{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:26:17Z","timestamp":1791048377670,"version":"4.1.0"},"reference-count":94,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.cellsig.2006.09.005","type":"journal-article","created":{"date-parts":[[2006,11,4]],"date-time":"2006-11-04T07:14:20Z","timestamp":1162624460000},"page":"444-453","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"title":["Cell biology of polycystin-2"],"prefix":"10.1016","volume":"19","author":[{"given":"Leonidas","family":"Tsiokas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sehyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E-Ching","family":"Ong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5266","key":"10.1016\/j.cellsig.2006.09.005_bib1","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1126\/science.272.5266.1339","volume":"272","author":"Mochizuki","year":"1996","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.cellsig.2006.09.005_bib2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/ng0695-151","volume":"10","author":"Hughes","year":"1995","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.cellsig.2006.09.005_bib3","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/0092-8674(94)90137-6","volume":"77","author":"Consortium EPKD","year":"1994","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.cellsig.2006.09.005_bib4","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0092-8674(95)90339-9","volume":"81","author":"Consortium IPKD","year":"1995","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib5","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1056\/NEJM199307293290508","volume":"329","author":"Gabow","year":"1993","journal-title":"N. Engl. J. Med."},{"issue":"6","key":"10.1016\/j.cellsig.2006.09.005_bib6","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/S0272-6386(96)90378-9","volume":"28","author":"Grantham","year":"1996","journal-title":"Am. J. Kidney Dis."},{"issue":"2","key":"10.1016\/j.cellsig.2006.09.005_bib7","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1056\/NEJMra022161","volume":"350","author":"Wilson","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cellsig.2006.09.005_bib8","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1146\/annurev.med.52.1.93","volume":"52","author":"Arnaout","year":"2001","journal-title":"Annu. Rev. Med."},{"issue":"9","key":"10.1016\/j.cellsig.2006.09.005_bib9","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/S0962-8924(03)00169-7","volume":"13","author":"Boletta","year":"2003","journal-title":"Trends Cell Biol."},{"issue":"9","key":"10.1016\/j.cellsig.2006.09.005_bib10","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1097\/01.ASN.0000028643.17901.42","volume":"13","author":"Igarashi","year":"2002","journal-title":"J. Am. Soc. Nephrol."},{"issue":"7","key":"10.1016\/j.cellsig.2006.09.005_bib11","doi-asserted-by":"crossref","first-page":"3934","DOI":"10.1073\/pnas.96.7.3934","volume":"96","author":"Tsiokas","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib12","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0092-8674(02)00670-0","volume":"108","author":"Montell","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.cellsig.2006.09.005_bib13","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1146\/annurev.physiol.68.040204.100431","volume":"68","author":"Ramsey","year":"2006","journal-title":"Annu. Rev. Physiol."},{"issue":"6966","key":"10.1016\/j.cellsig.2006.09.005_bib14","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nature02196","volume":"426","author":"Clapham","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.cellsig.2006.09.005_bib15","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1146\/annurev.physiol.68.040204.101406","volume":"68","author":"Owsianik","year":"2006","journal-title":"Annu. Rev. Physiol."},{"issue":"Pt 2","key":"10.1016\/j.cellsig.2006.09.005_bib16","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1042\/bj20021381","volume":"371","author":"Turner","year":"2003","journal-title":"Biochem. J."},{"issue":"3","key":"10.1016\/j.cellsig.2006.09.005_bib17","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1600-0854.2006.00387.x","volume":"7","author":"Vergarajauregui","year":"2006","journal-title":"Traffic"},{"issue":"25","key":"10.1016\/j.cellsig.2006.09.005_bib18","doi-asserted-by":"crossref","first-page":"17517","DOI":"10.1074\/jbc.M600807200","volume":"281","author":"Venkatachalam","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"18","key":"10.1016\/j.cellsig.2006.09.005_bib19","doi-asserted-by":"crossref","first-page":"12751","DOI":"10.1074\/jbc.M511104200","volume":"281","author":"Miedel","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.cellsig.2006.09.005_bib20","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1002\/mrd.20312","volume":"71","author":"Teilmann","year":"2005","journal-title":"Mol. Reprod. Dev."},{"issue":"35","key":"10.1016\/j.cellsig.2006.09.005_bib21","doi-asserted-by":"crossref","first-page":"12572","DOI":"10.1073\/pnas.0502403102","volume":"102","author":"Shin","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"41","key":"10.1016\/j.cellsig.2006.09.005_bib22","doi-asserted-by":"crossref","first-page":"34718","DOI":"10.1074\/jbc.M507793200","volume":"280","author":"Raychowdhury","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.cellsig.2006.09.005_bib23","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/hmg\/11.1.59","volume":"11","author":"Scheffers","year":"2002","journal-title":"Hum. Mol. Genet."},{"issue":"7","key":"10.1016\/j.cellsig.2006.09.005_bib24","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1128\/MCB.23.7.2600-2607.2003","volume":"23","author":"Luo","year":"2003","journal-title":"Mol. Cell. Biol."},{"issue":"40","key":"10.1016\/j.cellsig.2006.09.005_bib25","doi-asserted-by":"crossref","first-page":"28557","DOI":"10.1074\/jbc.274.40.28557","volume":"274","author":"Cai","year":"1999","journal-title":"J. Biol. Chem."},{"issue":"11","key":"10.1016\/j.cellsig.2006.09.005_bib26","doi-asserted-by":"crossref","first-page":"R378","DOI":"10.1016\/S0960-9822(02)00877-1","volume":"12","author":"Pazour","year":"2002","journal-title":"Curr. Biol."},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib27","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1083\/jcb.200405023","volume":"166","author":"Jurczyk","year":"2004","journal-title":"J. Cell Biol."},{"issue":"28","key":"10.1016\/j.cellsig.2006.09.005_bib28","doi-asserted-by":"crossref","first-page":"29728","DOI":"10.1074\/jbc.M400544200","volume":"279","author":"Rundle","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"6815","key":"10.1016\/j.cellsig.2006.09.005_bib29","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1038\/35050128","volume":"408","author":"Hanaoka","year":"2000","journal-title":"Nature"},{"issue":"6751","key":"10.1016\/j.cellsig.2006.09.005_bib30","first-page":"383","volume":"401","author":"Chen","year":"1999","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.cellsig.2006.09.005_bib31","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1073\/pnas.98.3.1182","volume":"98","author":"Gonzalez-Perrett","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.cellsig.2006.09.005_bib32","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1006\/bbrc.2001.4554","volume":"282","author":"Vassilev","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"2","key":"10.1016\/j.cellsig.2006.09.005_bib33","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1681\/ASN.2004121146","volume":"17","author":"Pelucchi","year":"2006","journal-title":"J. Am. Soc. Nephrol."},{"issue":"6","key":"10.1016\/j.cellsig.2006.09.005_bib34","doi-asserted-by":"crossref","first-page":"F1012","DOI":"10.1152\/ajprenal.00181.2003","volume":"286","author":"Cantiello","year":"2004","journal-title":"Am. J. Physiol., Renal Fluid Electrolyte Physiol."},{"issue":"6","key":"10.1016\/j.cellsig.2006.09.005_bib35","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1096\/fj.03-0319fje","volume":"18","author":"Delmas","year":"2004","journal-title":"FASEB J."},{"issue":"18","key":"10.1016\/j.cellsig.2006.09.005_bib36","doi-asserted-by":"crossref","first-page":"8285","DOI":"10.1128\/MCB.25.18.8285-8298.2005","volume":"25","author":"Ma","year":"2005","journal-title":"Mol. Cell. Biol."},{"issue":"33","key":"10.1016\/j.cellsig.2006.09.005_bib37","doi-asserted-by":"crossref","first-page":"35009","DOI":"10.1074\/jbc.M314206200","volume":"279","author":"Hidaka","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.cellsig.2006.09.005_bib38","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/sj.emboj.7600566","volume":"24","author":"Kottgen","year":"2005","journal-title":"EMBO J."},{"issue":"9","key":"10.1016\/j.cellsig.2006.09.005_bib39","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1093\/hmg\/ddl070","volume":"15","author":"Streets","year":"2006","journal-title":"Hum. Mol. Genet."},{"issue":"23","key":"10.1016\/j.cellsig.2006.09.005_bib40","doi-asserted-by":"crossref","first-page":"20763","DOI":"10.1074\/jbc.M107788200","volume":"277","author":"Newby","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"13","key":"10.1016\/j.cellsig.2006.09.005_bib41","doi-asserted-by":"crossref","first-page":"6965","DOI":"10.1073\/pnas.94.13.6965","volume":"94","author":"Tsiokas","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.cellsig.2006.09.005_bib42","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/ng0697-179","volume":"16","author":"Qian","year":"1997","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.cellsig.2006.09.005_bib43","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1007\/s00424-005-1417-3","volume":"451","author":"Kottgen","year":"2005","journal-title":"Pflugers Arch."},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib44","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1006\/bbrc.2001.4720","volume":"282","author":"Chen","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.cellsig.2006.09.005_bib45","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/ncb754","volume":"4","author":"Koulen","year":"2002","journal-title":"Nat. Cell Biol."},{"issue":"50","key":"10.1016\/j.cellsig.2006.09.005_bib46","doi-asserted-by":"crossref","first-page":"41298","DOI":"10.1074\/jbc.M510082200","volume":"280","author":"Li","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"15","key":"10.1016\/j.cellsig.2006.09.005_bib47","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1093\/hmg\/ddg190","volume":"12","author":"Qian","year":"2003","journal-title":"Hum. Mol. Genet."},{"issue":"7","key":"10.1016\/j.cellsig.2006.09.005_bib48","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1096\/fj.03-0687fje","volume":"18","author":"Aguiari","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.cellsig.2006.09.005_bib49","first-page":"101","volume":"234","author":"Hagiwara","year":"2004","journal-title":"Int. Rev. Cyt."},{"key":"10.1016\/j.cellsig.2006.09.005_bib50","first-page":"225","volume":"19","author":"Zhang","year":"2004","journal-title":"Physiology (Bethesda)"},{"issue":"6","key":"10.1016\/j.cellsig.2006.09.005_bib51","doi-asserted-by":"crossref","first-page":"F1159","DOI":"10.1152\/ajprenal.00118.2005","volume":"289","author":"Davenport","year":"2005","journal-title":"Am. J. Physiol., Renal Fluid Electrolyte Physiol."},{"issue":"6","key":"10.1016\/j.cellsig.2006.09.005_bib52","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.cell.2004.05.019","volume":"117","author":"Snell","year":"2004","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.cellsig.2006.09.005_bib53","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0955-0674(02)00012-1","volume":"15","author":"Pazour","year":"2003","journal-title":"Curr. Opin. Cell Biol."},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib54","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/00041552-200309000-00006","volume":"12","author":"Praetorius","year":"2003","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"1","key":"10.1016\/j.cellsig.2006.09.005_bib55","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00232-001-0075-4","volume":"184","author":"Praetorius","year":"2001","journal-title":"J. Membr. Biol."},{"issue":"1","key":"10.1016\/j.cellsig.2006.09.005_bib56","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00232-002-1042-4","volume":"191","author":"Praetorius","year":"2003","journal-title":"J. Membr. Biol."},{"issue":"3","key":"10.1016\/j.cellsig.2006.09.005_bib57","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00232-002-1055-z","volume":"191","author":"Praetorius","year":"2003","journal-title":"J. Membr. Biol."},{"issue":"10","key":"10.1016\/j.cellsig.2006.09.005_bib58","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1097\/01.ASN.0000029587.47950.25","volume":"13","author":"Yoder","year":"2002","journal-title":"J. Am. Soc. Nephrol."},{"issue":"Pt 7","key":"10.1016\/j.cellsig.2006.09.005_bib59","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1242\/jcs.02818","volume":"119","author":"Geng","year":"2006","journal-title":"J. Cell Sci."},{"issue":"8","key":"10.1016\/j.cellsig.2006.09.005_bib60","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1432-0436.2005.00048.x","volume":"73","author":"Karcher","year":"2005","journal-title":"Differentiation"},{"issue":"1","key":"10.1016\/j.cellsig.2006.09.005_bib61","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0092-8674(03)00511-7","volume":"114","author":"McGrath","year":"2003","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.cellsig.2006.09.005_bib62","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/ng1076","volume":"33","author":"Nauli","year":"2003","journal-title":"Nat. Genet."},{"issue":"18","key":"10.1016\/j.cellsig.2006.09.005_bib63","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/j.cub.2005.08.047","volume":"15","author":"Qin","year":"2005","journal-title":"Curr. Biol."},{"issue":"2","key":"10.1016\/j.cellsig.2006.09.005_bib64","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0092-8674(95)90408-5","volume":"80","author":"Clapham","year":"1995","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.cellsig.2006.09.005_bib65","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1083\/jcb.200504008","volume":"170","author":"Pazour","year":"2005","journal-title":"J. Cell Biol."},{"issue":"6962","key":"10.1016\/j.cellsig.2006.09.005_bib66","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/nature02061","volume":"426","author":"Huangfu","year":"2003","journal-title":"Nature"},{"issue":"7061","key":"10.1016\/j.cellsig.2006.09.005_bib67","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1038\/nature04117","volume":"437","author":"Corbit","year":"2005","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.cellsig.2006.09.005_bib68","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1371\/journal.pgen.0010053","volume":"1","author":"Haycraft","year":"2005","journal-title":"PLoS Genet."},{"issue":"20","key":"10.1016\/j.cellsig.2006.09.005_bib69","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1016\/j.cub.2005.09.012","volume":"15","author":"Schneider","year":"2005","journal-title":"Curr. Biol."},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib70","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1083\/jcb.200402130","volume":"165","author":"Martinez-Campos","year":"2004","journal-title":"J. Cell Biol."},{"issue":"7","key":"10.1016\/j.cellsig.2006.09.005_bib71","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.cell.2006.05.025","volume":"125","author":"Basto","year":"2006","journal-title":"Cell"},{"issue":"5221","key":"10.1016\/j.cellsig.2006.09.005_bib72","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1126\/science.7618084","volume":"269","author":"Threadgill","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.cellsig.2006.09.005_bib73","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0092-8674(00)81570-6","volume":"93","author":"Wu","year":"1998","journal-title":"Cell"},{"issue":"8","key":"10.1016\/j.cellsig.2006.09.005_bib74","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/ncb1150","volume":"6","author":"Bezzerides","year":"2004","journal-title":"Nat. Cell Biol."},{"issue":"38","key":"10.1016\/j.cellsig.2006.09.005_bib75","doi-asserted-by":"crossref","first-page":"36786","DOI":"10.1074\/jbc.M306536200","volume":"278","author":"Grimm","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.cellsig.2006.09.005_bib76","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.molcel.2006.04.015","volume":"22","author":"Nilius","year":"2006","journal-title":"Mol. Cells"},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib77","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/ncb1251","volume":"7","author":"Ishikawa","year":"2005","journal-title":"Nat. Cell Biol."},{"issue":"11","key":"10.1016\/j.cellsig.2006.09.005_bib78","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1681\/ASN.V10112342","volume":"10","author":"Reynolds","year":"1999","journal-title":"J. Am. Soc. Nephrol."},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib79","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0272-6386(97)90496-0","volume":"30","author":"Yamaguchi","year":"1997","journal-title":"Am. J. Kidney Dis."},{"issue":"15","key":"10.1016\/j.cellsig.2006.09.005_bib80","doi-asserted-by":"crossref","first-page":"6007","DOI":"10.1073\/pnas.86.15.6007","volume":"86","author":"Mangoo-Karim","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.cellsig.2006.09.005_bib81","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1046\/j.1523-1755.2000.00991.x","volume":"57","author":"Yamaguchi","year":"2000","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.cellsig.2006.09.005_bib82","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1152\/physrev.1998.78.4.1165","volume":"78","author":"Sullivan","year":"1998","journal-title":"Physiol. Rev."},{"issue":"4","key":"10.1016\/j.cellsig.2006.09.005_bib83","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/nm1004","volume":"10","author":"Torres","year":"2004","journal-title":"Nat. Med."},{"issue":"4","key":"10.1016\/j.cellsig.2006.09.005_bib84","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1681\/ASN.2004121090","volume":"16","author":"Wang","year":"2005","journal-title":"J. Am. Soc. Nephrol."},{"issue":"10","key":"10.1016\/j.cellsig.2006.09.005_bib85","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1038\/nm935","volume":"9","author":"Gattone","year":"2003","journal-title":"Nat. Med."},{"issue":"3","key":"10.1016\/j.cellsig.2006.09.005_bib86","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1074\/jbc.270.3.1149","volume":"270","author":"Chiono","year":"1995","journal-title":"J. Biol. Chem."},{"issue":"Pt 3","key":"10.1016\/j.cellsig.2006.09.005_bib87","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1042\/bj2970437","volume":"297","author":"Cooper","year":"1994","journal-title":"Biochem. J."},{"issue":"15","key":"10.1016\/j.cellsig.2006.09.005_bib88","doi-asserted-by":"crossref","first-page":"9297","DOI":"10.1074\/jbc.273.15.9297","volume":"273","author":"Fagan","year":"1998","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.cellsig.2006.09.005_bib89","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0092-8674(02)00716-X","volume":"109","author":"Bhunia","year":"2002","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.cellsig.2006.09.005_bib90","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1172\/JCI21753","volume":"114","author":"Chauvet","year":"2004","journal-title":"J. Clin. Invest."},{"issue":"12","key":"10.1016\/j.cellsig.2006.09.005_bib91","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1038\/ncb1326","volume":"7","author":"Li","year":"2005","journal-title":"Nat. Cell Biol."},{"issue":"52","key":"10.1016\/j.cellsig.2006.09.005_bib92","doi-asserted-by":"crossref","first-page":"52763","DOI":"10.1074\/jbc.M309610200","volume":"278","author":"Ma","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.cellsig.2006.09.005_bib93","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0092-8674(00)80148-8","volume":"86","author":"Chen","year":"1996","journal-title":"Cell"},{"issue":"21","key":"10.1016\/j.cellsig.2006.09.005_bib94","doi-asserted-by":"crossref","first-page":"6276","DOI":"10.1093\/emboj\/17.21.6276","volume":"17","author":"Kraut","year":"1998","journal-title":"EMBO J."}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656806002683?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656806002683?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T10:43:09Z","timestamp":1760265789000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0898656806002683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":94,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0898656806002683"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2006.09.005","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cell biology of polycystin-2","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2006.09.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}