{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:13:12Z","timestamp":1790298792799,"version":"4.1.0"},"reference-count":88,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T00:00:00Z","timestamp":1634515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"NIAID","doi-asserted-by":"publisher","award":["AI100527"],"award-info":[{"award-number":["AI100527"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"NIAID","doi-asserted-by":"publisher","award":["AI42767"],"award-info":[{"award-number":["AI42767"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008893","name":"University of Iowa","doi-asserted-by":"publisher","award":["A125446"],"award-info":[{"award-number":["A125446"]}],"id":[{"id":"10.13039\/100008893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008893","name":"University of Iowa","doi-asserted-by":"publisher","award":["A127481"],"award-info":[{"award-number":["A127481"]}],"id":[{"id":"10.13039\/100008893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008893","name":"University of Iowa","doi-asserted-by":"publisher","award":["AI114543"],"award-info":[{"award-number":["AI114543"]}],"id":[{"id":"10.13039\/100008893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008893","name":"University of Iowa","doi-asserted-by":"publisher","award":["AI985515"],"award-info":[{"award-number":["AI985515"]}],"id":[{"id":"10.13039\/100008893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008893","name":"University of Iowa","doi-asserted-by":"publisher","award":["GM134880"],"award-info":[{"award-number":["GM134880"]}],"id":[{"id":"10.13039\/100008893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008893","name":"University of Iowa","doi-asserted-by":"publisher","award":["T32 AI007511"],"award-info":[{"award-number":["T32 AI007511"]}],"id":[{"id":"10.13039\/100008893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008893","name":"University of Iowa","doi-asserted-by":"publisher","award":["T32 HL007"],"award-info":[{"award-number":["T32 HL007"]}],"id":[{"id":"10.13039\/100008893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 CA086862"],"award-info":[{"award-number":["P30 CA086862"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.celrep.2021.109956","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T01:48:48Z","timestamp":1635904128000},"page":"109956","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["Expeditious recruitment of circulating memory CD8 T\u00a0cells to the liver facilitates control of malaria"],"prefix":"10.1016","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7641-7043","authenticated-orcid":false,"given":"Mitchell N.","family":"Lefebvre","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fionna A.","family":"Surette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott M.","family":"Anthony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Vijay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3107-3961","authenticated-orcid":false,"given":"Isaac J.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lecia L.","family":"Pewe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1940-2619","authenticated-orcid":false,"given":"Lisa S.","family":"Hancox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalija","family":"Van Braeckel-Budimir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"van de Wall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2774-0319","authenticated-orcid":false,"given":"Stina L.","family":"Urban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madison R.","family":"Mix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samarchith P.","family":"Kurup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir P.","family":"Badovinac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1429-0796","authenticated-orcid":false,"given":"Noah S.","family":"Butler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7266-2802","authenticated-orcid":false,"given":"John T.","family":"Harty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2021.109956_bib1","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1056\/NEJMoa1208394","article-title":"A phase 3 trial of RTS,S\/AS01 malaria vaccine in African infants","volume":"367","author":"Agnandji","year":"2012","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.celrep.2021.109956_bib2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1126\/science.1254803","article-title":"T cell memory. Skin-resident memory CD8+ T\u00a0cells trigger a state of tissue-wide pathogen alert","volume":"346","author":"Ariotti","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.celrep.2021.109956_bib3","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/nm1257","article-title":"Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination","volume":"11","author":"Badovinac","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.celrep.2021.109956_bib4","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/s41590-017-0029-3","article-title":"Intravital mucosal imaging of CD8+ resident memory T\u00a0cells shows tissue-autonomous recall responses that amplify secondary memory","volume":"19","author":"Beura","year":"2018","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib5","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.4049\/jimmunol.1801613","article-title":"ARTC2.2\/P2RX7 Signaling during Cell Isolation Distorts Function and Quantification of Tissue-Resident CD8+ T Cell and Invariant NKT Subsets","volume":"202","author":"Borges da Silva","year":"2019","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib6","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/nbt.3519","article-title":"Near-optimal probabilistic RNA-seq quantification","volume":"34","author":"Bray","year":"2016","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.celrep.2021.109956_bib7","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1038\/cti.2016.62","article-title":"Infiltrating monocytes in liver injury and repair","volume":"5","author":"Brempelis","year":"2016","journal-title":"Clin. Transl. Immunology"},{"key":"10.1016\/j.celrep.2021.109956_bib8","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.4049\/jimmunol.0903529","article-title":"Differential effector pathways regulate memory CD8 T\u00a0cell immunity against Plasmodium berghei versus P. yoelii sporozoites","volume":"184","author":"Butler","year":"2010","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib9","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1002\/eji.201646837","article-title":"CD69: from activation marker to metabolic gatekeeper","volume":"47","author":"Cibri\u00e1n","year":"2017","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib10","doi-asserted-by":"crossref","first-page":"9090","DOI":"10.1073\/pnas.1303858110","article-title":"In\u00a0vivo imaging of CD8+ T\u00a0cell-mediated elimination of malaria liver stages","volume":"110","author":"Cockburn","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2021.109956_bib11","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1128\/IAI.01500-13","article-title":"CD8+ T\u00a0cells eliminate liver-stage Plasmodium berghei parasites without detectable bystander effect","volume":"82","author":"Cockburn","year":"2014","journal-title":"Infect. Immun."},{"key":"10.1016\/j.celrep.2021.109956_bib12","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1034\/j.1600-0528.2002.017407.x","article-title":"Innate defenses in the liver during Listeria infection","volume":"174","author":"Cousens","year":"2000","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.celrep.2021.109956_bib13","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.cell.2016.07.055","article-title":"Malaria: Biology and Disease","volume":"167","author":"Cowman","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2021.109956_bib14","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jhep.2011.12.035","article-title":"Migration of lymphocytes into hepatic sinusoids","volume":"57","author":"Crispe","year":"2012","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.celrep.2021.109956_bib15","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1146\/annurev-immunol-032713-120220","article-title":"Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease","volume":"32","author":"Crompton","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib16","doi-asserted-by":"crossref","first-page":"e1006569","DOI":"10.1371\/journal.ppat.1006569","article-title":"Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T\u00a0cells","volume":"13","author":"Danahy","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2021.109956_bib17","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/s12026-014-8525-0","article-title":"Correlates of protective immunity following whole sporozoite vaccination against malaria","volume":"59","author":"Doll","year":"2014","journal-title":"Immunol. Res."},{"key":"10.1016\/j.celrep.2021.109956_bib18","doi-asserted-by":"crossref","first-page":"4253","DOI":"10.4049\/jimmunol.1600155","article-title":"Discriminating Protective from Nonprotective Plasmodium-Specific CD8+ T Cell Responses","volume":"196","author":"Doll","year":"2016","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib19","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.immuni.2016.08.011","article-title":"Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection","volume":"45","author":"Fernandez-Ruiz","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2021.109956_bib20","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/j.immuni.2016.10.018","article-title":"The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8\u00a0T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis","volume":"45","author":"Gerlach","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2021.109956_bib21","doi-asserted-by":"crossref","first-page":"8565","DOI":"10.3390\/ijms21228565","article-title":"Resident Memory T Cells and Their Role within the Liver","volume":"21","author":"Ghilas","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.celrep.2021.109956_bib22","doi-asserted-by":"crossref","first-page":"eaap9128","DOI":"10.1126\/scitranslmed.aap9128","article-title":"Prime and target immunization protects against liver-stage malaria in mice","volume":"10","author":"Gola","year":"2018","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.celrep.2021.109956_bib23","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1146\/annurev-immunol-032713-120145","article-title":"Chemokines and chemokine receptors: positioning cells for host defense and immunity","volume":"32","author":"Griffith","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib24","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.cell.2015.03.005","article-title":"Immunosurveillance of the liver by intravascular effector CD8(+) T\u00a0cells","volume":"161","author":"Guidotti","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2021.109956_bib25","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1038\/nprot.2006.61","article-title":"Generation of T-cell receptor retrogenic mice","volume":"1","author":"Holst","year":"2006","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2021.109956_bib26","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.celrep.2018.08.094","article-title":"CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver","volume":"25","author":"Holz","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2021.109956_bib27","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1128\/iai.58.3.619-624.1990","article-title":"Mortality and bacteriology of sepsis following cecal ligation and puncture in aged mice","volume":"58","author":"Hyde","year":"1990","journal-title":"Infect. Immun."},{"key":"10.1016\/j.celrep.2021.109956_bib28","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/nm.4110","article-title":"Protection against malaria at 1 year and immune correlates following PfSPZ vaccination","volume":"22","author":"Ishizuka","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.celrep.2021.109956_bib29","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.immuni.2018.02.010","article-title":"Understanding Subset Diversity in T Cell Memory","volume":"48","author":"Jameson","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2021.109956_bib30","doi-asserted-by":"crossref","first-page":"e1007405","DOI":"10.1371\/journal.ppat.1007405","article-title":"Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections","volume":"14","author":"Jensen","year":"2018","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2021.109956_bib31","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.immuni.2020.02.003","article-title":"Worry and FRET: ROS Production Leads to Fluorochrome Tandem Degradation and impairs Interpretation of Flow Cytometric Results","volume":"52","author":"Jensen","year":"2020","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2021.109956_bib32","doi-asserted-by":"crossref","first-page":"5222","DOI":"10.4049\/jimmunol.172.9.5222","article-title":"Passive and active mechanisms trap activated CD8+ T\u00a0cells in the liver","volume":"172","author":"John","year":"2004","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib33","doi-asserted-by":"crossref","first-page":"338","DOI":"10.4269\/ajtmh.17-1014","article-title":"Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults","volume":"99","author":"Jongo","year":"2018","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.celrep.2021.109956_bib34","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/cmi.2015.104","article-title":"Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies","volume":"13","author":"Ju","year":"2016","journal-title":"Cell. Mol. Immunol."},{"issue":"80","key":"10.1016\/j.celrep.2021.109956_bib35","article-title":"Parabiosis in mice: a detailed protocol","author":"Kamran","year":"2013","journal-title":"J.\u00a0Vis. Exp."},{"key":"10.1016\/j.celrep.2021.109956_bib36","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.immuni.2008.05.011","article-title":"The chemokine receptor CCR5 plays a key role in the early memory CD8+ T\u00a0cell response to respiratory virus infections","volume":"29","author":"Kohlmeier","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2021.109956_bib37","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S1286-4579(00)00296-3","article-title":"The macrophage receptor MARCO","volume":"2","author":"Kraal","year":"2000","journal-title":"Microbes Infect."},{"key":"10.1016\/j.celrep.2021.109956_bib38","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/nature05361","article-title":"The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites","volume":"444","author":"Kumar","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109956_bib39","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.chom.2019.02.014","article-title":"Monocyte-Derived CD11c(+) Cells Acquire Plasmodium from Hepatocytes to Prime CD8\u00a0T Cell Immunity to Liver-Stage Malaria","volume":"25","author":"Kurup","year":"2019","journal-title":"Cell Host Microbe."},{"key":"10.1016\/j.celrep.2021.109956_bib40","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/s41577-019-0158-z","article-title":"T cell-mediated immunity to malaria","volume":"19","author":"Kurup","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib41","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2104407118","article-title":"Circulating immunity protects the female reproductive tract from Chlamydia infection","volume":"118","author":"Labuda","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2021.109956_bib42","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1080\/21645515.2019.1669415","article-title":"RTS,S\/AS01 vaccine (Mosquirix\u2122): an overview","volume":"16","author":"Laurens","year":"2020","journal-title":"Hum. Vaccin. Immunother."},{"key":"10.1016\/j.celrep.2021.109956_bib43","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jhep.2007.12.005","article-title":"Leukocyte adhesion in the liver: distinct adhesion paradigm from other organs","volume":"48","author":"Lee","year":"2008","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.celrep.2021.109956_bib44","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/ni.1855","article-title":"An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells","volume":"11","author":"Lee","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib45","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.pt.2019.11.004","article-title":"You Shall Not Pass: Memory CD8\u00a0T Cells in Liver-Stage Malaria","volume":"36","author":"Lefebvre","year":"2020","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.celrep.2021.109956_bib46","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nm.3424","article-title":"Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection","volume":"20","author":"Liehl","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.celrep.2021.109956_bib47","first-page":"3239","article-title":"Differences in dendritic cells stimulated in\u00a0vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand","volume":"60","author":"Mach","year":"2000","journal-title":"Cancer Res."},{"key":"10.1016\/j.celrep.2021.109956_bib48","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1126\/science.aad2035","article-title":"Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes","volume":"352","author":"Mackay","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.celrep.2021.109956_bib49","doi-asserted-by":"crossref","first-page":"3300","DOI":"10.1073\/pnas.88.8.3300","article-title":"Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein","volume":"88","author":"Malik","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2021.109956_bib50","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.3389\/fimmu.2018.02692","article-title":"Defining Memory CD8\u00a0T Cell","volume":"9","author":"Martin","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib51","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1146\/annurev-immunol-042617-053214","article-title":"Tissue-Resident T Cells and Other Resident Leukocytes","volume":"37","author":"Masopust","year":"2019","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib52","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nri3787","article-title":"Type I interferons in infectious disease","volume":"15","author":"McNab","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib53","doi-asserted-by":"crossref","first-page":"eaaj1996","DOI":"10.1126\/sciimmunol.aaj1996","article-title":"Up-regulation of LFA-1 allows liver-resident memory T\u00a0cells to patrol and remain in the hepatic sinusoids","volume":"2","author":"McNamara","year":"2017","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib54","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.4049\/jimmunol.163.6.3202","article-title":"Selective retention of activated CD8+ T\u00a0cells by the normal liver","volume":"163","author":"Mehal","year":"1999","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib55","doi-asserted-by":"crossref","first-page":"6713","DOI":"10.4049\/jimmunol.180.10.6713","article-title":"The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor","volume":"180","author":"Meiser","year":"2008","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib56","doi-asserted-by":"crossref","first-page":"3853","DOI":"10.1182\/blood.V100.12.3853","article-title":"Leukocyte extravasation: chemokine transport and presentation by the endothelium","volume":"100","author":"Middleton","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.celrep.2021.109956_bib57","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1007\/s00018-015-1835-0","article-title":"Molecular mechanisms of CD8(+) T\u00a0cell trafficking and localization","volume":"72","author":"Nolz","year":"2015","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.celrep.2021.109956_bib58","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/216160a0","article-title":"Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei","volume":"216","author":"Nussenzweig","year":"1967","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109956_bib59","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.4049\/jimmunol.1800740","article-title":"Prime-and-Trap Malaria Vaccination To Generate Protective CD8+ Liver-Resident Memory T Cells","volume":"201","author":"Olsen","year":"2018","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib60","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1016\/j.immuni.2013.05.009","article-title":"Effector-like CD8+ T\u00a0cells in the memory population mediate potent protective immunity","volume":"38","author":"Olson","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2021.109956_bib61","doi-asserted-by":"crossref","first-page":"e1007633","DOI":"10.1371\/journal.ppat.1007633","article-title":"Central memory CD8+ T\u00a0cells become CD69+ tissue-residents during viral skin infection independent of CD62L-mediated lymph node surveillance","volume":"15","author":"Osborn","year":"2019","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2021.109956_bib62","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1600-065X.2008.00671.x","article-title":"Protective CD8 T\u00a0cells against Plasmodium liver stages: immunobiology of an \u2018unnatural\u2019 immune response","volume":"225","author":"Overstreet","year":"2008","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.celrep.2021.109956_bib63","doi-asserted-by":"crossref","first-page":"831","DOI":"10.2307\/3281779","article-title":"Simple centrifugation method for rapid separation of sporozoites from mosquitoes","volume":"70","author":"Ozaki","year":"1984","journal-title":"J.\u00a0Parasitol."},{"key":"10.1016\/j.celrep.2021.109956_bib64","first-page":"H1955","article-title":"Regional differences in constitutive and induced ICAM-1 expression in\u00a0vivo","volume":"269","author":"Pan\u00e9s","year":"1995","journal-title":"Am. J. Physiol."},{"issue":"157","key":"10.1016\/j.celrep.2021.109956_bib65","article-title":"Murine Precision-Cut Liver Slices as an Ex\u00a0Vivo Model of Liver Biology","author":"Pearen","year":"2020","journal-title":"J.\u00a0Vis. Exp."},{"key":"10.1016\/j.celrep.2021.109956_bib66","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/cmi.2015.96","article-title":"Liver natural killer cells: subsets and roles in liver immunity","volume":"13","author":"Peng","year":"2016","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib67","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/nm.2368","article-title":"Host-mediated regulation of superinfection in malaria","volume":"17","author":"Portugal","year":"2011","journal-title":"Nat. Med."},{"key":"10.1016\/j.celrep.2021.109956_bib68","doi-asserted-by":"crossref","first-page":"e1007057","DOI":"10.1371\/journal.ppat.1007057","article-title":"Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection","volume":"14","author":"Posfai","year":"2018","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2021.109956_bib69","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nri3169","article-title":"Living in the liver: hepatic infections","volume":"12","author":"Protzer","year":"2012","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib70","doi-asserted-by":"crossref","first-page":"7672","DOI":"10.4049\/jimmunol.0902874","article-title":"Tracking the total CD8 T\u00a0cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts","volume":"183","author":"Rai","year":"2009","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib71","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/hep.22742","article-title":"Liver biopsy","volume":"49","author":"Rockey","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.celrep.2021.109956_bib72","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/341323a0","article-title":"Cloned cytotoxic T\u00a0cells recognize an epitope in the circumsporozoite protein and protect against malaria","volume":"341","author":"Romero","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109956_bib73","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.immuni.2019.09.002","article-title":"Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity","volume":"51","author":"Sakai","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2021.109956_bib74","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.imlet.2008.11.008","article-title":"Clinical malaria vaccine development","volume":"122","author":"Sauerwein","year":"2009","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.celrep.2021.109956_bib75","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/ni.2568","article-title":"Sensing and alarm function of resident memory CD8+ T\u00a0cells","volume":"14","author":"Schenkel","year":"2013","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib76","doi-asserted-by":"crossref","first-page":"14017","DOI":"10.1073\/pnas.0805452105","article-title":"Memory CD8 T\u00a0cell responses exceeding a large but definable threshold provide long-term immunity to malaria","volume":"105","author":"Schmidt","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2021.109956_bib77","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/330664a0","article-title":"Gamma interferon, CD8+ T\u00a0cells and antibodies required for immunity to malaria sporozoites","volume":"330","author":"Schofield","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2021.109956_bib78","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9","article-title":"The Ki-67 protein: from the known and the unknown","volume":"182","author":"Scholzen","year":"2000","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.celrep.2021.109956_bib79","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1126\/science.1241800","article-title":"Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine","volume":"341","author":"Seder","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.celrep.2021.109956_bib80","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1038\/ni.2745","article-title":"Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T\u00a0cells","volume":"14","author":"Skon","year":"2013","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib81","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.immuni.2013.09.013","article-title":"Lung airway-surveilling CXCR3(hi) memory CD8(+) T\u00a0cells are critical for protection against influenza A virus","volume":"39","author":"Sl\u00fctter","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2021.109956_bib82","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1146\/annurev.iy.05.040187.001255","article-title":"The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system","volume":"5","author":"Springer","year":"1987","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib83","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.cell.2015.03.031","article-title":"Quantifying Memory CD8\u00a0T Cells Reveals Regionalization of Immunosurveillance","volume":"161","author":"Steinert","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2021.109956_bib84","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.chom.2020.04.010","article-title":"A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice","volume":"27","author":"Valencia-Hernandez","year":"2020","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2021.109956_bib85","doi-asserted-by":"crossref","first-page":"3374","DOI":"10.1016\/j.celrep.2018.08.073","article-title":"Repeated Antigen Exposure Extends the Durability of Influenza-Specific Lung-Resident Memory CD8+ T Cells and Heterosubtypic Immunity","volume":"24","author":"Van Braeckel-Budimir","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2021.109956_bib86","doi-asserted-by":"crossref","first-page":"939","DOI":"10.4049\/jimmunol.162.2.939","article-title":"Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in\u00a0vivo","volume":"162","author":"van der Laan","year":"1999","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2021.109956_bib87","doi-asserted-by":"crossref","first-page":"a025486","DOI":"10.1101\/cshperspect.a025486","article-title":"Malaria Parasite Liver Infection and Exoerythrocytic Biology","volume":"7","author":"Vaughan","year":"2017","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.celrep.2021.109956_bib88","series-title":"World Malaria Report 2020: 20 Years of Global Progress and Challenges","year":"2020"}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124721014339?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124721014339?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T11:31:41Z","timestamp":1761910301000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124721014339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":88,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S2211124721014339"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2021.109956","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expeditious recruitment of circulating memory CD8 T\u00a0cells to the liver facilitates control of malaria","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2021.109956","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"109956"}}