{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T21:54:19Z","timestamp":1793656459323,"version":"4.5.1"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T00:00:00Z","timestamp":1745625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82,170,550"],"award-info":[{"award-number":["82,170,550"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82,260,108"],"award-info":[{"award-number":["82,260,108"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82,160,107"],"award-info":[{"award-number":["82,160,107"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82,360,107"],"award-info":[{"award-number":["82,360,107"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202301AS070027"],"award-info":[{"award-number":["202301AS070027"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202301AT070091"],"award-info":[{"award-number":["202301AT070091"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202301AT070131"],"award-info":[{"award-number":["202301AT070131"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202201AY070001\\u2013086"],"award-info":[{"award-number":["202201AY070001\\u2013086"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["202201AY070001\\u2013048"],"award-info":[{"award-number":["202201AY070001\\u2013048"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018576","name":"Ten Thousand Talent Plans for Young Top-notch Talents of Yunnan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018576","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.cellsig.2025.111837","type":"journal-article","created":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T14:41:43Z","timestamp":1745678503000},"page":"111837","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Diminution of HSP75 disrupts intestinal epithelial barrier by inciting mPTP opening in ulcerative colitis"],"prefix":"10.1016","volume":"132","author":[{"given":"Hao","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huixian","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinglei","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunling","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junkun","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengrui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.cellsig.2025.111837_bb0005","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/s41395-018-0233-2","article-title":"Population density and risk of inflammatory bowel disease: a prospective Popula-tion-based study in 13 countries or regions in Asia-Pacific","volume":"114","author":"Ng","year":"2019","journal-title":"Am. J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.cellsig.2025.111837_bb0010","doi-asserted-by":"crossref","first-page":"135","DOI":"10.7861\/clinmed.2021-0080","article-title":"Ulcerative colitis: an update","volume":"21","author":"Segal","year":"2021","journal-title":"Clin. Med."},{"issue":"3","key":"10.1016\/j.cellsig.2025.111837_bb0015","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/nri3608","article-title":"Intestinal epithelial cells: regulators of barrier function and immune homeostasis","volume":"14","author":"Peterson","year":"2014","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cellsig.2025.111837_bb0020","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1146\/annurev.physiol.010908.163145","article-title":"Stem cells, self-renewal, and differentiation in the intestinal epithelium","volume":"71","author":"van der Flier","year":"2009","journal-title":"Annu. Rev. Physiol."},{"issue":"5","key":"10.1016\/j.cellsig.2025.111837_bb0025","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nrg1840","article-title":"Organizing cell renewal in the intestine: stem cells, signals and combinatorial control","volume":"7","author":"Crosnier","year":"2006","journal-title":"Nat. Rev. Genet."},{"issue":"9","key":"10.1016\/j.cellsig.2025.111837_bb0030","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1093\/ibd\/izac024","article-title":"Role of energy metabolism and mitochondrial function in inflammatory bowel disease","volume":"28","author":"\u00d6zsoy","year":"2022","journal-title":"Inflamm. Bowel Dis."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111837_bb0035","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.bbrc.2020.04.103","article-title":"Heat shock transcription factor 2 inhibits intestinal epithelial cell apoptosis through the Mito-chondrial pathway in ulcerative colitis","volume":"527","author":"Wang","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2025.111837_bb0040","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1146\/annurev-physiol-060821-083306","article-title":"Mitochondria and inflammatory bowel diseases: toward a stratified therapeutic intervention","volume":"84","author":"Ho","year":"2022","journal-title":"Annu. Rev. Physiol."},{"issue":"23","key":"10.1016\/j.cellsig.2025.111837_bb0045","doi-asserted-by":"crossref","first-page":"17124","DOI":"10.3390\/ijms242317124","article-title":"Role of mitochondria in inflammatory bowel dis-eases: a systematic review","volume":"24","author":"S\u00e1nchez-Quintero","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.cellsig.2025.111837_bb0050","first-page":"302","article-title":"The mitochondrial permeability transition pore and cancer: molecular mechanisms involved in cell death","volume":"17","author":"Bonora","year":"2014","journal-title":"Front. Oncol."},{"key":"10.1016\/j.cellsig.2025.111837_bb0055","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.yjmcc.2014.08.015","article-title":"Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury","volume":"78","author":"Morciano","year":"2015","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"6","key":"10.1016\/j.cellsig.2025.111837_bb0060","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.yjmcc.2009.02.021","article-title":"What is the mitochondrial permeability transition pore?","volume":"46","author":"Halestrap","year":"2009","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"4","key":"10.1016\/j.cellsig.2025.111837_bb0065","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-021-00433-y","article-title":"Molecular mechanisms and consequences of mitochondrial permeability transition","volume":"23","author":"Bonora","year":"2022","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.cellsig.2025.111837_bb0070","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ceca.2018.05.003","article-title":"The still uncertain identity of the channel-forming unit(s) of the mitochondrial permeability transition pore","volume":"73","author":"Baines","year":"2018","journal-title":"Cell Calcium"},{"issue":"1","key":"10.1016\/j.cellsig.2025.111837_bb0075","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s11010-020-03926-0","article-title":"Recent progress in the use of mitochondrial membrane permeability transition pore in mitochon-drial dysfunction-related disease therapies","volume":"476","author":"Cui","year":"2021","journal-title":"Mol. Cell. Biochem."},{"issue":"10","key":"10.1016\/j.cellsig.2025.111837_bb0080","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1007\/s00018-010-0286-x","article-title":"Bcl-2 family proteins and mitochondrial fission\/fusion dynamics","volume":"67","author":"Autret","year":"2010","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.cellsig.2025.111837_bb0085","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.869930","article-title":"Advances of heat shock family in ulcerative colitis","volume":"13","author":"Gong","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.cellsig.2025.111837_bb0090","doi-asserted-by":"crossref","DOI":"10.4081\/ejh.2011.e38","article-title":"Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy","volume":"55","author":"Tomasello","year":"2011","journal-title":"Eur. J. Histochem."},{"key":"10.1016\/j.cellsig.2025.111837_bb0095","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3389\/fimmu.2016.00171","article-title":"Heat shock protein-peptide and HSP-based immunotherapies for the treatment of cancer","volume":"7","author":"Shevtsov","year":"2016","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.cellsig.2025.111837_bb0100","doi-asserted-by":"crossref","first-page":"94","DOI":"10.2174\/1872213X10666161213163301","article-title":"Heat shock proteins: therapeutic perspectives in inflammatory disorders","volume":"10","author":"Khandia","year":"2017","journal-title":"Recent Patents Inflamm. Allergy Drug Discov."},{"issue":"2","key":"10.1016\/j.cellsig.2025.111837_bb0105","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/jcbfm.2008.125","article-title":"Overexpression of mitochondrial Hsp70\/Hsp75 in rat brain protects mitochondria, reduces oxidative stress, and protects from focal ischemia","volume":"29","author":"Xu","year":"2009","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.cellsig.2025.111837_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2021.152681","article-title":"Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin a","volume":"450","author":"Zhang","year":"2021","journal-title":"Toxicology"},{"key":"10.1016\/j.cellsig.2025.111837_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2022.109844","article-title":"Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication","volume":"354","author":"Wang","year":"2022","journal-title":"Chem. Biol. Interact."},{"issue":"4","key":"10.1016\/j.cellsig.2025.111837_bb0120","doi-asserted-by":"crossref","DOI":"10.26599\/FSHW.2024.9250181","article-title":"Ursolic acid inhibiting excessive reticulophagic flux contributes to alleviate ochratoxin A-induced endoplasmic reticulum stress- and mitochondrial-mediated apoptosis","volume":"14","author":"Deng","year":"2025","journal-title":"Food Sci. Human Wellness"},{"key":"10.1016\/j.cellsig.2025.111837_bb0125","article-title":"Ochratoxin a induces mitochondrial apoptosis and ferroptosis by inhibiting Sigma-1 receptor to disrupt redox and cholesterol homeostasis","author":"Yao","year":"2024","journal-title":"Food Sci. Human Wellness"},{"issue":"6","key":"10.1016\/j.cellsig.2025.111837_bb0130","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1136\/gutjnl-2014-308323","article-title":"TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signal-ling prevents DSS-induced colitis in mice","volume":"65","author":"Vlantis","year":"2016","journal-title":"Gut"},{"issue":"4","key":"10.1016\/j.cellsig.2025.111837_bb0135","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1053\/j.gastro.2020.06.049","article-title":"Intestinal epithelial expression of MHCII determines severity of chemical, T-cell-induced, and infectious colitis in mice","volume":"159","author":"Jamwal","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cellsig.2025.111837_bb0140","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.893426","article-title":"Heat shock transcription factor 2 promotes Mitophagy of intestinal epithelial cells through PARL\/PINK1\/Parkin pathway in ulcerative colitis","volume":"13","author":"Liang","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111837_bb0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2021.1902718","article-title":"Extracellular vesicles of Fusobacterium nucleatum compromise intestinal barrier through tar-geting RIPK1-mediated cell death pathway","volume":"13","author":"Liu","year":"2021","journal-title":"Gut Microbes"},{"issue":"4","key":"10.1016\/j.cellsig.2025.111837_bb0150","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1053\/j.gastro.2020.06.038","article-title":"IL1B increases intestinal tight junction permeability by up-regulation of MIR200C-3p, which degrades occludin mRNA","volume":"159","author":"Rawat","year":"2020","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.cellsig.2025.111837_bb0155","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s13045-021-01072-8","article-title":"CLK1\/SRSF5 pathway induces aberrant exon skipping of METTL14 and cyclin L2 and promotes growth and metastasis of pancreatic cancer","volume":"14","author":"Chen","year":"2021","journal-title":"J. Hematol. Oncol."},{"issue":"12","key":"10.1016\/j.cellsig.2025.111837_bb0160","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1111\/jgh.14696","article-title":"Association of TRAP1 with infliximab-induced mucosal healing in Crohn\u2019s disease","volume":"34","author":"Park","year":"2019","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"5","key":"10.1016\/j.cellsig.2025.111837_bb0165","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1038\/sj.jcbfm.9600600","article-title":"Overexpression of mitochondrial Hsp70\/Hsp75 protects astrocytes against is-chemic injury in vitro","volume":"28","author":"Voloboueva","year":"2008","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"11","key":"10.1016\/j.cellsig.2025.111837_bb0170","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.3390\/antiox10111829","article-title":"TRAP1 in oxidative stress and neurodegeneration","volume":"10","author":"Ramos Rego","year":"2021","journal-title":"Antioxidants (Basel)"},{"issue":"10","key":"10.1016\/j.cellsig.2025.111837_bb0175","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1038\/s41418-023-01218-w","article-title":"TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions","volume":"30","author":"Zhang","year":"2023","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.cellsig.2025.111837_bb0180","article-title":"Tumor necrosis factor receptor-associated protein 1 protects against mitochondrial injury by preventing high glucose-induced mPTP opening in diabetes","volume":"2020","author":"Liu","year":"2020","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111837_bb0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5483\/BMBRep.2012.45.1.1","article-title":"TRAP1 regulation of mitochondrial life or death decision in cancer cells and mitochondria-targeted TRAP1 in-hibitors","volume":"45","author":"Kang","year":"2012","journal-title":"BMB Rep."},{"key":"10.1016\/j.cellsig.2025.111837_bb0190","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s41038-019-0154-3","article-title":"Tumor necrosis factor receptor-associated protein 1 regulates hy-poxia-induced apoptosis through a mitochondria-dependent pathway mediated by cytochrome c oxidase subunit II","volume":"7","author":"Xiang","year":"2019","journal-title":"Burns Trauma"},{"issue":"8","key":"10.1016\/j.cellsig.2025.111837_bb0195","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1111\/j.1742-4658.2010.07615.x","article-title":"Mitochondrial chaperone tumour necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxic injury by regulating mitochondrial permeability transition pore opening","volume":"277","author":"Xiang","year":"2010","journal-title":"FEBS J."},{"key":"10.1016\/j.cellsig.2025.111837_bb0200","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.mito.2020.08.001","article-title":"Mitochondrial chaperone, TRAP1 modulates mitochondrial dynamics and promotes tumor metastasis","volume":"54","author":"Purushottam Dharaskar","year":"2020","journal-title":"Mitochondrion"},{"issue":"2","key":"10.1016\/j.cellsig.2025.111837_bb0205","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0014-5793(93)80273-W","article-title":"The mitochondrial permeability transition pore may comprise VDAC molecules. I. Binary structure and voltage dependence of the pore","volume":"330","author":"Szab\u00f3","year":"1993","journal-title":"FEBS Lett."},{"key":"10.1016\/j.cellsig.2025.111837_bb0210","doi-asserted-by":"crossref","first-page":"460","DOI":"10.3389\/fphys.2017.00460","article-title":"Mitochondrial VDAC1: a key gatekeeper as potential therapeutic target","volume":"8","author":"Camara","year":"2017","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111837_bb0215","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1042\/bj2680153","volume":"268","author":"Halestrap","year":"1990","journal-title":"Biochem. J."},{"issue":"12","key":"10.1016\/j.cellsig.2025.111837_bb0220","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1038\/s41418-022-01020-0","article-title":"The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel for-mation","volume":"29","author":"Cannino","year":"2022","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.cellsig.2025.111837_bb0225","doi-asserted-by":"crossref","first-page":"164","DOI":"10.3389\/fonc.2012.00164","article-title":"VDAC1: from structure to cancer therapy","volume":"2","author":"Shoshan-Barmatz","year":"2012","journal-title":"Front. Oncol."},{"issue":"5","key":"10.1016\/j.cellsig.2025.111837_bb0230","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1080\/07388551.2020.1756214","article-title":"VDAC and its interacting partners in plant and animal systems: an overview","volume":"40","author":"Kanwar","year":"2020","journal-title":"Crit. Rev. Biotechnol."},{"issue":"10","key":"10.1016\/j.cellsig.2025.111837_bb0235","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2013.379","article-title":"Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1","volume":"4","author":"Matassa","year":"2013","journal-title":"Cell Death Dis."},{"issue":"8","key":"10.1016\/j.cellsig.2025.111837_bb0240","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.neuint.2011.02.015","article-title":"Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum","volume":"58","author":"Takemoto","year":"2011","journal-title":"Neurochem. Int."},{"issue":"3","key":"10.1016\/j.cellsig.2025.111837_bb0245","doi-asserted-by":"crossref","first-page":"969","DOI":"10.3892\/ijo.2014.2530","article-title":"TRAP1 revisited: novel localizations and func-tions of a \u2018next-generation\u2019 biomarker","volume":"45","author":"Amoroso","year":"2014","journal-title":"Int. J. Oncol."},{"issue":"1\u20132","key":"10.1016\/j.cellsig.2025.111837_bb0250","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1023\/B:MCBI.0000009863.69249.d9","article-title":"VDAC and peripheral channelling complexes in health and disease","volume":"256-257","author":"Vyssokikh","year":"2004","journal-title":"Mol. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111837_bb0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mito.2008.10.003","article-title":"Putative partners in Bax mediated cytochrome-c release: ANT, CypD, VDAC or none of them?","volume":"9","author":"Kumarswamy","year":"2009","journal-title":"Mitochondrion"},{"issue":"2","key":"10.1016\/j.cellsig.2025.111837_bb0260","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.canlet.2013.01.045","article-title":"Inhibition of the mitochondrial Hsp90 chaperone network: a novel, efficient treatment strategy for cancer?","volume":"333","author":"Siegelin","year":"2013","journal-title":"Cancer Lett."}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656825002505?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656825002505?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T12:17:13Z","timestamp":1769689033000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0898656825002505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":52,"alternative-id":["S0898656825002505"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2025.111837","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diminution of HSP75 disrupts intestinal epithelial barrier by inciting mPTP opening in ulcerative colitis","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2025.111837","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111837"}}