{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:57:10Z","timestamp":1790186230456,"version":"4.1.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81603626"],"award-info":[{"award-number":["81603626"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020439","name":"Jiangsu Pharmaceutical Association","doi-asserted-by":"publisher","award":["J2024020"],"award-info":[{"award-number":["J2024020"]}],"id":[{"id":"10.13039\/100020439","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.cellsig.2025.111862","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T07:42:40Z","timestamp":1747122160000},"page":"111862","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["The regulatory mechanisms of mitophagy and oxidative stress in androgenetic alopecia"],"prefix":"10.1016","volume":"132","author":[{"given":"Dezhao","family":"Bi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunyao","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songmao","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.cellsig.2025.111862_bb0005","doi-asserted-by":"crossref","first-page":"85","DOI":"10.4103\/npmj.npmj_47_24","article-title":"Androgenetic alopecia: a review","volume":"31","author":"Oiwoh","year":"2024","journal-title":"Niger. Postgrad. Med. J."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0010","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1038\/s41467-017-01490-8","article-title":"GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk","volume":"8","author":"Pirastu","year":"2017","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.cellsig.2025.111862_bb0015","doi-asserted-by":"crossref","first-page":"263","DOI":"10.4103\/ijdvl.IJDVL_262_17","article-title":"Genetic and molecular aspects of androgenetic alopecia","volume":"84","author":"Martinez-Jacobo","year":"2018","journal-title":"Indian J. Dermatol. Venereol. Leprol."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0020","doi-asserted-by":"crossref","first-page":"119","DOI":"10.5114\/ada.2019.81685","article-title":"The impact of oxidative stress in androgenic alopecia in women","volume":"37","author":"Cwynar","year":"2020","journal-title":"Postepy Dermatol. Alergol."},{"key":"10.1016\/j.cellsig.2025.111862_bb0025","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.2147\/CCID.S462294","article-title":"Autophagy dysfunction: the kernel of hair loss?","volume":"17","author":"Jin","year":"2024","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"issue":"3","key":"10.1016\/j.cellsig.2025.111862_bb0030","doi-asserted-by":"crossref","first-page":"528","DOI":"10.5114\/ada.2021.107941","article-title":"Evaluation of selected parameters of oxidative stress in patients with androgenetic alopecia","volume":"38","author":"Cwynar","year":"2021","journal-title":"Postepy Dermatol. Alergol."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0035","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.tibs.2010.07.007","article-title":"Regulation of autophagy by ROS: physiology and pathology","volume":"36","author":"Scherz-Shouval","year":"2011","journal-title":"Trends Biochem. Sci."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0040","first-page":"3","article-title":"Mitochondrial electron transport chain, ROS generation and uncoupling (Review)","volume":"44","author":"Zhao","year":"2019","journal-title":"Int. J. Mol. Med."},{"issue":"3\u20134","key":"10.1016\/j.cellsig.2025.111862_bb0045","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0891-5849(00)00317-8","article-title":"Mitochondrial free radical generation, oxidative stress, and aging","volume":"29","author":"Cadenas","year":"2000","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0050","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/s41392-023-01503-7","article-title":"The mitophagy pathway and its implications in human diseases","volume":"8","author":"Wang","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jdermsci.2010.10.015","article-title":"Molecular basis of androgenetic alopecia: from androgen to paracrine mediators through dermal papilla","volume":"61","author":"Inui","year":"2011","journal-title":"J. Dermatol. Sci."},{"issue":"2","key":"10.1016\/j.cellsig.2025.111862_bb0060","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.jaad.2021.11.013","article-title":"The inflammatory component of androgenetic alopecia","volume":"86","author":"Heymann","year":"2022","journal-title":"J. Am. Acad. Dermatol."},{"issue":"465","key":"10.1016\/j.cellsig.2025.111862_bb0065","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.mce.2017.09.009","article-title":"Androgens and androgen receptor action in skin and hair follicles","volume":"15","author":"Ceruti","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"issue":"8","key":"10.1016\/j.cellsig.2025.111862_bb0070","doi-asserted-by":"crossref","DOI":"10.1002\/bies.201700029","article-title":"Oxidative stress management in the hair follicle: could targeting NRF2 counter age-related hair disorders and beyond?","volume":"39","author":"Jadkauskaite","year":"2017","journal-title":"Bioessays"},{"issue":"3","key":"10.1016\/j.cellsig.2025.111862_bb0075","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.det.2021.03.001","article-title":"Clinical patterns of hair loss in men: is dihydrotestosterone the only culprit?","volume":"39","author":"Kash","year":"2021","journal-title":"Dermatol. Clin."},{"issue":"6","key":"10.1016\/j.cellsig.2025.111862_bb0080","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1111\/jocd.13732","article-title":"Examination of androgenetic alopecia with serum biomarkers","volume":"20","author":"Bal\u0131k","year":"2021","journal-title":"J. Cosmet. Dermatol."},{"issue":"12","key":"10.1016\/j.cellsig.2025.111862_bb0085","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.18486","article-title":"Oxidative stress in hair follicle development and hair growth: Signalling pathways, intervening mechanisms and potential of natural antioxidants","volume":"28","author":"Du","year":"2024","journal-title":"J. Cell. Mol. Med."},{"issue":"5","key":"10.1016\/j.cellsig.2025.111862_bb0090","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1038\/jid.2015.28","article-title":"Oxidative stress-associated senescence in dermal papilla cells of men with androgenetic alopecia","volume":"135","author":"Upton","year":"2015","journal-title":"J. Invest. Dermatol."},{"issue":"2","key":"10.1016\/j.cellsig.2025.111862_bb0095","doi-asserted-by":"crossref","first-page":"426","DOI":"10.7150\/ijbs.76223","article-title":"Molecular mechanisms of mitochondrial quality control in ischemic cardiomyopathy","volume":"19","author":"Chang","year":"2023","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.cellsig.2025.111862_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155331","article-title":"Zishenhuoxue decoction-induced myocardial protection against ischemic injury through TMBIM6-VDAC1-mediated regulation of calcium homeostasis and mitochondrial quality surveillance","volume":"132","author":"Chang","year":"2024","journal-title":"Phytomedicine"},{"issue":"3","key":"10.1016\/j.cellsig.2025.111862_bb0105","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/jid.2014.475","article-title":"Mitochondrial function in murine skin epithelium is crucial for hair follicle morphogenesis and epithelial-mesenchymal interactions","volume":"135","author":"Kloepper","year":"2015","journal-title":"J. Invest. Dermatol."},{"issue":"261","key":"10.1016\/j.cellsig.2025.111862_bb0110","doi-asserted-by":"crossref","first-page":"ra8","DOI":"10.1126\/scisignal.2003638","article-title":"Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development","volume":"6","author":"Hamanaka","year":"2013","journal-title":"Sci. Signal."},{"issue":"12","key":"10.1016\/j.cellsig.2025.111862_bb0115","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1111\/j.1365-4632.2008.03783.x","article-title":"Hair growth stimulatory effect by a combination of 5-aminolevulinic acid and iron ion","volume":"47","author":"Morokuma","year":"2008","journal-title":"Int. J. Dermatol."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0120","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s11658-024-00536-2","article-title":"New insights into the role of mitochondrial metabolic dysregulation and immune infiltration in septic cardiomyopathy by integrated bioinformatics analysis and experimental validation","volume":"29","author":"Li","year":"2024","journal-title":"Cell. Mol. Biol. Lett."},{"issue":"6","key":"10.1016\/j.cellsig.2025.111862_bb0125","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1111\/exd.14536","article-title":"Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia","volume":"31","author":"Chew","year":"2022","journal-title":"Exp. Dermatol."},{"issue":"13","key":"10.1016\/j.cellsig.2025.111862_bb0130","doi-asserted-by":"crossref","first-page":"5145","DOI":"10.7150\/ijbs.96748","article-title":"Exploring the mechanism of Ferroptosis induction by Sappanone a in Cancer: insights into the mitochondrial dysfunction mediated by NRF2\/xCT\/GPX4 Axis","volume":"20","author":"Wang","year":"2024","journal-title":"Int. J. Biol. Sci."},{"issue":"12","key":"10.1016\/j.cellsig.2025.111862_bb0135","doi-asserted-by":"crossref","first-page":"4182","DOI":"10.1080\/15548627.2021.1907167","article-title":"The role of mitophagy in the regulation of mitochondrial energetic status in neurons","volume":"17","author":"Han","year":"2021","journal-title":"Autophagy"},{"issue":"4","key":"10.1016\/j.cellsig.2025.111862_bb0140","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s10456-024-09938-4","article-title":"Emerging insights into the pathogenesis and therapeutic strategies for vascular endothelial injury-associated diseases: focus on mitochondrial dysfunction","volume":"27","author":"Pang","year":"2024","journal-title":"Angiogenesis"},{"issue":"2019","key":"10.1016\/j.cellsig.2025.111862_bb0145","article-title":"Restoration of Autophagic flux rescues oxidative damage and mitochondrial dysfunction to protect against intervertebral disc degeneration","author":"Kang","year":"2019","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.cellsig.2025.111862_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154502","article-title":"\u00df-tubulin contributes to Tongyang Huoxue decoction-induced protection against hypoxia\/reoxygenation-induced injury of sinoatrial node cells through SIRT1-mediated regulation of mitochondrial quality surveillance","volume":"108","author":"Chang","year":"2023","journal-title":"Phytomedicine"},{"issue":"5","key":"10.1016\/j.cellsig.2025.111862_bb0155","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.1002\/ptr.8177","article-title":"Quercetin inhibits necroptosis in cardiomyocytes after ischemia-reperfusion via DNA-PKcs-SIRT5-orchestrated mitochondrial quality control","volume":"38","author":"Chang","year":"2024","journal-title":"Phytother. Res."},{"issue":"12","key":"10.1016\/j.cellsig.2025.111862_bb0160","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.1007\/s00204-023-03599-w","article-title":"Involvement of mitochondrial dynamics and mitophagy in diabetic endothelial dysfunction and cardiac microvascular injury","volume":"97","author":"Zhang","year":"2023","journal-title":"Arch. Toxicol."},{"issue":"7683","key":"10.1016\/j.cellsig.2025.111862_bb0165","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nature24645","article-title":"Structure of PINK1 in complex with its substrate ubiquitin","volume":"552","author":"Schubert","year":"2017","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.cellsig.2025.111862_bb0170","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1016\/j.cell.2019.05.026","article-title":"Autophagy-independent functions of the autophagy machinery","volume":"177","author":"Galluzzi","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.cellsig.2025.111862_bb0175","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/978-981-15-0602-4_3","article-title":"Regulation of autophagy by mTOR signaling pathway","volume":"1206","author":"Wang","year":"2019","journal-title":"Adv. Exp. Med. Biol."},{"issue":"Suppl. 2","key":"10.1016\/j.cellsig.2025.111862_bb0180","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1038\/sj.cdd.4401751","article-title":"Autophagy and signaling: their role in cell survival and cell death","volume":"12","author":"Codogno","year":"2005","journal-title":"Cell Death Differ."},{"issue":"1\u20132","key":"10.1016\/j.cellsig.2025.111862_bb0185","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.cell.2012.12.016","article-title":"Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy","volume":"152","author":"Kim","year":"2013","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.cellsig.2025.111862_bb0190","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1089\/ars.2013.5371","article-title":"An overview of autophagy: morphology, mechanism, and regulation","volume":"20","author":"Parzych","year":"2014","journal-title":"Antioxid. Redox Signal."},{"issue":"2","key":"10.1016\/j.cellsig.2025.111862_bb0195","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ceb.2010.01.001","article-title":"The Beclin 1 interactome","volume":"22","author":"He","year":"2010","journal-title":"Curr. Opin. Cell Biol."},{"issue":"24","key":"10.1016\/j.cellsig.2025.111862_bb0200","doi-asserted-by":"crossref","first-page":"4721","DOI":"10.1007\/s00018-015-2034-8","article-title":"Autophagy signal transduction by ATG proteins: from hierarchies to networks","volume":"72","author":"Wesselborg","year":"2015","journal-title":"Cell. Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0205","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1080\/15548627.2021.1909406","article-title":"How autophagy controls the intestinal epithelial barrier","volume":"18","author":"Foerster","year":"2022","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.cellsig.2025.111862_bb0210","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3390\/antiox10020302","article-title":"Redox regulation of PTEN by Peroxiredoxins","volume":"10","author":"Nguyen Huu","year":"2021","journal-title":"Antioxidants (Basel)"},{"issue":"8","key":"10.1016\/j.cellsig.2025.111862_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2021.119041","article-title":"Interactions between reactive oxygen species and autophagy: special issue: death mechanisms in cellular homeostasis","volume":"1868","author":"Redza-Dutordoir","year":"2021","journal-title":"Biochim. Biophys. Acta, Mol. Cell Res."},{"key":"10.1016\/j.cellsig.2025.111862_bb0220","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.semcancer.2019.05.012","article-title":"Role of the PI3K\/AKT\/mTOR signaling pathway in ovarian cancer: biological and therapeutic significance","volume":"59","author":"Ediriweera","year":"2019","journal-title":"Semin. Cancer Biol."},{"issue":"16","key":"10.1016\/j.cellsig.2025.111862_bb0225","doi-asserted-by":"crossref","first-page":"10892","DOI":"10.1074\/jbc.M800102200","article-title":"Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia","volume":"283","author":"Zhang","year":"2008","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.cellsig.2025.111862_bb0230","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1042\/BJ20111451","article-title":"Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling","volume":"441","author":"Lee","year":"2012","journal-title":"Biochem. J."},{"issue":"1","key":"10.1016\/j.cellsig.2025.111862_bb0235","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1038\/s41467-025-58150-5","article-title":"MCL-1 safeguards activated hair follicle stem cells to enable adult hair regeneration","volume":"16","author":"Chin","year":"2025","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.cellsig.2025.111862_bb0240","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/cdd.2010.191","article-title":"The Beclin 1 network regulates autophagy and apoptosis","volume":"18","author":"Kang","year":"2011","journal-title":"Cell Death Differ."},{"issue":"2","key":"10.1016\/j.cellsig.2025.111862_bb0245","doi-asserted-by":"crossref","first-page":"195","DOI":"10.4161\/auto.5278","article-title":"Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3","volume":"4","author":"Azad","year":"2008","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.cellsig.2025.111862_bb0250","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.jid.2016.08.035","article-title":"Oxidative damage control in a human (Mini-) organ: Nrf2 activation protects against oxidative stress-induced hair growth inhibition","volume":"137","author":"Haslam","year":"2017","journal-title":"J. Invest. Dermatol."},{"issue":"34","key":"10.1016\/j.cellsig.2025.111862_bb0255","doi-asserted-by":"crossref","first-page":"13561","DOI":"10.1073\/pnas.1121572109","article-title":"Keap1 degradation by autophagy for the maintenance of redox homeostasis","volume":"109","author":"Taguchi","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"3","key":"10.1016\/j.cellsig.2025.111862_bb0260","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/cdd.2014.150","article-title":"Oxidative stress and autophagy: the clash between damage and metabolic needs","volume":"22","author":"Filomeni","year":"2015","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.cellsig.2025.111862_bb0265","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.freeradbiomed.2022.07.014","article-title":"AMPK and NRF2: interactive players in the same team for cellular homeostasis?","volume":"190","author":"Petsouki","year":"2022","journal-title":"Free Radic. Biol. Med."},{"issue":"Pt B","key":"10.1016\/j.cellsig.2025.111862_bb0270","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.freeradbiomed.2015.06.006","article-title":"Molecular basis of the Keap1-Nrf2 system","volume":"88","author":"Suzuki","year":"2015","journal-title":"Free Radic. Biol. Med."},{"issue":"3","key":"10.1016\/j.cellsig.2025.111862_bb0275","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/ncb2021","article-title":"The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1","volume":"12","author":"Komatsu","year":"2010","journal-title":"Nat. Cell Biol."},{"issue":"11","key":"10.1016\/j.cellsig.2025.111862_bb0280","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1080\/15548627.2020.1712108","article-title":"SQSTM1\/p62 activates NFE2L2\/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity","volume":"16","author":"Lee","year":"2020","journal-title":"Autophagy"},{"issue":"7","key":"10.1016\/j.cellsig.2025.111862_bb0285","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.3390\/molecules27072176","article-title":"5-Bromo-3,4-dihydroxybenzaldehyde promotes hair growth through activation of Wnt\/\u03b2-catenin and autophagy pathways and inhibition of TGF-\u03b2 pathways in dermal papilla cells","volume":"27","author":"Kang","year":"2022","journal-title":"Molecules"},{"issue":"11","key":"10.1016\/j.cellsig.2025.111862_bb0290","doi-asserted-by":"crossref","first-page":"3307","DOI":"10.7150\/ijbs.80481","article-title":"The AR\/miR-221\/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia","volume":"19","author":"Li","year":"2023","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.cellsig.2025.111862_bb0295","doi-asserted-by":"crossref","first-page":"13875","DOI":"10.2147\/IJN.S477820","article-title":"Resveratrol-loaded versatile nanovesicle for alopecia therapy via comprehensive strategies","volume":"19","author":"Zhang","year":"2024","journal-title":"Int. J. Nanomedicine"},{"issue":"330","key":"10.1016\/j.cellsig.2025.111862_bb0300","article-title":"Ellagic acid inhibits dihydrotestosterone-induced ferroptosis and promotes hair regeneration by activating the wnt\/\u03b2-catenin signaling pathway","author":"Fu","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.cellsig.2025.111862_bb0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtemb.2023.127368","article-title":"Molybdenum nanoparticles as a potential topical medication for alopecia treatment through antioxidant pathways that differ from minoxidil","volume":"82","author":"Xiao","year":"2024","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"21","key":"10.1016\/j.cellsig.2025.111862_bb0310","doi-asserted-by":"crossref","first-page":"8592","DOI":"10.1021\/acs.nanolett.2c03119","article-title":"Machine learning guided discovery of superoxide dismutase Nanozymes for androgenetic alopecia","volume":"22","author":"Zhang","year":"2022","journal-title":"Nano Lett."},{"key":"10.1016\/j.cellsig.2025.111862_bb0315","first-page":"0433","article-title":"Mitophagy promotes hair regeneration by activating glutathione metabolism","volume":"7","author":"Wang","year":"2024","journal-title":"Research (Wash D C)"},{"issue":"12","key":"10.1016\/j.cellsig.2025.111862_bb0320","doi-asserted-by":"crossref","first-page":"3413","DOI":"10.1016\/j.celrep.2019.05.070","article-title":"Stimulation of hair growth by small molecules that activate autophagy","volume":"27","author":"Chai","year":"2019","journal-title":"Cell Rep."}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656825002773?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656825002773?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T12:18:03Z","timestamp":1769689083000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0898656825002773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":64,"alternative-id":["S0898656825002773"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2025.111862","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The regulatory mechanisms of mitophagy and oxidative stress in androgenetic alopecia","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2025.111862","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111862"}}