{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:49:46Z","timestamp":1785880186555,"version":"3.56.0"},"reference-count":129,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Anusandhan National Research Foundation","doi-asserted-by":"publisher","award":["SRG\/2022\/001547"],"award-info":[{"award-number":["SRG\/2022\/001547"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Immunology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.cellimm.2026.105129","type":"journal-article","created":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T06:45:45Z","timestamp":1782542745000},"page":"105129","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Exosome-mediated immune modulation in rheumatoid arthritis and its role in synovial inflammation and autoimmune amplification"],"prefix":"10.1016","volume":"426","author":[{"given":"Bharathi","family":"Kalidass","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirith","family":"Murugesan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusuya","family":"Shanmugam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveen Kumar","family":"Kaveri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh Kumar","family":"Lakshmanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cellimm.2026.105129_bb0005","article-title":"Rheumatoid arthritis: pathogenesis and therapeutic advances","volume":"5","author":"Gao","year":"2024","journal-title":"MedComm (Beijing)"},{"key":"10.1016\/j.cellimm.2026.105129_bb0010","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.0105-2896.2009.00859.x","article-title":"Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis","volume":"233","author":"Bartok","year":"2010","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cellimm.2026.105129_bb0015","doi-asserted-by":"crossref","unstructured":"H. Liang, J. Liu, From inflammatory activation to fibrotic remodeling: the central role of macrophage heterogeneity in frozen shoulder, Front. Immunol. Volume 17-2026 (2026). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2026.1732435.","DOI":"10.3389\/fimmu.2026.1732435"},{"key":"10.1016\/j.cellimm.2026.105129_bb0020","doi-asserted-by":"crossref","DOI":"10.3390\/jcm14186409","article-title":"Pathogenic role of cytokines in rheumatoid arthritis","volume":"14","author":"Fujimoto","year":"2025","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.cellimm.2026.105129_bb0025","first-page":"603","article-title":"Angiogenesis in rheumatoid arthritis: pathological characterization, pathogenic mechanisms, and nano-targeted therapeutic strategies","volume":"50","author":"Zhao","year":"2025","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.cellimm.2026.105129_bb0030","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s41927-017-0001-8","article-title":"Cytokines in the pathogenesis of rheumatoid arthritis: new players and therapeutic targets","volume":"1","author":"Alunno","year":"2017","journal-title":"BMC Rheumatol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0035","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1007\/s11357-025-02049-y","article-title":"Geroscience insights into difficult-to-treat rheumatoid arthritis: the role of unhealthy aging, comorbidity, and therapeutic complexity","volume":"48","author":"Lehoczki","year":"2026","journal-title":"Geroscience"},{"key":"10.1016\/j.cellimm.2026.105129_bb0040","first-page":"228","article-title":"Exosomes: intriguing mediators of intercellular communication in the organism's response to noxious agents","volume":"75","author":"Vu\u010demilovi\u0107","year":"2024","journal-title":"Arch. Ind. Hyg. Toxicol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0045","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s12929-023-00964-w","article-title":"Exosomal miRNA-mediated intercellular communications and immunomodulatory effects in tumor microenvironments","volume":"30","author":"Nail","year":"2023","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0050","article-title":"Extracellular vesicles as tools and targets in therapy for diseases","volume":"9","author":"Kumar","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.cellimm.2026.105129_bb0055","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s10238-026-02072-z","article-title":"Extracellular matrix remodeling in the pathogenesis and therapeutic strategies of rheumatoid arthritis","volume":"26","author":"Yang","year":"2026","journal-title":"Clin. Exp. Med."},{"key":"10.1016\/j.cellimm.2026.105129_bb0060","article-title":"Advances in immune cell-based therapeutic agents for the treatment of inflammation-related diseases","author":"Yang","year":"2026","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.cellimm.2026.105129_bb0065","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26115101","article-title":"HIF-1\u03b1-mediated disruption of cellular junctions: the impact of hypoxia on the tumor microenvironment and invasion","volume":"26","author":"Springer","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0070","article-title":"Exosomes as cellular communicators and therapeutic agents in orthopedic diseases: from mechanisms to intervention","volume":"21","author":"Zhang","year":"2026","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.cellimm.2026.105129_bb0075","doi-asserted-by":"crossref","unstructured":"Q. Zheng, Y. Zhai, Y. Wang, Z. Pan, The role of hypoxic microenvironment in rheumatoid arthritis, Front. Immunol. Volume 16-2025 (2025). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2025.1633406.","DOI":"10.3389\/fimmu.2025.1633406"},{"key":"10.1016\/j.cellimm.2026.105129_bb0080","doi-asserted-by":"crossref","DOI":"10.1007\/s10238-025-01979-3","article-title":"Regulatory roles of non-coding and exosomal RNAs in colorectal cancer: spotlight on angiogenesis","volume":"26","author":"Moeinfar","year":"2025","journal-title":"Clin. Exp. Med."},{"key":"10.1016\/j.cellimm.2026.105129_bb0085","article-title":"Inflammatory fibroblast-like Synoviocyte-derived exosomes aggravate osteoarthritis via enhancing macrophage glycolysis","volume":"11","author":"Liu","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0090","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1136\/ard.47.4.348","article-title":"Synovial lining cell hyperplasia in rheumatoid arthritis: dogma and fact","volume":"47","author":"Henderson","year":"1988","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.cellimm.2026.105129_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2025.107649","article-title":"The role of HIF-1\u03b1 in hypoxic metabolic reprogramming in osteoarthritis","volume":"213","author":"Zhang","year":"2025","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.cellimm.2026.105129_bb0100","doi-asserted-by":"crossref","DOI":"10.3390\/cells14090673","article-title":"The distinct role of HIF-1\u03b1 and HIF-2\u03b1 in hypoxia and angiogenesis","volume":"14","author":"Bakleh","year":"2025","journal-title":"Cells"},{"key":"10.1016\/j.cellimm.2026.105129_bb0105","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1186\/s10020-025-01378-0","article-title":"Bioenergetics of cancer cells: insights into the Warburg effect and regulation of ATP synthase","volume":"31","author":"Del Dotto","year":"2025","journal-title":"Mol. Med."},{"key":"10.1016\/j.cellimm.2026.105129_bb0110","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s00018-025-06073-1","article-title":"The role of lactate on arthritis-associated cells: physiology, pathology, and therapeutic strategies","volume":"83","author":"Chen","year":"2026","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0115","doi-asserted-by":"crossref","unstructured":"X. Jin, N. Zhang, T. Yan, J. Wei, L. Hao, C. Sun, H. Zhao, S. Jiang, Lactate-mediated metabolic reprogramming of tumor-associated macrophages: implications for tumor progression and therapeutic potential, Front. Immunol. Volume 16-2025 (2025). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2025.1573039.","DOI":"10.3389\/fimmu.2025.1573039"},{"key":"10.1016\/j.cellimm.2026.105129_bb0120","doi-asserted-by":"crossref","unstructured":"V. Pucino, M. Nefla, V. Gauthier, G. Alsaleh, S.A. Clayton, J. Marshall, A. Filer, A.R. Clark, K. Raza, C.D. Buckley, Differential effect of lactate on synovial fibroblast and macrophage effector functions, Front. Immunol. Volume 14-2023 (2023). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2023.1183825.","DOI":"10.3389\/fimmu.2023.1183825"},{"key":"10.1016\/j.cellimm.2026.105129_bb0125","doi-asserted-by":"crossref","DOI":"10.3390\/cells10123311","article-title":"Acidic and hypoxic microenvironment in melanoma: impact of tumour exosomes on disease progression","volume":"10","author":"Boussadia","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.cellimm.2026.105129_bb0130","doi-asserted-by":"crossref","DOI":"10.1038\/s41401-025-01520-y","article-title":"HIF-1\u03b1 mediates mitochondrial damage by down-regulating ALKBH7 expression to promote the aberrant activation of FLS in rheumatoid arthritis","volume":"46","author":"Wang","year":"2025","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.cellimm.2026.105129_bb0135","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jot.2023.05.004","article-title":"HIF-1\u03b1 dependent RhoA as a novel therapeutic target to regulate rheumatoid arthritis fibroblast-like synoviocytes migration in vitro and in vivo","volume":"40","author":"Chen","year":"2023","journal-title":"J. Orthop. Translat."},{"key":"10.1016\/j.cellimm.2026.105129_bb0140","doi-asserted-by":"crossref","first-page":"3807","DOI":"10.1021\/acs.nanolett.4c05782","article-title":"Biomimetic nanoparticles inhibit the HIF-1\u03b1\/iNOS\/NLRP3 pathway to alleviate rheumatoid arthritis","volume":"25","author":"Chen","year":"2025","journal-title":"Nano Lett."},{"key":"10.1016\/j.cellimm.2026.105129_bb0145","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1186\/1471-2407-12-421","article-title":"Hypoxic enhancement of exosome release by breast cancer cells","volume":"12","author":"King","year":"2012","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cellimm.2026.105129_bb0150","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23020905","article-title":"Rheumatoid arthritis: pathogenic roles of diverse immune cells","volume":"23","author":"Jang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0155","article-title":"Macrophage signaling pathways in health and disease: from bench to bedside applications","volume":"6","author":"Chi","year":"2025","journal-title":"MedComm (Beijing)"},{"key":"10.1016\/j.cellimm.2026.105129_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2026.108194","article-title":"Metabolic control of immunity and inflammation: mitochondrial dynamics, pharmacological targets, and therapeutic opportunities","volume":"227","author":"Wang","year":"2026","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.cellimm.2026.105129_bb0165","doi-asserted-by":"crossref","unstructured":"S. Zhang, Z. Duan, F. Liu, Q. Wu, X. Sun, H. Ma, The impact of exosomes derived from distinct sources on rheumatoid arthritis, Front. Immunol. Volume 14-2023 (2023). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2023.1240747.","DOI":"10.3389\/fimmu.2023.1240747"},{"key":"10.1016\/j.cellimm.2026.105129_bb0170","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00296-026-06073-9","article-title":"The joint-local renin\u2013angiotensin system in rheumatoid arthritis and osteoarthritis: mechanistic evidence, disease-specific patterns, and translational perspectives","volume":"46","author":"Bilgin","year":"2026","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.cellimm.2026.105129_bb0175","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/549412","article-title":"Hypoxia-inducible Factor-1 in physiological and pathophysiological angiogenesis: applications and therapies","volume":"2015","author":"Zimna","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.cellimm.2026.105129_bb0180","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13317-020-00145-x","article-title":"Transformation of fibroblast-like synoviocytes in rheumatoid arthritis; from a friend to foe","volume":"12","author":"Mousavi","year":"2021","journal-title":"Autoimmun. Highlights"},{"key":"10.1016\/j.cellimm.2026.105129_bb0185","doi-asserted-by":"crossref","DOI":"10.3390\/cells8020121","article-title":"MicroRNAs at the interface between osteogenesis and angiogenesis as targets for bone regeneration","volume":"8","author":"Fr\u00f6hlich","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.cellimm.2026.105129_bb0190","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1152\/physrev.00059.2009","article-title":"Role of Rab GTPases in membrane traffic and cell physiology","volume":"91","author":"Hutagalung","year":"2011","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cellimm.2026.105129_bb0195","doi-asserted-by":"crossref","unstructured":"D. Guo, J. Yan, Z. Yang, M. Chen, W. Zhong, X. Yuan, S. Yu, The immune regulatory role of exosomal miRNAs and their clinical application potential in heart failure, Front. Immunol. Volume 15-2024 (2024). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2024.1476865.","DOI":"10.3389\/fimmu.2024.1476865"},{"key":"10.1016\/j.cellimm.2026.105129_bb0200","doi-asserted-by":"crossref","unstructured":"Q. Liu, L. He, X. Wu, X. Pan, Extracellular vesicles in rheumatoid arthritis: emerging roles in progression, diagnosis, and therapeutic development, Front. Immunol. Volume 17-2026 (2026). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2026.1748591.","DOI":"10.3389\/fimmu.2026.1748591"},{"key":"10.1016\/j.cellimm.2026.105129_bb0205","doi-asserted-by":"crossref","DOI":"10.3390\/cells13181586","article-title":"The contribution of macrophage plasticity to inflammatory arthritis and their potential as therapeutic targets","volume":"13","author":"Kulakova","year":"2024","journal-title":"Cells"},{"key":"10.1016\/j.cellimm.2026.105129_bb0210","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jacbts.2024.06.003","article-title":"Emerging role of macrophage-fibroblast interactions in cardiac homeostasis and remodeling","volume":"10","author":"Xu-Zhe","year":"2025","journal-title":"JACC Basic Transl. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0215","article-title":"Targeting GM-CSF in rheumatoid arthritis: advances in cytokine-directed immunotherapy and clinical implications","volume":"15","author":"Garc\u00eda-Dom\u00ednguez","year":"2025","journal-title":"JACC Basic Transl. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0220","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1038\/s41591-020-0939-8","article-title":"Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis","volume":"26","author":"Alivernini","year":"2020","journal-title":"Nat. Med."},{"key":"10.1016\/j.cellimm.2026.105129_bb0225","article-title":"Loss of synovial tissue macrophage homeostasis precedes rheumatoid arthritis clinical onset","volume":"10","author":"Hanlon","year":"2026","journal-title":"Sci. Adv."},{"key":"10.1016\/j.cellimm.2026.105129_bb0230","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1016\/j.ard.2025.07.019","article-title":"Spatial mapping of rheumatoid arthritis synovial niches reveals a LYVE1+ macrophage network associated with response to therapy","volume":"84","author":"De Lima","year":"2025","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.cellimm.2026.105129_bb0235","article-title":"Spatial transcriptomics reveals immune-stromal crosstalk within the synovium of patients with juvenile idiopathic arthritis","volume":"11","author":"Inamo","year":"2025","journal-title":"JCI Insight"},{"key":"10.1016\/j.cellimm.2026.105129_bb0240","article-title":"Macrophage plasticity: signaling pathways, tissue repair, and regeneration","volume":"5","author":"Yan","year":"2024","journal-title":"MedComm (Beijing)"},{"key":"10.1016\/j.cellimm.2026.105129_bb0245","doi-asserted-by":"crossref","unstructured":"M. Cutolo, R. Campitiello, E. Gotelli, S. Soldano, The role of M1\/M2 macrophage polarization in rheumatoid arthritis synovitis, Front. Immunol. Volume 13-2022 (2022). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2022.867260.","DOI":"10.3389\/fimmu.2022.867260"},{"key":"10.1016\/j.cellimm.2026.105129_bb0250","doi-asserted-by":"crossref","unstructured":"M. Zhang, L. Wan, X. Zhang, S. Wang, F. Li, D. Yan, Exosome circ-CBLB promotes M1 macrophage polarization in rheumatoid arthritis through the TLR3\/TRAF3 signaling axis, Front. Immunol. Volume 16-2025 (2025). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2025.1627389.","DOI":"10.3389\/fimmu.2025.1627389"},{"key":"10.1016\/j.cellimm.2026.105129_bb0255","doi-asserted-by":"crossref","DOI":"10.1111\/1756-185X.70167","article-title":"Unraveling the dual role of circ-CBLB and ETS-1 in rheumatoid arthritis: biomarkers and therapeutic targets","volume":"28","author":"Li","year":"2025","journal-title":"Int. J. Rheum. Dis."},{"key":"10.1016\/j.cellimm.2026.105129_bb0260","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/iub.2410","article-title":"m6A methyltransferase Wilms' tumor 1-associated protein facilitates cell proliferation and cisplatin resistance in NK\/T cell lymphoma by regulating dual-specificity phosphatases 6 expression via m6A RNA methylation","volume":"73","author":"Ma","year":"2021","journal-title":"IUBMB Life"},{"key":"10.1016\/j.cellimm.2026.105129_bb0265","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/s00018-024-05299-9","article-title":"WTAP and m6A-modified circRNAs modulation during stress response in acute myeloid leukemia progenitor cells","volume":"81","author":"Iaiza","year":"2024","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0270","doi-asserted-by":"crossref","unstructured":"D. Yan, L. Wan, WTAP modulates macrophage polarization in rheumatoid arthritis by targeting exosomal circ-CBLB via m6A modification, Front. Immunol. Volume 16-2025 (2025). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2025.1601259.","DOI":"10.3389\/fimmu.2025.1601259"},{"key":"10.1016\/j.cellimm.2026.105129_bb0275","doi-asserted-by":"crossref","unstructured":"L. Lu, M. Shi, W. Qin, M. Yang, X. Wang, Y. Wang, Immunometabolic programming of macrophages in asthma pathogenesis and therapy, Front. Physiol. Volume 16-2025 (2026). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fphys.2025.1736340.","DOI":"10.3389\/fphys.2025.1736340"},{"key":"10.1016\/j.cellimm.2026.105129_bb0280","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1186\/s40001-025-02618-z","article-title":"Dual role of miR-155 and exosomal miR-155 in tumor angiogenesis: implications for cancer progression and therapy","volume":"30","author":"Hussain","year":"2025","journal-title":"Eur. J. Med. Res."},{"key":"10.1016\/j.cellimm.2026.105129_bb0285","doi-asserted-by":"crossref","first-page":"11193","DOI":"10.1073\/pnas.1019536108","article-title":"MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis","volume":"108","author":"Kurowska-Stolarska","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0290","doi-asserted-by":"crossref","unstructured":"S. Alivernini, E. Gremese, C. McSharry, B. Tolusso, G. Ferraccioli, I.B. McInnes, M. Kurowska-Stolarska, MicroRNA-155\u2014at the critical interface of innate and adaptive immunity in arthritis, Front. Immunol. Volume 8-2017 (2018). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2017.01932.","DOI":"10.3389\/fimmu.2017.01932"},{"key":"10.1016\/j.cellimm.2026.105129_bb0295","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26146935","article-title":"The Inositol-5-phosphatase SHIP1: expression, regulation and role in acute lymphoblastic leukemia","volume":"26","author":"Ehm","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0300","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/eji.201646795","article-title":"Regulation of immune cell signaling by SHIP1: a phosphatase, scaffold protein, and potential therapeutic target","volume":"47","author":"Pauls","year":"2017","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0305","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1016\/j.ymthe.2019.07.003","article-title":"Peripheral circulating exosome-mediated delivery of miR-155 as a novel mechanism for acute lung inflammation","volume":"27","author":"Jiang","year":"2019","journal-title":"Mol. Ther."},{"key":"10.1016\/j.cellimm.2026.105129_bb0310","doi-asserted-by":"crossref","first-page":"148","DOI":"10.5607\/en.2014.23.2.148","article-title":"Suppression of miR-155 expression in IFN-\u03b3-treated astrocytes and microglia by DJ-1: a possible mechanism for maintaining SOCS1 expression","volume":"23","author":"Kim","year":"2014","journal-title":"Exp. Neurobiol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0315","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1189\/jlb.1110644","article-title":"Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function","volume":"90","author":"Whyte","year":"2011","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0320","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1002\/art.23386","article-title":"Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis","volume":"58","author":"Stanczyk","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cellimm.2026.105129_bb0325","doi-asserted-by":"crossref","first-page":"7385","DOI":"10.4049\/jimmunol.176.12.7385","article-title":"A membrane form of TNF-\u03b1 presented by exosomes delays T cell activation-induced cell Death1","volume":"176","author":"Zhang","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0330","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12929-017-0398-9","article-title":"Preclinical and clinical aspects of TNF-\u03b1 and its receptors TNFR1 and TNFR2 in breast cancer","volume":"24","author":"Mart\u00ednez-Reza","year":"2017","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0335","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14112603","article-title":"Tumor necrosis factor receptor 2 (TNFR2): An emerging target in Cancer therapy","volume":"14","author":"Medler","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.cellimm.2026.105129_bb0340","article-title":"Harnessing and enhancing macrophage phagocytosis for cancer therapy","volume":"12","author":"Chen","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0345","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/imr.13278","article-title":"Specialized pro-resolving mediators enhance the clearance of dead cells","volume":"319","author":"Fredman","year":"2023","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cellimm.2026.105129_bb0350","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1545625","article-title":"Regulation of the innate immune response in rheumatoid arthritis","volume":"16","author":"Muheremu","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0355","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.905356","article-title":"Synovial macrophages: past life, current situation, and application in inflammatory arthritis","volume":"13","author":"Bai","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0360","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/s41586-019-1471-1","article-title":"Locally renewing resident synovial macrophages provide a protective barrier for the joint","volume":"572","author":"Culemann","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.cellimm.2026.105129_bb0365","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1186\/s12967-025-07346-w","article-title":"Macrophage-centred crosstalk with infiltrating immune cells in rheumatoid arthritis and its regulation by mesenchymal stem cells","volume":"23","author":"Zheng","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.cellimm.2026.105129_bb0370","author":"Yuan"},{"key":"10.1016\/j.cellimm.2026.105129_bb0375","article-title":"Signaling pathways in macrophages: molecular mechanisms and therapeutic targets","volume":"4","author":"Li","year":"2023","journal-title":"MedComm (Beijing)"},{"key":"10.1016\/j.cellimm.2026.105129_bb0380","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/s41392-023-01452-1","article-title":"Macrophages in immunoregulation and therapeutics","volume":"8","author":"Chen","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.cellimm.2026.105129_bb0385","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2402226121","article-title":"Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses","volume":"121","author":"Metwally","year":"2024","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0390","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202200128R","article-title":"Macrophage programming is regulated by a cooperative interaction between fatty acid binding protein 5 and peroxisome proliferator-activated receptor \u03b3","volume":"36","author":"El Kharbili","year":"2022","journal-title":"FASEB J."},{"key":"10.1016\/j.cellimm.2026.105129_bb0395","doi-asserted-by":"crossref","DOI":"10.1155\/2008\/546753","article-title":"PPAR alpha regulation of the immune response and autoimmune encephalomyelitis","volume":"2008","author":"Yang","year":"2008","journal-title":"PPAR Res."},{"key":"10.1016\/j.cellimm.2026.105129_bb0400","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.immuni.2010.11.009","article-title":"STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells","volume":"33","author":"Szanto","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.cellimm.2026.105129_bb0405","article-title":"STAT6 signaling mediates PPAR\u03b3 activation and resolution of acute sterile inflammation in mice","volume":"10","author":"Lee","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.cellimm.2026.105129_bb0410","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/8917804","article-title":"Macrophage polarization in chronic inflammatory diseases: killers or builders?","volume":"2018","author":"Parisi","year":"2018","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.cellimm.2026.105129_bb0415","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/245804","article-title":"IRF5 is a specific marker of inflammatory macrophages in vivo","volume":"2013","author":"Weiss","year":"2013","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.cellimm.2026.105129_bb0420","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12935-025-04105-1","article-title":"Exosomal regulation of cellular reprogramming and polarization in the tumor microenvironment","volume":"26","author":"Bayat","year":"2025","journal-title":"Cancer Cell Int."},{"key":"10.1016\/j.cellimm.2026.105129_bb0425","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s11926-025-01180-1","article-title":"T cell dysregulation in rheumatoid arthritis: from genetic susceptibility to established disease","volume":"27","author":"Chin","year":"2025","journal-title":"Curr. Rheumatol. Rep."},{"key":"10.1016\/j.cellimm.2026.105129_bb0430","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/751793","article-title":"Altered Immunoregulation in rheumatoid arthritis: the role of regulatory T cells and Proinflammatory Th17 cells and therapeutic implications","volume":"2015","author":"Alunno","year":"2015","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.cellimm.2026.105129_bb0435","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1007\/s12015-023-10586-2","article-title":"Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming","volume":"19","author":"Hyland","year":"2023","journal-title":"Stem Cell Rev. Rep."},{"key":"10.1016\/j.cellimm.2026.105129_bb0440","doi-asserted-by":"crossref","unstructured":"Y. Zhou, G. Ran, H. Guo, Exosome-delivered bioactive molecules regulate macrophage polarization in atherosclerosis and myocardial infarction: mechanisms and therapeutic potential, Front. Cardiovasc. Med. Volume 13-2026 (2026). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fcvm.2026.1739907.","DOI":"10.3389\/fcvm.2026.1739907"},{"key":"10.1016\/j.cellimm.2026.105129_bb0445","doi-asserted-by":"crossref","unstructured":"G.M. Bidgood, N. Keating, K. Doggett, S.E. Nicholson, SOCS1 is a critical checkpoint in immune homeostasis, inflammation and tumor immunity, Front. Immunol. Volume 15-2024 (2024). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2024.1419951.","DOI":"10.3389\/fimmu.2024.1419951"},{"key":"10.1016\/j.cellimm.2026.105129_bb0450","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.4049\/jimmunol.1302467","article-title":"A negative feedback loop mediated by STAT3 limits human Th17 responses","volume":"193","author":"Purvis","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0455","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/s12276-024-01376-y","article-title":"mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction","volume":"57","author":"Lee","year":"2025","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.cellimm.2026.105129_bb0460","doi-asserted-by":"crossref","DOI":"10.1016\/j.omtn.2023.102041","article-title":"A mutual regulatory loop between miR-155 and SOCS1 influences renal inflammation and diabetic kidney disease","volume":"34","author":"Prieto","year":"2023","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.cellimm.2026.105129_bb0465","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1002\/art.30570","article-title":"The response of T cells to interleukin-6 is differentially regulated by the microenvironment of the rheumatoid synovial fluid and tissue","volume":"63","author":"Hidalgo","year":"2011","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cellimm.2026.105129_bb0470","article-title":"STAT3 pathway in cancers: past, present, and future","volume":"3","author":"Wang","year":"2022","journal-title":"MedComm (Beijing)"},{"key":"10.1016\/j.cellimm.2026.105129_bb0475","doi-asserted-by":"crossref","unstructured":"M. Jiang, W. Zhang, P. Liu, W. Yu, T. Liu, J. Yu, Dysregulation of SOCS-mediated negative feedback of cytokine signaling in carcinogenesis and its significance in cancer treatment, Front. Immunol. Volume 8-2017 (2017). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2017.00070.","DOI":"10.3389\/fimmu.2017.00070"},{"key":"10.1016\/j.cellimm.2026.105129_bb0480","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.it.2021.09.005","article-title":"RORγt protein modifications and IL-17-mediated inflammation","volume":"42","author":"Kumar","year":"2021","journal-title":"Trends Immunol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0485","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1182\/blood.V91.9.3308","article-title":"gp130, the cytokine common signal-transducer of Interleukin-6 cytokine family, is downregulated in T cells in vivo by Interleukin-6","volume":"91","author":"Wang","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.cellimm.2026.105129_bb0490","author":"Miao"},{"key":"10.1016\/j.cellimm.2026.105129_bb0495","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2315123121","article-title":"IL-6\/gp130 signaling in CD4+ T cells drives the pathogenesis of pulmonary hypertension","volume":"121","author":"Ishibashi","year":"2024","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0500","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1084\/jem.20071397","article-title":"Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model","volume":"204","author":"Hirota","year":"2007","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cellimm.2026.105129_bb0505","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116440","article-title":"Exploring the therapeutic potential of regulatory T cell in rheumatoid arthritis: insights into subsets, markers, and signaling pathways","volume":"174","author":"Su","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.cellimm.2026.105129_bb0510","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s12943-020-01234-1","article-title":"Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects","volume":"19","author":"Li","year":"2020","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.cellimm.2026.105129_bb0515","doi-asserted-by":"crossref","unstructured":"H. Wang, Y. Zhang, C. Zhang, Y. Zhao, J. Shu, X. Tang, Exosomes derived from miR-146a-overexpressing fibroblast-like synoviocytes in cartilage degradation and macrophage M1 polarization: a novel protective agent for osteoarthritis?, Front. Immunol. Volume 15-2024 (2024). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2024.1361606.","DOI":"10.3389\/fimmu.2024.1361606"},{"key":"10.1016\/j.cellimm.2026.105129_bb0520","doi-asserted-by":"crossref","unstructured":"N. Rusca, S. Monticelli, MiR-146a in immunity and disease, Mol. Biol. Int. 2011 (2011) 437301. doi:https:\/\/doi.org\/10.4061\/2011\/437301.","DOI":"10.4061\/2011\/437301"},{"key":"10.1016\/j.cellimm.2026.105129_bb0525","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/imr.12059","article-title":"Regulation of miRNA biogenesis and turnover in the immune system","volume":"253","author":"Bronevetsky","year":"2013","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cellimm.2026.105129_bb0530","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2026.116173","article-title":"MiR-146a-armed exosomes reverse immunosuppressive networks in NSCLC by dual-targeting of MYD88\/STAT3 and PD-L1 axes","volume":"172","author":"Alimohammadi","year":"2026","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0535","doi-asserted-by":"crossref","unstructured":"K. Mukherjee, S.N. Bhattacharyya, The role of miRNAs in the development of super-Tregs as a potential therapy for neurodegenerative diseases, Front. Immunol. Volume 17-2026 (2026). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2026.1708031.","DOI":"10.3389\/fimmu.2026.1708031"},{"key":"10.1016\/j.cellimm.2026.105129_bb0540","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2014.525","article-title":"MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K\/AKT\/mTOR activation in lymphoid malignancies","volume":"6","author":"Choudhary","year":"2015","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.cellimm.2026.105129_bb0545","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13071543","article-title":"Apoptosis-inducing TNF superfamily ligands for Cancer therapy","volume":"13","author":"Diaz Arguello","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.cellimm.2026.105129_bb0550","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2024.119688","article-title":"TRAIL-induced apoptosis and proteasomal activity \u2013 mechanisms, signalling and interplay","volume":"1871","author":"Boccellato","year":"2024","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Cell Res."},{"key":"10.1016\/j.cellimm.2026.105129_bb0555","doi-asserted-by":"crossref","DOI":"10.3390\/cells8020154","article-title":"Role of exosomes in the regulation of T-cell mediated immune responses and in autoimmune disease","volume":"8","author":"Anel","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.cellimm.2026.105129_bb0560","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1186\/ar1010","article-title":"Roles of B cells in rheumatoid arthritis","volume":"5","author":"Silverman","year":"2003","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.cellimm.2026.105129_bb0565","doi-asserted-by":"crossref","first-page":"687","DOI":"10.3390\/vaccines11030687","article-title":"Exosomes as rheumatoid arthritis diagnostic biomarkers and therapeutic agents","volume":"11","author":"Heydari","year":"2023","journal-title":"Vaccines (Basel)."},{"key":"10.1016\/j.cellimm.2026.105129_bb0570","doi-asserted-by":"crossref","unstructured":"F. Wu, J. Gao, J. Kang, X. Wang, Q. Niu, J. Liu, L. Zhang, B cells in rheumatoid arthritis: pathogenic mechanisms and treatment prospects, Front. Immunol. Volume 12-2021 (2021). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2021.750753.","DOI":"10.3389\/fimmu.2021.750753"},{"key":"10.1016\/j.cellimm.2026.105129_bb0575","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1365-2567.2004.02075.x","article-title":"How do follicular dendritic cells interact intimately with B cells in the germinal Centre?","volume":"114","author":"Park","year":"2005","journal-title":"Immunology"},{"key":"10.1016\/j.cellimm.2026.105129_bb0580","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/s41593-025-02153-4","article-title":"Extracellular matrix proteolysis maintains synapse plasticity during brain development","volume":"29","author":"Nakajo","year":"2026","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cellimm.2026.105129_bb0585","doi-asserted-by":"crossref","unstructured":"A.N. Suthers, S. Sarantopoulos, TLR7\/TLR9- and B cell receptor-signaling crosstalk: promotion of potentially dangerous B cells, Front. Immunol. Volume 8-2017 (2017). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2017.00775.","DOI":"10.3389\/fimmu.2017.00775"},{"key":"10.1016\/j.cellimm.2026.105129_bb0590","doi-asserted-by":"crossref","unstructured":"C. Ge, B. Xu, B. Liang, E. L\u00f6nnblom, S.L. Lundstr\u00f6m, R.A. Zubarev, B. Ayoglu, P. Nilsson, T. Skogh, A. Kastbom, V. Malmstr\u00f6m, L. Klareskog, R.E.M. Toes, T. Rispens, D. Dobritzsch, R. Holmdahl, Structural basis of cross-reactivity of anti\u2013citrullinated protein antibodies, Arthritis Rheumatol. 71 (2019) 210\u2013221. doi:https:\/\/doi.org\/10.1002\/art.40698, Arthritis Rheumatol.","DOI":"10.1002\/art.40698"},{"key":"10.1016\/j.cellimm.2026.105129_bb0595","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.117390","article-title":"Exploring the influence of non-coding RNAs on NF-\u03baB signaling pathway regulation in ulcerative colitis","volume":"179","author":"Pourmehran","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.cellimm.2026.105129_bb0600","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1002\/eji.200324133","article-title":"Mini-review activation-induced cytidine deaminase: a dual role in class-switch recombination and somatic hypermutation","volume":"33","author":"Durandy","year":"2003","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.cellimm.2026.105129_bb0605","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/j.celrep.2017.01.050","article-title":"BCR and endosomal TLR signals synergize to increase AID expression and establish central B cell tolerance","volume":"18","author":"Kuraoka","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.cellimm.2026.105129_bb0610","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/s41419-023-05991-x","article-title":"Apoptotic exosome-like vesicles transfer specific and functional mRNAs to endothelial cells by phosphatidylserine-dependent macropinocytosis","volume":"14","author":"Brodeur","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.cellimm.2026.105129_bb0615","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/s41419-022-04591-5","article-title":"Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes","volume":"13","author":"Beillevaire","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.cellimm.2026.105129_bb0620","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtauto.2024.100250","article-title":"Vascular injury derived apoptotic exosome-like vesicles trigger autoimmunity","volume":"9","author":"Juillard","year":"2024","journal-title":"J. Transl. Autoimmun."},{"key":"10.1016\/j.cellimm.2026.105129_bb0625","doi-asserted-by":"crossref","unstructured":"T. Duan, Y. Du, C. Xing, H.Y. Wang, R.-F. Wang, Toll-like receptor signaling and its role in cell-mediated immunity, Front. Immunol. Volume 13-2022 (2022). https:\/\/doi.org\/https:\/\/doi.org\/10.3389\/fimmu.2022.812774.","DOI":"10.3389\/fimmu.2022.812774"},{"key":"10.1016\/j.cellimm.2026.105129_bb0630","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/ajt.15082","article-title":"New insights into immune mechanisms of antiperlecan\/LG3 antibody production: importance of T cells and innate B1 cells","volume":"19","author":"Padet","year":"2019","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.cellimm.2026.105129_bb0635","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1002\/art.22276","article-title":"Association of citrullinated proteins with synovial exosomes","volume":"54","author":"Skriner","year":"2006","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cellimm.2026.105129_bb0640","doi-asserted-by":"crossref","first-page":"R132","DOI":"10.1186\/ar3070","article-title":"Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins","volume":"12","author":"Van Steendam","year":"2010","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.cellimm.2026.105129_bb0645","doi-asserted-by":"crossref","DOI":"10.1002\/cti2.1185","article-title":"Proteomic analysis of extracellular vesicles reveals an immunogenic cargo in rheumatoid arthritis synovial fluid","volume":"9","author":"Foers","year":"2020","journal-title":"Clin. Transl. Immunology"}],"container-title":["Cellular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874926000699?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0008874926000699?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:22:31Z","timestamp":1785878551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0008874926000699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":129,"alternative-id":["S0008874926000699"],"URL":"https:\/\/doi.org\/10.1016\/j.cellimm.2026.105129","relation":{},"ISSN":["0008-8749"],"issn-type":[{"value":"0008-8749","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exosome-mediated immune modulation in rheumatoid arthritis and its role in synovial inflammation and autoimmune amplification","name":"articletitle","label":"Article Title"},{"value":"Cellular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellimm.2026.105129","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105129"}}