{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T06:57:00Z","timestamp":1781679420435,"version":"3.54.5"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017790","name":"EPIC-XS","doi-asserted-by":"publisher","award":["823839"],"award-info":[{"award-number":["823839"]}],"id":[{"id":"10.13039\/100017790","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011929","name":"Programa Operacional Tem\u00e1tico Factores de Competitividade","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011929","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.cellsig.2025.112132","type":"journal-article","created":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T13:02:36Z","timestamp":1757768556000},"page":"112132","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Identification of the PP1 interactome in human dental pulp: Insights for regenerative strategies"],"prefix":"10.1016","volume":"136","author":[{"given":"Anna","family":"Kobrock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Patr\u00edcio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1rbara","family":"Matos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Zarzuela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Howl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro S.","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarida","family":"Fardilha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cellsig.2025.112132_bb0005","series-title":"Diet and Oral Health: Factsheet on Oral Health and Sugars","author":"World Health Organization","year":"2018"},{"key":"10.1016\/j.cellsig.2025.112132_bb0010","series-title":"Dental Caries","author":"Rathee","year":"2019"},{"issue":"11","key":"10.1016\/j.cellsig.2025.112132_bb0015","first-page":"RA196","article-title":"Dental caries: from infection to prevention","volume":"13","author":"Islam","year":"2007","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.cellsig.2025.112132_bb0020","doi-asserted-by":"crossref","DOI":"10.3389\/fdmed.2021.651219","article-title":"Deciphering reparative processes in the inflamed dental pulp","volume":"2","author":"El Karim","year":"2021","journal-title":"Front. Dental Med."},{"issue":"2","key":"10.1016\/j.cellsig.2025.112132_bb0025","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/jor.1100160205","article-title":"In vitro differentiation of chick embryo bone marrow stromal cells into cartilaginous and bone-like tissues","volume":"16","author":"Martin","year":"1998","journal-title":"J. Orthop. Res."},{"issue":"7","key":"10.1016\/j.cellsig.2025.112132_bb0030","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.archoralbio.2010.12.008","article-title":"Comparative analysis of in vitro osteo\/odontogenic differentiation potential of human dental pulp stem cells (DPSCs) and stem cells from the apical papilla (SCAP)","volume":"56","author":"Bakopoulou","year":"2011","journal-title":"Arch. Oral Biol."},{"issue":"2","key":"10.1016\/j.cellsig.2025.112132_bb0035","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jdsr.2011.02.001","article-title":"Roles of dental pulp fibroblasts in the recognition of bacterium-related factors and subsequent development of pulpitis","volume":"47","author":"Nakanishi","year":"2011","journal-title":"Japan. Dental Sci. Rev."},{"issue":"4","key":"10.1016\/j.cellsig.2025.112132_bb0040","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1159\/000486592","article-title":"Biology explaining tooth repair and regeneration: a mini-review","volume":"64","author":"Balic","year":"2018","journal-title":"Gerontology"},{"issue":"3","key":"10.1016\/j.cellsig.2025.112132_bb0045","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/nrm2126","article-title":"Emerging roles of nuclear protein phosphatases","volume":"8","author":"Moorhead","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"2","key":"10.1016\/j.cellsig.2025.112132_bb0050","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1242\/jcs.115.2.241","article-title":"Protein phosphatase 1\u2013targeted in many directions","volume":"115","author":"Cohen","year":"2002","journal-title":"J. Cell Sci."},{"issue":"7","key":"10.1016\/j.cellsig.2025.112132_bb0055","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1136\/ard.2004.034090","article-title":"Phosphatase-1 and-2A inhibition modulates apoptosis in human osteoarthritis chondrocytes independently of nitric oxide production","volume":"64","author":"L\u00f3pez-Armada","year":"2005","journal-title":"Ann. Rheum. Dis."},{"issue":"40","key":"10.1016\/j.cellsig.2025.112132_bb0060","doi-asserted-by":"crossref","first-page":"10054","DOI":"10.1002\/anie.201204308","article-title":"Development of a peptide that selectively activates protein phosphatase-1 in living cells","volume":"51","author":"Chatterjee","year":"2012","journal-title":"Angew. Chem. Int. Ed."},{"issue":"3","key":"10.1016\/j.cellsig.2025.112132_bb0065","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.joen.2016.10.013","article-title":"Role of protein phosphatase 1 in angiogenesis and odontoblastic differentiation of human dental pulp cells","volume":"43","author":"Kim","year":"2017","journal-title":"J Endodont"},{"issue":"5","key":"10.1016\/j.cellsig.2025.112132_bb0070","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1002\/jlb.67.5.735","article-title":"Ceramide-mediated stimulation of inducible nitric oxide synthase (iNOS) and tumor necrosis factor (TNF) accumulation in murine macrophages requires tyrosine kinase activity","volume":"67","author":"Knapp","year":"2000","journal-title":"J. Leukoc. Biol."},{"issue":"7","key":"10.1016\/j.cellsig.2025.112132_bb0075","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.joen.2012.04.006","article-title":"The role of SIRT1 on angiogenic and odontogenic potential in human dental pulp cells","volume":"38","author":"Kim","year":"2012","journal-title":"J Endodont"},{"issue":"6","key":"10.1016\/j.cellsig.2025.112132_bb0080","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.joen.2015.01.038","article-title":"Effects of sodium tri-and hexametaphosphate on proliferation, differentiation, and angiogenic potential of human dental pulp cells","volume":"41","author":"Bae","year":"2015","journal-title":"J Endodont"},{"issue":"5","key":"10.1016\/j.cellsig.2025.112132_bb0085","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1600-0722.2005.00237.x","article-title":"Analysis of gene and protein expression in healthy and carious tooth pulp with cDNA microarray and two-dimensional gel electrophoresis","volume":"113","author":"P\u00e4\u00e4kk\u00f6nen","year":"2005","journal-title":"Eur. J. Oral Sci."},{"issue":"3","key":"10.1016\/j.cellsig.2025.112132_bb0090","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1590\/0103-6440202003167","article-title":"Comparative analysis of the proteomic profile of the dental pulp in different conditions. A pilot study","volume":"31","author":"Loureiro","year":"2020","journal-title":"Braz. Dent. J."},{"key":"10.1016\/j.cellsig.2025.112132_bb0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2105-15-293","article-title":"jvenn: an interactive Venn diagram viewer","volume":"15","author":"Bardou","year":"2014","journal-title":"BMC Bioinforma."},{"issue":"1","key":"10.1016\/j.cellsig.2025.112132_bb0100","first-page":"25","article-title":"Clinical and epidemiological behabour of acute dentoalveolar abscess in patients of the health area VII in Cienfuegos","volume":"13","author":"Mill\u00e1n","year":"2015","journal-title":"MediSur"},{"issue":"7","key":"10.1016\/j.cellsig.2025.112132_bb0105","first-page":"48","article-title":"Prevalencia de lesiones pulpares en pacientes tratados con endodoncia en la cl\u00ednica odontol\u00f3gica de la Escuela de Odontolog\u00eda de la Universidad del Valle","volume":"3","author":"Delgado","year":"2012","journal-title":"Rev. Colomb. Investig. en Odontol."},{"issue":"4","key":"10.1016\/j.cellsig.2025.112132_bb0110","first-page":"791","article-title":"Protein phosphatase 1\u03b1 is required for murine lung growth and morphogenesis","volume":"229","author":"Hormi-Carver","year":"2004","journal-title":"Develop. Dynam. Official Publ. Am. Assoc. Anatomists"},{"issue":"10","key":"10.1016\/j.cellsig.2025.112132_bb0115","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.2174\/156652412803833535","article-title":"Protein serine\/threonine phosphotase-1 is essential in governing normal development of vertebrate eye","volume":"12","author":"Liu","year":"2012","journal-title":"Curr. Mol. Med."},{"issue":"9","key":"10.1016\/j.cellsig.2025.112132_bb0120","doi-asserted-by":"crossref","first-page":"6619","DOI":"10.1074\/jbc.M606347200","article-title":"Phosphorylation of protein phosphatase 1 by cyclin-dependent protein kinase 5 during nerve growth factor-induced PC12 cell differentiation","volume":"282","author":"Li","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.cellsig.2025.112132_bb0125","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1242\/jcs.115.12.2465","article-title":"Involvement of protein phosphatase-1-mediated MARCKS translocation in myogenic differentiation of embryonic muscle cells","volume":"115","author":"Kim","year":"2002","journal-title":"J. Cell Sci."},{"issue":"1","key":"10.1016\/j.cellsig.2025.112132_bb0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.00013.2003","article-title":"Functional diversity of protein phosphatase-1, a cellular economizer and reset button","volume":"84","author":"Ceulemans","year":"2004","journal-title":"Physiol. Rev."},{"issue":"5","key":"10.1016\/j.cellsig.2025.112132_bb0135","first-page":"1383","article-title":"Analysis of isoform specific function of PP1 catalytic subunits in mammalian cells using siRNA","volume":"25","author":"Okada","year":"2004","journal-title":"Int. J. Oncol."},{"issue":"32","key":"10.1016\/j.cellsig.2025.112132_bb0140","doi-asserted-by":"crossref","first-page":"22193","DOI":"10.1074\/jbc.M803452200","article-title":"Identification of a protective role for protein phosphatase 1c\u03b31 against oxidative stress-induced vascular smooth muscle cell apoptosis","volume":"283","author":"Tchivilev","year":"2008","journal-title":"J. Biol. Chem."},{"issue":"21","key":"10.1016\/j.cellsig.2025.112132_bb0145","doi-asserted-by":"crossref","first-page":"14286","DOI":"10.1074\/jbc.M801377200","article-title":"Association of protein phosphatase 1\u03b31 with spinophilin suppresses phosphatase activity in a Parkinson disease model","volume":"283","author":"Brown","year":"2008","journal-title":"J. Biol. Chem."},{"issue":"10","key":"10.1016\/j.cellsig.2025.112132_bb0150","first-page":"e47623","article-title":"Significant expression levels of transgenic PPP1CC2 in testis and sperm are required to overcome the male infertility phenotype of Ppp1cc null mice","volume":"7","author":"Sinha","year":"2012"},{"issue":"12","key":"10.1016\/j.cellsig.2025.112132_bb0155","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1111\/j.1349-7006.1990.tb02690.x","article-title":"Identification of members of the protein phosphatase 1 gene family in the rat and enhanced expression of protein phosphatase 1\u03b1 gene in rat hepatocellular carcinomas","volume":"81","author":"Sasaki","year":"1990","journal-title":"Jpn. J. Cancer Res."},{"issue":"8","key":"10.1016\/j.cellsig.2025.112132_bb0160","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.tibs.2010.03.002","article-title":"The extended PP1 toolkit: designed to create specificity","volume":"35","author":"Bollen","year":"2010","journal-title":"Trends Biochem. Sci."},{"issue":"D1","key":"10.1016\/j.cellsig.2025.112132_bb0165","doi-asserted-by":"crossref","first-page":"D408","DOI":"10.1093\/nar\/gkw985","article-title":"HIPPIE v2. 0: enhancing meaningfulness and reliability of protein\u2013protein interaction networks","volume":"45","author":"Alanis-Lobato","year":"2016","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.cellsig.2025.112132_bb0170","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.trsl.2014.07.001","article-title":"Protein phosphatase 1 catalytic isoforms: specificity toward interacting proteins","volume":"164","author":"Korrodi-Greg\u00f3rio","year":"2014","journal-title":"Transl. Res."},{"issue":"2","key":"10.1016\/j.cellsig.2025.112132_bb0175","doi-asserted-by":"crossref","first-page":"188433","DOI":"10.1016\/j.bbcan.2020.188433","article-title":"Protein phosphatase 1 in tumorigenesis: is it worth a closer look?","volume":"1874","author":"Felgueiras","year":"2020","journal-title":"Biochimica et Biophysica Acta (BBA) Rev. Cancer"},{"issue":"1","key":"10.1016\/j.cellsig.2025.112132_bb0180","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.bbamcr.2018.07.019","article-title":"Functions and therapeutic potential of protein phosphatase 1: insights from mouse genetics","volume":"1866","author":"Ferreira","year":"2019","journal-title":"Biochimica Et Biophysica Acta (BBA)-Molecular Cell Res."},{"issue":"6","key":"10.1016\/j.cellsig.2025.112132_bb0185","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0049-3848(98)00122-4","article-title":"Development and disease in proteinase-deficient mice: role of the plasminogen, matrix metalloproteinase and coagulation system","volume":"91","author":"Carmeliet","year":"1998","journal-title":"Thromb. Res."},{"issue":"2","key":"10.1016\/j.cellsig.2025.112132_bb0190","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3109\/07388558809150542","article-title":"Plasminogen activation: biochemistry, physiology, and therapeutics","volume":"8","author":"Wun","year":"1988","journal-title":"Crit. Rev. Biotechnol."},{"issue":"3","key":"10.1016\/j.cellsig.2025.112132_bb0195","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00004770-200103000-00008","article-title":"Stimulation of plasminogen activator activity and matrix metalloproteinases of human dental pulp\u2013derived cells by tumor necrosis factor\u2013\u03b1","volume":"27","author":"Ueda","year":"2001","journal-title":"J Endodont"},{"issue":"10","key":"10.1016\/j.cellsig.2025.112132_bb0200","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1016\/j.bcp.2008.02.018","article-title":"Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp","volume":"75","author":"Kamio","year":"2008","journal-title":"Biochem. Pharmacol."},{"issue":"1","key":"10.1016\/j.cellsig.2025.112132_bb0205","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.joen.2017.09.002","article-title":"Dimethyloxalylglycine-embedded poly (\u03b5-caprolactone) fiber meshes promote odontoblastic differentiation of human dental pulp\u2013derived cells","volume":"44","author":"Yoo","year":"2018","journal-title":"J Endodont"},{"key":"10.1016\/j.cellsig.2025.112132_bb0210","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.gene.2018.04.048","article-title":"MYH9: structure, functions and role of non-muscle myosin IIA in human disease","volume":"664","author":"Pecci","year":"2018","journal-title":"Gene"},{"issue":"10","key":"10.1016\/j.cellsig.2025.112132_bb0215","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.joen.2020.07.008","article-title":"A decellularized matrix hydrogel derived from human dental pulp promotes dental pulp stem cell proliferation, migration, and induced multidirectional differentiation in vitro","volume":"46","author":"Li","year":"2020","journal-title":"J Endodont"},{"issue":"6","key":"10.1016\/j.cellsig.2025.112132_bb0220","doi-asserted-by":"crossref","first-page":"6689","DOI":"10.1096\/fj.201802224R","article-title":"Thy-1: more than a marker for mesenchymal stromal cells","volume":"33","author":"Saalbach","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.cellsig.2025.112132_bb0225","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3389\/fcell.2018.00127","article-title":"Thy-1 deficiency augments bone loss in obesity by affecting bone formation and resorption","volume":"6","author":"Picke","year":"2018","journal-title":"Front. Cell Develop. Biol."},{"issue":"12","key":"10.1016\/j.cellsig.2025.112132_bb0230","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1038\/ng.484","article-title":"Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans","volume":"41","author":"Alders","year":"2009","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.cellsig.2025.112132_bb0235","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1083\/jcb.152.6.1247","article-title":"Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation","volume":"152","author":"Troyanovsky","year":"2001","journal-title":"J. Cell Biol."},{"issue":"11","key":"10.1016\/j.cellsig.2025.112132_bb0240","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s00018-022-04591-w","article-title":"Fluid shear stress promotes periodontal ligament cells proliferation via p38-AMOT-YAP","volume":"79","author":"Shi","year":"2022","journal-title":"Cell. Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.cellsig.2025.112132_bb0245","doi-asserted-by":"crossref","first-page":"11283","DOI":"10.1038\/s41598-017-11641-y","article-title":"Copine-7 binds to the cell surface receptor, nucleolin, and regulates ciliogenesis and Dspp expression during odontoblast differentiation","volume":"7","author":"Seo","year":"2017","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.cellsig.2025.112132_bb0250","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/jcmm.12266","article-title":"TGF-\u03b2 cascade regulation by PPP 1 and its interactors\u2013impact on prostate cancer development and therapy","volume":"18","author":"Korrodi-Greg\u00f3rio","year":"2014","journal-title":"J. Cell. Mol. Med."},{"issue":"1","key":"10.1016\/j.cellsig.2025.112132_bb0255","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1146\/annurev.biochem.67.1.753","article-title":"TGF-\u03b2 signal transduction","volume":"67","author":"Massague","year":"1998","journal-title":"Annu. Rev. Biochem."},{"issue":"6","key":"10.1016\/j.cellsig.2025.112132_bb0260","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1080\/03008200802325060","article-title":"Transgenic overexpression of gremlin results in developmental defects in enamel and dentin in mice","volume":"49","author":"Nagatomo","year":"2008","journal-title":"Connect. Tissue Res."},{"issue":"1","key":"10.1016\/j.cellsig.2025.112132_bb0265","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0167-4838(97)00188-X","article-title":"cDNA cloning of bovine thrombospondin 1 and its expression in odontoblasts and predentin","volume":"1382","author":"Ueno","year":"1998","journal-title":"Biochimica et Biophysica Acta (BBA) Protein Struct. Mol. Enzymol."},{"issue":"3","key":"10.1016\/j.cellsig.2025.112132_bb0270","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/s11626-007-9022-8","article-title":"Matrix and TGF- \u03b2 -related gene expression during human dental pulp stem cell (DPSC) mineralization","volume":"43","author":"Liu","year":"2007","journal-title":"Vitr Cell Dev Biol."},{"issue":"2","key":"10.1016\/j.cellsig.2025.112132_bb0275","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1523-1755.2004.00395.x","article-title":"Thrombospondin-1 is a major activator of TGF- b in fibrotic renal disease in the rat in vivo","volume":"65","author":"Christoph","year":"2004","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.cellsig.2025.112132_bb0280","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0955-0674(00)00143-5","article-title":"The functions of thrombospondin-1 and -2","volume":"12","author":"Lawler","year":"2000","journal-title":"Curr. Opin. Cell Biol."},{"issue":"2","key":"10.1016\/j.cellsig.2025.112132_bb0285","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0300-5712(99)00047-0","article-title":"Designing new treatment strategies in vital pulp therapy","volume":"28","author":"Tziafas","year":"2000","journal-title":"J. Dent."},{"issue":"1","key":"10.1016\/j.cellsig.2025.112132_bb0290","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1600-0722.2007.00420.x","article-title":"Transforming growth factor-\u03b21 up-regulates the expression of nerve growth factor through mitogen-activated protein kinase signaling pathways in dental pulp cells","volume":"115","author":"Yongchaitrakul","year":"2007","journal-title":"Eur. J. Oral Sci."},{"issue":"145","key":"10.1016\/j.cellsig.2025.112132_bb0295","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jprot.2016.04.022","article-title":"Proteomic analysis of human tooth pulp proteomes\u2013comparison of caries-resistant and caries-susceptible persons","author":"J\u00e1gr","year":"2016","journal-title":"J. Proteome"},{"key":"10.1016\/j.cellsig.2025.112132_bb0300","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s11010-011-1065-1","article-title":"Extracellular 14-3-3 from human lung epithelial cells enhances MMP-1 expression","volume":"360","author":"Asdaghi","year":"2012","journal-title":"Mol. Cell. Biochem."},{"issue":"7","key":"10.1016\/j.cellsig.2025.112132_bb0305","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1128\/MCB.23.7.2264-2276.2003","article-title":"The \u0394Np63\u03b1 phosphoprotein binds the p21 and 14-3-3\u03c3 promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations","volume":"23","author":"Westfall","year":"2003","journal-title":"Mol. Cell. Biol."},{"issue":"18","key":"10.1016\/j.cellsig.2025.112132_bb0310","doi-asserted-by":"crossref","first-page":"3187","DOI":"10.1016\/j.yexcr.2009.08.002","article-title":"\u03b13\u03b21 integrin promotes cell survival via multiple interactions between 14-3-3 isoforms and proapoptotic proteins","volume":"315","author":"Oh","year":"2009","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.cellsig.2025.112132_bb0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12953-015-0089-y","article-title":"Analysis of protein expression in periodontal pocket tissue: a preliminary study","volume":"13","author":"Monari","year":"2015","journal-title":"Proteome Sci."},{"key":"10.1016\/j.cellsig.2025.112132_bb0320","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.bbrc.2021.01.057","article-title":"ACTG1 regulates intervertebral disc degeneration via the NF-\u03baB-p65 and Akt pathways","volume":"545","author":"Wu","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.cellsig.2025.112132_bb0325","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.993478","article-title":"Atlas of human dental pulp cells at multiple spatial and temporal levels based on single-cell sequencing analysis","volume":"13","author":"Ren","year":"2022","journal-title":"Front. Physiol."},{"key":"10.1016\/j.cellsig.2025.112132_bb0330","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s00439-016-1683-5","article-title":"The hnRNP family: insights into their role in health and disease","volume":"135","author":"Geuens","year":"2016","journal-title":"Hum. Genet."},{"issue":"9","key":"10.1016\/j.cellsig.2025.112132_bb0335","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1634\/stemcells.2004-0372","article-title":"Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation","volume":"23","author":"Foster","year":"2005","journal-title":"Stem Cells"}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656825005479?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656825005479?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T06:38:03Z","timestamp":1781678283000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0898656825005479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":67,"alternative-id":["S0898656825005479"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2025.112132","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of the PP1 interactome in human dental pulp: Insights for regenerative strategies","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2025.112132","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"112132"}}