{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:54:24Z","timestamp":1791500064514,"version":"4.3.4"},"reference-count":118,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019531","name":"Science Fund for Distinguished Young Scholars of Chongqing Municipality","doi-asserted-by":"publisher","award":["CSTB2025NSCQ-JQYXZZXMX0006"],"award-info":[{"award-number":["CSTB2025NSCQ-JQYXZZXMX0006"]}],"id":[{"id":"10.13039\/501100019531","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32471213"],"award-info":[{"award-number":["32471213"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32501043"],"award-info":[{"award-number":["32501043"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32271208"],"award-info":[{"award-number":["32271208"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010905","name":"Major Research Plan of National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92557302"],"award-info":[{"award-number":["92557302"]}],"id":[{"id":"10.13039\/501100010905","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["#2023ZD0507800"],"award-info":[{"award-number":["#2023ZD0507800"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016834","name":"Chongqing Municipal Health Commission","doi-asserted-by":"publisher","award":["HBRC202405"],"award-info":[{"award-number":["HBRC202405"]}],"id":[{"id":"10.13039\/100016834","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010037","name":"Chongqing Youth Science and Technology Talent Training Project","doi-asserted-by":"publisher","award":["CQYC20210303360"],"award-info":[{"award-number":["CQYC20210303360"]}],"id":[{"id":"10.13039\/501100010037","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002865","name":"Chongqing Municipal Science and Technology Bureau","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Insight"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.cellin.2026.100363","type":"journal-article","created":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T15:02:32Z","timestamp":1788620552000},"page":"100363","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Circadian mechanisms in heart failure: Cell-specific regulation and chrono-medicine"],"prefix":"10.1016","volume":"5","author":[{"given":"Shuting","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runchao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3650-1507","authenticated-orcid":false,"given":"Min-Dian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25021211","article-title":"Metabolic flexibility of the heart: The role of fatty acid metabolism in health, heart failure, and cardiometabolic diseases","volume":"25","author":"Actis Dato","year":"2024","journal-title":"International Journal of Molecular Sciences"},{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib2","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.immuni.2019.01.002","article-title":"A neutrophil timer coordinates immune defense and vascular protection","volume":"50","author":"Adrover","year":"2019","journal-title":"Immunity"},{"issue":"12","key":"10.1016\/j.cellin.2026.100363_bib3","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1161\/CIRCRESAHA.124.323659","article-title":"Myocardial inflammation in heart failure with reduced and preserved ejection fraction","volume":"134","author":"Alcaide","year":"2024","journal-title":"Circulation Research"},{"issue":"11","key":"10.1016\/j.cellin.2026.100363_bib4","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1161\/CIRCULATIONAHA.123.064155","article-title":"Cardiac pericytes acquire a fibrogenic phenotype and contribute to vascular maturation after myocardial infarction","volume":"148","author":"Alex","year":"2023","journal-title":"Circulation"},{"key":"10.1016\/j.cellin.2026.100363_bib5","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.54090","article-title":"Bmal1 integrates mitochondrial metabolism and macrophage activation","volume":"9","author":"Alexander","year":"2020","journal-title":"eLife"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib6","first-page":"CD013496","article-title":"Intermittent fasting for the prevention of cardiovascular disease","volume":"1","author":"Allaf","year":"2021","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"9","key":"10.1016\/j.cellin.2026.100363_bib7","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1161\/CIRCRESAHA.111.261750","article-title":"Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice","volume":"111","author":"Anea","year":"2012","journal-title":"Circulation Research"},{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib8","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20250240","article-title":"A circadian checkpoint relocates neutrophils to minimize injury","volume":"223","author":"Aroca-Crevillen","year":"2026","journal-title":"Journal of Experimental Medicine"},{"issue":"10","key":"10.1016\/j.cellin.2026.100363_bib9","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1093\/cvr\/cvad057","article-title":"The circadian protein BMAL1 supports endothelial cell cycle during angiogenesis","volume":"119","author":"Astone","year":"2023","journal-title":"Cardiovascular Research"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1161\/CIRCULATIONAHA.117.029972","article-title":"Bmal1 in perivascular adipose tissue regulates resting-phase blood pressure through transcriptional regulation of angiotensinogen","volume":"138","author":"Chang","year":"2018","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-61710-2","article-title":"Chronic circadian rhythm disorder induces heart failure with preserved ejection fraction-like phenotype through the Clock-sGC-cGMP-PKG1 signaling pathway","volume":"14","author":"Che","year":"2024","journal-title":"Scientific Reports"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib13","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1016\/j.cmet.2025.02.007","article-title":"Dietary timing enhances exercise by modulating fat-muscle crosstalk via adipocyte AMPKalpha2 signaling","volume":"37","author":"Chen","year":"2025","journal-title":"Cell Metabolism"},{"issue":"7","key":"10.1016\/j.cellin.2026.100363_bib14","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/s41569-019-0167-4","article-title":"Circadian rhythms and the molecular clock in cardiovascular biology and disease","volume":"16","author":"Crnko","year":"2019","journal-title":"Nature Reviews Cardiology"},{"key":"10.1016\/j.cellin.2026.100363_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104556","article-title":"The circadian clock remains intact, but with dampened hormonal output in heart failure","volume":"91","author":"Crnko","year":"2023","journal-title":"EBioMedicine"},{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib16","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1073\/pnas.1912109117","article-title":"The circadian clock protein REVERBalpha inhibits pulmonary fibrosis development","volume":"117","author":"Cunningham","year":"2020","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"23","key":"10.1016\/j.cellin.2026.100363_bib17","doi-asserted-by":"crossref","first-page":"7231","DOI":"10.1073\/pnas.1501327112","article-title":"Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1","volume":"112","author":"Curtis","year":"2015","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"5\u20136","key":"10.1016\/j.cellin.2026.100363_bib18","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1007\/s10495-025-02108-x","article-title":"Necroptosis in myocardial ischaemia-reperfusion injury: Current update on mechanisms, therapeutic targets, and translational potential","volume":"30","author":"Dabravolski","year":"2025","journal-title":"Apoptosis"},{"issue":"4","key":"10.1016\/j.cellin.2026.100363_bib19","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1152\/physrev.00022.2018","article-title":"Fundamental mechanisms of regulated cell death and implications for heart disease","volume":"99","author":"Del Re","year":"2019","journal-title":"Physiological Reviews"},{"issue":"4","key":"10.1016\/j.cellin.2026.100363_bib20","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.devcel.2016.10.001","article-title":"Single-cell resolution of temporal gene expression during heart development","volume":"39","author":"DeLaughter","year":"2016","journal-title":"Developmental Cell"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib21","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1161\/CIRCRESAHA.123.323513","article-title":"Circadian regulation of cardiac arrhythmias and electrophysiology","volume":"134","author":"Delisle","year":"2024","journal-title":"Circulation Research"},{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib22","doi-asserted-by":"crossref","first-page":"e257","DOI":"10.1016\/j.hrthm.2025.10.007","article-title":"BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability","volume":"23","author":"Delisle","year":"2026","journal-title":"Heart Rhythm"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib23","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/s44161-021-00001-9","article-title":"Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD(+) biosynthesis and sustain cardiac function","volume":"1","author":"Dierickx","year":"2022","journal-title":"Nature Cardiovascular Research"},{"issue":"3","key":"10.1016\/j.cellin.2026.100363_bib24","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1161\/CIRCRESAHA.109.209346","article-title":"Short communication: Ischemia\/reperfusion tolerance is time-of-day-dependent: Mediation by the cardiomyocyte circadian clock","volume":"106","author":"Durgan","year":"2010","journal-title":"Circulation Research"},{"issue":"36","key":"10.1016\/j.cellin.2026.100363_bib25","first-page":"E8460","article-title":"Circadian clock protein BMAL1 regulates IL-1beta in macrophages via NRF2","volume":"115","author":"Early","year":"2018","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib26","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1161\/CIRCRESAHA.123.323522","article-title":"Circadian influences on myocardial ischemia-reperfusion injury and heart failure","volume":"134","author":"Eckle","year":"2024","journal-title":"Circulation Research"},{"issue":"5","key":"10.1016\/j.cellin.2026.100363_bib27","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/nm.2728","article-title":"Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia","volume":"18","author":"Eckle","year":"2012","journal-title":"Nature Medicine"},{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib28","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1161\/CIRCRESAHA.122.321369","article-title":"The circadian biology of heart failure","volume":"132","author":"El Jamal","year":"2023","journal-title":"Circulation Research"},{"issue":"4","key":"10.1016\/j.cellin.2026.100363_bib29","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jacc.2020.11.044","article-title":"Etiology-dependent impairment of diastolic cardiomyocyte calcium homeostasis in heart failure with preserved ejection fraction","volume":"77","author":"Frisk","year":"2021","journal-title":"Journal of the American College of Cardiology"},{"issue":"23","key":"10.1016\/j.cellin.2026.100363_bib30","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1001\/jama.2025.4390","article-title":"Antihypertensive medication timing and cardiovascular events and death: The BedMed randomized clinical trial","volume":"333","author":"Garrison","year":"2025","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib31","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1073\/pnas.1106750109","article-title":"The nuclear receptor REV-ERBalpha mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines","volume":"109","author":"Gibbs","year":"2012","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib32","doi-asserted-by":"crossref","DOI":"10.1111\/apha.13707","article-title":"Prolonged QT intervals in mice with cardiomyocyte-specific deficiency of the molecular clock","volume":"233","author":"Gottlieb","year":"2021","journal-title":"Acta Physiol (Oxf)"},{"issue":"10","key":"10.1016\/j.cellin.2026.100363_bib33","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/j.cmet.2022.09.003","article-title":"Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight\/obesity: A randomized controlled trial","volume":"34","author":"Haganes","year":"2022","journal-title":"Cell Metabolism"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib34","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41572-024-00540-y","article-title":"Heart failure with preserved ejection fraction","volume":"10","author":"Hamo","year":"2024","journal-title":"Nature Reviews Disease Primers"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib35","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nrcardio.2016.163","article-title":"Neurohormonal activation in heart failure with reduced ejection fraction","volume":"14","author":"Hartupee","year":"2017","journal-title":"Nature Reviews Cardiology"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib36","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1038\/s41467-021-22788-8","article-title":"Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia","volume":"12","author":"Hayter","year":"2021","journal-title":"Nature Communications"},{"issue":"4","key":"10.1016\/j.cellin.2026.100363_bib37","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.cmet.2016.03.007","article-title":"The small molecule nobiletin targets the molecular oscillator to enhance circadian rhythms and protect against metabolic syndrome","volume":"23","author":"He","year":"2016","journal-title":"Cell Metabolism"},{"issue":"18","key":"10.1016\/j.cellin.2026.100363_bib38","first-page":"e895","article-title":"2022 AHA\/ACC\/HFSA guideline for the management of heart failure: A report of the American college of cardiology\/american heart association joint committee on clinical practice guidelines","volume":"145","author":"Heidenreich","year":"2022","journal-title":"Circulation"},{"issue":"6617","key":"10.1016\/j.cellin.2026.100363_bib39","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1126\/science.abl8007","article-title":"Time-restricted feeding mitigates obesity through adipocyte thermogenesis","volume":"378","author":"Hepler","year":"2022","journal-title":"Science"},{"issue":"48","key":"10.1016\/j.cellin.2026.100363_bib40","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1093\/eurheartj\/ehz754","article-title":"Bedtime hypertension treatment improves cardiovascular risk reduction: The hygia chronotherapy trial","volume":"41","author":"Hermida","year":"2020","journal-title":"European Heart Journal"},{"issue":"9932","key":"10.1016\/j.cellin.2026.100363_bib41","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1016\/S0140-6736(14)60107-0","article-title":"Cardiovascular remodelling in coronary artery disease and heart failure","volume":"383","author":"Heusch","year":"2014","journal-title":"Lancet"},{"issue":"415","key":"10.1016\/j.cellin.2026.100363_bib42","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aal2774","article-title":"Circadian actin dynamics drive rhythmic fibroblast mobilization during wound healing","volume":"9","author":"Hoyle","year":"2017","journal-title":"Science Translational Medicine"},{"key":"10.1016\/j.cellin.2026.100363_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.659973","article-title":"Telemonitored human circadian temperature dynamics during daily routine","volume":"12","author":"Huang","year":"2021","journal-title":"Frontiers in Physiology"},{"issue":"12","key":"10.1016\/j.cellin.2026.100363_bib44","doi-asserted-by":"crossref","DOI":"10.1242\/dev.173047","article-title":"Maturation of heart valve cell populations during postnatal remodeling","volume":"146","author":"Hulin","year":"2019","journal-title":"Development"},{"key":"10.1016\/j.cellin.2026.100363_bib45","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.63324","article-title":"Adipocyte NR1D1 dictates adipose tissue expansion during obesity","volume":"10","author":"Hunter","year":"2021","journal-title":"eLife"},{"issue":"11","key":"10.1016\/j.cellin.2026.100363_bib46","doi-asserted-by":"crossref","first-page":"H1827","DOI":"10.1152\/ajpheart.00608.2015","article-title":"Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation","volume":"309","author":"Ingle","year":"2015","journal-title":"American Journal of Physiology - Heart and Circulatory Physiology"},{"issue":"9","key":"10.1016\/j.cellin.2026.100363_bib47","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1001\/jamainternmed.2022.3050","article-title":"Effectiveness of early time-restricted eating for weight loss, fat loss, and cardiometabolic health in adults with obesity: A randomized clinical trial","volume":"182","author":"Jamshed","year":"2022","journal-title":"JAMA Internal Medicine"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib48","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/s41467-018-03105-2","article-title":"Hypoxia-inducible factor 2-alpha-dependent induction of amphiregulin dampens myocardial ischemia-reperfusion injury","volume":"9","author":"Koeppen","year":"2018","journal-title":"Nature Communications"},{"issue":"6530","key":"10.1016\/j.cellin.2026.100363_bib49","doi-asserted-by":"crossref","DOI":"10.1126\/science.abd0951","article-title":"Communicating clocks shape circadian homeostasis","volume":"371","author":"Koronowski","year":"2021","journal-title":"Science"},{"issue":"12","key":"10.1016\/j.cellin.2026.100363_bib50","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1056\/NEJMoa2306963","article-title":"Semaglutide in patients with heart failure with preserved ejection fraction and obesity","volume":"389","author":"Kosiborod","year":"2023","journal-title":"New England Journal of Medicine"},{"issue":"4","key":"10.1016\/j.cellin.2026.100363_bib51","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.cmet.2016.02.007","article-title":"Brown adipose tissue exhibits a glucose-responsive thermogenic biorhythm in humans","volume":"23","author":"Lee","year":"2016","journal-title":"Cell Metabolism"},{"issue":"4","key":"10.1016\/j.cellin.2026.100363_bib52","doi-asserted-by":"crossref","first-page":"H475","DOI":"10.1152\/ajpheart.00238.2012","article-title":"Development of dilated cardiomyopathy in Bmal1-deficient mice","volume":"303","author":"Lefta","year":"2012","journal-title":"American Journal of Physiology - Heart and Circulatory Physiology"},{"issue":"9","key":"10.1016\/j.cellin.2026.100363_bib54","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s13238-020-00713-x","article-title":"BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy","volume":"11","author":"Li","year":"2020","journal-title":"Protein & Cell"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib53","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.molmed.2021.10.006","article-title":"Clock-modulated checkpoints in time-restricted eating","volume":"28","author":"Li","year":"2022","journal-title":"Trends in Molecular Medicine"},{"issue":"5","key":"10.1016\/j.cellin.2026.100363_bib55","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1161\/ATVBAHA.121.316480","article-title":"Clock gene Bmal1 disruption in vascular smooth muscle cells worsens carotid atherosclerotic lesions","volume":"42","author":"Lin","year":"2022","journal-title":"Arteriosclerosis, Thrombosis, and Vascular Biology"},{"issue":"7838","key":"10.1016\/j.cellin.2026.100363_bib56","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/s41586-020-2797-4","article-title":"Cells of the adult human heart","volume":"588","author":"Litvinukova","year":"2020","journal-title":"Nature"},{"issue":"16","key":"10.1016\/j.cellin.2026.100363_bib57","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1056\/NEJMoa2114833","article-title":"Calorie restriction with or without time-restricted eating in weight loss","volume":"386","author":"Liu","year":"2022","journal-title":"New England Journal of Medicine"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib58","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.cmet.2016.06.001","article-title":"Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan","volume":"23","author":"Longo","year":"2016","journal-title":"Cell Metabolism"},{"issue":"8","key":"10.1016\/j.cellin.2026.100363_bib59","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.125.048092","article-title":"Effect of 2 weeks of time-restricted eating on innate immunity and systemic inflammation in patients with a history of myocardial infarction: A randomized-controlled crossover study","volume":"15","author":"Los","year":"2026","journal-title":"Journal of American Heart Association"},{"issue":"11","key":"10.1016\/j.cellin.2026.100363_bib60","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1001\/jamainternmed.2020.4153","article-title":"Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: The TREAT randomized clinical trial","volume":"180","author":"Lowe","year":"2020","journal-title":"JAMA Internal Medicine"},{"key":"10.1016\/j.cellin.2026.100363_bib61","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.899628","article-title":"REV-ERB is essential in cardiac fibroblasts homeostasis","volume":"13","author":"Luo","year":"2022","journal-title":"Frontiers in Pharmacology"},{"issue":"10361","key":"10.1016\/j.cellin.2026.100363_bib62","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/S0140-6736(22)01786-X","article-title":"Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): A prospective, randomised, open-label, blinded-endpoint clinical trial","volume":"400","author":"Mackenzie","year":"2022","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib63","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/s42255-021-00395-7","article-title":"The liver-clock coordinates rhythmicity of peripheral tissues in response to feeding","volume":"3","author":"Manella","year":"2021","journal-title":"Nature Metabolism"},{"issue":"3","key":"10.1016\/j.cellin.2026.100363_bib64","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1177\/0748730415575246","article-title":"Influence of the cardiomyocyte circadian clock on cardiac physiology and pathophysiology","volume":"30","author":"Martino","year":"2015","journal-title":"Journal of Biological Rhythms"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib65","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1038\/s41467-021-22571-9","article-title":"Circadian clock dysfunction in human omental fat links obesity to metabolic inflammation","volume":"12","author":"Maury","year":"2021","journal-title":"Nature Communications"},{"issue":"36","key":"10.1016\/j.cellin.2026.100363_bib120","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"European Heart Journal"},{"issue":"7","key":"10.1016\/j.cellin.2026.100363_bib66","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1093\/cvr\/cvab205","article-title":"Loss of Yap\/Taz in cardiac fibroblasts attenuates adverse remodelling and improves cardiac function","volume":"118","author":"Mia","year":"2022","journal-title":"Cardiovascular Research"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib67","doi-asserted-by":"crossref","first-page":"H1487","DOI":"10.1152\/ajpheart.00709.2019","article-title":"Differential effects of REV-ERBalpha\/beta agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption","volume":"318","author":"Mia","year":"2020","journal-title":"American Journal of Physiology - Heart and Circulatory Physiology"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib68","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1146\/annurev-neuro-060909-153128","article-title":"Central and peripheral circadian clocks in mammals","volume":"35","author":"Mohawk","year":"2012","journal-title":"Annual Review of Neuroscience"},{"issue":"10115","key":"10.1016\/j.cellin.2026.100363_bib69","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0140-6736(17)32132-3","article-title":"Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by rev-erbalpha antagonism: A single-centre propensity-matched cohort study and a randomised study","volume":"391","author":"Montaigne","year":"2018","journal-title":"Lancet"},{"issue":"6381","key":"10.1016\/j.cellin.2026.100363_bib70","doi-asserted-by":"crossref","DOI":"10.1126\/science.aao0318","article-title":"Diurnal transcriptome atlas of a primate across major neural and peripheral tissues","volume":"359","author":"Mure","year":"2018","journal-title":"Science"},{"issue":"6153","key":"10.1016\/j.cellin.2026.100363_bib71","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1126\/science.1240636","article-title":"Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes","volume":"341","author":"Nguyen","year":"2013","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib72","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.celrep.2019.07.020","article-title":"Intense light-mediated circadian cardioprotection via transcriptional reprogramming of the endothelium","volume":"28","author":"Oyama","year":"2019","journal-title":"Cell Reports"},{"issue":"20","key":"10.1016\/j.cellin.2026.100363_bib73","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1016\/j.jacc.2018.03.509","article-title":"Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium","volume":"71","author":"Packer","year":"2018","journal-title":"Journal of the American College of Cardiology"},{"issue":"12","key":"10.1016\/j.cellin.2026.100363_bib74","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1038\/nm.2979","article-title":"Obesity in mice with adipocyte-specific deletion of clock component Arntl","volume":"18","author":"Paschos","year":"2012","journal-title":"Nature Medicine"},{"issue":"6158","key":"10.1016\/j.cellin.2026.100363_bib75","doi-asserted-by":"crossref","DOI":"10.1126\/science.1243417","article-title":"Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice","volume":"342","author":"Peek","year":"2013","journal-title":"Science"},{"issue":"822","key":"10.1016\/j.cellin.2026.100363_bib76","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adv6787","article-title":"Intended isocaloric time-restricted eating shifts circadian clocks but does not improve cardiometabolic health in women with overweight","volume":"17","author":"Peters","year":"2025","journal-title":"Science Translational Medicine"},{"issue":"7","key":"10.1016\/j.cellin.2026.100363_bib77","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1161\/CIRCULATIONAHA.118.036550","article-title":"Circadian-regulated cell death in cardiovascular diseases","volume":"139","author":"Rabinovich-Nikitin","year":"2019","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib78","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s40364-025-00728-8","article-title":"Global, regional, and national burden of heart failure and its underlying causes, 1990-2021: Results from the global burden of disease study 2021","volume":"13","author":"Ran","year":"2025","journal-title":"Biomarker research"},{"issue":"8064","key":"10.1016\/j.cellin.2026.100363_bib79","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/s41586-025-08898-z","article-title":"BMAL1-HIF2A heterodimer modulates circadian variations of myocardial injury","volume":"641","author":"Ruan","year":"2025","journal-title":"Nature"},{"issue":"17","key":"10.1016\/j.cellin.2026.100363_bib80","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1161\/CIRCULATIONAHA.105.568626","article-title":"Bioinformatic analysis of circadian gene oscillation in mouse aorta","volume":"112","author":"Rudic","year":"2005","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib81","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1161\/CIRCULATIONAHA.112.135608","article-title":"Pivotal role of rho-associated kinase 2 in generating the intrinsic circadian rhythm of vascular contractility","volume":"127","author":"Saito","year":"2013","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib82","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s00418-017-1597-x","article-title":"Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF-alpha","volume":"148","author":"Sato","year":"2017","journal-title":"Histochemistry and Cell Biology"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib83","doi-asserted-by":"crossref","first-page":"407","DOI":"10.4049\/jimmunol.1301982","article-title":"A circadian clock gene, Rev-erbalpha, modulates the inflammatory function of macrophages through the negative regulation of Ccl2 expression","volume":"192","author":"Sato","year":"2014","journal-title":"Journal of Immunology"},{"issue":"7","key":"10.1016\/j.cellin.2026.100363_bib84","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/s41577-018-0008-4","article-title":"Clocking in to immunity","volume":"18","author":"Scheiermann","year":"2018","journal-title":"Nature Reviews Immunology"},{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib85","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.immuni.2012.05.021","article-title":"Adrenergic nerves govern circadian leukocyte recruitment to tissues","volume":"37","author":"Scheiermann","year":"2012","journal-title":"Immunity"},{"issue":"8","key":"10.1016\/j.cellin.2026.100363_bib86","doi-asserted-by":"crossref","first-page":"937","DOI":"10.15252\/emmm.201506083","article-title":"The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment","volume":"8","author":"Schloss","year":"2016","journal-title":"EMBO Molecular Medicine"},{"issue":"3","key":"10.1016\/j.cellin.2026.100363_bib87","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.cmet.2018.01.011","article-title":"Circadian control of DRP1 activity regulates mitochondrial dynamics and bioenergetics","volume":"27","author":"Schmitt","year":"2018","journal-title":"Cell Metabolism"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib88","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.hrthm.2015.02.019","article-title":"The cardiomyocyte molecular clock regulates the circadian expression of Kcnh2 and contributes to ventricular repolarization","volume":"12","author":"Schroder","year":"2015","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.cellin.2026.100363_bib89","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.681011","article-title":"Cardiomyocyte deletion of Bmal1 exacerbates QT- and RR-Interval prolongation in Scn5a (+\/DeltaKPQ) mice","volume":"12","author":"Schroder","year":"2021","journal-title":"Frontiers in Physiology"},{"issue":"24","key":"10.1016\/j.cellin.2026.100363_bib90","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1093\/eurheartj\/ehac109","article-title":"Circadian nuclear receptor Rev-erb\u03b1 is expressed by platelets and potentiates platelet activation and thrombus formation","volume":"43","author":"Shi","year":"2022","journal-title":"European Heart Journal"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib91","doi-asserted-by":"crossref","DOI":"10.1093\/ehjopen\/oead129","article-title":"Pericyte loss initiates microvascular dysfunction in the development of diastolic dysfunction","volume":"4","author":"Simmonds","year":"2024","journal-title":"European Heart Journal Open"},{"issue":"3","key":"10.1016\/j.cellin.2026.100363_bib92","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.celrep.2017.12.072","article-title":"Single-cell transcriptional profiling reveals cellular diversity and intercommunication in the mouse heart","volume":"22","author":"Skelly","year":"2018","journal-title":"Cell Reports"},{"issue":"12","key":"10.1016\/j.cellin.2026.100363_bib93","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1056\/NEJMoa2206286","article-title":"Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction","volume":"387","author":"Solomon","year":"2022","journal-title":"New England Journal of Medicine"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib95","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1161\/CIRCULATIONAHA.121.056076","article-title":"Myocardial rev-erb-mediated diurnal metabolic rhythm and obesity paradox","volume":"145","author":"Song","year":"2022","journal-title":"Circulation"},{"issue":"22","key":"10.1016\/j.cellin.2026.100363_bib96","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.026708","article-title":"Persistent high burden of heart failure across the ejection fraction spectrum in a nationwide setting","volume":"11","author":"Stolfo","year":"2022","journal-title":"Journal of American Heart Association"},{"issue":"7817","key":"10.1016\/j.cellin.2026.100363_bib97","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1038\/s41586-020-2496-1","article-title":"A single-cell transcriptomic atlas characterizes ageing tissues in the mouse","volume":"583","author":"Tabula Muris","year":"2020","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.cellin.2026.100363_bib98","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/nrg.2016.150","article-title":"Transcriptional architecture of the mammalian circadian clock","volume":"18","author":"Takahashi","year":"2017","journal-title":"Nature Reviews Genetics"},{"issue":"48","key":"10.1016\/j.cellin.2026.100363_bib99","article-title":"Cardiac urea cycle activation by time-restricted feeding protects against pressure overload-induced heart failure","volume":"11","author":"Tan","year":"2024","journal-title":"Advanced Science (Weinheim)"},{"issue":"10","key":"10.1016\/j.cellin.2026.100363_bib100","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1161\/CIRCRESAHA.123.323464","article-title":"Cardiac GR mediates the diurnal rhythm in ventricular arrhythmia susceptibility","volume":"134","author":"Tikhomirov","year":"2024","journal-title":"Circulation Research"},{"issue":"16","key":"10.1016\/j.cellin.2026.100363_bib101","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.121.020896","article-title":"Adverse effect of circadian rhythm disorder on reparative angiogenesis in hind limb Ischemia","volume":"10","author":"Tsuzuki","year":"2021","journal-title":"Journal of American Heart Association"},{"issue":"7","key":"10.1016\/j.cellin.2026.100363_bib102","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1161\/CIRCULATIONAHA.111.076075","article-title":"Low myocardial protein kinase G activity in heart failure with preserved ejection fraction","volume":"126","author":"van Heerebeek","year":"2012","journal-title":"Circulation"},{"issue":"16","key":"10.1016\/j.cellin.2026.100363_bib103","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1161\/CIRCULATIONAHA.106.653303","article-title":"Mutation of the circadian clock gene Per2 alters vascular endothelial function","volume":"115","author":"Viswambharan","year":"2007","journal-title":"Circulation"},{"issue":"72","key":"10.1016\/j.cellin.2026.100363_bib105","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abm2465","article-title":"The circadian immune system","volume":"7","author":"Wang","year":"2022","journal-title":"Science Immunology"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib106","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1186\/s12967-025-06828-1","article-title":"Role of circadian rhythms in heart failure: Insights from myocardial energy metabolism","volume":"23","author":"Wang","year":"2025","journal-title":"Journal of Translational Medicine"},{"key":"10.1016\/j.cellin.2026.100363_bib104","article-title":"Sympathetic nervous system mediates cardiac remodeling after myocardial infarction in a circadian disruption model","volume":"8","author":"Wang","year":"2021","journal-title":"Frontiers in Cardiovascular Medicine"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib107","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1146\/annurev-physiol-021909-135919","article-title":"Suprachiasmatic nucleus: Cell autonomy and network properties","volume":"72","author":"Welsh","year":"2010","journal-title":"Annual Review of Physiology"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib108","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.cmet.2019.11.004","article-title":"Ten-hour time-restricted eating reduces weight, blood pressure, and atherogenic lipids in patients with metabolic syndrome","volume":"31","author":"Wilkinson","year":"2020","journal-title":"Cell Metabolism"},{"issue":"2","key":"10.1016\/j.cellin.2026.100363_bib109","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.cmet.2024.01.007","article-title":"Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding","volume":"36","author":"Williams","year":"2024","journal-title":"Cell Metabolism"},{"issue":"6","key":"10.1016\/j.cellin.2026.100363_bib111","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1161\/CIRCRESAHA.119.315502","article-title":"BMAL1-Downregulation aggravates porphyromonas gingivalis-induced atherosclerosis by encouraging oxidative stress","volume":"126","author":"Xie","year":"2020","journal-title":"Circulation Research"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib110","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1172\/JCI76881","article-title":"Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation","volume":"125","author":"Xie","year":"2015","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.cellin.2026.100363_bib112","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2020.111110","article-title":"Chronic circadian shift leads to adipose tissue inflammation and fibrosis","volume":"521","author":"Xiong","year":"2021","journal-title":"Molecular and Cellular Endocrinology"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib113","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/s41392-025-02253-4","article-title":"Mitochondria in oxidative stress, inflammation and aging: From mechanisms to therapeutic advances","volume":"10","author":"Xu","year":"2025","journal-title":"Signal Transduction and Targeted Therapy"},{"issue":"9","key":"10.1016\/j.cellin.2026.100363_bib114","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20211098","article-title":"Macrophage-adipocyte communication and cardiac remodeling","volume":"218","author":"Yepuri","year":"2021","journal-title":"Journal of Experimental Medicine"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib115","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1038\/s41467-021-23050-x","article-title":"Alteration of circadian machinery in monocytes underlies chronic kidney disease-associated cardiac inflammation and fibrosis","volume":"12","author":"Yoshida","year":"2021","journal-title":"Nature Communications"},{"issue":"1","key":"10.1016\/j.cellin.2026.100363_bib116","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1146\/annurev-physiol-020518-114349","article-title":"Circadian regulation of cardiac physiology: Rhythms that keep the heart beating","volume":"82","author":"Zhang","year":"2020","journal-title":"Annual Review of Physiology"},{"issue":"15","key":"10.1016\/j.cellin.2026.100363_bib117","doi-asserted-by":"crossref","DOI":"10.1172\/JCI148276","article-title":"Circadian regulation of cardiac metabolism","volume":"131","author":"Zhang","year":"2021","journal-title":"Journal of Clinical Investigation"},{"issue":"17","key":"10.1016\/j.cellin.2026.100363_bib118","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.95177","article-title":"REV-ERBalpha ameliorates heart failure through transcription repression","volume":"2","author":"Zhang","year":"2017","journal-title":"JCI Insight"},{"issue":"10","key":"10.1016\/j.cellin.2026.100363_bib119","first-page":"3150","article-title":"BMAL1 suppresses ROS-induced endothelial-to-mesenchymal transition and atherosclerosis plaque progression via BMP signaling","volume":"10","author":"Zhu","year":"2018","journal-title":"American Journal of Translational Research"}],"container-title":["Cell Insight"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772892726000660?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772892726000660?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:48:15Z","timestamp":1791499695000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772892726000660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":118,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["S2772892726000660"],"URL":"https:\/\/doi.org\/10.1016\/j.cellin.2026.100363","relation":{},"ISSN":["2772-8927"],"issn-type":[{"value":"2772-8927","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Circadian mechanisms in heart failure: Cell-specific regulation and chrono-medicine","name":"articletitle","label":"Article Title"},{"value":"Cell Insight","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellin.2026.100363","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V. on behalf of Wuhan University.","name":"copyright","label":"Copyright"}],"article-number":"100363"}}