{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:21:39Z","timestamp":1791584499867,"version":"4.3.4"},"reference-count":282,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.cellsig.2017.11.004","type":"journal-article","created":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T04:45:11Z","timestamp":1511498711000},"page":"281-291","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":149,"special_numbering":"C","title":["Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain"],"prefix":"10.1016","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1735-3342","authenticated-orcid":false,"given":"Michy P.","family":"Kelly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cellsig.2017.11.004_bb0005","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1007\/s12035-013-8582-8","volume":"49","author":"Kaplan","year":"2014","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0010","doi-asserted-by":"crossref","first-page":"376","DOI":"10.3389\/fncel.2014.00376","volume":"8","author":"Averaimo","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0015","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1111\/ejn.12543","volume":"39","author":"Nicol","year":"2014","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0020","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.nlm.2014.10.011","volume":"119","author":"Heckman","year":"2015","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0025","doi-asserted-by":"crossref","first-page":"6460","DOI":"10.1523\/JNEUROSCI.5018-12.2013","volume":"33","author":"Luo","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0030","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1159\/000065431","volume":"11","author":"Fiscus","year":"2002","journal-title":"Neurosignals"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0035","doi-asserted-by":"crossref","first-page":"13952","DOI":"10.1523\/JNEUROSCI.4986-08.2008","volume":"28","author":"Favilla","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0040","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.neuroscience.2006.09.026","volume":"144","author":"Kanes","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0045","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/sj.npp.1301099","volume":"32","author":"Kelly","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0050","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1111\/j.1460-9568.2011.07606.x","volume":"33","author":"Merz","year":"2011","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0055","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3233\/JHD-120023","volume":"1","author":"Giralt","year":"2012","journal-title":"J. Huntingtons Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0060","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/mp.2008.124","volume":"14","author":"Kelly","year":"2009","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0065","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.bcp.2017.06.116","volume":"141","author":"Apple","year":"2017","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0070","series-title":"In: Interventions to Prevent Age-related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer's-Type Dementia","author":"Kane","year":"2017"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0075","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nrneurol.2016.200","volume":"13","author":"Ffytche","year":"2017","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0080","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.cnur.2017.04.009","volume":"52","author":"Dean","year":"2017","journal-title":"Nurs. Clin. N. Am."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0085","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1126\/science.1071550","volume":"296","author":"Neves","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2013.04.027","volume":"1518","author":"Chen","year":"2013","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0095","doi-asserted-by":"crossref","first-page":"517","DOI":"10.18388\/abp.2000_3975","volume":"47","author":"Kobialka","year":"2000","journal-title":"Acta Biochim. Pol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0100","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1152\/physrev.00030.2010","volume":"91","author":"Francis","year":"2011","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0105","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1111\/j.1471-4159.1992.tb11357.x","volume":"58","author":"Cowburn","year":"1992","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0110","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/0306-4522(92)90067-C","volume":"46","author":"Hara","year":"1992","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0115","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0006-8993(93)90428-P","volume":"618","author":"Sugawa","year":"1993","journal-title":"Brain Res."},{"issue":"Suppl. 1","key":"10.1016\/j.cellsig.2017.11.004_bb0120","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0167-4943(05)80069-X","volume":"19","author":"Sugawa","year":"1994","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0125","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0047-6374(81)90132-9","volume":"15","author":"Puri","year":"1981","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0130","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/978-1-4684-8893-7_13","volume":"113","author":"Makman","year":"1978","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0135","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0006-8993(80)91017-3","volume":"192","author":"Makman","year":"1980","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0140","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0006-8993(95)01117-X","volume":"704","author":"Araki","year":"1995","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0145","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.4049\/jimmunol.125.4.1665","volume":"125","author":"Tam","year":"1980","journal-title":"J. Immunol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0150","first-page":"651","volume":"55","author":"Birkenfeld","year":"1984","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0155","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0047-6374(90)90131-X","volume":"52","author":"Fulop","year":"1990","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0160","first-page":"351","volume":"39","author":"Kostromin","year":"1984","journal-title":"Z. Alternsforsch."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0165","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jep.2006.11.016","volume":"111","author":"Hu","year":"2007","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0170","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0197-4580(94)90151-1","volume":"15","author":"Grammas","year":"1994","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0175","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S0006-8993(01)03009-8","volume":"922","author":"Martinez","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0180","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.neuroscience.2012.12.002","volume":"231","author":"Titus","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0185","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0006-8993(78)90070-7","volume":"139","author":"Schmidt","year":"1978","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0190","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF02432185","volume":"1","author":"Austin","year":"1978","journal-title":"Age"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0195","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0047-6374(74)90003-7","volume":"3","author":"Zimmerman","year":"1974","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0200","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0047-6374(75)90038-X","volume":"4","author":"Berg","year":"1975","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0205","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0896-6273(03)00694-9","volume":"40","author":"Ramos","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0210","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/nature10243","volume":"476","author":"Wang","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0215","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/j.neurobiolaging.2012.10.006","volume":"34","author":"Vandesquille","year":"2013","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0220","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0006-8993(01)02409-X","volume":"903","author":"Karege","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0225","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0304-3940(01)02358-8","volume":"315","author":"Karege","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0230","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0047-6374(97)01899-X","volume":"97","author":"Laviada","year":"1997","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0235","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF02815141","volume":"26","author":"Cashman","year":"1995","journal-title":"Mol. Chem. Neuropathol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0240","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/0306-3623(91)90237-Z","volume":"22","author":"Stancheva","year":"1991","journal-title":"Gen. Pharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0245","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF02815117","volume":"35","author":"Chalimoniuk","year":"1998","journal-title":"Mol. Chem. Neuropathol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0250","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.cellsig.2013.10.007","volume":"26","author":"Kelly","year":"2014","journal-title":"Cell. Signal."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0255","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.1073\/pnas.1322360111","volume":"111","author":"Carlyle","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0260","series-title":"Cyclic Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Disease","article-title":"Putting together the pieces of phosphodiesterase distribution patterns in the brain: a jigsaw puzzle of cyclic nucleotide regulation","author":"Kelly","year":"2014"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0265","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1248\/bpb.19.300","volume":"19","author":"Tohda","year":"1996","journal-title":"Biol. Pharm. Bull."},{"issue":"1017","key":"10.1016\/j.cellsig.2017.11.004_bb0270","first-page":"e1011","volume":"33","author":"De Jager","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0275","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1080\/13543784.2017.1364360","volume":"26","author":"Prickaerts","year":"2017","journal-title":"Expert Opin. Investig. Drugs"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0280","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1358\/mf.1998.20.5.485701","volume":"20","author":"Kato","year":"1998","journal-title":"Methods Find. Exp. Clin. Pharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0285","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/syn.10067","volume":"44","author":"Harada","year":"2002","journal-title":"Synapse"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0290","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/0169-328X(96)00098-8","volume":"41","author":"Asanuma","year":"1996","journal-title":"Brain Res. Mol. Brain Res."},{"issue":"Suppl. 1","key":"10.1016\/j.cellsig.2017.11.004_bb0295","doi-asserted-by":"crossref","first-page":"S252","DOI":"10.1038\/sj.bjp.0706495","volume":"147","author":"Boswell-Smith","year":"2006","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0300","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1093\/gerona\/glw078","volume":"71","author":"Driscoll","year":"2016","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0305","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3233\/JAD-122371","volume":"35","author":"Vercambre","year":"2013","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0310","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.neuroscience.2008.03.038","volume":"153","author":"Costa","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0315","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.exger.2010.11.034","volume":"46","author":"Leite","year":"2011","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0320","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.neuroscience.2011.11.053","volume":"202","author":"Vila-Luna","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0325","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1007\/s11357-012-9509-4","volume":"35","author":"Shukitt-Hale","year":"2013","journal-title":"Age (Dordr.)"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0330","doi-asserted-by":"crossref","first-page":"158","DOI":"10.3109\/19390211.2011.569514","volume":"8","author":"Richter","year":"2011","journal-title":"J. Diet Suppl."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0335","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.brainres.2008.02.108","volume":"1216","author":"Domek-Lopacinska","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0340","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.neuropharm.2016.12.006","volume":"116","author":"Yanai","year":"2017","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0345","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.biopha.2017.01.059","volume":"88","author":"Kumar","year":"2017","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0350","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ejphar.2010.02.036","volume":"634","author":"Drott","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0355","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.neuropharm.2008.06.025","volume":"55","author":"de Lima","year":"2008","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0360","doi-asserted-by":"crossref","first-page":"5280","DOI":"10.1073\/pnas.96.9.5280","volume":"96","author":"Bach","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0365","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1111\/j.1601-183X.2012.00836.x","volume":"11","author":"Tsai","year":"2012","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0370","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/S0006-8993(99)01444-4","volume":"834","author":"Blum-Degen","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0375","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0197-0186(02)00098-0","volume":"42","author":"Jesko","year":"2003","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0380","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.neurobiolaging.2003.07.003","volume":"25","author":"Liu","year":"2004","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0385","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0306-4522(03)00210-0","volume":"119","author":"Liu","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0390","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1002\/hipo.20085","volume":"15","author":"Liu","year":"2005","journal-title":"Hippocampus"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0395","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.neulet.2004.08.013","volume":"370","author":"Strosznajder","year":"2004","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0400","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1111\/j.1460-9568.1995.tb00673.x","volume":"7","author":"Vallebuona","year":"1995","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0405","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1006\/bbrc.1995.2537","volume":"215","author":"Mollace","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0410","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0304-3940(00)01377-X","volume":"291","author":"Yu","year":"2000","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0415","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0306-4522(02)00082-9","volume":"112","author":"Law","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0420","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0006-8993(01)02588-4","volume":"907","author":"Ibarra","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0425","first-page":"179","volume":"49","author":"Paul","year":"2005","journal-title":"Indian J. Physiol. Pharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0430","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3389\/fnbeh.2016.00166","volume":"10","author":"Matsumoto","year":"2016","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0435","doi-asserted-by":"crossref","first-page":"M95","DOI":"10.1093\/gerona\/51A.3.M95","volume":"51","author":"Davis","year":"1996","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0440","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.exger.2013.12.001","volume":"50","author":"Marksteiner","year":"2014","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0445","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1159\/000111994","volume":"25","author":"Nilsson","year":"2008","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0450","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3109\/07853890.2012.663929","volume":"45","author":"Hiltunen","year":"2013","journal-title":"Ann. Med."},{"issue":"670","key":"10.1016\/j.cellsig.2017.11.004_bb0455","first-page":"e671","volume":"124","author":"Daniels","year":"2011","journal-title":"Am. J. Med."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0460","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1212\/WNL.0000000000000820","volume":"83","author":"van Vliet","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0465","doi-asserted-by":"crossref","first-page":"e44569","DOI":"10.1371\/journal.pone.0044569","article-title":"Edinburgh Type 2 diabetes study","volume":"7","author":"Feinkohl","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0470","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.amjcard.2006.02.062","volume":"98","author":"Gunstad","year":"2006","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0475","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.neurobiolaging.2004.08.011","volume":"26","author":"Kawamoto","year":"2005","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0480","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neurobiolaging.2004.08.013","volume":"26","author":"Scavone","year":"2005","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0485","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1101\/lm.541307","volume":"14","author":"Piedrafita","year":"2007","journal-title":"Learn. Mem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0490","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.bbr.2012.10.060","volume":"240","author":"Palmeri","year":"2013","journal-title":"Behav. Brain Res."},{"issue":"625","key":"10.1016\/j.cellsig.2017.11.004_bb0495","first-page":"e611","volume":"33","author":"Orejana","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0500","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3233\/NRE-131022","volume":"34","author":"Devan","year":"2014","journal-title":"NeuroRehabilitation"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0505","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/S0006-8993(99)01220-2","volume":"824","author":"Yamamoto-Sasaki","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0510","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.neurobiolaging.2007.03.023","volume":"29","author":"Porte","year":"2008","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0515","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1093\/gerona\/glq094","volume":"65","author":"Xu","year":"2010","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0520","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1523\/JNEUROSCI.3453-12.2013","volume":"33","author":"Dagnas","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0525","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.expneurol.2005.05.014","volume":"195","author":"Hattiangady","year":"2005","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0530","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.brainres.2005.06.045","volume":"1054","author":"Kudo","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0535","volume":"6","author":"Yu","year":"2017","journal-title":"elife"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0540","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0006-8993(94)91017-0","volume":"636","author":"O'Neill","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0545","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0006-8993(94)91692-6","volume":"644","author":"Schnecko","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0550","first-page":"501","volume":"317","author":"Ohm","year":"1989","journal-title":"Prog. Clin. Biol. Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0555","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0006-8993(91)90512-T","volume":"540","author":"Ohm","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0560","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0006-8993(96)00724-X","volume":"737","author":"Bonkale","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0565","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0197-4580(97)80307-7","volume":"18","author":"Ohm","year":"1997","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0570","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/0304-3940(92)90324-Z","volume":"141","author":"Cowburn","year":"1992","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0575","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0169-328X(98)00069-2","volume":"57","author":"Brinton","year":"1998","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0580","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0006-8993(90)90168-B","volume":"511","author":"Dewar","year":"1990","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0585","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0925-4439(00)00083-1","volume":"1535","author":"Yamamoto","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0590","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/BF01291889","volume":"104","author":"Yamamoto","year":"1997","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0595","doi-asserted-by":"crossref","first-page":"11390","DOI":"10.1523\/JNEUROSCI.0757-12.2012","volume":"32","author":"Chen","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0600","doi-asserted-by":"crossref","first-page":"269","DOI":"10.3233\/JAD-122236","volume":"38","author":"Zhang","year":"2014","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0605","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0006-8993(98)01307-9","volume":"818","author":"Bonkale","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0610","first-page":"263","author":"Kim","year":"2001","journal-title":"J. Neural Transm. Suppl."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0615","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1111\/j.1471-4159.2007.04942.x","volume":"103","author":"Liang","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0620","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1016\/j.bbadis.2013.03.004","volume":"1842","author":"Du","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0625","doi-asserted-by":"crossref","first-page":"13217","DOI":"10.1073\/pnas.172504199","volume":"99","author":"Vitolo","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0630","doi-asserted-by":"crossref","first-page":"14639","DOI":"10.1074\/jbc.M110.204453","volume":"286","author":"Shi","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0635","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1016\/j.neurobiolaging.2007.12.004","volume":"30","author":"Wang","year":"2009","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0640","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1172\/JCI22831","volume":"114","author":"Gong","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0645","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.neuropharm.2012.06.048","volume":"64","author":"Sierksma","year":"2013","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0650","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.neuropharm.2013.09.015","volume":"77","author":"Sierksma","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0655","doi-asserted-by":"crossref","first-page":"17380","DOI":"10.18632\/oncotarget.8041","volume":"7","author":"Wang","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0660","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1017\/S1461145711000836","volume":"15","author":"Wang","year":"2012","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0665","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s00213-010-1943-3","volume":"212","author":"Cheng","year":"2010","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0670","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1016\/j.neurobiolaging.2013.03.011","volume":"34","author":"Perez-Gonzalez","year":"2013","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0675","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1750-1326-7-50","volume":"7","author":"Saito","year":"2012","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0680","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.neuroscience.2015.07.087","volume":"305","author":"Eslamizade","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0685","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.bbrc.2016.12.140","volume":"483","author":"Frykman","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0690","unstructured":"I. McPhee, L.C. Gibson, J. Kewney, C. Darroch, P.A. Stevens, D. Spinks, A. Cooreman, S.J. MacKenzie, 33 (2005) 1330\u20131332."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0695","unstructured":"N. Zaldua, M. Gastineau, M. Hoshino, F. Lezoualc'h, J.L. Zugaza, 581 (2007) 5814\u20135818."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0700","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/ncb1007","volume":"5","author":"Maillet","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0705","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/nan.12203","volume":"41","author":"Ugarte","year":"2015","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0710","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13195-017-0245-y","volume":"9","author":"Hesse","year":"2017","journal-title":"Alzheimers Res. Ther."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0715","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0006-8993(99)01981-2","volume":"846","author":"Martinez","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0720","doi-asserted-by":"crossref","first-page":"7486","DOI":"10.1523\/JNEUROSCI.19-17-07486.1999","volume":"19","author":"Jicha","year":"1999","journal-title":"J. Neurosci."},{"issue":"3","key":"10.1016\/j.cellsig.2017.11.004_bb0725","first-page":"389","volume":"45","author":"Wang","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0730","first-page":"256","volume":"4","author":"Robertson","year":"1993","journal-title":"Dementia"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0735","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1007\/s00702-005-0421-2","volume":"113","author":"Zhang","year":"2006","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0740","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.bbr.2011.08.015","volume":"226","author":"Eftekharzadeh","year":"2012","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0745","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.physbeh.2015.05.029","volume":"149","author":"Amini","year":"2015","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0750","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0304-3940(95)12288-5","volume":"203","author":"Ueda","year":"1996","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0755","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1750-1326-6-60","volume":"6","author":"Pugazhenthi","year":"2011","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0760","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1038\/npp.2011.107","volume":"36","author":"Yiu","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0765","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/psyg.12021","volume":"13","author":"Taguchi","year":"2013","journal-title":"Psychogeriatrics"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0770","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1007\/s13311-017-0512-4","volume":"14","author":"Tai","year":"2017","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0775","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/acn3.79","volume":"1","author":"Maki","year":"2014","journal-title":"Ann. Clin. Transl. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0780","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0531-5131(03)00104-3","volume":"1251","author":"Perez-Torres","year":"2003","journal-title":"Int. Congr. Ser."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0785","doi-asserted-by":"crossref","first-page":"16877","DOI":"10.1073\/pnas.0908706106","volume":"106","author":"Smith","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0790","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/2211-5463.12156","volume":"7","author":"Cameron","year":"2017","journal-title":"FEBS Open Bio"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0795","first-page":"591","volume":"4","author":"Bate","year":"2015","journal-title":"Biology (Basel)"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0800","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1046\/j.1432-1327.1998.2520542.x","volume":"252","author":"Zheng-Fischhofer","year":"1998","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0805","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1021\/bi981874p","volume":"38","author":"Schneider","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0810","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1006\/bbrc.1995.2571","volume":"215","author":"Raghunandan","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0815","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1023\/A:1006977127422","volume":"19","author":"Shea","year":"1999","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0820","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.neurobiolaging.2005.03.024","volume":"27","author":"Sebastiani","year":"2006","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0825","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1001\/archneur.64.3.456","volume":"64","author":"McLachlan","year":"2007","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0830","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/S0014-4886(03)00042-6","volume":"182","author":"Perez-Torres","year":"2003","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0835","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.1111\/j.1460-9568.2007.05589.x","volume":"25","author":"Reyes-Irisarri","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0840","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3233\/JAD-2009-1087","volume":"17","author":"Arendash","year":"2009","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0845","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.neuroscience.2006.07.021","volume":"142","author":"Arendash","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0850","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.neurobiolaging.2014.03.027","volume":"35","author":"Laurent","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0855","first-page":"115","volume":"65","author":"Valikovics","year":"2012","journal-title":"Ideggyogy. Sz."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0860","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1532-5415.1989.tb05682.x","volume":"37","author":"Thal","year":"1989","journal-title":"J. Am. Geriatr. Soc."},{"issue":"1","key":"10.1016\/j.cellsig.2017.11.004_bb0865","author":"Szatmari","year":"2003","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0870","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/JGP.0b013e31819431ea","volume":"17","author":"Arai","year":"2009","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0875","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1447-0594.2012.00866.x","volume":"13","author":"Sakurai","year":"2013","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0880","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12883-017-0800-y","volume":"17","author":"Tai","year":"2017","journal-title":"BMC Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0885","volume":"9","author":"Ihara","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0890","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1159\/000017197","volume":"10","author":"Treves","year":"1999","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0895","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/0006-3223(92)90296-C","volume":"32","author":"Saletu","year":"1992","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0900","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.neurobiolaging.2006.04.009","volume":"28","author":"Costa","year":"2007","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0905","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.bbrc.2011.04.068","volume":"408","author":"Park","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0910","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1001\/archneurol.2012.1070","volume":"69","author":"Soares","year":"2012","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0915","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/s00415-016-8378-7","volume":"264","author":"Tynkkynen","year":"2017","journal-title":"J. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0920","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.3233\/JAD-141809","volume":"44","author":"Tynkkynen","year":"2015","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0925","volume":"94","author":"Hilal","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0930","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1212\/WNL.0b013e318266fa70","volume":"79","author":"Hu","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0935","doi-asserted-by":"crossref","first-page":"359","DOI":"10.3233\/JAD-160635","volume":"55","author":"Kara","year":"2017","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0940","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1097\/WNR.0b013e328326f82f","volume":"20","author":"Kondziella","year":"2009","journal-title":"Neuroreport"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0945","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1136\/jnnp-2014-309968","volume":"87","author":"Mirza","year":"2016","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0950","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1447-0594.2009.00526.x","volume":"9","author":"Naito","year":"2009","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0955","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/WAD.0b013e31826d597a","article-title":"I. Alzheimer's disease neuroimaging","volume":"27","author":"Llano","year":"2013","journal-title":"Alzheimer Dis. Assoc. Disord."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0960","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/joim.12621","volume":"282","author":"Holm","year":"2017","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0965","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.biopsych.2009.01.032","volume":"65","author":"Buerger","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0970","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.biopsych.2011.01.036","volume":"70","author":"Schneider","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0975","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0304-3940(01)02214-5","volume":"312","author":"Abe","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0980","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0306-4522(98)00383-2","volume":"89","author":"Yew","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb0985","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1523\/JNEUROSCI.21-04-01179.2001","volume":"21","author":"Combs","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0990","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0304-3940(95)11323-O","volume":"187","author":"Bonkale","year":"1995","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.cellsig.2017.11.004_bb0995","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.nbd.2004.07.022","volume":"17","author":"Baltrons","year":"2004","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1000","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1006\/nbdi.2002.0492","volume":"10","author":"Baltrons","year":"2002","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1005","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.neuint.2012.07.017","volume":"61","author":"Duszczyk","year":"2012","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1010","doi-asserted-by":"crossref","first-page":"6887","DOI":"10.1523\/JNEUROSCI.5291-04.2005","volume":"25","author":"Puzzo","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1015","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1006\/exnr.1999.7055","volume":"157","author":"Paris","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1020","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1046\/j.1471-4159.1999.0730532.x","volume":"73","author":"Mattson","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1025","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0306-4522(00)00243-8","volume":"99","author":"Wirtz-Brugger","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1030","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1523\/JNEUROSCI.2774-16.2016","volume":"37","author":"Prieto","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1035","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.bbr.2013.05.017","volume":"250","author":"Zhang","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1040","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/med.20177","volume":"31","author":"Oz","year":"2011","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1045","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.ejmech.2012.12.009","volume":"60","author":"Fiorito","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1050","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.neurobiolaging.2013.09.002","volume":"35","author":"Puzzo","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1055","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1111\/j.1476-5381.2011.01517.x","volume":"164","author":"Cuadrado-Tejedor","year":"2011","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1060","doi-asserted-by":"crossref","first-page":"8075","DOI":"10.1523\/JNEUROSCI.0864-09.2009","volume":"29","author":"Puzzo","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1065","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.neuropharm.2012.06.052","volume":"64","author":"Garcia-Barroso","year":"2013","journal-title":"Neuropharmacology"},{"issue":"Pt 1","key":"10.1016\/j.cellsig.2017.11.004_bb1070","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1042\/bj3110045","volume":"311","author":"Barger","year":"1995","journal-title":"Biochem. J."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1075","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1038\/nature14332","volume":"519","author":"Lee","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1080","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.brainres.2016.04.011","volume":"1642","author":"Li","year":"2016","journal-title":"Brain Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1085","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1016\/j.neurobiolaging.2014.03.023","volume":"35","author":"Kroker","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1090","doi-asserted-by":"crossref","first-page":"413","DOI":"10.2174\/1567205011666140505100858","volume":"11","author":"Schwam","year":"2014","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1095","doi-asserted-by":"crossref","first-page":"17301","DOI":"10.1074\/jbc.M010450200","volume":"276","author":"Tong","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1100","doi-asserted-by":"crossref","first-page":"13293","DOI":"10.1073\/pnas.1109297108","volume":"108","author":"Muller","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1105","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0014-5793(97)00753-9","volume":"412","author":"Giambarella","year":"1997","journal-title":"FEBS Lett."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1110","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.neuroscience.2005.06.057","volume":"135","author":"Echeverria","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1115","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1002\/j.1460-2075.1996.tb00604.x","volume":"15","author":"Ikezu","year":"1996","journal-title":"EMBO J."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1120","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1159\/000333341","volume":"10","author":"Saura","year":"2012","journal-title":"Neurodegener. Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1125","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/j.1471-4159.2007.04704.x","volume":"103","author":"Arvanitis","year":"2007","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1130","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1155\/2009\/618619","volume":"27","author":"Satoh","year":"2009","journal-title":"Dis. Markers"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1135","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/hmg\/ddg046","volume":"12","author":"Gines","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1140","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.neuron.2016.10.064","volume":"92","author":"Beaumont","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1145","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1172\/JCI85594","volume":"127","author":"Tanaka","year":"2017","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1150","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.neuroscience.2003.11.009","volume":"123","author":"Hebb","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1155","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1128\/MCB.01434-12","volume":"33","author":"Lin","year":"2013","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1160","doi-asserted-by":"crossref","first-page":"4232","DOI":"10.1093\/hmg\/ddr351","volume":"20","author":"Giralt","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1165","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1002\/hipo.22128","volume":"23","author":"Giralt","year":"2013","journal-title":"Hippocampus"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1170","doi-asserted-by":"crossref","first-page":"3883","DOI":"10.1093\/hmg\/dds216","volume":"21","author":"Feyeux","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073664","volume":"8","author":"Saavedra","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1180","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1212\/WNL.0000000000000037","volume":"82","author":"Ahmad","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1185","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.jns.2016.07.033","volume":"368","author":"Wilson","year":"2016","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1190","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1001\/jamaneurol.2014.1954","volume":"71","author":"Russell","year":"2014","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1195","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.nbd.2012.11.016","volume":"52","author":"Leuti","year":"2013","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1200","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1111\/j.1460-9568.2004.03796.x","volume":"20","author":"Hu","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1205","doi-asserted-by":"crossref","first-page":"333","DOI":"10.3233\/JHD-140129","volume":"3","author":"Miller","year":"2014","journal-title":"J. Huntingtons Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1210","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1124\/jpet.116.237388","volume":"360","author":"Harada","year":"2017","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0013417","volume":"5","author":"Giampa","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1220","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.nbd.2009.02.014","volume":"34","author":"Giampa","year":"2009","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1225","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1093\/hmg\/ddr552","volume":"21","author":"Giralt","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1230","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00441-004-0938-y","volume":"318","author":"Schober","year":"2004","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1235","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1111\/ggi.12123","volume":"14","author":"Qi","year":"2014","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1240","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s10048-016-0497-x","volume":"18","author":"Kaut","year":"2017","journal-title":"Neurogenetics"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1245","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1002\/mds.26345","volume":"30","author":"Azuma","year":"2015","journal-title":"Mov. Disord."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1250","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1093\/brain\/awv219","volume":"138","author":"Niccolini","year":"2015","journal-title":"Brain"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1255","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1111\/j.1460-9568.2006.04816.x","volume":"23","author":"Galati","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1260","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/ana.20402","volume":"57","author":"Stefani","year":"2005","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1265","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/978-3-211-45295-0_60","author":"Stefani","year":"2006","journal-title":"J. Neural Transm. Suppl."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1270","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF02260966","volume":"7","author":"Bockelmann","year":"1994","journal-title":"J. Neural Transm. Park. Dis. Dement. Sect."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1275","first-page":"647","volume":"56","author":"Chalimoniuk","year":"2004","journal-title":"Pol. J. Pharmacol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1280","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.parkreldis.2011.07.003","volume":"17","author":"Brodacki","year":"2011","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1285","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0022-510X(97)00267-0","volume":"155","author":"Navarro","year":"1998","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1290","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF01276464","volume":"100","author":"Ikeda","year":"1995","journal-title":"J. Neural Transm. Gen. Sect."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1295","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0032664","volume":"7","author":"Oeckl","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1300","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1212\/WNL.36.1.89","volume":"36","author":"Volicer","year":"1986","journal-title":"Neurology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1305","doi-asserted-by":"crossref","first-page":"E34","DOI":"10.1073\/pnas.1312701111","volume":"111","author":"Muda","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1310","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.expneurol.2013.11.009","volume":"252","author":"Kim","year":"2014","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1315","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/j.1460-9568.2008.06387.x","volume":"28","author":"Giorgi","year":"2008","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1320","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.neuint.2014.10.004","volume":"79","author":"Sancesario","year":"2014","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1325","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/j.1460-9568.2004.03566.x","volume":"20","author":"Sancesario","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1330","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1179\/135100001101536436","volume":"6","author":"Barthwal","year":"2001","journal-title":"Redox Rep."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1335","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1007\/s00213-017-4587-8","volume":"234","author":"Hufgard","year":"2017","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1340","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1111\/jnc.12049","volume":"123","author":"Oliva","year":"2012","journal-title":"J. Neurochem."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1345","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1254\/jphs.10R01FM","volume":"114","author":"Nishi","year":"2010","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1350","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.neuint.2007.02.002","volume":"50","author":"Chalimoniuk","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1355","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.bbrc.2004.09.028","volume":"324","author":"Chalimoniuk","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1360","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.neuroscience.2014.12.008","volume":"286","author":"Sharma","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1365","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.peptides.2013.09.005","volume":"49","author":"Zhao","year":"2013","journal-title":"Peptides"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1370","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.expneurol.2007.02.010","volume":"211","author":"Yang","year":"2008","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1375","series-title":"Encyclopedia of Signaling Molecules","first-page":"1","article-title":"Pde11a","author":"Kelly","year":"2016"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1380","author":"Pathak","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1385","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1038\/npp.2016.106","volume":"41","author":"Hegde","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1390","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.neuroscience.2016.08.019","volume":"335","author":"Hegde","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.cellsig.2017.11.004_bb1395","doi-asserted-by":"crossref","first-page":"8457","DOI":"10.1073\/pnas.1000730107","volume":"107","author":"Kelly","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1400","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0047-6374(75)90010-X","volume":"4","author":"Zimmerman","year":"1975","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1405","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0047-6374(77)90006-9","volume":"6","author":"Puri","year":"1977","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.cellsig.2017.11.004_bb1410","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/0197-0186(94)90026-4","volume":"25","author":"Giorgi","year":"1994","journal-title":"Neurochem. Int."}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656817303005?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656817303005?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T00:28:27Z","timestamp":1719620907000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0898656817303005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":282,"alternative-id":["S0898656817303005"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2017.11.004","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2017.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}