{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T06:51:57Z","timestamp":1785912717679,"version":"3.56.0"},"reference-count":152,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cellular Signalling"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.cellsig.2026.112696","type":"journal-article","created":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T15:45:37Z","timestamp":1782575137000},"page":"112696","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Post-translational modifications in triple-negative breast cancer: research status and translation challenges"],"prefix":"10.1016","volume":"146","author":[{"given":"Jia-Mei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.cellsig.2026.112696_bb0005","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.ccell.2019.02.001","article-title":"Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies","volume":"35","author":"Jiang","year":"2019","journal-title":"Cancer Cell"},{"issue":"2","key":"10.1016\/j.cellsig.2026.112696_bb0010","doi-asserted-by":"crossref","first-page":"509","DOI":"10.7150\/thno.101685","article-title":"Detecting metastatic potential of cancer through longitudinal vasculature imaging of biomaterial scaffold using non-invasive in vivo photoacoustic microscopy and optical coherence tomography","volume":"15","author":"Xu","year":"2025","journal-title":"Theranostics"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0015","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/ptr.8376","article-title":"Phytochemicals as novel therapeutics for triple-negative breast cancer: a comprehensive review of current knowledge","volume":"39","author":"Bhutta","year":"2025","journal-title":"Phytother. Res."},{"key":"10.1016\/j.cellsig.2026.112696_bb0020","doi-asserted-by":"crossref","DOI":"10.2174\/0118761429263063231204095516","article-title":"Anticancer properties of baicalin against breast cancer and other gynecological cancers: therapeutic opportunities based on underlying mechanisms","volume":"17","author":"Pourhanifeh","year":"2024","journal-title":"Curr. Mol. Pharmacol."},{"key":"10.1016\/j.cellsig.2026.112696_bb0025","article-title":"Deregulated MicroRNAs involved in p53 signaling pathway in breast cancer with focus on triple-negative breast cancer","volume":"17","author":"Naeimzadeh","year":"2024","journal-title":"Curr. Mol. Pharmacol."},{"issue":"Pt 2","key":"10.1016\/j.cellsig.2026.112696_bb0030","article-title":"PiR-hsa-35410 promotes triple-negative breast cancer progression via enhancing PFKL mediated glycolysis","volume":"242","author":"Zhang","year":"2025","journal-title":"Biochem. Pharmacol."},{"issue":"3","key":"10.1016\/j.cellsig.2026.112696_bb0035","first-page":"241","article-title":"MiR-634 decreases the radioresistance of human breast cancer cells by targeting STAT3","volume":"35","author":"Yang","year":"2020","journal-title":"Cancer Biother. Radiopharm."},{"issue":"4","key":"10.1016\/j.cellsig.2026.112696_bb0040","doi-asserted-by":"crossref","first-page":"470","DOI":"10.2174\/1871520622666220817125817","article-title":"Isoproterenol-induced upregulation of HPSE accelerates triple-negative breast cancer cell proliferation and migration through enhancing the transcriptional activity of HIF-1\u03b1","volume":"23","author":"Qiu","year":"2023","journal-title":"Anti Cancer Agents Med. Chem."},{"issue":"6","key":"10.1016\/j.cellsig.2026.112696_bb0045","doi-asserted-by":"crossref","first-page":"458","DOI":"10.2174\/0113892029371937250918105052","article-title":"The bacterial role in the progression of breast cancer through mechanism of gene action: future prospects with existing studies","volume":"26","author":"Nawaz","year":"2025","journal-title":"Curr. Genomics"},{"issue":"6","key":"10.1016\/j.cellsig.2026.112696_bb0050","doi-asserted-by":"crossref","first-page":"621","DOI":"10.2174\/0113892029374158251030064845","article-title":"Analysis of endoplasmic reticulum stress-associated proteins as prognostic markers in breast cancer","volume":"26","author":"Shreya","year":"2025","journal-title":"Curr. Genomics"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0055","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s13058-022-01519-x","article-title":"Clinical significance of HER2-low expression in early breast cancer: a nationwide study from the Korean breast cancer society","volume":"24","author":"Won","year":"2022","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.cellsig.2026.112696_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156869","article-title":"Genkwanin impairs triple-negative breast cancer aggressiveness and metastasis by targeting lysine demethylase 4C","volume":"143","author":"Xu","year":"2025","journal-title":"Phytomedicine"},{"issue":"11\u201312","key":"10.1016\/j.cellsig.2026.112696_bb0065","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s10495-022-01763-8","article-title":"DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients","volume":"27","author":"Vasiyani","year":"2022","journal-title":"Apoptosis"},{"issue":"7","key":"10.1016\/j.cellsig.2026.112696_bb0070","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/s41388-021-02136-2","article-title":"Novel function of THEMIS2 in the enhancement of cancer stemness and chemoresistance by releasing PTP1B from MET","volume":"41","author":"Huang","year":"2022","journal-title":"Oncogene"},{"issue":"19","key":"10.1016\/j.cellsig.2026.112696_bb0075","doi-asserted-by":"crossref","DOI":"10.3390\/cells12192407","article-title":"An overview of the role of furin in type 2 diabetes","volume":"12","author":"Marafie","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.cellsig.2026.112696_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2022.101097","article-title":"Pathological implication of protein post-translational modifications in cancer","volume":"86","author":"Pan","year":"2022","journal-title":"Mol. Asp. Med."},{"issue":"9","key":"10.1016\/j.cellsig.2026.112696_bb0085","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1002\/cac2.70044","article-title":"Ubiquitination in cancer: mechanisms and therapeutic opportunities","volume":"45","author":"Zhu","year":"2025","journal-title":"Cancer Commun. (Lond.)"},{"key":"10.1016\/j.cellsig.2026.112696_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.216758","article-title":"Unleashing the power of immune checkpoints: Post-translational modification of novel molecules and clinical applications","volume":"588","author":"Wang","year":"2024","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0095","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/s41420-025-02410-2","article-title":"Functions and mechanisms of non-histone post-translational modifications in cancer progression","volume":"11","author":"Li","year":"2025","journal-title":"Cell Death Discov."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0100","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1186\/s12943-025-02397-5","article-title":"Post-translational modifications of cancer immune checkpoints: mechanisms and therapeutic strategies","volume":"24","author":"Jia","year":"2025","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.cellsig.2026.112696_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.216614","article-title":"Interplay between posttranslational modifications and liquid\u2013liquid phase separation in tumors","volume":"584","author":"Yan","year":"2024","journal-title":"Cancer Lett."},{"issue":"10","key":"10.1016\/j.cellsig.2026.112696_bb0110","first-page":"4683","article-title":"Role of succinylation modification in thyroid cancer and breast cancer","volume":"11","author":"Mu","year":"2021","journal-title":"Am. J. Cancer Res."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0115","doi-asserted-by":"crossref","first-page":"63","DOI":"10.7150\/ijbs.101861","article-title":"Targeting protein modification: a new direction for immunotherapy of pancreatic cancer","volume":"21","author":"Ge","year":"2025","journal-title":"Int. J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0120","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12929-023-00909-3","article-title":"E26 transformation-specific transcription variant 5 in development and cancer: modification, regulation and function","volume":"30","author":"Wei","year":"2023","journal-title":"J. Biomed. Sci."},{"issue":"2","key":"10.1016\/j.cellsig.2026.112696_bb0125","first-page":"321","article-title":"Phosphoproteomics in the diagnosis and treatment of triple-negative breast cancer: a review","volume":"40","author":"Shi","year":"2024","journal-title":"Sheng Wu Gong Cheng Xue Bao"},{"issue":"2","key":"10.1016\/j.cellsig.2026.112696_bb0130","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1074\/mcp.RA119.001800","article-title":"Combined EGFR and ROCK inhibition in triple-negative breast cancer leads to cell death via impaired autophagic flux","volume":"19","author":"Rontogianni","year":"2020","journal-title":"Mol. Cell. Proteomics"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0135","article-title":"Mapping nanoscale-to-single-cell phosphoproteomic landscape by Chip-DIA","volume":"12","author":"Muneer","year":"2025","journal-title":"Adv. Sci. (Weinh)"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0140","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/s41531-024-00830-y","article-title":"Novel tools to quantify total, phospho-Ser129 and aggregated alpha-synuclein in the mouse brain","volume":"10","author":"Trist","year":"2024","journal-title":"NPJ Parkinsons Dis."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0145","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1038\/s41467-018-05742-z","article-title":"In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer","volume":"9","author":"Zagorac","year":"2018","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.cellsig.2026.112696_bb0150","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.201902073","article-title":"Phosphorylation of PKCdelta by FER tips the balance from EGFR degradation to recycling","volume":"220","author":"Lonic","year":"2021","journal-title":"J. Cell Biol."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0155","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/s13578-024-01249-x","article-title":"Tumour-specific phosphorylation of serine 419 drives alpha-enolase (ENO1) nuclear export in triple negative breast cancer progression","volume":"14","author":"Marshall","year":"2024","journal-title":"Cell Biosci."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0160","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s12964-024-01487-z","article-title":"Superbinder based phosphoproteomic landscape revealed PRKCD_pY313 mediates the activation of src and p38 MAPK to promote TNBC progression","volume":"22","author":"Deng","year":"2024","journal-title":"Cell Commun. Signal"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0165","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1186\/s12967-024-05946-6","article-title":"LRPPRC confers enhanced oxidative phosphorylation metabolism in triple-negative breast cancer and represents a therapeutic target","volume":"23","author":"Xue","year":"2025","journal-title":"J. Transl. Med."},{"issue":"16","key":"10.1016\/j.cellsig.2026.112696_bb0170","doi-asserted-by":"crossref","first-page":"4346","DOI":"10.1158\/0008-5472.CAN-20-4190","article-title":"Targeting pyruvate kinase m2 phosphorylation reverses aggressive cancer phenotypes","volume":"81","author":"Apostolidi","year":"2021","journal-title":"Cancer Res."},{"issue":"9","key":"10.1016\/j.cellsig.2026.112696_bb0175","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1038\/s41416-025-03163-6","article-title":"CDCP1\/mitochondrial src axis increases electron transport chain function to promote metastasis in triple-negative breast cancer","volume":"133","author":"Woytash","year":"2025","journal-title":"Br. J. Cancer"},{"issue":"12","key":"10.1016\/j.cellsig.2026.112696_bb0180","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-005668","article-title":"Modification of PLAC8 by UFM1 affects tumorous proliferation and immune response by impacting PD-L1 levels in triple-negative breast cancer","volume":"10","author":"Mao","year":"2022","journal-title":"J. Immunother. Cancer"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0185","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1186\/s12905-025-03896-9","article-title":"Correlations of phosphorylated nrf2 with responses to neoadjuvant chemotherapy in patients with triple-negative breast cancer","volume":"25","author":"Yu","year":"2025","journal-title":"BMC Womens Health"},{"issue":"10","key":"10.1016\/j.cellsig.2026.112696_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2025.116365","article-title":"DUSP14 suppresses ferroptosis and promotes tumor progression of triple-negative breast cancer","volume":"44","author":"Cao","year":"2025","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0195","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s13046-025-03343-5","article-title":"NONO interacts with nuclear PKM2 and directs histone h3 phosphorylation to promote triple-negative breast cancer metastasis","volume":"44","author":"Li","year":"2025","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0200","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13058-025-02086-7","article-title":"Erdafitinib inhibits the tumorigenicity of MDA-MB-231 triple-negative breast cancer cells by inducing TRIM25\/ubiquitin-dependent degradation of FGFR4","volume":"27","author":"Luo","year":"2025","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.cellsig.2026.112696_bb0205","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-9434-2_1","article-title":"High-resolution mass spectrometry to identify and quantify acetylation protein targets","volume":"1983","author":"Schilling","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.cellsig.2026.112696_bb0210","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/978-1-62703-637-5_13","article-title":"Chemical acetylation and deacetylation","volume":"1077","author":"Fritz","year":"2013","journal-title":"Methods Mol. Biol."},{"issue":"5","key":"10.1016\/j.cellsig.2026.112696_bb0215","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.cell.2020.10.036","article-title":"Proteogenomic landscape of breast cancer tumorigenesis and targeted therapy","volume":"183","author":"Krug","year":"2020","journal-title":"Cell"},{"issue":"18","key":"10.1016\/j.cellsig.2026.112696_bb0220","doi-asserted-by":"crossref","first-page":"3945","DOI":"10.1016\/j.cell.2023.07.013","article-title":"Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation","volume":"186","author":"Geffen","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.cellsig.2026.112696_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2025.103834","article-title":"Oxidative stress-induced ZEB1 acetylation drives a hybrid epithelial-mesenchymal phenotype and promotes lung metastasis in triple-negative breast cancer","volume":"86","author":"Guo","year":"2025","journal-title":"Redox Biol."},{"issue":"20","key":"10.1016\/j.cellsig.2026.112696_bb0230","article-title":"KAT6A acetylation of SMAD3 regulates myeloid-derived suppressor cell recruitment, metastasis, and immunotherapy in triple-negative breast cancer","volume":"8","author":"Yu","year":"2021","journal-title":"Adv. Sci. (Weinh)"},{"issue":"9","key":"10.1016\/j.cellsig.2026.112696_bb0235","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25094647","article-title":"Type II interleukin-4 receptor activation in basal breast cancer cells promotes tumor progression via metabolic and epigenetic modulation","volume":"25","author":"Williams","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.cellsig.2026.112696_bb0240","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/s41435-023-00202-1","article-title":"ACAT1-mediated METTL3 acetylation inhibits cell migration and invasion in triple negative breast cancer","volume":"24","author":"Zhang","year":"2023","journal-title":"Genes Immun."},{"issue":"6","key":"10.1016\/j.cellsig.2026.112696_bb0245","doi-asserted-by":"crossref","first-page":"387","DOI":"10.14348\/molcells.2023.2192","article-title":"Microtubule acetylation-specific inhibitors induce cell death and mitotic arrest via JNK\/AP-1 activation in triple-negative breast cancer cells","volume":"46","author":"Ahn","year":"2023","journal-title":"Mol. Cell"},{"issue":"11","key":"10.1016\/j.cellsig.2026.112696_bb0250","doi-asserted-by":"crossref","first-page":"11255","DOI":"10.21037\/apm-21-1139","article-title":"Phase II study of chidamide in combination with cisplatin in patients with metastatic triple-negative breast cancer","volume":"10","author":"Meng","year":"2021","journal-title":"Ann. Palliat. Med."},{"issue":"41","key":"10.1016\/j.cellsig.2026.112696_bb0255","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ado6492","article-title":"Mechanism of degrader-targeted protein ubiquitinability","volume":"10","author":"Crowe","year":"2024","journal-title":"Sci. Adv."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0260","doi-asserted-by":"crossref","first-page":"6635","DOI":"10.1038\/s41467-023-42420-1","article-title":"RING finger protein 13 protects against nonalcoholic steatohepatitis by targeting STING-relayed signaling pathways","volume":"14","author":"Lin","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cellsig.2026.112696_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104634","article-title":"Pancreatic ductal adenocarcinoma ubiquitination profiling reveals specific prognostic and theranostic markers","volume":"92","author":"El Kaoutari","year":"2023","journal-title":"EBioMedicine"},{"issue":"7","key":"10.1016\/j.cellsig.2026.112696_bb0270","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1021\/acs.biochem.9b00602","article-title":"A general in vitro assay for studying enzymatic activities of the ubiquitin system","volume":"59","author":"Zuo","year":"2020","journal-title":"Biochemistry"},{"issue":"19","key":"10.1016\/j.cellsig.2026.112696_bb0275","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adr3173","article-title":"Targeting PSMD14 combined with arachidonic acid induces synthetic lethality via FADS1 m(6)a modification in triple-negative breast cancer","volume":"11","author":"Yu","year":"2025","journal-title":"Sci. Adv."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0280","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/s41523-025-00779-y","article-title":"TRIM39-mediated deubiquitination upregulates RNF168 to evade autophagy-ferroptosis in triple-negative breast cancer","volume":"11","author":"Yao","year":"2025","journal-title":"NPJ Breast Cancer"},{"key":"10.1016\/j.cellsig.2026.112696_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2025.102536","article-title":"TCEB2 promotes m2 polarization of macrophages in triple negative breast cancer by mediating ubiquitination degradation of slit2 through recruiting NEDD4","volume":"62","author":"Liu","year":"2025","journal-title":"Transl. Oncol."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0290","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s00018-025-05833-3","article-title":"Synergistic inhibition of TNBC by USP33 and TAP63 through autophagy and ferroptosis activation","volume":"82","author":"Qu","year":"2025","journal-title":"Cell. Mol. Life Sci."},{"issue":"16","key":"10.1016\/j.cellsig.2026.112696_bb0295","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.1158\/0008-5472.CAN-24-3476","article-title":"CARM1-mediated MAP2K4 methylation potentiates the oncogenic functions of MAP2K4 and constitutes a targetable dependency in triple-negative breast cancer","volume":"85","author":"Kim","year":"2025","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0300","doi-asserted-by":"crossref","first-page":"8716","DOI":"10.1038\/s41467-025-63745-z","article-title":"A histone-centric multi-omics study shows that increased H3K4 methylation sustains triple-negative breast cancer phenotypes","volume":"16","author":"Noberini","year":"2025","journal-title":"Nat. Commun."},{"issue":"7","key":"10.1016\/j.cellsig.2026.112696_bb0305","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1038\/s41556-024-01446-3","article-title":"Loss of kmt2c or kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3","volume":"26","author":"Seehawer","year":"2024","journal-title":"Nat. Cell Biol."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0310","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1038\/s42003-025-08433-w","article-title":"OXCT1 promotes triple negative breast cancer immune escape via modulating succinylation modification of PGK1","volume":"8","author":"Zhang","year":"2025","journal-title":"Commun. Biol."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0315","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1186\/s13046-023-02789-9","article-title":"SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation","volume":"42","author":"Liu","year":"2023","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0320","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s12017-014-8336-4","article-title":"Sumoylation of p35 modulates p35\/cyclin-dependent kinase (cdk) 5 complex activity","volume":"17","author":"B\u00fcchner","year":"2015","journal-title":"NeuroMolecular Med."},{"issue":"4","key":"10.1016\/j.cellsig.2026.112696_bb0325","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1089\/adt.2008.0188","article-title":"A toolbox approach to high-throughput TR-FRET-based SUMOylation and DeSUMOylation assays","volume":"7","author":"Carlson","year":"2009","journal-title":"Assay Drug Dev. Technol."},{"key":"10.1016\/j.cellsig.2026.112696_bb0330","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/bs.pmbts.2021.01.022","article-title":"CRISPR\/Cas9 in epigenetics studies of health and disease","volume":"181","author":"Sar","year":"2021","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"issue":"17","key":"10.1016\/j.cellsig.2026.112696_bb0335","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1016\/j.devcel.2025.04.005","article-title":"Sumoylated etv1 establishes mouse mammary cancer stem cells that support tumorigenesis by non-stem cancer cells","volume":"60","author":"Li","year":"2025","journal-title":"Dev. Cell"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0340","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s13058-025-02054-1","article-title":"SENP5 drives breast cancer progression through deSUMOYlation of CDK1","volume":"27","author":"Chen","year":"2025","journal-title":"Breast Cancer Res."},{"issue":"7","key":"10.1016\/j.cellsig.2026.112696_bb0345","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1038\/s41418-025-01472-0","article-title":"ZNF451 collaborates with RNF8 to regulate RNF168 localization and amplify ubiquitination signaling to promote DNA damage repair and regulate radiosensitivity","volume":"32","author":"Xu","year":"2025","journal-title":"Cell Death Differ."},{"issue":"2","key":"10.1016\/j.cellsig.2026.112696_bb0350","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s13402-024-01005-w","article-title":"SUMOylation regulates the aggressiveness of breast cancer-associated fibroblasts","volume":"48","author":"Mart\u00ednez-L\u00f3pez","year":"2025","journal-title":"Cell. Oncol. (Dordr)"},{"issue":"11","key":"10.1016\/j.cellsig.2026.112696_bb0355","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1158\/2767-9764.CRC-25-0243","article-title":"A first-in-human study of the SUMOylation inhibitor subasumstat in patients with advanced\/metastatic solid tumors or relapsed\/refractory hematologic malignancies","volume":"5","author":"Juric","year":"2025","journal-title":"Cancer Res. Commun."},{"key":"10.1016\/j.cellsig.2026.112696_bb0360","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.949252","article-title":"The role and mechanism of histone lactylation in health and diseases","volume":"13","author":"Xie","year":"2022","journal-title":"Front. Genet."},{"issue":"11","key":"10.1016\/j.cellsig.2026.112696_bb0365","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.70070","article-title":"Lactylation in cancer: mechanisms in tumour biology and therapeutic potentials","volume":"14","author":"He","year":"2024","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.cellsig.2026.112696_bb0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2025.117934","article-title":"Unveiling lactylation modification: a new hope for cancer treatment","volume":"184","author":"Luo","year":"2025","journal-title":"Biomed. Pharmacother."},{"issue":"9","key":"10.1016\/j.cellsig.2026.112696_bb0375","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1038\/s41388-026-03681-4","article-title":"BRD4 orchestrates the metabolic-epigenetic regulation of GM-CSF expression and secretion to drive PD-L1+ macrophage-mediated immune evasion in triple-negative breast cancer","volume":"45","author":"Diao","year":"2026","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0380","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1186\/s12967-025-06246-3","article-title":"Cancer-associated fibroblasts promote doxorubicin resistance in triple-negative breast cancer through enhancing ZFP64 histone lactylation to regulate ferroptosis","volume":"23","author":"Zhang","year":"2025","journal-title":"J. Transl. Med."},{"issue":"5","key":"10.1016\/j.cellsig.2026.112696_bb0385","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1021\/acs.jproteome.0c01053","article-title":"Uromodulin isolation and its N-glycosylation analysis by NanoLC-MS\/MS","volume":"20","author":"Li","year":"2021","journal-title":"J. Proteome Res."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0390","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.bbrc.2011.09.027","article-title":"Development of recombinant aleuria aurantia lectins with altered binding specificities to fucosylated glycans","volume":"414","author":"Romano","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.cellsig.2026.112696_bb0395","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1053\/j.gastro.2024.03.037","article-title":"Impaired glycosylation of gastric mucins drives gastric tumorigenesis and serves as a novel therapeutic target","volume":"167","author":"Arai","year":"2024","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.cellsig.2026.112696_bb0400","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ccell.2018.01.009","article-title":"Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1","volume":"33","author":"Li","year":"2018","journal-title":"Cancer Cell"},{"key":"10.1016\/j.cellsig.2026.112696_bb0405","doi-asserted-by":"crossref","first-page":"1088560","DOI":"10.3389\/fimmu.2022.1088560","article-title":"B7 family protein glycosylation: promising novel targets in tumor treatment","volume":"13","author":"Xiao","year":"2022","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0410","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1038\/s41467-021-22618-x","article-title":"FUT8-mediated aberrant n-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer","volume":"12","author":"Huang","year":"2021","journal-title":"Nat. Commun."},{"issue":"8","key":"10.1016\/j.cellsig.2026.112696_bb0415","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.7150\/thno.81760","article-title":"Roles of glycosylation at the cancer cell surface: opportunities for large scale glycoproteomics","volume":"13","author":"\u010caval","year":"2023","journal-title":"Theranostics"},{"issue":"10","key":"10.1016\/j.cellsig.2026.112696_bb0420","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1021\/acs.accounts.2c00115","article-title":"Chiral posttranslational modification to lysine \u03b5-amino groups","volume":"55","author":"Moreno-Yruela","year":"2022","journal-title":"Acc. Chem. Res."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0425","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1186\/s12944-024-02364-x","article-title":"Ketogenesis promotes triple-negative breast cancer metastasis via calpastatin \u03b2-hydroxybutyrylation","volume":"23","author":"Jiang","year":"2024","journal-title":"Lipids Health Dis."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0430","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s40170-024-00339-1","article-title":"Metabolic alterations and cellular responses to beta-Hydroxybutyrate treatment in breast cancer cells","volume":"12","author":"Fulman-Levy","year":"2024","journal-title":"Cancer Metab."},{"issue":"9","key":"10.1016\/j.cellsig.2026.112696_bb0435","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abe2771","article-title":"The regulatory enzymes and protein substrates for the lysine \u03b2-hydroxybutyrylation pathway","volume":"7","author":"Huang","year":"2021","journal-title":"Sci. Adv."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0440","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s42003-021-02805-8","article-title":"DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer","volume":"4","author":"Shen","year":"2021","journal-title":"Commun. Biol."},{"key":"10.1016\/j.cellsig.2026.112696_bb0445","doi-asserted-by":"crossref","first-page":"1571446","DOI":"10.3389\/fimmu.2025.1571446","article-title":"Succinylation-related molecular activities in cancer: metabolic adaptations, immune landscape, and prognostic significance in colorectal cancer","volume":"16","author":"Jiang","year":"2025","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0450","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/s41467-021-27778-4","article-title":"Streamlined single-cell proteomics by an integrated microfluidic chip and data-independent acquisition mass spectrometry","volume":"13","author":"Gebreyesus","year":"2022","journal-title":"Nat. Commun."},{"issue":"16","key":"10.1016\/j.cellsig.2026.112696_bb0455","doi-asserted-by":"crossref","DOI":"10.1172\/JCI177357","article-title":"LOXL2-induced PEAR1 ser891 phosphorylation suppresses CD44 degradation and promotes triple-negative breast cancer metastasis","volume":"134","author":"Shen","year":"2024","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0460","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/s41420-025-02368-1","article-title":"Capsanthin inhibits migration and reduces n-linked glycosylation of PD-L1 via the EZH2-PD-L1 axis in triple-negative breast cancer brain metastasis","volume":"11","author":"Chien","year":"2025","journal-title":"Cell Death Discov."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0465","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/s41523-021-00300-1","article-title":"Signaling of MK2 sustains robust AP1 activity for triple negative breast cancer tumorigenesis through direct phosphorylation of JAB1","volume":"7","author":"Chen","year":"2021","journal-title":"NPJ Breast Cancer"},{"key":"10.1016\/j.cellsig.2026.112696_bb0470","series-title":"ABL Kinases Modulate EZH2 Phosphorylation and Signaling in Metastatic Triple Negative Breast Cancer","author":"Colemon","year":"2025"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0475","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s10549-025-07623-8","article-title":"Formosanin c inhibits triple-negative breast cancer progression by suppressing the phosphorylation of STAT3 and the polarization of m2 macrophages","volume":"211","author":"Dai","year":"2025","journal-title":"Breast Cancer Res. Treat."},{"issue":"9","key":"10.1016\/j.cellsig.2026.112696_bb0480","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1002\/jcp.24545","article-title":"SKP2 overexpression is associated with increased serine 10 phosphorylation of p27 (pSer10p27) in triple-negative breast cancer","volume":"229","author":"Fagan-Solis","year":"2014","journal-title":"J. Cell. Physiol."},{"issue":"6","key":"10.1016\/j.cellsig.2026.112696_bb0485","doi-asserted-by":"crossref","DOI":"10.3892\/ijo.2023.5521","article-title":"P2Y(2)R-mediated transactivation of VEGFR2 through src phosphorylation is associated with ESM-1 overexpression in radiotherapy-resistant-triple negative breast cancer cells","volume":"62","author":"Jin","year":"2023","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.cellsig.2026.112696_bb0490","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154087","article-title":"A chalcone-syringaldehyde hybrid inhibits triple-negative breast cancer cell proliferation and migration by inhibiting CKAP2-mediated FAK and STAT3 phosphorylation","volume":"101","author":"Jin","year":"2022","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0495","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/s41420-024-01956-x","article-title":"CK2\u03b1-mediated phosphorylation of GRP94 facilitates the metastatic cascade in triple-negative breast cancer","volume":"10","author":"Kim","year":"2024","journal-title":"Cell Death Discov."},{"issue":"4","key":"10.1016\/j.cellsig.2026.112696_bb0500","doi-asserted-by":"crossref","first-page":"652","DOI":"10.4062\/biomolther.2025.012","article-title":"OZ-001 suppresses the growth of triple-negative breast cancer and pancreatic cancer by targeting STAT3 phosphorylation and the calcium signaling pathway","volume":"33","author":"Kim","year":"2025","journal-title":"Biomol. Ther. (Seoul)"},{"issue":"5","key":"10.1016\/j.cellsig.2026.112696_bb0505","doi-asserted-by":"crossref","DOI":"10.3390\/biom9050170","article-title":"Novel galiellalactone analogues can target STAT3 phosphorylation and cause apoptosis in triple-negative breast cancer","volume":"9","author":"Ko","year":"2019","journal-title":"Biomolecules"},{"issue":"7","key":"10.1016\/j.cellsig.2026.112696_bb0510","doi-asserted-by":"crossref","DOI":"10.3390\/cells12070980","article-title":"S1P1 threonine 236 phosphorylation mediates the invasiveness of triple-negative breast cancer and sensitivity to FTY720","volume":"12","author":"Laroche","year":"2023","journal-title":"Cells"},{"issue":"24","key":"10.1016\/j.cellsig.2026.112696_bb0515","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232415872","article-title":"PKR-mediated phosphorylation of eIF2a and CHK1 is associated with doxorubicin-mediated apoptosis in HCC1143 triple-negative breast cancer cells","volume":"23","author":"Lee","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cellsig.2026.112696_bb0520","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.3389\/fonc.2020.01108","article-title":"Long non-coding RNA MNX1-AS1 promotes progression of triple negative breast cancer by enhancing phosphorylation of stat3","volume":"10","author":"Li","year":"2020","journal-title":"Front. Oncol."},{"key":"10.1016\/j.cellsig.2026.112696_bb0525","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.216842","article-title":"SOD1-high fibroblasts derived exosomal miR-3960 promotes cisplatin resistance in triple-negative breast cancer by suppressing BRSK2-mediated phosphorylation of PIMREG","volume":"590","author":"Li","year":"2024","journal-title":"Cancer Lett."},{"issue":"9","key":"10.1016\/j.cellsig.2026.112696_bb0530","doi-asserted-by":"crossref","DOI":"10.1002\/fsn3.70737","article-title":"Isodeoxyelephantopin promotes cell death in triple-negative breast cancer by blocking STAT3 phosphorylation and enhancing the effectiveness of paclitaxel","volume":"13","author":"Lin","year":"2025","journal-title":"Food Sci. Nutr."},{"issue":"4","key":"10.1016\/j.cellsig.2026.112696_bb0535","doi-asserted-by":"crossref","first-page":"173","DOI":"10.21037\/atm-22-73","article-title":"Polydatin down-regulates the phosphorylation level of STAT3 and induces pyroptosis in triple-negative breast cancer mice with a high-fat diet","volume":"10","author":"Liu","year":"2022","journal-title":"Ann. Transl. Med."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0540","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13045-020-01021-x","article-title":"HOMER3 facilitates growth factor-mediated \u03b2-catenin tyrosine phosphorylation and activation to promote metastasis in triple negative breast cancer","volume":"14","author":"Liu","year":"2021","journal-title":"J. Hematol. Oncol."},{"issue":"17","key":"10.1016\/j.cellsig.2026.112696_bb0545","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231710119","article-title":"Hypoxia triggers TAZ phosphorylation in basal a triple negative breast cancer cells","volume":"23","author":"Liu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.cellsig.2026.112696_bb0550","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1038\/s41388-018-0466-y","article-title":"JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity","volume":"38","author":"Liu","year":"2019","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0555","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/s13046-021-01941-7","article-title":"Inhibition of retinoic acid receptor \u03b1 phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3","volume":"40","author":"Lou","year":"2021","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.cellsig.2026.112696_bb0560","first-page":"11","article-title":"Dual target of EGFR and mTOR suppresses triple-negative breast cancer cell growth by regulating the phosphorylation of mTOR downstream proteins","volume":"15","author":"Ma","year":"2023","journal-title":"Breast Cancer"},{"issue":"2","key":"10.1016\/j.cellsig.2026.112696_bb0565","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s10549-014-3102-8","article-title":"Abrogating phosphorylation of eIF4B is required for EGFR and mTOR inhibitor synergy in triple-negative breast cancer","volume":"147","author":"Madden","year":"2014","journal-title":"Breast Cancer Res. Treat."},{"issue":"3","key":"10.1016\/j.cellsig.2026.112696_bb0570","doi-asserted-by":"crossref","first-page":"322","DOI":"10.4062\/biomolther.2017.235","article-title":"Gomisin g inhibits the growth of triple-negative breast cancer cells by suppressing AKT phosphorylation and decreasing cyclin d1","volume":"26","author":"Maharjan","year":"2018","journal-title":"Biomol. Ther. (Seoul)"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0575","doi-asserted-by":"crossref","first-page":"5114","DOI":"10.1038\/s41467-019-13105-5","article-title":"CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer","volume":"10","author":"Nie","year":"2019","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0580","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0171169","article-title":"Dasatinib inhibits c-src phosphorylation and prevents the proliferation of triple-negative breast cancer (TNBC) cells which overexpress Syndecan-binding protein (SDCBP)","volume":"12","author":"Qian","year":"2017","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0585","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1158\/0008-5472.CAN-19-1310","article-title":"Phosphorylation of RAB7 by TBK1\/IKK\u03b5 regulates innate immune signaling in triple-negative breast cancer","volume":"80","author":"Ritter","year":"2020","journal-title":"Cancer Res."},{"issue":"23","key":"10.1016\/j.cellsig.2026.112696_bb0590","doi-asserted-by":"crossref","first-page":"37172","DOI":"10.18632\/oncotarget.16420","article-title":"Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer","volume":"8","author":"Roseweir","year":"2017","journal-title":"Oncotarget"},{"issue":"6","key":"10.1016\/j.cellsig.2026.112696_bb0595","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1038\/s41388-021-02142-4","article-title":"NRG1 regulates fra-1 transcription and metastasis of triple-negative breast cancer cells via the c-Myc ubiquitination as manipulated by ERK1\/2-mediated fbxw7 phosphorylation","volume":"41","author":"Shu","year":"2022","journal-title":"Oncogene"},{"issue":"3","key":"10.1016\/j.cellsig.2026.112696_bb0600","doi-asserted-by":"crossref","DOI":"10.1016\/j.neo.2014.03.008","article-title":"KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancer","volume":"16","author":"Singel","year":"2014","journal-title":"Neoplasia"},{"issue":"23","key":"10.1016\/j.cellsig.2026.112696_bb0605","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25235728","article-title":"Pharmacological inhibition of CDK8 in triple-negative breast cancer cell line MDA-MB-468 increases E2F1 protein, induces phosphorylation of STAT3 and apoptosis","volume":"25","author":"Spear","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.cellsig.2026.112696_bb0610","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2020.108722","article-title":"Exploring the structural significance of molecular switch mechanism alias motif phosphorylation in wnt\/\u03b2-catenin and their crucial role in triple-negative breast cancer","volume":"698","author":"Sriroopreddy","year":"2021","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.cellsig.2026.112696_bb0615","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.jare.2023.09.011","article-title":"CDK2-activated TRIM32 phosphorylation and nuclear translocation promotes radioresistance in triple-negative breast cancer","volume":"61","author":"Tang","year":"2024","journal-title":"J. Adv. Res."},{"issue":"20","key":"10.1016\/j.cellsig.2026.112696_bb0620","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.4161\/15384101.2014.950126","article-title":"Inhibition of CDK-mediated phosphorylation of smad3 results in decreased oncogenesis in triple negative breast cancer cells","volume":"13","author":"Tarasewicz","year":"2014","journal-title":"Cell Cycle"},{"key":"10.1016\/j.cellsig.2026.112696_bb0625","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154769","article-title":"\u0392, \u03b2-Dimethylacrylshikonin potentiates paclitaxel activity, suppresses immune evasion and triple negative breast cancer progression via STAT3Y705 phosphorylation inhibition based on network pharmacology and transcriptomics analysis","volume":"114","author":"Wu","year":"2023","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0630","doi-asserted-by":"crossref","first-page":"17663","DOI":"10.1038\/s41598-019-54184-0","article-title":"Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer","volume":"9","author":"Yeh","year":"2019","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.cellsig.2026.112696_bb0635","first-page":"2142","article-title":"Deciphering the performance of polo-like kinase 1 in triple-negative breast cancer progression according to the centromere protein u-phosphorylation pathway","volume":"11","author":"Zhao","year":"2021","journal-title":"Am. J. Cancer Res."},{"issue":"10","key":"10.1016\/j.cellsig.2026.112696_bb0640","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2025.113552","article-title":"Phosphorylation of plectin by Akt3 promotes triple-negative breast cancer cell invasive migration","volume":"28","author":"Zheng","year":"2025","journal-title":"iScience"},{"issue":"5","key":"10.1016\/j.cellsig.2026.112696_bb0645","first-page":"5735","article-title":"EZH2 and histone deacetylase inhibitors induce apoptosis in triple negative breast cancer cells by differentially increasing h3 lys(27) acetylation in the BIM gene promoter and enhancers","volume":"14","author":"Huang","year":"2017","journal-title":"Oncol. Lett."},{"issue":"27","key":"10.1016\/j.cellsig.2026.112696_bb0650","doi-asserted-by":"crossref","first-page":"23383","DOI":"10.18632\/oncotarget.4345","article-title":"Extracellularly secreted APE1\/Ref-1 triggers apoptosis in triple-negative breast cancer cells via RAGE binding, which is mediated through acetylation","volume":"6","author":"Lee","year":"2015","journal-title":"Oncotarget"},{"issue":"3","key":"10.1016\/j.cellsig.2026.112696_bb0655","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/path.5676","article-title":"BOP1 confers chemoresistance of triple-negative breast cancer by promoting CBP-mediated \u03b2-catenin acetylation","volume":"254","author":"Li","year":"2021","journal-title":"J. Pathol."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0660","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s10549-020-06033-2","article-title":"HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells","volume":"186","author":"Oba","year":"2021","journal-title":"Breast Cancer Res. Treat."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0665","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s13072-019-0290-9","article-title":"Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer","volume":"12","author":"Senapati","year":"2019","journal-title":"Epigenetics Chromatin"},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0670","doi-asserted-by":"crossref","first-page":"16257","DOI":"10.1038\/s41598-019-52723-3","article-title":"Acetylation of conserved DVL-1 lysines regulates its nuclear translocation and binding to gene promoters in triple-negative breast cancer","volume":"9","author":"Sharma","year":"2019","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0675","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/s41420-022-01269-x","article-title":"Acetylation of checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer","volume":"8","author":"Xu","year":"2022","journal-title":"Cell Death Discov."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0680","doi-asserted-by":"crossref","first-page":"2478670","DOI":"10.1080\/15384047.2025.2478670","article-title":"PCK2 promotes invasion and epithelial-to-mesenchymal transition in triple-negative breast cancer by promoting TGF-\u03b2\/SMAD3 signaling through inhibiting TRIM67-mediated SMAD3 ubiquitination","volume":"26","author":"Chang","year":"2025","journal-title":"Cancer Biol. Ther."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0685","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/s41420-025-02518-5","article-title":"CCNE1 stabilizes ANLN by counteracting FZR1-mediated the ubiquitination modification to promotes triple negative breast cancer cell stemness and progression","volume":"11","author":"Dai","year":"2025","journal-title":"Cell Death Discov."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0690","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s13045-020-01016-8","article-title":"Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triplenegativebreastcancer cells","volume":"14","author":"Ding","year":"2021","journal-title":"J. Hematol. Oncol."},{"issue":"6","key":"10.1016\/j.cellsig.2026.112696_bb0695","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-005461","article-title":"Circ-0000512 inhibits PD-L1 ubiquitination through sponging miR-622\/CMTM6 axis to promote triple-negative breast cancer and immune escape","volume":"11","author":"Dong","year":"2023","journal-title":"J. Immunother. Cancer"},{"issue":"7","key":"10.1016\/j.cellsig.2026.112696_bb0700","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/s41419-021-03963-7","article-title":"Exosomal annexin a6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer","volume":"12","author":"Li","year":"2021","journal-title":"Cell Death Dis."},{"issue":"7","key":"10.1016\/j.cellsig.2026.112696_bb0705","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2025.167958","article-title":"TRIM34 inhibits triple-negative breast cancer progression by attenuating fatty acid synthesis via facilitating FASN ubiquitination","volume":"1871","author":"Li","year":"2025","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"issue":"5","key":"10.1016\/j.cellsig.2026.112696_bb0710","article-title":"RNF126-mediated MRE11 ubiquitination activates the DNA damage response and confers resistance of triple-negative breast cancer to radiotherapy","volume":"10","author":"Liu","year":"2023","journal-title":"Adv. Sci. (Weinh)"},{"issue":"16","key":"10.1016\/j.cellsig.2026.112696_bb0715","first-page":"4483","article-title":"Hydnocarpin inhibits malignant progression of triple negative breast cancer via CNOT4-mediated ubiquitination and degradation of YAP","volume":"48","author":"Ou","year":"2023","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"key":"10.1016\/j.cellsig.2026.112696_bb0720","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.jare.2024.11.004","article-title":"Tetrahydrocurcumin targets TRIP13 inhibiting the interaction of TRIP13\/USP7\/c-FLIP to mediate c-FLIP ubiquitination in triple-negative breast cancer","volume":"75","author":"Sun","year":"2025","journal-title":"J. Adv. Res."},{"issue":"1","key":"10.1016\/j.cellsig.2026.112696_bb0725","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13020-021-00426-1","article-title":"Shikonin promotes ubiquitination and degradation of cIAP1\/2-mediated apoptosis and necrosis in triple negative breast cancer cells","volume":"16","author":"Wang","year":"2021","journal-title":"Chin. Med."},{"key":"10.1016\/j.cellsig.2026.112696_bb0730","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.174970","article-title":"Eupaformosanin induces apoptosis and ferroptosis through ubiquitination of mutant p53 in triple-negative breast cancer","volume":"924","author":"Wei","year":"2022","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.cellsig.2026.112696_bb0735","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.18112","article-title":"METTL14\/miR-29c-3p axis drives aerobic glycolysis to promote triple-negative breast cancer progression though TRIM9-mediated PKM2 ubiquitination","volume":"28","author":"Wu","year":"2024","journal-title":"J. Cell. Mol. Med."},{"issue":"11","key":"10.1016\/j.cellsig.2026.112696_bb0740","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.70097","article-title":"Chaperonin-containing TCP1 subunit 6A inhibition via TRIM21-mediated k48-linked ubiquitination suppresses triple-negative breast cancer progression through the AKT signalling pathway","volume":"14","author":"Yang","year":"2024","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.cellsig.2026.112696_bb0745","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2022.215797","article-title":"LINC01194 recruits NUMA1 to promote ubiquitination of RYR2 to enhance malignant progression in triple-negative breast cancer","volume":"544","author":"Zhai","year":"2022","journal-title":"Cancer Lett."},{"key":"10.1016\/j.cellsig.2026.112696_bb0750","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.freeradbiomed.2025.04.052","article-title":"Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation","volume":"235","author":"Zhang","year":"2025","journal-title":"Free Radic. Biol. Med."},{"issue":"12","key":"10.1016\/j.cellsig.2026.112696_bb0755","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/s41419-023-06383-x","article-title":"TRIM21-mediated sohlh2 ubiquitination suppresses m2 macrophage polarization and progression of triple-negative breast cancer","volume":"14","author":"Zhang","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.cellsig.2026.112696_bb0760","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2025.111530","article-title":"Antimicrobial peptide WK-13-3D promotes apoptosis, autophagy, and ubiquitination in triple-negative breast cancer via binding immunoglobulin protein (BiP)","volume":"415","author":"Zhang","year":"2025","journal-title":"Chem. Biol. Interact."}],"container-title":["Cellular Signalling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656826003517?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0898656826003517?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T06:27:56Z","timestamp":1785911276000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0898656826003517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":152,"alternative-id":["S0898656826003517"],"URL":"https:\/\/doi.org\/10.1016\/j.cellsig.2026.112696","relation":{},"ISSN":["0898-6568"],"issn-type":[{"value":"0898-6568","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Post-translational modifications in triple-negative breast cancer: research status and translation challenges","name":"articletitle","label":"Article Title"},{"value":"Cellular Signalling","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cellsig.2026.112696","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112696"}}