{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:52:04Z","timestamp":1793163124146,"version":"4.5.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004772","name":"Ningxia Hui Autonomous Region Natural Science Foundation","doi-asserted-by":"publisher","award":["2024AAC03107"],"award-info":[{"award-number":["2024AAC03107"]}],"id":[{"id":"10.13039\/501100004772","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82260025"],"award-info":[{"award-number":["82260025"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.cellsig.2024.111575","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T17:52:04Z","timestamp":1734717124000},"page":"111575","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Wnt5a alleviates the symptoms of PCOS by modulating PI3K\/AKT\/mTOR pathway-mediated autophagy in granulosa cells"],"prefix":"10.1016","volume":"127","author":[{"given":"Yabo","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fucheng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinrui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cellsig.2024.111575_bb0005","doi-asserted-by":"crossref","DOI":"10.1177\/20420188221127142","article-title":"Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and Meta-analysis of randomised controlled trials","volume":"13","author":"Abdalla","year":"2022","journal-title":"Ther. Adv. Endocrinol. Metab."},{"key":"10.1016\/j.cellsig.2024.111575_bb0010","article-title":"Broadening horizons: the role of Ferroptosis in polycystic ovary syndrome","volume":"15","author":"Wang","year":"2024","journal-title":"Front. Endocrinol."},{"issue":"6","key":"10.1016\/j.cellsig.2024.111575_bb0015","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1210\/endrev\/bnac001","article-title":"Deconstructing a syndrome: genomic insights into Pcos causal mechanisms and classification","volume":"43","author":"Dapas","year":"2022","journal-title":"Endocr. Rev."},{"issue":"6","key":"10.1016\/j.cellsig.2024.111575_bb0020","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.ando.2020.11.008","article-title":"Expression of Arid1a in polycystic ovary syndrome and its effect on the proliferation and apoptosis of ovarian granulosa cells","volume":"81","author":"Ji","year":"2020","journal-title":"Ann. Endocrinol."},{"issue":"16","key":"10.1016\/j.cellsig.2024.111575_bb0025","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.21037\/atm-21-4174","article-title":"Involvement of Ferroptosis in the granulosa cells proliferation of Pcos through the Circrhbg\/Mir-515\/Slc7a11 Axis","volume":"9","author":"Zhang","year":"2021","journal-title":"Ann. Transl. Med."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0030","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/s12884-024-06273-w","article-title":"Autophagy proteins and clinical data reveal the prognosis of polycystic ovary syndrome","volume":"24","author":"Wu","year":"2024","journal-title":"BMC Pregn. Childbirth"},{"key":"10.1016\/j.cellsig.2024.111575_bb0035","doi-asserted-by":"crossref","first-page":"3643","DOI":"10.2147\/DDDT.S317701","article-title":"Doxazosin attenuates liver fibrosis by inhibiting autophagy in hepatic stellate cells via activation of the Pi3k\/Akt\/Mtor signaling pathway","volume":"15","author":"Xiu","year":"2021","journal-title":"Drug Des. Devel. Ther."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0040","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s13048-024-01355-x","article-title":"Bushenhuoluo decoction improves polycystic ovary syndrome by regulating exosomal Mir-30a-5p\/ Socs3\/Mtor\/Nlrp3 signaling-mediated autophagy and pyroptosis","volume":"17","author":"Huang","year":"2024","journal-title":"J. Ovarian Res."},{"issue":"10","key":"10.1016\/j.cellsig.2024.111575_bb0045","doi-asserted-by":"crossref","first-page":"2706","DOI":"10.1080\/15548627.2021.1938914","article-title":"Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective","volume":"17","author":"Kumariya","year":"2021","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.cellsig.2024.111575_bb0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.repbio.2023.100763","article-title":"The effect of Sitagliptin combined with rosiglitazone on autophagy and inflammation in polycystic ovary syndrome by regulating Pi3k\/Akt\/Mtor and Tlr4\/Nf-\u039ab pathway","volume":"23","author":"Ren","year":"2023","journal-title":"Reprod. Biol."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0055","first-page":"73","article-title":"Melatonin ameliorates ovarian dysfunction by regulating autophagy in Pcos via the Pi3k-Akt pathway","volume":"162","author":"Xie","year":"2021","journal-title":"Reproduction"},{"key":"10.1016\/j.cellsig.2024.111575_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.112288","article-title":"Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the Pi3k\/Akt\/Mtor pathway through Lncmeg3","volume":"144","author":"Chen","year":"2021","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0065","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1210\/jc.2014-2419","article-title":"Up-regulated expression of Wnt5a increases inflammation and oxidative stress via Pi3k\/Akt\/Nf-\u039ab signaling in the granulosa cells of Pcos patients","volume":"100","author":"Zhao","year":"2015","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"4","key":"10.1016\/j.cellsig.2024.111575_bb0070","doi-asserted-by":"crossref","first-page":"R137","DOI":"10.1530\/REP-14-0685","article-title":"The role of Wnt signaling in adult ovarian folliculogenesis","volume":"150","author":"Hernandez Gifford","year":"2015","journal-title":"Reproduction"},{"key":"10.1016\/j.cellsig.2024.111575_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.jprot.2022.104772","article-title":"To explore the regulatory role of Wnt\/P53\/Caspase3 signal in mouse ovarian development based on Lfq proteomics","volume":"272","author":"Ma","year":"2023","journal-title":"J. Proteome"},{"issue":"6","key":"10.1016\/j.cellsig.2024.111575_bb0080","first-page":"7197","article-title":"Regulation of autophagy inhibition and inflammatory response in glioma by Wnt signaling pathway","volume":"14","author":"Wang","year":"2017","journal-title":"Oncol. Lett."},{"issue":"21","key":"10.1016\/j.cellsig.2024.111575_bb0085","doi-asserted-by":"crossref","first-page":"5873","DOI":"10.1158\/0008-5472.CAN-17-0907","article-title":"Atg5 mediates a positive feedback loop between Wnt signaling and autophagy in melanoma","volume":"77","author":"Ndoye","year":"2017","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0090","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1530\/REP-17-0499","article-title":"Autophagy is activated in the ovarian tissue of polycystic ovary syndrome","volume":"155","author":"Li","year":"2018","journal-title":"Reproduction"},{"issue":"12","key":"10.1016\/j.cellsig.2024.111575_bb0095","doi-asserted-by":"crossref","DOI":"10.3390\/biology11121761","article-title":"Cyproterone acetate mediates Ire1\u03b1 signaling pathway to alleviate pyroptosis of ovarian granulosa cells induced by hyperandrogen","volume":"11","author":"Zhang","year":"2022","journal-title":"Biology"},{"issue":"12","key":"10.1016\/j.cellsig.2024.111575_bb0100","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25126330","article-title":"A cross-sectional exploratory study of cardiovascular risk biomarkers in non-obese women with and without polycystic ovary syndrome: association with vitamin D","volume":"25","author":"Nandakumar","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.cellsig.2024.111575_bb0105","first-page":"336","article-title":"Polycystic ovary syndrome: a review of treatment options with a focus on pharmacological approaches","volume":"38","author":"Ndefo","year":"2013","journal-title":"P T."},{"issue":"17","key":"10.1016\/j.cellsig.2024.111575_bb0110","doi-asserted-by":"crossref","DOI":"10.3390\/jcm13175305","article-title":"Polycystic ovary syndrome: a comprehensive exploration of diagnosis experience in Saudi women","volume":"13","author":"Alqntash","year":"2024","journal-title":"J. Clin. Med."},{"issue":"2","key":"10.1016\/j.cellsig.2024.111575_bb0115","doi-asserted-by":"crossref","DOI":"10.1093\/hropen\/hoae013","article-title":"Ovarian Ferroptosis Induced by Androgen Is Involved in Pathogenesis of Pcos","volume":"2024","author":"Li","year":"2024","journal-title":"Hum Reprod Open"},{"issue":"16","key":"10.1016\/j.cellsig.2024.111575_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e36321","article-title":"Lncrna Pkd1p6 modulates ovarian granulosa cell survival of Hyperandrogenic polycystic ovary syndrome by targeting Mir-135b-5p and inhibiting Erk1\/2 signaling","volume":"10","author":"Zhou","year":"2024","journal-title":"Heliyon"},{"issue":"2","key":"10.1016\/j.cellsig.2024.111575_bb0125","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/s41574-020-00456-z","article-title":"The importance of metabolic dysfunction in polycystic ovary syndrome","volume":"17","author":"Visser","year":"2021","journal-title":"Nat. Rev. Endocrinol."},{"issue":"10","key":"10.1016\/j.cellsig.2024.111575_bb0130","article-title":"Polycystic ovary syndrome: a literature review with a focus on diagnosis, pathophysiology, and management","volume":"15","author":"Waghmare","year":"2023","journal-title":"Cureus"},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0135","doi-asserted-by":"crossref","DOI":"10.1080\/09513590.2023.2223724","article-title":"Chao Nang Qing prescription promotes granulosa cell apoptosis and autophagy by targeting Gata3","volume":"39","author":"Luo","year":"2023","journal-title":"Gynecol. Endocrinol."},{"issue":"6","key":"10.1016\/j.cellsig.2024.111575_bb0140","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1042\/CS20220408","article-title":"Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome","volume":"137","author":"Xing","year":"2023","journal-title":"Clin. Sci."},{"issue":"11","key":"10.1016\/j.cellsig.2024.111575_bb0145","doi-asserted-by":"crossref","DOI":"10.1177\/03000605211058376","article-title":"Chemerin regulates autophagy to participate in polycystic ovary syndrome","volume":"49","author":"Luo","year":"2021","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.cellsig.2024.111575_bb0150","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.1091147","article-title":"Insulin resistance, autophagy and apoptosis in patients with polycystic ovary syndrome: association with Pi3k signaling pathway","volume":"13","author":"Tong","year":"2022","journal-title":"Front. Endocrinol."},{"issue":"2","key":"10.1016\/j.cellsig.2024.111575_bb0155","doi-asserted-by":"crossref","DOI":"10.1080\/0886022X.2024.2369176","article-title":"Clinical impact of Wnt5a expression on persistence of acute kidney injury in patients with urosepsis","volume":"46","author":"Shin","year":"2024","journal-title":"Ren. Fail."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0160","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s10020-024-00862-3","article-title":"Wnt5a-mediated autophagy contributes to the epithelial-mesenchymal transition of human bronchial epithelial cells during asthma","volume":"30","author":"Liu","year":"2024","journal-title":"Mol. Med."},{"issue":"10","key":"10.1016\/j.cellsig.2024.111575_bb0165","doi-asserted-by":"crossref","DOI":"10.1172\/JCI159884","article-title":"Noncanonical Wnt5a controls the activation of latent Tgf-\u0392 to drive fibroblast activation and tissue fibrosis","volume":"134","author":"Trinh-Minh","year":"2024","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0170","doi-asserted-by":"crossref","DOI":"10.1080\/09513590.2023.2181637","article-title":"The ameliorative effect of Cangfu Daotan decoction on polycystic ovary syndrome of rodent model is associated with M6a methylation and Wnt\/\u0392-catenin pathway","volume":"39","author":"Zhang","year":"2023","journal-title":"Gynecol. Endocrinol."},{"issue":"4","key":"10.1016\/j.cellsig.2024.111575_bb0175","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1096\/fj.15-280313","article-title":"Wnt5a is required for Normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical Wnt signaling","volume":"30","author":"Abedini","year":"2016","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0180","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/s41419-020-03377-x","article-title":"Wnt5a promotes renal tubular inflammation in diabetic nephropathy by binding to Cd146 through noncanonical Wnt signaling","volume":"12","author":"Li","year":"2021","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0185","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12974-024-03068-w","article-title":"Wnt5a\/\u0392-catenin-mediated epithelial-mesenchymal transition: a key driver of subretinal fibrosis in Neovascular age-related macular degeneration","volume":"21","author":"Liu","year":"2024","journal-title":"J. Neuroinflammation"},{"issue":"3","key":"10.1016\/j.cellsig.2024.111575_bb0190","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1007\/s10753-022-01627-y","article-title":"Noncanonical Wnt5a\/Jnk signaling contributes to the development of D-gal\/Lps-induced acute liver failure","volume":"45","author":"Ji","year":"2022","journal-title":"Inflammation"},{"key":"10.1016\/j.cellsig.2024.111575_bb0195","doi-asserted-by":"crossref","first-page":"3285","DOI":"10.2147\/COPD.S334439","article-title":"Pm2.5 induces airway remodeling in chronic obstructive pulmonary diseases via the Wnt5a\/\u0392-catenin pathway","volume":"16","author":"Zou","year":"2021","journal-title":"Int. J. Chron. Obstruct. Pulmon. Dis."},{"key":"10.1016\/j.cellsig.2024.111575_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2021.111392","article-title":"Let-7e modulates the proliferation and the autophagy of human granulosa cells by suppressing P21 signaling pathway in polycystic ovary syndrome without Hyperandrogenism","volume":"535","author":"Li","year":"2021","journal-title":"Mol. Cell. Endocrinol."},{"issue":"8","key":"10.1016\/j.cellsig.2024.111575_bb0205","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1080\/09513590.2018.1540567","article-title":"The role of androgen in autophagy of granulosa cells from Pcos","volume":"35","author":"Li","year":"2019","journal-title":"Gynecol. Endocrinol."},{"issue":"12","key":"10.1016\/j.cellsig.2024.111575_bb0215","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.1016\/j.cellsig.2014.08.019","article-title":"The role of Pi3k\/Akt\/Mtor pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration","volume":"26","author":"Heras-Sandoval","year":"2014","journal-title":"Cell. Signal."},{"issue":"2","key":"10.1016\/j.cellsig.2024.111575_bb0220","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s00253-019-10257-8","article-title":"Targeting Pi3k\/Akt\/Mtor-mediated autophagy for tumor therapy","volume":"104","author":"Xu","year":"2020","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"6","key":"10.1016\/j.cellsig.2024.111575_bb0225","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/ca.23211","article-title":"The role of Mtor in ovarian neoplasms, polycystic ovary syndrome, and ovarian aging","volume":"31","author":"Liu","year":"2018","journal-title":"Clin. Anat."},{"issue":"5","key":"10.1016\/j.cellsig.2024.111575_bb0230","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1177\/1933719116667606","article-title":"Role of the Pi3k-Akt signaling pathway in the pathogenesis of polycystic ovary syndrome","volume":"24","author":"Li","year":"2017","journal-title":"Reprod. Sci."},{"issue":"6","key":"10.1016\/j.cellsig.2024.111575_bb0235","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3109\/07853890.2014.912836","article-title":"Pi3k\/Akt signaling pathway and cancer: an updated review","volume":"46","author":"Martini","year":"2014","journal-title":"Ann. Med."},{"issue":"4","key":"10.1016\/j.cellsig.2024.111575_bb0240","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1080\/19768354.2020.1790416","article-title":"Plumbagin inhibits proliferation and promotes apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inactivating Pi3k\/Akt\/Mtor pathway","volume":"24","author":"Cai","year":"2020","journal-title":"Anim. Cells Syst."},{"issue":"1","key":"10.1016\/j.cellsig.2024.111575_bb0245","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1530\/REP-13-0386","article-title":"Akt is involved in granulosa cell autophagy regulation via Mtor signaling during rat follicular development and atresia","volume":"147","author":"Choi","year":"2014","journal-title":"Reproduction"}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656824005515?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656824005515?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T04:33:29Z","timestamp":1762317209000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0898656824005515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":48,"alternative-id":["S0898656824005515"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2024.111575","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Wnt5a alleviates the symptoms of PCOS by modulating PI3K\/AKT\/mTOR pathway-mediated autophagy in granulosa cells","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2024.111575","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111575"}}