{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T03:40:32Z","timestamp":1781149232648,"version":"3.54.1"},"reference-count":84,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T00:00:00Z","timestamp":1614211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010247","name":"Schizophrenia Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012317","name":"UCLH Biomedical Research Centre","doi-asserted-by":"publisher","award":["D79\/543369\/D-OTH\/170890"],"award-info":[{"award-number":["D79\/543369\/D-OTH\/170890"]}],"id":[{"id":"10.13039\/501100012317","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009362","name":"South London and Maudsley NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["085475\/Z\/08\/Z"],"award-info":[{"award-number":["085475\/Z\/08\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["085475\/B\/08\/Z"],"award-info":[{"award-number":["085475\/B\/08\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["MC_PC_16014"],"award-info":[{"award-number":["MC_PC_16014"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","award":["NIHR200756"],"award-info":[{"award-number":["NIHR200756"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","award":["PDA\/02\/06\/016"],"award-info":[{"award-number":["PDA\/02\/06\/016"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007229","name":"Harvard University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007229","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000051","name":"National Human Genome Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000051","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009981","name":"Mental Health Research UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009981","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["D79\/543369\/D-OTH\/170890"],"award-info":[{"award-number":["D79\/543369\/D-OTH\/170890"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["G0901310"],"award-info":[{"award-number":["G0901310"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["G1100583"],"award-info":[{"award-number":["G1100583"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH116948"],"award-info":[{"award-number":["R01MH116948"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH109687"],"award-info":[{"award-number":["R01MH109687"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH112180"],"award-info":[{"award-number":["R01MH112180"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","award":["747429"],"award-info":[{"award-number":["747429"]}],"id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016210","name":"Psychiatry Research Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016210","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.celrep.2021.108868","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T17:18:09Z","timestamp":1616087889000},"page":"108868","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Transcriptome-wide association study reveals two genes that influence mismatch negativity"],"prefix":"10.1016","volume":"34","author":[{"given":"Anjali","family":"Bhat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haritz","family":"Irizar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan Hilge","family":"Thygesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karoline","family":"Kuchenbaecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Pain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick A.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eirini","family":"Zartaloudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine","family":"Harju-Sepp\u00e4nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Austin-Zimmerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baihan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Muir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Summerfelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming Michael","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Bruce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricio","family":"O\u2019Donnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak P.","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Friston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Elliot","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Hua","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvira","family":"Bramon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2021.108868_bib1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3389\/fpsyt.2013.00047","article-title":"The computational anatomy of psychosis","volume":"4","author":"Adams","year":"2013","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib2","doi-asserted-by":"crossref","first-page":"4555","DOI":"10.1172\/JCI64896","article-title":"IL-13-induced airway mucus production is attenuated by MAPK13 inhibition","volume":"122","author":"Alevy","year":"2012","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.celrep.2021.108868_bib3","series-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2013"},{"key":"10.1016\/j.celrep.2021.108868_bib4","doi-asserted-by":"crossref","first-page":"eaap8757","DOI":"10.1126\/science.aap8757","article-title":"Analysis of shared heritability in common disorders of the brain","volume":"360","author":"Anttila","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.celrep.2021.108868_bib5","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ijpsycho.2014.03.008","article-title":"Mismatch negativity indexes illness-specific impairments of cortical plasticity in schizophrenia: a comparison with bipolar disorder and Alzheimer\u2019s disease","volume":"95","author":"Baldeweg","year":"2015","journal-title":"Int. J. Psychophysiol."},{"key":"10.1016\/j.celrep.2021.108868_bib6","doi-asserted-by":"crossref","first-page":"e0212379","DOI":"10.1371\/journal.pone.0212379","article-title":"Hallucinations both in and out of context: an active inference account","volume":"14","author":"Benrimoh","year":"2019","journal-title":"PLoS ONE"},{"key":"10.1016\/j.celrep.2021.108868_bib7","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1038\/s41588-019-0378-y","article-title":"Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids","volume":"51","author":"Bentley","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib8","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/mp.2012.73","article-title":"Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder","volume":"17","author":"Bergen","year":"2012","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib9","doi-asserted-by":"crossref","first-page":"D810","DOI":"10.1093\/nar\/gkt1225","article-title":"The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse","volume":"42","author":"Blake","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2021.108868_bib10","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.biopsych.2010.09.057","article-title":"Prediction of psychosis by mismatch negativity","volume":"69","author":"Bodatsch","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0920-9964(03)00132-4","article-title":"Mismatch negativity in schizophrenia: a family study","volume":"67","author":"Bramon","year":"2004","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.celrep.2021.108868_bib12","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.neuroimage.2005.05.022","article-title":"Is the P300 wave an endophenotype for schizophrenia? A meta-analysis and a family study","volume":"27","author":"Bramon","year":"2005","journal-title":"Neuroimage"},{"key":"10.1016\/j.celrep.2021.108868_bib13","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.biopsych.2013.03.033","article-title":"A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation","volume":"75","author":"Bramon","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib14","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/brain\/awy345","article-title":"The interplay between genetics, cognition and schizophrenia","volume":"142","author":"Calafato","year":"2019","journal-title":"Brain"},{"key":"10.1016\/j.celrep.2021.108868_bib15","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.pnpbp.2017.11.016","article-title":"PSD95: a synaptic protein implicated in schizophrenia or autism?","volume":"82","author":"Coley","year":"2018","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib16","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S1388-2457(99)00296-5","article-title":"EOG correction of blinks with saccade coefficients: a test and revision of the aligned-artefact average solution","volume":"111","author":"Croft","year":"2000","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.celrep.2021.108868_bib17","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/nrn1785","article-title":"Pathways modulating neural KCNQ\/M (Kv7) potassium channels","volume":"6","author":"Delmas","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.celrep.2021.108868_bib18","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.schres.2011.12.024","article-title":"Abnormal intrinsic and extrinsic connectivity within the magnetic mismatch negativity brain network in schizophrenia: a preliminary study","volume":"135","author":"Dima","year":"2012","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.celrep.2021.108868_bib19","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/S1053-8119(03)00389-6","article-title":"Prefrontal cortex involvement in preattentive auditory deviance detection: neuroimaging and electrophysiological evidence","volume":"20","author":"Doeller","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.celrep.2021.108868_bib20","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1093\/bioinformatics\/btu014","article-title":"Efficient haplotype matching and storage using the positional Burrows-Wheeler transform (PBWT)","volume":"30","author":"Durbin","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2021.108868_bib21","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1001\/archpsyc.1978.01770310043002","article-title":"A diagnostic interview: the schedule for affective disorders and schizophrenia","volume":"35","author":"Endicott","year":"1978","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib22","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.biopsych.2015.08.025","article-title":"A Meta-Analysis of Mismatch Negativity in Schizophrenia: From Clinical Risk to Disease Specificity and Progression","volume":"79","author":"Erickson","year":"2016","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib23","series-title":"Structured Clinical Interview for DSM-IV Axis I Disorders: SCID-I Adminstration Booklet","author":"First","year":"1997"},{"key":"10.1016\/j.celrep.2021.108868_bib24","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1098\/rstb.2005.1622","article-title":"A theory of cortical responses","volume":"360","author":"Friston","year":"2005","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.celrep.2021.108868_bib25","doi-asserted-by":"crossref","first-page":"e1006696","DOI":"10.1371\/journal.pgen.1006696","article-title":"Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene","volume":"13","author":"Fujihira","year":"2017","journal-title":"PLoS Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib26","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1038\/ng.3367","article-title":"A gene-based association method for mapping traits using reference transcriptome data","volume":"47","author":"Gamazon","year":"2015","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib27","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1038\/s41588-019-0409-8","article-title":"Multi-tissue transcriptome analyses identify genetic mechanisms underlying neuropsychiatric traits","volume":"51","author":"Gamazon","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib28","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.clinph.2008.11.029","article-title":"The mismatch negativity: a review of underlying mechanisms","volume":"120","author":"Garrido","year":"2009","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.celrep.2021.108868_bib29","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.biopsych.2011.08.022","article-title":"High dimensional endophenotype ranking in the search for major depression risk genes","volume":"71","author":"Glahn","year":"2012","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib30","doi-asserted-by":"crossref","first-page":"11780","DOI":"10.1038\/s41598-019-48162-9","article-title":"A qPCR expression assay of IFI44L gene differentiates viral from bacterial infections in febrile children","volume":"9","author":"G\u00f3mez-Carballa","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2021.108868_bib31","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1176\/appi.ajp.160.4.636","article-title":"The endophenotype concept in psychiatry: etymology and strategic intentions","volume":"160","author":"Gottesman","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib32","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/s41398-020-00940-0","article-title":"Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort","volume":"10","author":"Grama","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib33","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1007\/s12031-014-0402-8","article-title":"Comparative proteomic approach in rat model of absence epilepsy","volume":"55","author":"G\u00fcrol","year":"2015","journal-title":"J.\u00a0Mol. Neurosci."},{"key":"10.1016\/j.celrep.2021.108868_bib34","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1038\/s41588-018-0092-1","article-title":"Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights","volume":"50","author":"Gusev","year":"2018","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib35","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/1550059416645980","article-title":"Mismatch Negativity in First-Episode Schizophrenia: A Meta-Analysis","volume":"48","author":"Haigh","year":"2017","journal-title":"Clin. EEG Neurosci."},{"key":"10.1016\/j.celrep.2021.108868_bib36","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/hmg\/ddz253","article-title":"A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia","volume":"29","author":"Hall","year":"2020","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib37","series-title":"Helmholtz\u2019s Treatise on Physiological Optics","author":"Helmholtz","year":"1962"},{"key":"10.1016\/j.celrep.2021.108868_bib38","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.biopsych.2017.08.017","article-title":"Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register","volume":"83","author":"Hilker","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib39","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1016\/j.clinph.2012.03.011","article-title":"Mismatch negativity and low frequency oscillations in schizophrenia families","volume":"123","author":"Hong","year":"2012","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.celrep.2021.108868_bib40","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/s41588-019-0364-4","article-title":"Gene expression imputation across multiple brain regions provides insights into schizophrenia risk","volume":"51","author":"Huckins","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib41","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.ijpsycho.2016.07.516","article-title":"Endophenotype best practices","volume":"111","author":"Iacono","year":"2017","journal-title":"Int. J. Psychophysiol."},{"key":"10.1016\/j.celrep.2021.108868_bib42","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s10519-018-9914-2","article-title":"Characterizing the Relation Between Expression QTLs and Complex Traits: Exploring the Role of Tissue Specificity","volume":"48","author":"Ip","year":"2018","journal-title":"Behav. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib44","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S1388-2457(98)00011-X","article-title":"Stability of the mismatch negativity under different stimulus and attention conditions","volume":"110","author":"Kathmann","year":"1999","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.celrep.2021.108868_bib45","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.celrep.2021.108868_bib46","first-page":"3","article-title":"The ten-twenty electrode system of the International Federation","volume":"52","author":"Klem","year":"1999","journal-title":"Electroencephalogr. Clin. Neurophysiol. Suppl."},{"key":"10.1016\/j.celrep.2021.108868_bib47","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.tins.2004.10.007","article-title":"The Bayesian brain: the role of uncertainty in neural coding and computation","volume":"27","author":"Knill","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.celrep.2021.108868_bib48","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1177\/1745691619895071","article-title":"Making Sense of the World: Infant Learning From a Predictive Processing Perspective","volume":"15","author":"K\u00f6ster","year":"2020","journal-title":"Perspect. Psychol. Sci."},{"key":"10.1016\/j.celrep.2021.108868_bib49","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.1093\/bioinformatics\/bts474","article-title":"Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood","volume":"28","author":"Lee","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2021.108868_bib50","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1038\/s41598-019-39132-2","article-title":"Genetic variants differentially associated with rheumatoid arthritis and systemic lupus erythematosus reveal the disease-specific biology","volume":"9","author":"Lim","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2021.108868_bib51","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.schres.2017.12.018","article-title":"Knowing when to stop: aberrant precision and evidence accumulation in schizophrenia","volume":"197","author":"Limongi","year":"2018","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.celrep.2021.108868_bib52","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1038\/ng.3679","article-title":"Reference-based phasing using the Haplotype Reference Consortium panel","volume":"48","author":"Loh","year":"2016","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib85","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1038\/ng.3643","article-title":"A reference panel of 64,976 haplotypes for genotype imputation","volume":"48","author":"McCarthy","year":"2016","journal-title":"Nat Genet"},{"key":"10.1016\/j.celrep.2021.108868_bib53","doi-asserted-by":"crossref","first-page":"8227","DOI":"10.1523\/JNEUROSCI.4255-12.2013","article-title":"Free energy, precision and learning: the role of cholinergic neuromodulation","volume":"33","author":"Moran","year":"2013","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.celrep.2021.108868_bib54","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1093\/bioinformatics\/btq280","article-title":"Evoker: a visualization tool for genotype intensity data","volume":"26","author":"Morris","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2021.108868_bib55","series-title":"Attention and Brain Function","author":"N\u00e4\u00e4t\u00e4nen","year":"1992"},{"key":"10.1016\/j.celrep.2021.108868_bib56","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0001-6918(78)90006-9","article-title":"Early selective-attention effect on evoked potential reinterpreted","volume":"42","author":"N\u00e4\u00e4t\u00e4nen","year":"1978","journal-title":"Acta Psychol. (Amst.)"},{"key":"10.1016\/j.celrep.2021.108868_bib57","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.clinph.2011.09.020","article-title":"The mismatch negativity (MMN)--a unique window to disturbed central auditory processing in ageing and different clinical conditions","volume":"123","author":"N\u00e4\u00e4t\u00e4nen","year":"2012","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.celrep.2021.108868_bib58","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1006\/nimg.2001.0970","article-title":"Differential contribution of frontal and temporal cortices to auditory change detection: fMRI and ERP results","volume":"15","author":"Opitz","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.celrep.2021.108868_bib59","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.biopsych.2019.04.034","article-title":"Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics","volume":"86","author":"Pain","year":"2019","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib60","doi-asserted-by":"crossref","first-page":"339","DOI":"10.3389\/fbioe.2019.00339","article-title":"Screening of Methylation Signature and Gene Functions Associated With the Subtypes of Isocitrate Dehydrogenase-Mutation Gliomas","volume":"7","author":"Pan","year":"2019","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.celrep.2021.108868_bib61","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/s41588-018-0059-2","article-title":"Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection","volume":"50","author":"Pardi\u00f1as","year":"2018","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.copsyc.2018.10.006","article-title":"Attention or salience?","volume":"29","author":"Parr","year":"2019","journal-title":"Curr. Opin. Psychol."},{"key":"10.1016\/j.celrep.2021.108868_bib63","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.neuron.2015.04.022","article-title":"Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia","volume":"86","author":"Pocklington","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2021.108868_bib64","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1126\/science.aan3458","article-title":"Pavlovian conditioning-induced hallucinations result from overweighting of perceptual priors","volume":"357","author":"Powers","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.celrep.2021.108868_bib65","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"Purcell","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib66","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/hbm.23035","article-title":"Impaired prefrontal synaptic gain in people with psychosis and their relatives during the mismatch negativity","volume":"37","author":"Ranlund","year":"2016","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.celrep.2021.108868_bib67","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2021.108868_bib68","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/cne.21810","article-title":"Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain","volume":"510","author":"Saenz del Burgo","year":"2008","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.celrep.2021.108868_bib69","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1469-8986.1986.tb00696.x","article-title":"A solution for reliable and valid reduction of ocular artifacts, applied to the P300 ERP","volume":"23","author":"Semlitsch","year":"1986","journal-title":"Psychophysiology"},{"key":"10.1016\/j.celrep.2021.108868_bib70","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.schres.2011.09.022","article-title":"Reduced mismatch negativity predates the onset of psychosis","volume":"134","author":"Shaikh","year":"2012","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.celrep.2021.108868_bib71","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/0006-3223(91)90126-7","article-title":"Mismatch negativity: an index of a preattentive processing deficit in schizophrenia","volume":"30","author":"Shelley","year":"1991","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib72","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s002329900515","article-title":"Differential asparagine-linked glycosylation of voltage-gated K+ channels in mammalian brain and in transfected cells","volume":"168","author":"Shi","year":"1999","journal-title":"J.\u00a0Membr. Biol."},{"key":"10.1016\/j.celrep.2021.108868_bib73","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1038\/ng.3865","article-title":"Reevaluation of SNP heritability in complex human traits","volume":"49","author":"Speed","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib74","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/s41588-019-0397-8","article-title":"Genome-wide association study identifies 30 loci associated with bipolar disorder","volume":"51","author":"Stahl","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib75","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1111\/2041-210X.12129","article-title":"Estimating heritability using genomic data","volume":"4","author":"Stanton-Geddes","year":"2013","journal-title":"Methods Ecol. Evol."},{"key":"10.1016\/j.celrep.2021.108868_bib76","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.biopsych.2018.05.015","article-title":"The Predictive Coding Account of Psychosis","volume":"84","author":"Sterzer","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib77","doi-asserted-by":"crossref","first-page":"9691","DOI":"10.1073\/pnas.152333599","article-title":"Endo-beta-N-acetylglucosaminidase, an enzyme involved in processing of free oligosaccharides in the cytosol","volume":"99","author":"Suzuki","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2021.108868_bib78","article-title":"Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study","author":"Thygesen","year":"2020","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.celrep.2021.108868_bib79","doi-asserted-by":"crossref","first-page":"3642","DOI":"10.4049\/jimmunol.1003292","article-title":"Highly activated cytotoxic CD8 T\u00a0cells express protective IL-10 at the peak of coronavirus-induced encephalitis","volume":"186","author":"Trandem","year":"2011","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.108868_bib80","doi-asserted-by":"crossref","first-page":"e1006423","DOI":"10.1371\/journal.pgen.1006423","article-title":"Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues","volume":"12","author":"Wheeler","year":"2016","journal-title":"PLoS Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib81","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1093\/bioinformatics\/bti529","article-title":"PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data","volume":"21","author":"Wigginton","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2021.108868_bib82","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/ng.608","article-title":"Common SNPs explain a large proportion of the heritability for human height","volume":"42","author":"Yang","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib83","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ajhg.2010.11.011","article-title":"GCTA: a tool for genome-wide complex trait analysis","volume":"88","author":"Yang","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.celrep.2021.108868_bib84","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s12859-018-2057-x","article-title":"lme4qtl: linear mixed models with flexible covariance structure for genetic studies of related individuals","volume":"19","author":"Ziyatdinov","year":"2018","journal-title":"BMC Bioinformatics"}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124721001820?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124721001820?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T10:41:44Z","timestamp":1778841704000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124721001820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":84,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S2211124721001820"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2021.108868","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptome-wide association study reveals two genes that influence mismatch negativity","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2021.108868","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"108868"}}