{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T14:28:24Z","timestamp":1793888904225,"version":"4.8.0"},"reference-count":136,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T00:00:00Z","timestamp":1652745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/J500495\/1"],"award-info":[{"award-number":["MR\/J500495\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.cellsig.2022.110355","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T13:28:19Z","timestamp":1652794099000},"page":"110355","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":126,"special_numbering":"C","title":["The Vitamin D\/Vitamin D receptor (VDR) axis in muscle atrophy and sarcopenia"],"prefix":"10.1016","volume":"96","author":[{"given":"Shelby E.","family":"Bollen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph J.","family":"Bass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Hewison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Atherton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cellsig.2022.110355_bb0005","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.cmet.2014.12.021","article-title":"Muscle as a \u201cmediator\u201d of systemic metabolism","volume":"21","author":"Baskin","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0010","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1016\/S0140-6736(19)31138-9","article-title":"Sarcopenia","volume":"393","author":"Cruz-Jentoft","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.cellsig.2022.110355_bb0015","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2016.00361","article-title":"Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown, and insulin resistance\u2014a qualitative review","volume":"7","author":"Rudrappa","year":"2016","journal-title":"Front. Physiol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0020","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.freeradbiomed.2018.08.037","article-title":"Impaired proteostasis during skeletal muscle aging","volume":"132","author":"Fernando","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.cellsig.2022.110355_bb0025","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/s41467-020-20123-1","article-title":"Mechanisms of muscle atrophy and hypertrophy: implications in health and disease","volume":"12","author":"Sartori","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cellsig.2022.110355_bb0030","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1194\/jlr.R031534","article-title":"Cytochrome P450-mediated metabolism of vitamin D","volume":"55","author":"Jones","year":"2014","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0035","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.tibs.2004.10.005","article-title":"Enzymes involved in the activation and inactivation of vitamin D","volume":"29","author":"Prosser","year":"2004","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.cellsig.2022.110355_bb0040","first-page":"888","article-title":"Extrarenal expression of 25-hydroxyvitamin D 3 -1\u03b1-hydroxylase 1","volume":"86","author":"Zehnder","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0045","doi-asserted-by":"crossref","first-page":"8239","DOI":"10.1038\/s41598-020-65067-0","article-title":"Regulation of vitamin D system in skeletal muscle and resident myogenic stem cell during development, maturation, and ageing","volume":"10","author":"Srikuea","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cellsig.2022.110355_bb0050","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jsbmb.2013.11.004","article-title":"Fundamentals of vitamin D hormone-regulated gene expression","volume":"144","author":"Pike","year":"2014","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0055","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jsbmb.2013.12.009","article-title":"Regulation of the extrarenal CYP27B1-hydroxylase","volume":"144","author":"Adams","year":"2014","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0060","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Deficiency","volume":"357","author":"Holick","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cellsig.2022.110355_bb0065","article-title":"Myogenic, genomic and non-genomic influences of the vitamin D axis in skeletal muscle","author":"Bollen","year":"2020","journal-title":"Cell Biochem. Funct."},{"key":"10.1016\/j.cellsig.2022.110355_bb0070","article-title":"Effect of vitamin D monotherapy on indices of sarcopenia in community-dwelling older adults: a systematic review and meta-analysis","author":"Prokopidis","year":"2022","journal-title":"J. Cachexia. Sarcopenia Muscle"},{"key":"10.1016\/j.cellsig.2022.110355_bb0075","author":"NICE (National Institute for Health and Care Excellence)"},{"key":"10.1016\/j.cellsig.2022.110355_bb0080","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1359\/jbmr.2004.19.2.265","article-title":"Vitamin D receptor expression in human muscle tissue decreases with age","volume":"19","author":"Bischoff-Ferrari","year":"2004","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0085","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1172\/JCI112134","article-title":"Aging decreases the capacity of human skin to produce vitamin D3","volume":"76","author":"MacLaughlin","year":"1985","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cellsig.2022.110355_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2020.105650","article-title":"The vitamin D activator CYP27B1 is upregulated in muscle fibers in denervating disease and can track progression in amyotrophic lateral sclerosis","volume":"200","author":"Si","year":"2020","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0095","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1007\/s11914-014-0204-5","article-title":"Therapies for musculoskeletal disease: can we treat two birds with one stone?","volume":"12","author":"Girgis","year":"2014","journal-title":"Curr. Osteoporos. Rep."},{"key":"10.1016\/j.cellsig.2022.110355_bb0100","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/jbmr.4441","article-title":"Vitamin D receptor signaling attenuates skeletal muscle atrophy by suppressing renin-angiotensin system","volume":"37","author":"Li","year":"2022","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0105","doi-asserted-by":"crossref","first-page":"736","DOI":"10.3390\/nu13030736","article-title":"Vitamin D deficiency is associated with handgrip strength, nutritional status and T2DM in community-dwelling older Mexican women: a cross-sectional study","volume":"13","author":"Mendoza-Garc\u00e9s","year":"2021","journal-title":"Nutrients."},{"key":"10.1016\/j.cellsig.2022.110355_bb0110","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/21551197.2013.867825","article-title":"Vitamin D status is associated with grip strength in centenarians","volume":"33","author":"Haslam","year":"2014","journal-title":"J. Nutr. Gerontol. Geriatr."},{"key":"10.1016\/j.cellsig.2022.110355_bb0115","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/cen.13952","article-title":"Vitamin D is related to handgrip strength in adult men aged 50 years and over: a population study from the TCLSIH cohort study","volume":"90","author":"Wang","year":"2019","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0120","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/1471-2393-13-237","article-title":"Physical performance and 25-hydroxyvitamin D: a cross-sectional study of pregnant Swedish and Somali immigrant women and new mothers","volume":"13","author":"Kalliokoski","year":"2013","journal-title":"BMC Pregnancy Childbirth."},{"key":"10.1016\/j.cellsig.2022.110355_bb0125","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1249\/MSS.0b013e31826c9a78","article-title":"25(OH) Vitamin D is associated with greater muscle strength in healthy men and women","volume":"45","author":"Grimaldi","year":"2013","journal-title":"Med. Sci. Sports Exerc."},{"key":"10.1016\/j.cellsig.2022.110355_bb0130","doi-asserted-by":"crossref","first-page":"e34950","DOI":"10.1371\/journal.pone.0034950","article-title":"Vitamin D and physical performance in elderly subjects: the Pro.V.A study. Ruiz JR, editor","volume":"7","author":"Toffanello","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cellsig.2022.110355_bb0135","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s40520-016-0678-3","article-title":"Prevalence of clinically relevant muscle weakness and its association with vitamin D status among older adults in Ecuador","volume":"29","author":"Orces","year":"2017","journal-title":"Aging Clin. Exp. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0140","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1089\/jwh.2010.2606","article-title":"Serum 25-hydroxyvitamin D and physical performance in postmenopausal women","volume":"20","author":"Michael","year":"2011","journal-title":"J. Women\u2019s Health"},{"key":"10.1016\/j.cellsig.2022.110355_bb0145","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.2147\/CIA.S222143","article-title":"Vitamin D deficiency is associated with impaired muscle strength and physical performance in community-dwelling older adults: findings from the english longitudinal study of ageing","volume":"14","author":"Aspell","year":"2019","journal-title":"Clin. Interv. Aging"},{"key":"10.1016\/j.cellsig.2022.110355_bb0150","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1007\/s00198-008-0749-1","article-title":"Sex-specific association of serum vitamin D levels with physical function in older adults","volume":"20","author":"Dam","year":"2009","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.cellsig.2022.110355_bb0155","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1093\/ajcn\/80.3.752","article-title":"Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged \u226560 y","volume":"80","author":"Bischoff-Ferrari","year":"2004","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.cellsig.2022.110355_bb0160","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11657-017-0378-4","article-title":"The effect of vitamin D status on pain, lower limb strength and knee function during balance recovery in people with knee osteoarthritis: an exploratory study","volume":"12","author":"Levinger","year":"2017","journal-title":"Arch. Osteoporos."},{"key":"10.1016\/j.cellsig.2022.110355_bb0165","doi-asserted-by":"crossref","first-page":"E1483","DOI":"10.1210\/jc.2013-1698","article-title":"Vitamin D status is associated with functional limitations and functional decline in older individuals","volume":"98","author":"Sohl","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0170","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s40520-015-0405-5","article-title":"Hypovitaminosis D is associated with a reduction in upper and lower limb muscle strength and physical performance in post-menopausal women: a retrospective study","volume":"27","author":"Iolascon","year":"2015","journal-title":"Aging Clin. Exp. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0175","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3390\/nu9040379","article-title":"Vitamin D status, muscle strength and physical performance decline in very old adults: a prospective study","volume":"9","author":"Granic","year":"2017","journal-title":"Nutrients."},{"key":"10.1016\/j.cellsig.2022.110355_bb0180","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1210\/jc.2013-1698","article-title":"Vitamin d status is associated with functional limitations and functional decline in older individuals","volume":"98","author":"Sohl","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0185","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.archger.2015.08.014","article-title":"Vitamin D status and physical function in older Finnish people: a one-year follow-up study","volume":"61","author":"Salminen","year":"2015","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/j.cellsig.2022.110355_bb0190","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1210\/jc.2014-3519","article-title":"Vitamin D and physical activity status: associations with five-year changes in body composition and muscle function in community-dwelling older adults","volume":"100","author":"Scott","year":"2015","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0195","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1111\/j.1532-5415.2011.03601.x","article-title":"Serum 25-hydroxyvitamin D and physical function in older adults: the cardiovascular health study all stars","volume":"59","author":"Houston","year":"2011","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.cellsig.2022.110355_bb0200","doi-asserted-by":"crossref","first-page":"5766","DOI":"10.1210\/jc.2003-030604","article-title":"Low Vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the longitudinal aging study Amsterdam","volume":"88","author":"Visser","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0205","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/gerona\/glx086","article-title":"Longitudinal associations between Vitamin D metabolites and sarcopenia in older Australian men: the Concord Health and Aging in Men Project","volume":"73","author":"Hirani","year":"2018","journal-title":"J. Gerontol. Ser. A."},{"key":"10.1016\/j.cellsig.2022.110355_bb0210","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1210\/jc.2006-1525","article-title":"Vitamin D status predicts physical performance and its decline in older persons","volume":"92","author":"Wicherts","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0215","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1007\/s12603-021-1645-z","article-title":"The relationship between sarcopenia and Vitamin D levels in adults of different ethnicities: findings from the West China Health and Aging Trend Study","volume":"25","author":"Luo","year":"2021","journal-title":"J. Nutr. Health Aging"},{"key":"10.1016\/j.cellsig.2022.110355_bb0220","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.23946","article-title":"Comparative analysis of the association between various serum vitamin D biomarkers and sarcopenia","volume":"35","author":"Yoo","year":"2021","journal-title":"J. Clin. Lab. Anal."},{"key":"10.1016\/j.cellsig.2022.110355_bb0225","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1507\/endocrj1954.26.Supplement_65","article-title":"Osteomalacic myopathy","volume":"26","author":"Yoshikawa","year":"1979","journal-title":"Endocrinol. Jpn."},{"key":"10.1016\/j.cellsig.2022.110355_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2020.111171","article-title":"Type-2 muscle fiber atrophy is associated with sarcopenia in elderly men with hip fracture","volume":"144","author":"Tanganelli","year":"2021","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0235","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.1210\/jc.2006-0510","article-title":"Vitamin D status in relation to one-year risk of recurrent falling in older men and women","volume":"91","author":"Snijder","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0240","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1359\/jbmr.080328","article-title":"Low serum 25-hydroxyvitamin D levels associated with falls among Japanese community-dwelling elderly","volume":"23","author":"Suzuki","year":"2008","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0245","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1007\/s12603-011-0345-5","article-title":"Vitamin D status in relation to postural stability in the elderly","volume":"16","author":"Boersma","year":"2012","journal-title":"J. Nutr. Health Aging"},{"key":"10.1016\/j.cellsig.2022.110355_bb0250","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1046\/j.1532-5415.2003.51510.x","article-title":"Serum Vitamin D and falls in older women in residential care in Australia","volume":"51","author":"Flicker","year":"2003","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.cellsig.2022.110355_bb0255","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1007\/s00198-015-3130-1","article-title":"Serum 25-hydroxyvitamin D level and risk of falls in Japanese community-dwelling elderly women: a 1-year follow-up study","volume":"26","author":"Shimizu","year":"2015","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.cellsig.2022.110355_bb0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12986-015-0029-y","article-title":"Does vitamin-D intake during resistance training improve the skeletal muscle hypertrophic and strength response in young and elderly men? - a randomized controlled trial","volume":"12","author":"Agergaard","year":"2015","journal-title":"Nutr Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0265","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1210\/jc.2013-2820","article-title":"A randomized study on the effect of Vitamin D3 supplementation on skeletal muscle morphology and Vitamin D receptor concentration in older women","volume":"98","author":"Ceglia","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0270","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s11657-018-0553-2","article-title":"Vitamin D supplementation and muscle strength in pre-sarcopenic elderly Lebanese people: a randomized controlled trial","volume":"14","author":"El Hajj","year":"2019","journal-title":"Arch. Osteoporos."},{"key":"10.1016\/j.cellsig.2022.110355_bb0275","first-page":"1","article-title":"The effect of high dose vitamin D3 on physical performance in frail older adults. A feasibility study","author":"Bray","year":"2018","journal-title":"J. Frailty Aging."},{"key":"10.1016\/j.cellsig.2022.110355_bb0280","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s00774-015-0695-x","article-title":"Eldecalcitol improves muscle strength and dynamic balance in postmenopausal women with osteoporosis: an open-label randomized controlled study","volume":"34","author":"Saito","year":"2016","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0285","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1111\/j.1532-5415.2010.03142.x","article-title":"A randomized controlled trial of the effects of Vitamin D on muscle strength and mobility in older women with Vitamin D insufficiency","volume":"58","author":"Zhu","year":"2010","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.cellsig.2022.110355_bb0290","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1007\/s00198-015-3151-9","article-title":"Effect of vitamin D supplementation alone on muscle function in postmenopausal women: a randomized, double-blind, placebo-controlled clinical trial","volume":"26","author":"Cangussu","year":"2015","journal-title":"Osteoporos. Int."},{"issue":"Suppl. 8","key":"10.1016\/j.cellsig.2022.110355_bb0295","first-page":"S26","article-title":"Effects of short-term Vitamin D supplementation on musculoskeletal and body balance for prevention of falling in postmenopausal women","volume":"98","author":"Anek","year":"2015","journal-title":"J. Med. Assoc. Thail."},{"key":"10.1016\/j.cellsig.2022.110355_bb0300","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1080\/02640414.2012.733822","article-title":"Assessment of vitamin D concentration in non-supplemented professional athletes and healthy adults during the winter months in the UK: implications for skeletal muscle function","volume":"31","author":"Close","year":"2013","journal-title":"J. Sports Sci."},{"key":"10.1016\/j.cellsig.2022.110355_bb0305","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1007\/s12325-017-0492-0","article-title":"Effectiveness of calcifediol in improving muscle function in post-menopausal women: a prospective cohort study","volume":"34","author":"Iolascon","year":"2017","journal-title":"Adv. Ther."},{"key":"10.1016\/j.cellsig.2022.110355_bb0310","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1159\/000235874","article-title":"Treatment of Vitamin D deficiency increases lower limb muscle strength in institutionalized older people independently of regular physical activity: a randomized double-blind controlled trial","volume":"54","author":"Moreira-Pfrimer","year":"2009","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0315","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/ajcn\/nqy290","article-title":"The effect of vitamin D supplementation on lower-extremity power and function in older adults: a randomized controlled trial","volume":"109","author":"Shea","year":"2019","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.cellsig.2022.110355_bb0320","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s00198-013-2473-8","article-title":"A parallel group double-blind RCT of vitamin D3 assessing physical function: is the biochemical response to treatment affected by overweight and obesity?","volume":"25","author":"Wood","year":"2014","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.cellsig.2022.110355_bb0325","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/BF03324819","article-title":"Muscle strength and mobility in vitamin D-insufficient female geriatric patients: a randomized controlled trial on vitamin D and calcium supplementation","volume":"22","author":"Janssen","year":"2010","journal-title":"Aging Clin. Exp. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0330","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1001\/jamainternmed.2015.3874","article-title":"Treatment of Vitamin D insufficiency in postmenopausal women","volume":"175","author":"Hansen","year":"2015","journal-title":"JAMA Intern. Med."},{"key":"10.1016\/j.cellsig.2022.110355_bb0335","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1046\/j.1532-5415.2003.51561.x","article-title":"Effects of Vitamin D supplementation on strength, physical function, and health perception in older, community-dwelling men","volume":"51","author":"Kenny","year":"2003","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.cellsig.2022.110355_bb0340","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/jbmr.524","article-title":"Effects of three-monthly oral 150,000 IU cholecalciferol supplementation on falls, mobility, and muscle strength in older postmenopausal women: a randomized controlled trial","volume":"27","author":"Glendenning","year":"2012","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0345","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/j.jada.2008.06.432","article-title":"Calcium, Vitamin D supplementation, and physical function in the Women\u2019s Health Initiative","volume":"108","author":"Brunner","year":"2008","journal-title":"J. Am. Diet. Assoc."},{"key":"10.1016\/j.cellsig.2022.110355_bb0350","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/jgs.14510","article-title":"Vitamin D and physical function in sedentary older men","volume":"65","author":"Levis","year":"2017","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.cellsig.2022.110355_bb0355","doi-asserted-by":"crossref","first-page":"5266","DOI":"10.1210\/jc.2010-2317","article-title":"Circulating 25-hydroxyvitamin D levels and frailty status in older women","volume":"95","author":"Ensrud","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0360","doi-asserted-by":"crossref","first-page":"227S","DOI":"10.1093\/jn\/129.1.227S","article-title":"Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in Normal and disease states","volume":"129","author":"Lecker","year":"1999","journal-title":"J. Nutr."},{"key":"10.1016\/j.cellsig.2022.110355_bb0365","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1126\/science.1065874","article-title":"Identification of ubiquitin ligases required for skeletal muscle atrophy","volume":"294","author":"Bodine","year":"2001","journal-title":"Science (80- )."},{"key":"10.1016\/j.cellsig.2022.110355_bb0370","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/nrc3829","article-title":"Cancer cachexia: understanding the molecular basis","volume":"14","author":"Argil\u00e9s","year":"2014","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.cellsig.2022.110355_bb0375","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S0092-8674(00)80595-4","article-title":"Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor","volume":"96","author":"Brunet","year":"1999","journal-title":"Cell."},{"key":"10.1016\/j.cellsig.2022.110355_bb0380","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2220\/biomedres.36.71","article-title":"1\u03b1,25(OH)2D3 downregulates gene expression levels of muscle ubiquitin ligases MAFbx and MuRF1 in human myotubes","volume":"36","author":"Hayakawa","year":"2015","journal-title":"Biomed. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0385","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jsbmb.2015.05.012","article-title":"Vitamin D treatment protects against and reverses oxidative stress induced muscle proteolysis","volume":"152","author":"Bhat","year":"2015","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0390","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3177\/jnsv.64.229","article-title":"Vitamin D attenuates FOXO1-target atrophy gene expression in C2C12 muscle cells","volume":"64","author":"Hirose","year":"2018","journal-title":"J. Nutr. Sci. Vitaminol. (Tokyo)"},{"key":"10.1016\/j.cellsig.2022.110355_bb0395","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2019\/6835341","article-title":"Vitamin D deficiency is associated with muscle atrophy and reduced mitochondrial function in patients with chronic low back pain","volume":"2019","author":"Dzik","year":"2019","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.cellsig.2022.110355_bb0400","doi-asserted-by":"crossref","first-page":"4018","DOI":"10.1210\/en.2013-1369","article-title":"Vitamin D deficiency-induced muscle wasting occurs through the ubiquitin proteasome pathway and is partially corrected by calcium in male rats","volume":"154","author":"Bhat","year":"2013","journal-title":"Endocrinology."},{"key":"10.1016\/j.cellsig.2022.110355_bb0405","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/jcsm.12497","article-title":"Vitamin D repletion ameliorates adipose tissue browning and muscle wasting in infantile nephropathic cystinosis-associated cachexia","volume":"11","author":"Cheung","year":"2020","journal-title":"J. Cachexia. Sarcopenia Muscle"},{"key":"10.1016\/j.cellsig.2022.110355_bb0410","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s13395-017-0121-2","article-title":"Inhibition of Stat3 signaling ameliorates atrophy of the soleus muscles in mice lacking the vitamin D receptor","volume":"7","author":"Gopinath","year":"2017","journal-title":"Skelet. Muscle"},{"key":"10.1016\/j.cellsig.2022.110355_bb0415","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.3390\/ijms19103092","article-title":"Nutritional modulation of AMPK-impact upon metabolic-inflammation","volume":"19","author":"Lyons","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cellsig.2022.110355_bb0420","doi-asserted-by":"crossref","first-page":"3558","DOI":"10.3390\/ijms19113558","article-title":"AMP-activated protein kinase as a key trigger for the disuse-induced skeletal muscle remodeling","volume":"19","author":"Vilchinskaya","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cellsig.2022.110355_bb0425","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.3390\/nu11112806","article-title":"Vitamin D ameliorates fat accumulation with AMPK\/SIRT1 activity in C2C12 skeletal muscle cells","volume":"11","author":"Chang","year":"2019","journal-title":"Nutrients."},{"key":"10.1016\/j.cellsig.2022.110355_bb0430","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.abb.2017.01.002","article-title":"Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1\/AMPK\/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice","volume":"615","author":"Manna","year":"2017","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.cellsig.2022.110355_bb0435","article-title":"Vitamin D alleviates skeletal muscle loss and insulin resistance by inducing vitamin D receptor expression and regulating the AMPK\/SIRT1 signaling pathway in mice. Food","volume":"42","author":"Li","year":"2022","journal-title":"Sci. Technol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0440","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/jcsm.12841","article-title":"Systemic ablation of vitamin D receptor leads to skeletal muscle glycogen storage disorder in mice","volume":"13","author":"Das","year":"2022","journal-title":"J. Cachexia. Sarcopenia Muscle"},{"key":"10.1016\/j.cellsig.2022.110355_bb0445","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1016\/j.biocel.2013.05.035","article-title":"Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia","volume":"45","author":"Yoshida","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0450","doi-asserted-by":"crossref","first-page":"649","DOI":"10.7326\/0003-4819-105-5-649","article-title":"Calcium-regulating hormones in essential hypertension","volume":"105","author":"Resnick","year":"1986","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.cellsig.2022.110355_bb0455","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1172\/JCI0215219","article-title":"1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system","volume":"110","author":"Li","year":"2002","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.cellsig.2022.110355_bb0460","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1113\/JP280652","article-title":"The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo","volume":"599","author":"Bass","year":"2021","journal-title":"J. Physiol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0465","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.chom.2009.08.004","article-title":"Vitamin D3 induces autophagy in human monocytes\/macrophages via cathelicidin","volume":"6","author":"Yuk","year":"2009","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.cellsig.2022.110355_bb0470","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.bbrc.2014.07.081","article-title":"1,25-Dyhydroxyvitamin D3 attenuates rotenone-induced neurotoxicity in SH-SY5Y cells through induction of autophagy","volume":"451","author":"Jang","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2022.110355_bb0475","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.793088","article-title":"Cellular senescence in sarcopenia: possible mechanisms and therapeutic potential","volume":"9","author":"He","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0480","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12848","article-title":"The bystander effect contributes to the accumulation of senescent cells in vivo","volume":"18","author":"da Silva","year":"2019","journal-title":"Aging Cell"},{"key":"10.1016\/j.cellsig.2022.110355_bb0485","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12951","article-title":"1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16\/p53-senescence signaling","volume":"18","author":"Chen","year":"2019","journal-title":"Aging Cell"},{"key":"10.1016\/j.cellsig.2022.110355_bb0490","first-page":"12638","article-title":"1,25-Dihydroxyvitamin D deficiency induces sarcopenia by inducing skeletal muscle cell senescence","volume":"13","author":"Yu","year":"2021","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0495","doi-asserted-by":"crossref","DOI":"10.1016\/j.mad.2021.111510","article-title":"New insights into molecular changes in skeletal muscle aging and disease: differential alternative splicing and senescence","volume":"197","author":"Solovyeva","year":"2021","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.cellsig.2022.110355_bb0500","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2020.601189","article-title":"Senescence is associated with elevated intracellular resting [Ca2 +] in mice skeletal muscle fibers. An in vivo study","volume":"11","author":"Mijares","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0505","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.bja.2018.07.008","article-title":"Malignant hyperthermia, environmental heat stress, and intracellular calcium dysregulation in a mouse model expressing the p.G2435R variant of RYR1","volume":"121","author":"Lopez","year":"2018","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.cellsig.2022.110355_bb0510","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1007\/s00223-015-0054-x","article-title":"Vitamin D receptor ablation and Vitamin D deficiency result in reduced grip strength, altered muscle fibers, and increased myostatin in mice","volume":"97","author":"Girgis","year":"2015","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.cellsig.2022.110355_bb0515","doi-asserted-by":"crossref","first-page":"E509","DOI":"10.1210\/jc.2012-3592","article-title":"Improving the Vitamin D status of Vitamin D deficient adults is associated with improved mitochondrial oxidative function in skeletal muscle","volume":"98","author":"Sinha","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0520","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3109\/07435800.2013.865210","article-title":"Effect of vitamin D supplementation on muscle energy phospho-metabolites: a 31 P magnetic resonance spectroscopy-based pilot study","volume":"39","author":"Rana","year":"2014","journal-title":"Endocr. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0525","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2019.105423","article-title":"Effects of vitamin D on primary human skeletal muscle cell proliferation, differentiation, protein synthesis and bioenergetics","volume":"193","author":"Romeu Montenegro","year":"2019","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0530","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jnutbio.2018.11.002","article-title":"Vitamin D produces a perilipin 2-dependent increase in mitochondrial function in C2C12 myotubes","volume":"65","author":"Schnell","year":"2019","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.cellsig.2022.110355_bb0535","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1074\/jbc.M115.684399","article-title":"1\u03b1,25-dihydroxyvitamin D 3 regulates mitochondrial oxygen consumption and dynamics in human skeletal muscle cells","volume":"291","author":"Ryan","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.cellsig.2022.110355_bb0540","article-title":"Diet-induced vitamin D deficiency results in reduced skeletal muscle mitochondrial respiration in C57BL\/6J mice","author":"Ashcroft","year":"2020","journal-title":"bioRxiv."},{"key":"10.1016\/j.cellsig.2022.110355_bb0545","doi-asserted-by":"crossref","first-page":"C536","DOI":"10.1152\/ajpcell.00568.2019","article-title":"The vitamin D receptor regulates mitochondrial function in C2C12 myoblasts","volume":"318","author":"Ashcroft","year":"2020","journal-title":"Am. J. Physiol. Physiol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0550","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.3390\/ijms19061672","article-title":"Vitamin D receptor is necessary for mitochondrial function and cell health","volume":"19","author":"Ricca","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cellsig.2022.110355_bb0555","doi-asserted-by":"crossref","first-page":"193","DOI":"10.33549\/physiolres.932993","article-title":"Excess of free fatty acids as a cause of metabolic dysfunction in skeletal muscle","author":"Tumova","year":"2016","journal-title":"Physiol. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0560","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2020.569904","article-title":"Exploring the impact of obesity on skeletal muscle function in older age","volume":"7","author":"Morgan","year":"2020","journal-title":"Front. Nutr."},{"key":"10.1016\/j.cellsig.2022.110355_bb0565","doi-asserted-by":"crossref","first-page":"e0221366","DOI":"10.1371\/journal.pone.0221366","article-title":"Aging- and obesity-related peri-muscular adipose tissue accelerates muscle atrophy. Kumar A, editor","volume":"14","author":"Zhu","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.cellsig.2022.110355_bb0570","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.archger.2017.01.014","article-title":"Relationship between quadriceps echo intensity and functional and morphological characteristics in older men and women","volume":"70","author":"Akima","year":"2017","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/j.cellsig.2022.110355_bb0575","first-page":"14977","article-title":"A meta-analysis of the relationship between vitamin D deficiency and obesity","volume":"8","author":"Yao","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.cellsig.2022.110355_bb0580","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1210\/jc.2009-2309","article-title":"Vitamin D status and its relation to muscle mass and muscle fat in young women","volume":"95","author":"Gilsanz","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0585","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s40520-018-0921-1","article-title":"The combination of vitamin D deficiency and overweight affects muscle mass and function in older post-menopausal women","volume":"30","author":"Gimigliano","year":"2018","journal-title":"Aging Clin. Exp. Res."},{"key":"10.1016\/j.cellsig.2022.110355_bb0590","first-page":"E916","article-title":"Molecular mechanism of 1,25-dihydroxyvitamin D 3 inhibition of adipogenesis in 3T3-L1 cells","volume":"290","author":"Kong","year":"2006","journal-title":"Am. J. Physiol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0595","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jsbmb.2017.10.010","article-title":"Vitamin D prevents lipid accumulation in murine muscle through regulation of PPAR\u03b3 and perilipin-2 expression","volume":"177","author":"Li","year":"2018","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0600","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1101\/gad.10.9.1096","article-title":"ADD1\/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism","volume":"10","author":"Kim","year":"1996","journal-title":"Genes Dev."},{"key":"10.1016\/j.cellsig.2022.110355_bb0605","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/cbf.2835","article-title":"New perspectives on the vitamin D binding protein","volume":"30","author":"Chun","year":"2012","journal-title":"Cell Biochem. Funct."},{"key":"10.1016\/j.cellsig.2022.110355_bb0610","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jsbmb.2013.09.012","article-title":"Vitamin D and DBP: the free hormone hypothesis revisited","volume":"144","author":"Chun","year":"2014","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0615","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1210\/en.2012-2245","article-title":"Evidence for a specific uptake and retention mechanism for 25-hydroxyvitamin D (25OHD) in skeletal muscle cells","volume":"154","author":"Abboud","year":"2013","journal-title":"Endocrinology."},{"key":"10.1016\/j.cellsig.2022.110355_bb0620","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.beem.2015.06.006","article-title":"Behind the scenes of vitamin D binding protein: more than vitamin D binding","volume":"29","author":"Delanghe","year":"2015","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2022.110355_bb0625","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1530\/JOE-20-0626","article-title":"Trophoblast uptake of DBP regulates intracellular actin and promotes matrix invasion","volume":"249","author":"Ganguly","year":"2021","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0630","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/0003-9861(82)90581-1","article-title":"Human serum binding protein for vitamin D and its metabolites (DBP): evidence that actin is the DBP binding component in human skeletal muscle","volume":"213","author":"Haddad","year":"1982","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.cellsig.2022.110355_bb0635","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.bbrc.2020.05.205","article-title":"Modified expression of vitamin D receptor and CYP27B1 in denervation-induced muscle atrophy","volume":"529","author":"Mori","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2022.110355_bb0640","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1056\/NEJMoa040933","article-title":"Myostatin mutation associated with gross muscle hypertrophy in a child","volume":"350","author":"Schuelke","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cellsig.2022.110355_bb0645","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1152\/japplphysiol.01139.2004","article-title":"ACTN3 genotype is associated with increases in muscle strength in response to resistance training in women","volume":"99","author":"Clarkson","year":"2005","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0650","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.3390\/nu13093109","article-title":"Association between polymorphisms in Vitamin D pathway-related genes, Vitamin D status, muscle mass and function: a systematic review","volume":"13","author":"Krasniqi","year":"2021","journal-title":"Nutrients."},{"key":"10.1016\/j.cellsig.2022.110355_bb0655","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cell.2019.02.048","article-title":"The missing diversity in human genetic studies","volume":"177","author":"Sirugo","year":"2019","journal-title":"Cell."},{"key":"10.1016\/j.cellsig.2022.110355_bb0660","first-page":"1","article-title":"Serum vitamin d and age-related muscle loss in afro-Caribbean men: the importance of age and diabetic status","author":"Hwang","year":"2018","journal-title":"J. Frailty Aging."},{"issue":"Suppl. 1","key":"10.1016\/j.cellsig.2022.110355_bb0665","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s003930070037","article-title":"Relationship between muscle strength and vitamin D metabolites: are there therapeutic possibilities in the elderly?","volume":"59","author":"Bischoff","year":"2000","journal-title":"Z. Rheumatol."},{"key":"10.1016\/j.cellsig.2022.110355_bb0670","doi-asserted-by":"crossref","first-page":"e0170665","DOI":"10.1371\/journal.pone.0170665","article-title":"25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression. Campbell M, editor","volume":"12","author":"Hassan-Smith","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.cellsig.2022.110355_bb0675","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13395-018-0166-x","article-title":"Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle","volume":"8","author":"Ahrens","year":"2018","journal-title":"Skelet. Muscle"},{"key":"10.1016\/j.cellsig.2022.110355_bb0680","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/sj.ki.5002163","article-title":"Klotho: an antiaging protein involved in mineral and vitamin D metabolism","volume":"71","author":"Torres","year":"2007","journal-title":"Kidney Int."}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656822001176?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656822001176?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T15:17:16Z","timestamp":1744903036000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0898656822001176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":136,"alternative-id":["S0898656822001176"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2022.110355","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Vitamin D\/Vitamin D receptor (VDR) axis in muscle atrophy and sarcopenia","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2022.110355","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"110355"}}