{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T11:24:33Z","timestamp":1790767473816,"version":"4.1.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T00:00:00Z","timestamp":1649894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31721003"],"award-info":[{"award-number":["31721003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31871448"],"award-info":[{"award-number":["31871448"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81630035"],"award-info":[{"award-number":["81630035"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81804129"],"award-info":[{"award-number":["81804129"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871213"],"award-info":[{"award-number":["81871213"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82022027"],"award-info":[{"award-number":["82022027"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2017YFA0102602"],"award-info":[{"award-number":["2017YFA0102602"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["19JC1415300"],"award-info":[{"award-number":["19JC1415300"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["21JC1405500"],"award-info":[{"award-number":["21JC1405500"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.celrep.2022.110784","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:20:41Z","timestamp":1651796441000},"page":"110784","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos"],"prefix":"10.1016","volume":"39","author":[{"given":"Dandan","family":"Bai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanping","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhe","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuisheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yalin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiqing","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingdong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxiao","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingling","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochen","family":"Kou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaoxin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cizhong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1041-3928","authenticated-orcid":false,"given":"Shaorong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2022.110784_bib1","doi-asserted-by":"crossref","first-page":"11296","DOI":"10.1073\/pnas.1310156110","article-title":"Molecular basis for chromatin binding and regulation of MLL5","volume":"110","author":"Ali","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U\u00a0S\u00a0A."},{"key":"10.1016\/j.celrep.2022.110784_bib2","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.3390\/ijms20112837","article-title":"The role of epigenetics in placental development and the etiology of preeclampsia","volume":"20","author":"Apicella","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.celrep.2022.110784_bib3","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.ydbio.2006.05.003","article-title":"Loss of the maternal imprint in Dnmt3L(mat-\/-) mice leads to a differentiation defect in the extraembryonic tissue","volume":"297","author":"Arima","year":"2006","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2022.110784_bib4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.lfs.2019.05.032","article-title":"Pharmacological modulation of autophagy as a novel potential target in the successful implementation of in\u00a0vitro fertilization","volume":"229","author":"Bai","year":"2019","journal-title":"Life Sci."},{"key":"10.1016\/j.celrep.2022.110784_bib5","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.cell.2014.06.027","article-title":"H3K4me3 breadth is linked to cell identity and transcriptional consistency","volume":"158","author":"Benayoun","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2022.110784_bib6","doi-asserted-by":"crossref","first-page":"3457","DOI":"10.1210\/en.2011-1921","article-title":"Impaired placental nutrient transport in mice generated by in\u00a0vitro fertilization","volume":"153","author":"Bloise","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.celrep.2022.110784_bib7","doi-asserted-by":"crossref","first-page":"6033","DOI":"10.1038\/ncomms7033","article-title":"An ultra-low-input native ChIP-seq protocol for genome-wide profiling of rare cell populations","volume":"6","author":"Brind'Amour","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2022.110784_bib8","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1095\/biolreprod.113.113142","article-title":"Generalized disturbance of DNA methylation in the uterine decidua in the CBA\/J x DBA\/2 mouse model of pregnancy failure","volume":"89","author":"Brown","year":"2013","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.celrep.2022.110784_bib9","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.rbmo.2019.11.001","article-title":"Factors related to early spontaneous miscarriage during IVF\/ICSI treatment: an analysis of 21,485 clinical pregnancies","volume":"40","author":"Bu","year":"2020","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.celrep.2022.110784_bib10","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1038\/ng.3385","article-title":"Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes","volume":"47","author":"Chen","year":"2015","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2022.110784_bib11","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1146\/annurev-genom-091212-153441","article-title":"Phenotypic outcomes of imprinted gene models in mice: elucidation of pre- and postnatal functions of imprinted genes","volume":"15","author":"Cleaton","year":"2014","journal-title":"Annu. Rev. Genom Hum. G"},{"key":"10.1016\/j.celrep.2022.110784_bib12","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1038\/nature19360","article-title":"Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition","volume":"537","author":"Dahl","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.110784_bib13","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1095\/biolreprod.113.114785","article-title":"In\u00a0vitro culture increases the frequency of stochastic epigenetic errors at imprinted genes in placental tissues from mouse concepti produced through assisted reproductive technologies","volume":"90","author":"de Waal","year":"2014","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.celrep.2022.110784_bib14","first-page":"6975","article-title":"The cumulative effect of assisted reproduction procedures on placental development and epigenetic perturbations in a mouse model","volume":"24","author":"de Waal","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2022.110784_bib15","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1002\/mrd.22970","article-title":"Long term effects of ART: what do animals tell us?","volume":"85","author":"Duranthon","year":"2018","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.celrep.2022.110784_bib16","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/nmeth.1906","article-title":"ChromHMM: automating chromatin-state discovery and characterization","volume":"9","author":"Ernst","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2022.110784_bib17","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1038\/nprot.2017.124","article-title":"Chromatin-state discovery and genome annotation with ChromHMM","volume":"12","author":"Ernst","year":"2017","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2022.110784_bib18","doi-asserted-by":"crossref","first-page":"092","DOI":"10.1055\/s-0032-1307417","article-title":"Role of ART in imprinting disorders","volume":"30","author":"Eroglu","year":"2012","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.celrep.2022.110784_bib19","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.rbmo.2013.10.013","article-title":"Health outcomes of children born after IVF\/ICSI: a review of current expert opinion and literature","volume":"28","author":"Fauser","year":"2014","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.celrep.2022.110784_bib20","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.pbiomolbio.2010.11.005","article-title":"Imprinted genes and the epigenetic regulation of placental phenotype","volume":"106","author":"Fowden","year":"2011","journal-title":"Prog. Biophys. Mol. Bio"},{"key":"10.1016\/j.celrep.2022.110784_bib21","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.fertnstert.2016.12.007","article-title":"Cardiovascular and metabolic profiles of offspring conceived by assisted reproductive technologies: a systematic review and meta-analysis","volume":"107","author":"Guo","year":"2017","journal-title":"Fertil. Steril"},{"key":"10.1016\/j.celrep.2022.110784_bib22","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1186\/s13059-019-1833-x","article-title":"Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues","volume":"20","author":"Hanna","year":"2019","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2022.110784_bib23","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev-animal-021419-084010","article-title":"Implications of assisted reproductive technologies for pregnancy outcomes in mammals","volume":"8","author":"Hansen","year":"2020","journal-title":"Annu. Rev. Anim. Biosci."},{"key":"10.1016\/j.celrep.2022.110784_bib24","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3389\/fphys.2016.00028","article-title":"Placental adaptation: what can we learn from birthweight:placental weight ratio?","volume":"7","author":"Hayward","year":"2016","journal-title":"Front. Physiol."},{"key":"10.1016\/j.celrep.2022.110784_bib25","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/s12958-018-0390-6","article-title":"Influencing factors of pregnancy loss and survival probability of clinical pregnancies conceived through assisted reproductive technology","volume":"16","author":"Hu","year":"2018","journal-title":"Reprod. Biol. Endocrin"},{"key":"10.1016\/j.celrep.2022.110784_bib26","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1095\/biolreprod.114.122762","article-title":"Impairment of preimplantation porcine embryo development by histone demethylase KDM5B knockdown through disturbance of bivalent H3K4me3-H3K27me3 modifications","volume":"92","author":"Huang","year":"2015","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.celrep.2022.110784_bib27","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1038\/nature23262","article-title":"Maternal H3K27me3 controls DNA methylation-independent imprinting","volume":"547","author":"Inoue","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.110784_bib28","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.neures.2018.09.010","article-title":"Molecular mechanisms of H3K27me3 and H3K4me3 in retinal development","volume":"138","author":"Iwagawa","year":"2019","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.celrep.2022.110784_bib29","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ogc.2019.10.002","article-title":"Placental implantation disorders","volume":"47","author":"Jauniaux","year":"2020","journal-title":"Obstet. Gyn Clin. N. Am."},{"key":"10.1016\/j.celrep.2022.110784_bib30","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2022.110784_bib31","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.5713\/ajas.15.0762","article-title":"Rapamycin influences the efficiency of in\u00a0vitro fertilization and development in the mouse: a role for autophagic activation","volume":"29","author":"Lee","year":"2016","journal-title":"Asian Austral J. Anim."},{"key":"10.1016\/j.celrep.2022.110784_bib32","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1093\/bioinformatics\/btp324","article-title":"Fast and accurate short read alignment with Burrows-Wheeler transform","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2022.110784_bib33","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"featureCounts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"30","author":"Liao","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2022.110784_bib34","first-page":"430","article-title":"Dynamic patterns of H3K4me3, H3K27me3, and Nanog during rabbit embryo development","volume":"11","author":"Liu","year":"2019","journal-title":"Am. J. Transl Res."},{"key":"10.1016\/j.celrep.2022.110784_bib35","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/nature19362","article-title":"Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos","volume":"537","author":"Liu","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.110784_bib36","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2022.110784_bib37","doi-asserted-by":"crossref","first-page":"e35368","DOI":"10.7554\/eLife.35368","article-title":"Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila","volume":"7","author":"Ma","year":"2018","journal-title":"Elife"},{"key":"10.1016\/j.celrep.2022.110784_bib38","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1182\/blood-2008-02-142638","article-title":"Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog Mll5","volume":"113","author":"Madan","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.celrep.2022.110784_bib39","doi-asserted-by":"crossref","first-page":"e1001356","DOI":"10.1371\/journal.pmed.1001356","article-title":"National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys","volume":"9","author":"Mascarenhas","year":"2012","journal-title":"PLoS Med."},{"key":"10.1016\/j.celrep.2022.110784_bib40","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s00251-019-01124-x","article-title":"Methylation of H3K27 and H3K4 in key gene promoter regions of thymus in RA mice is involved in the abnormal development and differentiation of iNKT cells","volume":"71","author":"Meng","year":"2019","journal-title":"Immunogenetics"},{"key":"10.1016\/j.celrep.2022.110784_bib41","first-page":"110","article-title":"Interfering effects of in\u00a0vitro fertilization and vitrification on expression of Gtl2 and Dlk1 in mouse blastocysts","volume":"14","author":"Movahed","year":"2020","journal-title":"Int. J. Fertil. Steril"},{"key":"10.1016\/j.celrep.2022.110784_bib42","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.celrep.2014.10.018","article-title":"Quantitative ChIP-seq normalization reveals global modulation of the epigenome","volume":"9","author":"Orlando","year":"2014","journal-title":"Cell Rep"},{"key":"10.1016\/j.celrep.2022.110784_bib43","doi-asserted-by":"crossref","first-page":"2891","DOI":"10.1111\/febs.15219","article-title":"Broad domains of histone H3 lysine 4 trimethylation in transcriptional regulation and disease","volume":"287","author":"Park","year":"2020","journal-title":"Febs J."},{"key":"10.1016\/j.celrep.2022.110784_bib44","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nprot.2014.006","article-title":"Full-length RNA-seq from single cells using Smart-seq2","volume":"9","author":"Picelli","year":"2014","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2022.110784_bib45","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1093\/bioinformatics\/btq033","article-title":"BEDTools: a flexible suite of utilities for comparing genomic features","volume":"26","author":"Quinlan","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2022.110784_bib46","doi-asserted-by":"crossref","first-page":"W160","DOI":"10.1093\/nar\/gkw257","article-title":"deepTools2: a next generation web server for deep-sequencing data analysis","volume":"44","author":"Ramirez","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2022.110784_bib47","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","article-title":"edgeR: a Bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2022.110784_bib48","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1073\/pnas.0807136106","article-title":"MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation","volume":"106","author":"Sebastian","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U\u00a0S\u00a0A."},{"key":"10.1016\/j.celrep.2022.110784_bib49","doi-asserted-by":"crossref","first-page":"17829","DOI":"10.1038\/srep17829","article-title":"Induction of autophagy improves embryo viability in cloned mouse embryos","volume":"5","author":"Shen","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2022.110784_bib50","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1007\/s00404-018-4904-4","article-title":"Reply to letter to the editor","volume":"298","author":"Shinar","year":"2018","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.celrep.2022.110784_bib51","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1159\/000090843","article-title":"Regulation of growth and metabolism by imprinted genes","volume":"113","author":"Smith","year":"2006","journal-title":"Cytogenet. Genome Res."},{"key":"10.1016\/j.celrep.2022.110784_bib52","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/molehr\/gaw028","article-title":"Dynamic integrated analysis of DNA methylation and gene expression profiles in in\u00a0vivo and in\u00a0vitro fertilized mouse post-implantation extraembryonic and placental tissues","volume":"22","author":"Tan","year":"2016","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.celrep.2022.110784_bib53","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/nprot.2009.236","article-title":"RNA-Seq analysis to capture the transcriptome landscape of a single cell","volume":"5","author":"Tang","year":"2010","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2022.110784_bib54","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/nmeth.1315","article-title":"mRNA-Seq whole-transcriptome analysis of a single cell","volume":"6","author":"Tang","year":"2009","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2022.110784_bib55","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ydbio.2016.08.014","article-title":"Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta","volume":"418","author":"Tunster","year":"2016","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2022.110784_bib56","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.clinbiochem.2018.03.012","article-title":"Fertility and infertility: definition and epidemiology","volume":"62","author":"Vander Borght","year":"2018","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.celrep.2022.110784_bib57","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.ceb.2012.03.009","article-title":"Bivalent histone modifications in early embryogenesis","volume":"24","author":"Vastenhouw","year":"2012","journal-title":"Curr. Opin. Cell Biol"},{"key":"10.1016\/j.celrep.2022.110784_bib58","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s40659-015-0059-y","article-title":"In\u00a0vitro fertilization (IVF) in mammals: epigenetic and developmental alterations. Scientific and bioethical implications for IVF in humans","volume":"48","author":"Ventura-Junca","year":"2015","journal-title":"Biol. Res."},{"key":"10.1016\/j.celrep.2022.110784_bib59","first-page":"23","article-title":"In\u00a0vitro fertilization technology and child health","volume":"117","author":"von Wolff","year":"2020","journal-title":"Dtsch Arztebl Int."},{"key":"10.1016\/j.celrep.2022.110784_bib60","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/s41588-019-0545-1","article-title":"Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency","volume":"52","author":"Xiang","year":"2020","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2022.110784_bib61","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/s41422-018-0010-1","article-title":"Silencing of developmental genes by H3K27me3 and DNA methylation reflects the discrepant plasticity of embryonic and extraembryonic lineages","volume":"28","author":"Yang","year":"2018","journal-title":"Cell Res"},{"key":"10.1016\/j.celrep.2022.110784_bib62","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1741-7015-10-26","article-title":"Insufficient maintenance DNA methylation is associated with abnormal embryonic development","volume":"10","author":"Yin","year":"2012","journal-title":"Bmc Med."},{"key":"10.1016\/j.celrep.2022.110784_bib63","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1093\/humrep\/dev024","article-title":"A comparison of biochemical pregnancy rates between women who underwent IVF and fertile controls who conceived spontaneously","volume":"30","author":"Zeadna","year":"2015","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.celrep.2022.110784_bib64","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/nature19361","article-title":"Allelic reprogramming of the histone modification H3K4me3 in early mammalian development","volume":"537","author":"Zhang","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.110784_bib65","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1007\/s00018-017-2470-8","article-title":"MLL5 (KMT2E): structure, function, and clinical relevance","volume":"74","author":"Zhang","year":"2017","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.celrep.2022.110784_bib66","doi-asserted-by":"crossref","first-page":"R137","DOI":"10.1186\/gb-2008-9-9-r137","article-title":"Model-based analysis of ChIP-seq (MACS)","volume":"9","author":"Zhang","year":"2008","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2022.110784_bib67","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1038\/s41467-019-09234-6","article-title":"Metascape provides a biologist-oriented resource for the analysis of systems-level datasets","volume":"10","author":"Zhou","year":"2019","journal-title":"Nat. Commun."}],"updated-by":[{"DOI":"10.1016\/j.celrep.2026.117585","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000}}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124722005514?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124722005514?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T11:41:37Z","timestamp":1761910897000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124722005514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":67,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S2211124722005514"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2022.110784","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2022.110784","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"110784"}}