{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T03:49:35Z","timestamp":1784260175813,"version":"3.55.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research (CIHR)","doi-asserted-by":"publisher","award":["MOP 107972"],"award-info":[{"award-number":["MOP 107972"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research (CIHR)","doi-asserted-by":"publisher","award":["MOP 89714"],"award-info":[{"award-number":["MOP 89714"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research (CIHR)","doi-asserted-by":"publisher","award":["MOP 119589"],"award-info":[{"award-number":["MOP 119589"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research (CIHR)","doi-asserted-by":"publisher","award":["PLS 95381"],"award-info":[{"award-number":["PLS 95381"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.cellsig.2014.05.009","type":"journal-article","created":{"date-parts":[[2014,5,24]],"date-time":"2014-05-24T08:32:27Z","timestamp":1400920347000},"page":"1935-1942","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Nodal signals via \u03b2-arrestins and RalGTPases to regulate trophoblast invasion"],"prefix":"10.1016","volume":"26","author":[{"given":"Jeffrey","family":"Law","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guihua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Dragan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne-Marie","family":"Postovit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moshmi","family":"Bhattacharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"589\u2013621","key":"10.1016\/j.cellsig.2014.05.009_bb0005","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1146\/annurev.cellbio.19.041603.094522","volume":"19","author":"Schier","year":"2003","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0010","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/onc.2012.608","volume":"33","author":"Quail","year":"2014","journal-title":"Oncogene"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0015","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/1477-7827-7-122","volume":"7","author":"Papageorgiou","year":"2009","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0020","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1038\/onc.2010.55","volume":"29","author":"Lee","year":"2010","journal-title":"Oncogene"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0025","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/nm1448","volume":"12","author":"Topczewska","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0030","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.ajpath.2010.11.066","volume":"178","author":"Nadeem","year":"2011","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0035","doi-asserted-by":"crossref","first-page":"3124","DOI":"10.1242\/jcs.096412","volume":"125","author":"Luo","year":"2012","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0040","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1093\/humrep\/deh849","volume":"20","author":"Tang","year":"2005","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0045","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1749-6632.2010.05944.x","volume":"1221","author":"Tabibzadeh","year":"2011","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0050","doi-asserted-by":"crossref","first-page":"a003459","DOI":"10.1101\/cshperspect.a003459","volume":"1","author":"Schier","year":"2009","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0305","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.biocel.2012.12.021","volume":"45","author":"Quail","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0060","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1038\/emboj.2008.174","volume":"27","author":"Blanchet","year":"2008","journal-title":"EMBO J."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0310","doi-asserted-by":"crossref","first-page":"ra13","DOI":"10.1126\/scisignal.1165027","volume":"1","author":"Blanchet","year":"2008","journal-title":"Sci. Signal."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0070","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1124\/pr.109.002436","volume":"62","author":"Luttrell","year":"2010","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0075","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1146\/annurev.physiol.69.022405.154749","volume":"69","author":"DeWire","year":"2007","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0080","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/ncb821","volume":"4","author":"Bhattacharya","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0085","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.physiol.69.022405.154804","volume":"69","author":"DeFea","year":"2007","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0090","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1126\/science.1083195","volume":"301","author":"Chen","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0095","doi-asserted-by":"crossref","first-page":"34808","DOI":"10.1074\/jbc.M804741200","volume":"283","author":"Finger","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0100","doi-asserted-by":"crossref","first-page":"8221","DOI":"10.1073\/pnas.0812879106","volume":"106","author":"Mythreye","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0105","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.cellsig.2012.10.001","volume":"25","author":"McLean","year":"2013","journal-title":"Cell. Signal."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0110","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1158\/1541-7786.MCR-08-0578","volume":"7","author":"Li","year":"2009","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0115","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1002\/j.1460-2075.1986.tb04485.x","volume":"5","author":"Chardin","year":"1986","journal-title":"EMBO J."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0120","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1152\/physrev.2001.81.1.153","volume":"81","author":"Takai","year":"2001","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0125","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/ncb821","volume":"4","author":"Bhattacharya","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0130","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1042\/BST0321040","volume":"32","author":"Bhattacharya","year":"2004","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0135","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/S0960-9822(98)70327-6","volume":"8","author":"Hofer","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0140","doi-asserted-by":"crossref","first-page":"19008","DOI":"10.1074\/jbc.M112472200","volume":"277","author":"Matsuzaki","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0145","doi-asserted-by":"crossref","first-page":"3629","DOI":"10.1093\/emboj\/18.13.3629","volume":"18","author":"Nakashima","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0150","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1006\/excr.1993.1139","volume":"206","author":"Graham","year":"1993","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0155","doi-asserted-by":"crossref","first-page":"e48237","DOI":"10.1371\/journal.pone.0048237","volume":"7","author":"Quail","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0315","doi-asserted-by":"crossref","first-page":"e56174","DOI":"10.1371\/journal.pone.0056174","volume":"8","author":"Alemayehu","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0165","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1210\/en.2012-2164","volume":"154","author":"Cvetkovic","year":"2013","journal-title":"Endocrinology"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0170","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1586\/eci.11.65","volume":"7","author":"Hannan","year":"2010","journal-title":"Expert. Rev. Clin. Immunol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0175","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1242\/jcs.115.3.455","volume":"115","author":"Luttrell","year":"2002","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0180","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0962-8924(03)00152-1","volume":"13","author":"Feig","year":"2003","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mce.2004.02.006","volume":"225","author":"Tsuchida","year":"2004","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0190","doi-asserted-by":"crossref","first-page":"4362","DOI":"10.1091\/mbc.E09-07-0539","volume":"20","author":"Lee","year":"2009","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0195","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.biocel.2012.01.018","volume":"44","author":"Burch","year":"2012","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0200","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.gde.2009.06.006","volume":"19","author":"Constam","year":"2009","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0205","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1111\/j.1600-0854.2009.00874.x","volume":"10","author":"Constam","year":"2009","journal-title":"Traffic"},{"issue":"Pt 16","key":"10.1016\/j.cellsig.2014.05.009_bb0210","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.1242\/jcs.113.16.2837","volume":"113","author":"Jullien-Flores","year":"2000","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0215","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/978-3-642-41199-1_12","volume":"219","author":"Strungs","year":"2014","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0220","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1093\/molehr\/gah088","volume":"10","author":"Qiu","year":"2004","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0320","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/mrd.22279","volume":"81","author":"Taylor","year":"2013","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0230","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.placenta.2013.01.009","volume":"34","author":"Wang","year":"2013","journal-title":"Placenta"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0235","doi-asserted-by":"crossref","first-page":"R55","DOI":"10.1530\/REP-12-0103","volume":"145","author":"Park","year":"2013","journal-title":"Reproduction"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0240","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1158\/1541-7786.MCR-08-0578","volume":"7","author":"Li","year":"2009","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0245","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.4049\/jimmunol.1003089","volume":"187","author":"Sanchez-Ruiz","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0250","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.physiol.69.022405.154804","volume":"69","author":"DeFea","year":"2007","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0255","doi-asserted-by":"crossref","first-page":"2880","DOI":"10.1242\/jcs.031641","volume":"121","author":"Spiczka","year":"2008","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0260","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1016\/j.yexcr.2013.06.020","volume":"319","author":"Kashatus","year":"2013","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0265","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/(SICI)1526-968X(200004)26:4<265::AID-GENE80>3.0.CO;2-4","volume":"26","author":"Belo","year":"2000","journal-title":"Genesis"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0270","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.biocel.2012.12.021","volume":"45","author":"Quail","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0275","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.1210\/endo.138.9.5403","volume":"138","author":"Caniggia","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0280","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1006\/excr.1994.1237","volume":"214","author":"Graham","year":"1994","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0290","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.devcel.2008.05.004","volume":"15","author":"Choi","year":"2008","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cellsig.2014.05.009_bb0295","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/mrd.22279","volume":"81","author":"Taylor","year":"2014","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.cellsig.2014.05.009_bb0300","doi-asserted-by":"crossref","first-page":"34418","DOI":"10.1074\/jbc.M300573200","volume":"278","author":"Ge","year":"2003","journal-title":"J. Biol. Chem."}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089865681400179X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089865681400179X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T15:28:49Z","timestamp":1649086129000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089865681400179X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":59,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S089865681400179X"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2014.05.009","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nodal signals via \u03b2-arrestins and RalGTPases to regulate trophoblast invasion","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2014.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}