article-title":"The biology of activin: recent advances in structure, regulation and function","volume":"202","author":"Xia","year":"2009","journal-title":"J. Endocrinol."},{"issue":"6","key":"10.1016\/j.cellimm.2017.08.002_b0285","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/icb.2015.7","article-title":"The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology","volume":"93","author":"Hardy","year":"2015","journal-title":"Immunol. Cell Biol."},{"issue":"19","key":"10.1016\/j.cellimm.2017.08.002_b0290","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1161\/01.CIR.0000165133.84978.E2","article-title":"Angiotensin II activates the smad pathway in vascular smooth muscle cells by a transforming growth factor-\u03b2\u2013independent mechanism","volume":"111","author":"Rodr\u00edguez-Vita","year":"2005","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.cellimm.2017.08.002_b0295","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1161\/HYPERTENSIONAHA.109.136531","article-title":"Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor\u2013\u03b2\u2013dependent and \u2013independent smad pathways","volume":"54","author":"Yang","year":"2009","journal-title":"Hypertension"},{"issue":"5","key":"10.1016\/j.cellimm.2017.08.002_b0300","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.stem.2009.09.012","article-title":"A small molecule inhibitor of Tgf-\u03b2 signaling replaces Sox2 in reprogramming by inducing Nanog","volume":"5","author":"Ichida","year":"2009","journal-title":"Cell Stem Cell"},{"issue":"18","key":"10.1016\/j.cellimm.2017.08.002_b0305","doi-asserted-by":"crossref","first-page":"4494","DOI":"10.1021\/jm0400247","article-title":"Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-\u03b2 type I receptor inhibitors","volume":"47","author":"Gellibert","year":"2004","journal-title":"J. Med. Chem."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0310","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1124\/mol.62.1.65","article-title":"SB-431542 is a potent and specific inhibitor of transforming growth factor-\u03b2 superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7","volume":"62","author":"Inman","year":"2002","journal-title":"Mol. Pharmacol."},{"issue":"4","key":"10.1016\/j.cellimm.2017.08.002_b0315","doi-asserted-by":"crossref","first-page":"360","DOI":"10.3109\/08820139.2013.879172","article-title":"TGF-\u03b2 favors bone marrow-derived dendritic cells to acquire tolerogenic properties","volume":"43","author":"Song","year":"2014","journal-title":"Immunol. Invest."},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0320","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00441-011-1201-y","article-title":"Non-smad signaling pathways","volume":"347","author":"Mu","year":"2012","journal-title":"Cell Tissue Res."},{"issue":"6958","key":"10.1016\/j.cellimm.2017.08.002_b0325","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/nature02006","article-title":"Smad-dependent and Smad-independent pathways in TGF-[beta] family signalling","volume":"425","author":"Derynck","year":"2003","journal-title":"Nature"},{"issue":"9","key":"10.1016\/j.cellimm.2017.08.002_b0330","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/ni.1919","article-title":"Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel","volume":"11","author":"Schmidt","year":"2010","journal-title":"Nat. Immunol."},{"issue":"2","key":"10.1016\/j.cellimm.2017.08.002_b0335","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/imm.12442","article-title":"Effect of enterohaemorrhagic Escherichia coli O157:H7-specific enterohaemolysin on interleukin-1\u03b2 production differs between human and mouse macrophages due to the different sensitivity of NLRP3 activation","volume":"145","author":"Cheng","year":"2015","journal-title":"Immunology"},{"issue":"7","key":"10.1016\/j.cellimm.2017.08.002_b0340","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1084\/jem.20050463","article-title":"Tumor cells convert immature myeloid dendritic cells into TGF-\u03b2\u2013secreting cells inducing CD4(+)CD25(+) regulatory T cell proliferation","volume":"202","author":"Ghiringhelli","year":"2005","journal-title":"J. Exp. Med."},{"issue":"7","key":"10.1016\/j.cellimm.2017.08.002_b0345","doi-asserted-by":"crossref","first-page":"e102390","DOI":"10.1371\/journal.pone.0102390","article-title":"TGF-\u03b2 signaling initiated in dendritic cells instructs suppressive effects on Th17 differentiation at the site of neuroinflammation","volume":"9","author":"Speck","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0350","doi-asserted-by":"crossref","first-page":"73","DOI":"10.4049\/jimmunol.156.1.73","article-title":"TGF-beta contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice","volume":"156","author":"Maeda","year":"1996","journal-title":"J. Immunol."},{"issue":"1\u20132","key":"10.1016\/j.cellimm.2017.08.002_b0355","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.cytogfr.2005.09.004","article-title":"TGF-beta as a T cell regulator in colitis and colon cancer","volume":"17","author":"Becker","year":"2006","journal-title":"Cytokine Growth Factor Rev."},{"issue":"5","key":"10.1016\/j.cellimm.2017.08.002_b0360","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1053\/j.gastro.2011.06.076","article-title":"Preferential expression of integrin \u03b1v\u03b28 promotes generation of regulatory T cells by mouse CD103+ dendritic cells","volume":"141","author":"Pa\u00efdassi","year":"2011","journal-title":"Gastroenterology"},{"issue":"5","key":"10.1016\/j.cellimm.2017.08.002_b0365","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1053\/j.gastro.2011.06.057","article-title":"Intestinal dendritic cells specialize to activate transforming growth factor-\u03b2 and induce Foxp3(+) regulatory T cells via integrin \u03b1v\u03b28","volume":"141","author":"Worthington","year":"2011","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.cellimm.2017.08.002_b0370","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1385\/MB:32:1:001","article-title":"Bacterial and plant enterotoxin B subunit-autoantigen fusion proteins suppress diabetes insulitis","volume":"32","author":"Carter","year":"2006","journal-title":"Mol. Biotechnol."}],"container-title":["Cellular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874917301223?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874917301223?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T22:55:43Z","timestamp":1757804143000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008874917301223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":74,"alternative-id":["S0008874917301223"],"URL":"https:\/\/doi.org\/10.1016\/j.cellimm.2017.08.002","relation":{},"ISSN":["0008-8749"],"issn-type":[{"value":"0008-8749","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mechanism of chimeric vaccine stimulation of indoleamine 2,3-dioxygenase biosynthesis in human dendritic cells is independent of TGF-\u03b2 signaling","name":"articletitle","label":"Article Title"},{"value":"Cellular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellimm.2017.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}