{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:50:45Z","timestamp":1790711445148,"version":"4.1.0"},"reference-count":16,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,1,26]],"date-time":"2016-01-26T00:00:00Z","timestamp":1453766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.celrep.2016.01.062","type":"journal-article","created":{"date-parts":[[2016,2,18]],"date-time":"2016-02-18T11:01:39Z","timestamp":1455793299000},"page":"1867-1875","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":76,"title":["A Long Non-coding RNA, lncLGR, Regulates Hepatic Glucokinase Expression and Glycogen Storage during Fasting"],"prefix":"10.1016","volume":"14","author":[{"given":"Xiangbo","family":"Ruan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Cangelosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiming","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2016.01.062_bib1","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.cmet.2015.04.003","article-title":"De novo reconstruction of adipose tissue transcriptomes reveals long non-coding RNA regulators of brown adipocyte development","volume":"21","author":"Alvarez-Dominguez","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.celrep.2016.01.062_bib2","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1261\/rna.2254110","article-title":"Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles","volume":"16","author":"Chaudhury","year":"2010","journal-title":"RNA"},{"key":"10.1016\/j.celrep.2016.01.062_bib3","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.molcel.2014.04.025","article-title":"LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1\/S checkpoint","volume":"54","author":"Dimitrova","year":"2014","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2016.01.062_bib4","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nature11233","article-title":"Landscape of transcription in human cells","volume":"489","author":"Djebali","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2016.01.062_bib5","doi-asserted-by":"crossref","first-page":"12737","DOI":"10.1073\/pnas.96.22.12737","article-title":"Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes","volume":"96","author":"Foretz","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2016.01.062_bib6","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1101\/gr.135350.111","article-title":"GENCODE: the reference human genome annotation for The ENCODE Project","volume":"22","author":"Harrow","year":"2012","journal-title":"Genome Res."},{"key":"10.1016\/j.celrep.2016.01.062_bib7","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.cell.2010.06.040","article-title":"A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response","volume":"142","author":"Huarte","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2016.01.062_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3389\/fgene.2014.00057","article-title":"Regulation of metabolism by long, non-coding RNAs","volume":"5","author":"Kornfeld","year":"2014","journal-title":"Front. Genet."},{"key":"10.1016\/j.celrep.2016.01.062_bib9","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1073\/pnas.1313768111","article-title":"The long noncoding RNA THRIL regulates TNF\u03b1 expression through its interaction with hnRNPL","volume":"111","author":"Li","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2016.01.062_bib10","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.cmet.2015.02.004","article-title":"A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice","volume":"21","author":"Li","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.celrep.2016.01.062_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/iub.411","article-title":"Liver glucokinase: An overview on the regulatory mechanisms of its activity","volume":"63","author":"Massa","year":"2011","journal-title":"IUBMB Life"},{"key":"10.1016\/j.celrep.2016.01.062_bib12","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.cmet.2012.08.010","article-title":"Human \u03b2 cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes","volume":"16","author":"Mor\u00e1n","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.celrep.2016.01.062_bib13","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.cell.2007.05.022","article-title":"Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs","volume":"129","author":"Rinn","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2016.01.062_bib14","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1074\/jbc.M308391200","article-title":"The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase\/protein kinase B pathway","volume":"279","author":"Roth","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2016.01.062_bib15","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.molcel.2011.08.018","article-title":"Molecular mechanisms of long noncoding RNAs","volume":"43","author":"Wang","year":"2011","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2016.01.062_bib16","doi-asserted-by":"crossref","first-page":"22636","DOI":"10.1074\/jbc.M113.463901","article-title":"Crystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation","volume":"288","author":"Zhang","year":"2013","journal-title":"J.\u00a0Biol. Chem."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124716300407?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124716300407?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T09:50:07Z","timestamp":1761904207000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124716300407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S2211124716300407"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2016.01.062","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Long Non-coding RNA, lncLGR, Regulates Hepatic Glucokinase Expression and Glycogen Storage during Fasting","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2016.01.062","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}