{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:01:41Z","timestamp":1790816501487,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,5]],"date-time":"2021-08-05T00:00:00Z","timestamp":1628121600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007393","name":"Association Fran\u00e7aise contre les Myopathies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007393","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008164","name":"Muscular Dystrophy UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008164","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"ERC","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011724","name":"Muscular Dystrophy UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011724","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.celrep.2021.109601","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T10:48:27Z","timestamp":1629802107000},"page":"109601","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["The non-muscle ADF\/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies"],"prefix":"10.1016","volume":"36","author":[{"given":"Nicolas","family":"Vignier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Chatzifrangkeskou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Pinton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Wioland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaut","family":"Marais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9gane","family":"Lemaitre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Le Dour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Peccate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9borah","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Schmitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria-Grazia","family":"Biferi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na\u00efra","family":"Naouar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coline","family":"Macquart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maud","family":"Beuvin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Decostre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gis\u00e8le","family":"Bonne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Romet-Lemonne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard J.","family":"Worman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco Saverio","family":"Tedesco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"J\u00e9gou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Muchir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2021.109601_bib1","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/323560a0","article-title":"The nuclear lamina is a meshwork of intermediate-type filaments","volume":"323","author":"Aebi","year":"1986","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109601_bib2","doi-asserted-by":"crossref","first-page":"C205","DOI":"10.1152\/ajpcell.00408.2008","article-title":"Slow myosin heavy chain expression in the absence of muscle activity","volume":"296","author":"Agbulut","year":"2009","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.celrep.2021.109601_bib3","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1086\/510402","article-title":"Nemaline myopathy with minicores caused by mutation of the CFL2 gene encoding the skeletal muscle actin-binding protein, cofilin-2","volume":"80","author":"Agrawal","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib4","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1093\/hmg\/dds053","article-title":"Normal myofibrillar development followed by progressive sarcomeric disruption with actin accumulations in a mouse Cfl2 knockout demonstrates requirement of cofilin-2 for muscle maintenance","volume":"21","author":"Agrawal","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib5","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.devcel.2019.10.023","article-title":"ERK1\/2 phosphorylation of FHOD connects signaling and nuclear positioning alternations in cardiac laminopathy","volume":"51","author":"Antoku","year":"2019","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2021.109601_bib6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/hmg\/ddi017","article-title":"Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies","volume":"14","author":"Arimura","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib7","doi-asserted-by":"crossref","first-page":"R273","DOI":"10.1016\/j.cub.2008.02.002","article-title":"ADF\/cofilin","volume":"18","author":"Bamburg","year":"2008","journal-title":"Curr. Biol."},{"key":"10.1016\/j.celrep.2021.109601_bib8","doi-asserted-by":"crossref","first-page":"C411","DOI":"10.1152\/ajpcell.00192.2005","article-title":"Impact of sarcoglycan complex on mechanical signal transduction in murine skeletal muscle","volume":"290","author":"Barton","year":"2006","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.celrep.2021.109601_bib9","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1016\/j.ymthe.2017.05.017","article-title":"A New AAV10-U7-mediated gene therapy prolongs survival and restores function in an ALS mouse model","volume":"25","author":"Biferi","year":"2017","journal-title":"Mol. Ther."},{"key":"10.1016\/j.celrep.2021.109601_bib10","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/6799","article-title":"Mutations in the gene encoding lamin A\/C cause autosomal dominant Emery-Dreifuss muscular dystrophy","volume":"21","author":"Bonne","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib11","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.3389\/fphys.2018.01533","article-title":"The pathogenesis and therapies of striated muscle laminopathies","volume":"9","author":"Brull","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.celrep.2021.109601_bib12","doi-asserted-by":"crossref","first-page":"4401","DOI":"10.1128\/MCB.23.12.4401-4415.2003","article-title":"Accumulation of Fra-1 in ras-transformed cells depends on both transcriptional autoregulation and MEK-dependent posttranslational stabilization","volume":"23","author":"Casalino","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.celrep.2021.109601_bib13","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1093\/hmg\/ddy215","article-title":"Cofilin-1 phosphorylation catalyzed by ERK1\/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A\/C gene mutation","volume":"27","author":"Chatzifrangkeskou","year":"2018","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1126\/science.1155313","article-title":"Leiomodin is an actin filament nucleator in muscle cells","volume":"320","author":"Chereau","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.celrep.2021.109601_bib15","doi-asserted-by":"crossref","first-page":"144ra102","DOI":"10.1126\/scitranslmed.3003875","article-title":"Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A\/C gene mutation","volume":"4","author":"Choi","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.celrep.2021.109601_bib16","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1101\/gad.1652708","article-title":"Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin","volume":"22","author":"Dechat","year":"2008","journal-title":"Genes Dev."},{"key":"10.1016\/j.celrep.2021.109601_bib17","doi-asserted-by":"crossref","first-page":"19565","DOI":"10.1074\/jbc.M117.808378","article-title":"Phosphomimetic S3D cofilin binds but only weakly severs actin filaments","volume":"292","author":"Elam","year":"2017","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2021.109601_bib18","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/j.1399-0004.1987.tb03302.x","article-title":"X-linked muscular dystrophy with early contractures and cardiomyopathy (Emery-Dreifuss type)","volume":"32","author":"Emery","year":"1987","journal-title":"Clin. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib19","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1056\/NEJM199912023412302","article-title":"Missense mutations in the rod domain of the lamin A\/C gene as causes of dilated cardiomyopathy and conduction-system disease","volume":"341","author":"Fatkin","year":"1999","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.celrep.2021.109601_bib20","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.devcel.2019.08.006","article-title":"Mechanical forces regulate cardiomyocyte myofilament maturation via the VCL-SSH1-CFL axis","volume":"51","author":"Fukuda","year":"2019","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2021.109601_bib21","doi-asserted-by":"crossref","first-page":"3529","DOI":"10.1172\/JCI74994","article-title":"KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy","volume":"124","author":"Garg","year":"2014","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.celrep.2021.109601_bib22","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/nature02263","article-title":"Protein degradation and protection against misfolded or damaged proteins","volume":"426","author":"Goldberg","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109601_bib23","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1242\/jcs.01717","article-title":"gamma-Sarcoglycan deficiency increases cell contractility, apoptosis and MAPK pathway activation but does not affect adhesion","volume":"118","author":"Griffin","year":"2005","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109601_bib24","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/nature12105","article-title":"Lamin A\/C and emerin regulate MKL1-SRF activity by modulating actin dynamics","volume":"497","author":"Ho","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109601_bib25","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2021.109601_bib26","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/173973a0","article-title":"Changes in the cross-striations of muscle during contraction and stretch and their structural interpretation","volume":"173","author":"Huxley","year":"1954","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109601_bib27","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1113\/jphysiol.1958.sp006110","article-title":"Measurement of the striations of isolated muscle fibres with the interference microscope","volume":"144","author":"Huxley","year":"1958","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.celrep.2021.109601_bib28","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/biostatistics\/4.2.249","article-title":"Exploration, normalization, and summaries of high density oligonucleotide array probe level data","volume":"4","author":"Irizarry","year":"2003","journal-title":"Biostatistics"},{"key":"10.1016\/j.celrep.2021.109601_bib29","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.devcel.2014.09.002","article-title":"Cofilin-2 controls actin filament length in muscle sarcomeres","volume":"31","author":"Kremneva","year":"2014","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2021.109601_bib30","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1096\/fj.03-0453com","article-title":"Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers","volume":"18","author":"Kumar","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.celrep.2021.109601_bib31","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1093\/hmg\/ddr126","article-title":"Muscle-specific expression of insulin-like growth factor 1 improves outcome in Lama2Dy-w mice, a model for congenital muscular dystrophy type 1A","volume":"20","author":"Kumar","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib32","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1177\/153537020422900608","article-title":"Altered activity of signaling pathways in diaphragm and tibialis anterior muscle of dystrophic mice","volume":"229","author":"Lang","year":"2004","journal-title":"Exp. Biol. Med. (Maywood)"},{"key":"10.1016\/j.celrep.2021.109601_bib33","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1186\/1471-2105-6-269","article-title":"ErmineJ: tool for functional analysis of gene expression data sets","volume":"6","author":"Lee","year":"2005","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.celrep.2021.109601_bib34","doi-asserted-by":"crossref","first-page":"16321","DOI":"10.1016\/S0021-9258(19)85424-8","article-title":"Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C","volume":"268","author":"Lin","year":"1993","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2021.109601_bib35","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-5-reviews3007","article-title":"The ADF\/cofilin family: actin-remodeling proteins","volume":"3","author":"Maciver","year":"2002","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2021.109601_bib36","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1080\/19491034.2018.1462635","article-title":"Clinical aspects of Emery-Dreifuss muscular dystrophy","volume":"9","author":"Madej-Pilarczyk","year":"2018","journal-title":"Nucleus"},{"key":"10.1016\/j.celrep.2021.109601_bib37","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/nprot.2015.057","article-title":"Efficient derivation and inducible differentiation of expandable skeletal myogenic cells from human ES and patient-specific iPS cells","volume":"10","author":"Maffioletti","year":"2015","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2021.109601_bib38","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1152\/japplphysiol.00126.2006","article-title":"Contractile properties of EDL and soleus muscles of myostatin-deficient mice","volume":"101","author":"Mendias","year":"2006","journal-title":"J Appl Physiol (1985)"},{"key":"10.1016\/j.celrep.2021.109601_bib39","doi-asserted-by":"crossref","first-page":"R444","DOI":"10.1152\/ajpregu.00377.2013","article-title":"Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle","volume":"307","author":"Mouisel","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.celrep.2021.109601_bib40","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1093\/hmg\/9.9.1453","article-title":"Identification of mutations in the gene encoding lamins A\/C in autosomal dominant limb girdle muscular dystrophy with atrioventricular conduction disturbances (LGMD1B)","volume":"9","author":"Muchir","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib41","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1172\/JCI29042","article-title":"Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy","volume":"117","author":"Muchir","year":"2007","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.celrep.2021.109601_bib42","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/2044-5040-3-17","article-title":"Inhibition of extracellular signal-regulated kinase 1\/2 signaling has beneficial effects on skeletal muscle in a mouse model of Emery-Dreifuss muscular dystrophy caused by lamin A\/C gene mutation","volume":"3","author":"Muchir","year":"2013","journal-title":"Skelet. Muscle"},{"key":"10.1016\/j.celrep.2021.109601_bib43","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1126\/science.275.5298.400","article-title":"Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases","volume":"275","author":"Musti","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.celrep.2021.109601_bib44","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1002\/cm.20476","article-title":"Dynamic regulation of sarcomeric actin filaments in striated muscle","volume":"67","author":"Ono","year":"2010","journal-title":"Cytoskeleton (Hoboken)"},{"key":"10.1016\/j.celrep.2021.109601_bib45","doi-asserted-by":"crossref","first-page":"15280","DOI":"10.1016\/S0021-9258(17)36603-6","article-title":"Characterization of a novel cofilin isoform that is predominantly expressed in mammalian skeletal muscle","volume":"269","author":"Ono","year":"1994","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2021.109601_bib46","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1083\/jcb.145.3.491","article-title":"UNC-60B, an ADF\/cofilin family protein, is required for proper assembly of actin into myofibrils in Caenorhabditis elegans body wall muscle","volume":"145","author":"Ono","year":"1999","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.celrep.2021.109601_bib47","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1242\/jcs.114.24.4435","article-title":"Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy","volume":"114","author":"Ostlund","year":"2001","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109601_bib48","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2021.109601_bib49","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/ana.21417","article-title":"De novo LMNA mutations cause a new form of congenital muscular dystrophy","volume":"64","author":"Quijano-Roy","year":"2008","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.celrep.2021.109601_bib50","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/bioinformatics\/btf877","article-title":"Identifying differentially expressed genes using false discovery rate controlling procedures","volume":"19","author":"Reiner","year":"2003","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2021.109601_bib51","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2021.109601_bib52","doi-asserted-by":"crossref","first-page":"5325","DOI":"10.1242\/jcs.114041","article-title":"Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies","volume":"126","author":"Sandri","year":"2013","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109601_bib53","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2021.109601_bib54","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1242\/jcs.046805","article-title":"Contractility-dependent actin dynamics in cardiomyocyte sarcomeres","volume":"122","author":"Skwarek-Maruszewska","year":"2009","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109601_bib55","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/mus.23312","article-title":"Altered mitogen-activated protein kinase signaling in dystrophic (mdx) muscle","volume":"46","author":"Smythe","year":"2012","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.celrep.2021.109601_bib56","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.3389\/fphys.2018.01332","article-title":"Modeling Skeletal Muscle Laminopathies Using Human Induced Pluripotent Stem Cells Carrying Pathogenic LMNA Mutations","volume":"9","author":"Steele-Stallard","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.celrep.2021.109601_bib57","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1091\/mbc.01-07-0331","article-title":"The three mouse actin-depolymerizing factor\/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics","volume":"13","author":"Vartiainen","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.celrep.2021.109601_bib58","first-page":"100664","article-title":"Effect of genetic background on the cardiac phenotype in a mouse model of Emery-Dreifuss muscular dystrophy","volume":"19","author":"Vignier","year":"2019","journal-title":"Biochem. Biophys. Rep."},{"key":"10.1016\/j.celrep.2021.109601_bib59","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1016\/j.cub.2017.05.048","article-title":"ADF\/Cofilin accelerates actin dynamics by severing filaments and promoting their depolymerization at both ends","volume":"27","author":"Wioland","year":"2017","journal-title":"Curr. Biol."},{"key":"10.1016\/j.celrep.2021.109601_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/hmg\/ddt387","article-title":"Depletion of extracellular signal-regulated kinase 1 in mice with cardiomyopathy caused by lamin A\/C gene mutation partially prevents pathology before isoenzyme activation","volume":"23","author":"Wu","year":"2014","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2021.109601_bib61","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/onc.2009.319","article-title":"Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin-proteasome pathway","volume":"29","author":"Yoo","year":"2010","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2021.109601_bib62","doi-asserted-by":"crossref","first-page":"4693","DOI":"10.1172\/JCI75199","article-title":"Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy","volume":"124","author":"Yuen","year":"2014","journal-title":"J.\u00a0Clin. Invest."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124721010391?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124721010391?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T11:30:29Z","timestamp":1761910229000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124721010391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":62,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S2211124721010391"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2021.109601","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The non-muscle ADF\/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2021.109601","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"109601"}}