{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T09:08:54Z","timestamp":1779354534878,"version":"3.51.4"},"reference-count":64,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,6]],"date-time":"2021-08-06T00:00:00Z","timestamp":1628208000000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","award":["2011622044\/201808130149"],"award-info":[{"award-number":["2011622044\/201808130149"]}],"id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["IG 11675"],"award-info":[{"award-number":["IG 11675"]}],"id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007232","name":"Radiumhemmets Forskningsfonder","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007232","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008732","name":"Uehara Memorial Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006313","name":"Barncancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006313","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007158","name":"Fondazione Ricerca Molinette","doi-asserted-by":"publisher","award":["8893\/5"],"award-info":[{"award-number":["8893\/5"]}],"id":[{"id":"10.13039\/501100007158","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.celrep.2021.109616","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T10:51:05Z","timestamp":1629802265000},"page":"109616","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Amot\/integrin protein complex transmits mechanical forces required for vascular expansion"],"prefix":"10.1016","volume":"36","author":[{"given":"Yuanyuan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumako","family":"Kameishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppina","family":"Barutello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujuan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas P.","family":"Tobin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Nicosia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Hennig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Kung-Chun","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martial","family":"Balland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas H.","family":"Barker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Cavallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Holmgren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2021.109616_bib1","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1101\/gad.432007","article-title":"Angiomotin regulates endothelial cell migration during embryonic angiogenesis","volume":"21","author":"Aase","year":"2007","journal-title":"Genes Dev."},{"key":"10.1016\/j.celrep.2021.109616_bib2","doi-asserted-by":"crossref","first-page":"5139","DOI":"10.1073\/pnas.072650799","article-title":"Fibronectin extension and unfolding within cell matrix fibrils controlled by cytoskeletal tension","volume":"99","author":"Baneyx","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2021.109616_bib3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/cm.21313","article-title":"Non-muscle myosin-IIA is critical for podocyte f-actin organization, contractility, and attenuation of cell motility","volume":"73","author":"Bondzie","year":"2016","journal-title":"Cytoskeleton (Hoboken)"},{"key":"10.1016\/j.celrep.2021.109616_bib4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-1119(02)00928-9","article-title":"Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains","volume":"298","author":"Bratt","year":"2002","journal-title":"Gene"},{"key":"10.1016\/j.celrep.2021.109616_bib5","doi-asserted-by":"crossref","first-page":"C595","DOI":"10.1152\/ajpcell.00270.2001","article-title":"Traction fields, moments, and strain energy that cells exert on their surroundings","volume":"282","author":"Butler","year":"2002","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.celrep.2021.109616_bib6","doi-asserted-by":"crossref","first-page":"7110","DOI":"10.1021\/acsnano.7b02755","article-title":"Detection of an Integrin-Binding Mechanoswitch within Fibronectin during Tissue Formation and Fibrosis","volume":"11","author":"Cao","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.celrep.2021.109616_bib7","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1471-2105-14-128","article-title":"Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool","volume":"14","author":"Chen","year":"2013","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.celrep.2021.109616_bib8","doi-asserted-by":"crossref","first-page":"18871","DOI":"10.1074\/jbc.M410762200","article-title":"Fibronectin regulates latent transforming growth factor-beta (TGF beta) by controlling matrix assembly of latent TGF beta-binding protein-1","volume":"280","author":"Dallas","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2021.109616_bib9","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/ncb3115","article-title":"A molecular mechanotransduction pathway regulates collective migration of epithelial cells","volume":"17","author":"Das","year":"2015","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature10137","article-title":"Role of YAP\/TAZ in mechanotransduction","volume":"474","author":"Dupont","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109616_bib11","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ceb.2010.08.010","article-title":"Dynamics of endothelial cell behavior in sprouting angiogenesis","volume":"22","author":"Eilken","year":"2010","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib12","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1111\/j.1742-4658.2006.05216.x","article-title":"p130-angiomotin associates to actin and controls endothelial cell shape","volume":"273","author":"Ernkvist","year":"2006","journal-title":"FEBS J."},{"key":"10.1016\/j.celrep.2021.109616_bib13","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1182\/blood-2008-04-153874","article-title":"The Amot\/Patj\/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells","volume":"113","author":"Ernkvist","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.celrep.2021.109616_bib14","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/nm0195-27","article-title":"Angiogenesis in cancer, vascular, rheumatoid and other disease","volume":"1","author":"Folkman","year":"1995","journal-title":"Nat. Med."},{"key":"10.1016\/j.celrep.2021.109616_bib15","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s10456-007-9065-1","article-title":"Development of the retinal vasculature","volume":"10","author":"Fruttiger","year":"2007","journal-title":"Angiogenesis"},{"key":"10.1016\/j.celrep.2021.109616_bib16","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/S0896-6273(00)80244-5","article-title":"PDGF mediates a neuron-astrocyte interaction in the developing retina","volume":"17","author":"Fruttiger","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2021.109616_bib17","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/35099066","article-title":"Transmembrane crosstalk between the extracellular matrix-cytoskeleton crosstalk","volume":"2","author":"Geiger","year":"2001","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib18","first-page":"3","article-title":"How do endothelial cells orientate?","author":"Gerhardt","year":"2005","journal-title":"EXS"},{"key":"10.1016\/j.celrep.2021.109616_bib19","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1083\/jcb.200302047","article-title":"VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia","volume":"161","author":"Gerhardt","year":"2003","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib20","doi-asserted-by":"crossref","first-page":"9540","DOI":"10.1038\/s41598-017-10102-w","article-title":"The E-cadherin\/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching","volume":"7","author":"Hildebrand","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2021.109616_bib21","doi-asserted-by":"crossref","first-page":"4159","DOI":"10.1242\/jcs.192054","article-title":"The integrin adhesome network at a glance","volume":"129","author":"Horton","year":"2016","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109616_bib22","doi-asserted-by":"crossref","first-page":"757","DOI":"10.15252\/msb.20145625","article-title":"Ultrasensitive proteome analysis using paramagnetic bead technology","volume":"10","author":"Hughes","year":"2014","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib23","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1038\/ncomms4743","article-title":"AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion","volume":"5","author":"Hultin","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2021.109616_bib24","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0092-8674(02)00971-6","article-title":"Integrins: bidirectional, allosteric signaling machines","volume":"110","author":"Hynes","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2021.109616_bib25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1083\/jcb.109.1.317","article-title":"Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in\u00a0vitro: role of extracellular matrix","volume":"109","author":"Ingber","year":"1989","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib26","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/0021-9290(95)00095-X","article-title":"Cell shape, cytoskeletal mechanics, and cell cycle control in angiogenesis","volume":"28","author":"Ingber","year":"1995","journal-title":"J.\u00a0Biomech."},{"key":"10.1016\/j.celrep.2021.109616_bib27","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1242\/jcs.107.9.2499","article-title":"Astrocytes modulate retinal vasculogenesis: effects on fibronectin expression","volume":"107","author":"Jiang","year":"1994","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109616_bib28","doi-asserted-by":"crossref","first-page":"18267","DOI":"10.1073\/pnas.0907518106","article-title":"Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites","volume":"106","author":"Klotzsch","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2021.109616_bib29","doi-asserted-by":"crossref","first-page":"W90","DOI":"10.1093\/nar\/gkw377","article-title":"Enrichr: a comprehensive gene set enrichment analysis web server 2016 update","volume":"44","author":"Kuleshov","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2021.109616_bib30","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.ceb.2008.06.001","article-title":"The role of integrin binding sites in fibronectin matrix assembly in\u00a0vivo","volume":"20","author":"Leiss","year":"2008","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib31","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.bpj.2008.10.009","article-title":"Cell traction forces direct fibronectin matrix assembly","volume":"96","author":"Lemmon","year":"2009","journal-title":"Biophys. J."},{"key":"10.1016\/j.celrep.2021.109616_bib32","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1038\/ncomms3251","article-title":"Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms","volume":"4","author":"Leung","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2021.109616_bib33","doi-asserted-by":"crossref","first-page":"3803","DOI":"10.1242\/jcs.00694","article-title":"Loss of responsiveness to chemotactic factors by deletion of the C-terminal protein interaction site of angiomotin","volume":"116","author":"Levchenko","year":"2003","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109616_bib34","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1016\/S0002-9440(10)63568-7","article-title":"Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases","volume":"163","author":"Lin","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.celrep.2021.109616_bib35","doi-asserted-by":"crossref","first-page":"12393","DOI":"10.18632\/oncotarget.7161","article-title":"Angiomotin promotes renal epithelial and carcinoma cell proliferation by retaining the nuclear YAP","volume":"7","author":"Lv","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.celrep.2021.109616_bib36","doi-asserted-by":"crossref","first-page":"5749","DOI":"10.1038\/ncomms6749","article-title":"Cell dipole behaviour revealed by ECM sub-cellular geometry","volume":"5","author":"Mandal","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2021.109616_bib37","doi-asserted-by":"crossref","first-page":"4708","DOI":"10.1073\/pnas.1011123108","article-title":"Cell-ECM traction force modulates endogenous tension at cell-cell contacts","volume":"108","author":"Maruthamuthu","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2021.109616_bib38","doi-asserted-by":"crossref","first-page":"e0120872","DOI":"10.1371\/journal.pone.0120872","article-title":"Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors","volume":"10","author":"Murphy","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.celrep.2021.109616_bib39","doi-asserted-by":"crossref","first-page":"3861","DOI":"10.1242\/jcs.00059","article-title":"Fibronectin at a glance","volume":"115","author":"Pankov","year":"2002","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109616_bib40","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1038\/nprot.2010.113","article-title":"Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice","volume":"5","author":"Pitulescu","year":"2010","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2021.109616_bib41","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.cell.2011.08.039","article-title":"Basic and therapeutic aspects of angiogenesis","volume":"146","author":"Potente","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2021.109616_bib42","doi-asserted-by":"crossref","first-page":"jcs226514","DOI":"10.1242\/jcs.226514","article-title":"Talin-mediated force transmission and talin rod domain unfolding independently regulate adhesion signaling","volume":"132","author":"Rahikainen","year":"2019","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109616_bib43","doi-asserted-by":"crossref","first-page":"e3000253","DOI":"10.1371\/journal.pbio.3000253","article-title":"Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice","volume":"17","author":"Rojek","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib44","doi-asserted-by":"crossref","DOI":"10.1002\/cpps.51","article-title":"BioID: A Screen for Protein-Protein Interactions","volume":"91","author":"Roux","year":"2018","journal-title":"Curr. Protoc. Protein Sci."},{"key":"10.1016\/j.celrep.2021.109616_bib45","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/embor.2011.5","article-title":"Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins","volume":"12","author":"Schiller","year":"2011","journal-title":"EMBO Rep."},{"key":"10.1016\/j.celrep.2021.109616_bib46","doi-asserted-by":"crossref","first-page":"a005066","DOI":"10.1101\/cshperspect.a005066","article-title":"Integrins and extracellular matrix in mechanotransduction","volume":"2","author":"Schwartz","year":"2010","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib47","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.devcel.2010.08.008","article-title":"A zyxin-mediated mechanism for actin stress fiber maintenance and repair","volume":"19","author":"Smith","year":"2010","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2021.109616_bib48","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1471-213X-1-4","article-title":"Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus","volume":"1","author":"Srinivas","year":"2001","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib49","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1167\/iovs.10-5176","article-title":"The mouse retina as an angiogenesis model","volume":"51","author":"Stahl","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.celrep.2021.109616_bib50","doi-asserted-by":"crossref","first-page":"4451","DOI":"10.1242\/dev.071381","article-title":"Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis","volume":"138","author":"Stenzel","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.celrep.2021.109616_bib51","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/ncb3402","article-title":"Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation","volume":"18","author":"Sun","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib52","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1039\/c0lc00641f","article-title":"A new micropatterning method of soft substrates reveals that different tumorigenic signals can promote or reduce cell contraction levels","volume":"11","author":"Tseng","year":"2011","journal-title":"Lab Chip"},{"key":"10.1016\/j.celrep.2021.109616_bib53","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/s10456-017-9563-8","article-title":"Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion","volume":"20","author":"Turner","year":"2017","journal-title":"Angiogenesis"},{"key":"10.1016\/j.celrep.2021.109616_bib54","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.yexcr.2005.10.030","article-title":"Angiogenesis in the mouse retina: a model system for experimental manipulation","volume":"312","author":"Uemura","year":"2006","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.celrep.2021.109616_bib55","doi-asserted-by":"crossref","first-page":"1260419","DOI":"10.1126\/science.1260419","article-title":"Proteomics. Tissue-based map of the human proteome","volume":"347","author":"Uhl\u00e9n","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.celrep.2021.109616_bib56","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.cell.2006.02.045","article-title":"A Rich1\/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells","volume":"125","author":"Wells","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2021.109616_bib57","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1083\/jcb.201705184","article-title":"The polarity protein Angiomotin p130 controls dendritic spine maturation","volume":"217","author":"Wigerius","year":"2018","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.celrep.2021.109616_bib58","doi-asserted-by":"crossref","first-page":"6429","DOI":"10.1038\/ncomms7429","article-title":"Integrin \u03b21 controls VE-cadherin localization and blood vessel stability","volume":"6","author":"Yamamoto","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2021.109616_bib59","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.ccr.2011.02.017","article-title":"A tight junction-associated Merlin-angiomotin complex mediates Merlin\u2019s regulation of mitogenic signaling and tumor suppressive functions","volume":"19","author":"Yi","year":"2011","journal-title":"Cancer Cell"},{"key":"10.1016\/j.celrep.2021.109616_bib60","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1242\/jcs.066183","article-title":"The switchable integrin adhesome","volume":"123","author":"Zaidel-Bar","year":"2010","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2021.109616_bib61","doi-asserted-by":"crossref","first-page":"10145","DOI":"10.18632\/oncotarget.14358","article-title":"Angiomotin regulates prostate cancer cell proliferation by signaling through the Hippo-YAP pathway","volume":"8","author":"Zeng","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.celrep.2021.109616_bib62","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1091\/mbc.8.8.1415","article-title":"Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction","volume":"8","author":"Zhang","year":"1997","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.celrep.2021.109616_bib63","doi-asserted-by":"crossref","first-page":"30622","DOI":"10.1038\/srep30622","article-title":"Angiomotin like-1 is a novel component of the N-cadherin complex affecting endothelial\/pericyte interaction in normal and tumor angiogenesis","volume":"6","author":"Zheng","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2021.109616_bib64","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1083\/jcb.141.2.539","article-title":"Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly","volume":"141","author":"Zhong","year":"1998","journal-title":"J.\u00a0Cell Biol."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124721010548?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124721010548?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T11:26:14Z","timestamp":1761909974000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124721010548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":64,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S2211124721010548"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2021.109616","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.740700361.793588701","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.740700361.793589318","asserted-by":"object"}],"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.01.14.426638","asserted-by":"object"}]},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Amot\/integrin protein complex transmits mechanical forces required for vascular expansion","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2021.109616","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"109616"}}