{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T07:07:44Z","timestamp":1773644864339,"version":"3.50.1"},"reference-count":58,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T00:00:00Z","timestamp":1664236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ISF 1466\/18"],"award-info":[{"award-number":["ISF 1466\/18"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI163011"],"award-info":[{"award-number":["R01AI163011"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL137709"],"award-info":[{"award-number":["R01HL137709"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R35GM137905"],"award-info":[{"award-number":["R35GM137905"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011643","name":"Blavatnik Family Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011643","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000854","name":"Human Frontier Science Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000854","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004375","name":"Tel Aviv University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004375","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006245","name":"Ministry of Science and Technology, Israel","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006245","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.celrep.2022.111512","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T03:50:00Z","timestamp":1664337000000},"page":"111512","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Reduced B cell antigenicity of Omicron lowers host serologic response"],"prefix":"10.1016","volume":"41","author":[{"given":"J\u00e9r\u00f4me","family":"Tubiana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yufei","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haim J.","family":"Wolfson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Schneidman-Duhovny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2022.111512_bib1","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.cels.2019.03.006","article-title":"End-to-end differentiable learning of protein structure","volume":"8","author":"AlQuraishi","year":"2019","journal-title":"Cell Syst."},{"key":"10.1016\/j.celrep.2022.111512_bib2","first-page":"384","article-title":"Denaturization of allergen P: effect on allergenicity, antigenicity and immunogenicity","volume":"42","author":"Anfosso","year":"1979","journal-title":"Ann. Allergy"},{"key":"10.1016\/j.celrep.2022.111512_bib3","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.it.2018.04.008","article-title":"Understanding and manipulating viral immunity: antibody immunodominance enters center stage","volume":"39","author":"Angeletti","year":"2018","journal-title":"Trends Immunol."},{"key":"10.1016\/j.celrep.2022.111512_bib4","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1126\/science.abj8754","article-title":"Accurate prediction of protein structures and interactions using a three-track neural network","volume":"373","author":"Baek","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.celrep.2022.111512_bib5","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/s41586-020-2852-1","article-title":"SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies","volume":"588","author":"Barnes","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.111512_bib6","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/s41586-021-04386-2","article-title":"Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift","volume":"602","author":"Cameroni","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.111512_bib7","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1093\/bioinformatics\/btq007","article-title":"PyRosetta: a script-based interface for implementing molecular modeling algorithms using Rosetta","volume":"26","author":"Chaudhury","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2022.111512_bib8","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.immuni.2011.10.018","article-title":"Th17 cells mediate clade-specific, serotype-independent mucosal immunity","volume":"35","author":"Chen","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2022.111512_bib9","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.sbi.2010.08.001","article-title":"Unmet challenges of structural genomics","volume":"20","author":"Chruszcz","year":"2010","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.celrep.2022.111512_bib10","doi-asserted-by":"crossref","first-page":"e0178847","DOI":"10.1371\/journal.pone.0178847","article-title":"Differential Th17 response induced by the two clades of the pandemic ST258 Klebsiella pneumoniae clonal lineages producing KPC-type carbapenemase","volume":"12","author":"Clemente","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.celrep.2022.111512_bib11","doi-asserted-by":"crossref","first-page":"032601","DOI":"10.1088\/1361-6633\/aa9965","article-title":"Inverse statistical physics of protein sequences: a key issues review","volume":"81","author":"Cocco","year":"2018","journal-title":"Rep. Prog. Phys."},{"key":"10.1016\/j.celrep.2022.111512_bib12","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1056\/NEJMc2119270","article-title":"Effectiveness of BNT162b2 vaccine against omicron variant in South Africa","volume":"386","author":"Collie","year":"2021","journal-title":"N.\u00a0Engl. J. Med. Overseas. Ed."},{"key":"10.1016\/j.celrep.2022.111512_bib13","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.1093\/molbev\/msab036","article-title":"The heterogeneous landscape and early evolution of pathogen-associated CpG dinucleotides in SARS-CoV-2","volume":"38","author":"Di Gioacchino","year":"2021","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.celrep.2022.111512_bib14","doi-asserted-by":"crossref","first-page":"100529","DOI":"10.1016\/j.xcrm.2022.100529","article-title":"mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 Omicron variant","volume":"3","author":"Edara","year":"2022","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.celrep.2022.111512_bib15","doi-asserted-by":"crossref","first-page":"e1009453","DOI":"10.1371\/journal.ppat.1009453","article-title":"A human coronavirus evolves antigenically to escape antibody immunity","volume":"17","author":"Eguia","year":"2021","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2022.111512_bib16","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/s41586-021-03207-w","article-title":"Evolution of antibody immunity to SARS-CoV-2","volume":"591","author":"Gaebler","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.111512_bib17","article-title":"mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits comparable B cell expansion, neutralizing antibodies and protection against Omicron","author":"Gagne","year":"2022","journal-title":"bioRxiv"},{"key":"10.1016\/j.celrep.2022.111512_bib18","doi-asserted-by":"crossref","first-page":"veac021","DOI":"10.1093\/ve\/veac021","article-title":"An antibody-escape estimator for mutations to the SARS-CoV-2 receptor-binding domain","volume":"8","author":"Greaney","year":"2022","journal-title":"Virus Evol."},{"key":"10.1016\/j.celrep.2022.111512_bib19","doi-asserted-by":"crossref","first-page":"e1010248","DOI":"10.1371\/journal.ppat.1010248","article-title":"A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy","volume":"18","author":"Greaney","year":"2022","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2022.111512_bib20","doi-asserted-by":"crossref","first-page":"5054","DOI":"10.1073\/pnas.1402285111","article-title":"Quantitative theory of entropic forces acting on constrained nucleotide sequences applied to viruses","volume":"111","author":"Greenbaum","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2022.111512_bib21","doi-asserted-by":"crossref","first-page":"e1000079","DOI":"10.1371\/journal.ppat.1000079","article-title":"Patterns of evolution and host gene mimicry in influenza and other RNA viruses","volume":"4","author":"Greenbaum","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2022.111512_bib22","doi-asserted-by":"crossref","first-page":"e1008736","DOI":"10.1371\/journal.pcbi.1008736","article-title":"Generating functional protein variants with variational autoencoders","volume":"17","author":"Hawkins-Hooker","year":"2021","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.celrep.2022.111512_bib23","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/s41392-022-00980-6","article-title":"Spike protein of SARS-CoV-2 Omicron (B. 1.1. 529) variant has a reduced ability to induce the immune response","volume":"7","author":"He","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.celrep.2022.111512_bib24","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.cell.2021.12.032","article-title":"The Omicron variant is highly resistant against antibody-mediated neutralization\u2013implications for control of the COVID-19 pandemic","volume":"185","author":"Hoffmann","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2022.111512_bib25","series-title":"Learning Protein Structure with a Differentiable Simulator","author":"Ingraham","year":"2018"},{"key":"10.1016\/j.celrep.2022.111512_bib26","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","article-title":"Highly accurate protein structure prediction with AlphaFold","volume":"596","author":"Jumper","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.111512_bib27","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/s41586-022-04830-x","article-title":"Omicron infection enhances Delta antibody immunity in vaccinated persons","volume":"607","author":"Khan","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.111512_bib28","doi-asserted-by":"crossref","first-page":"e51230","DOI":"10.7554\/eLife.51230","article-title":"The human coronavirus HCoV-229E S-protein structure and receptor binding","volume":"8","author":"Li","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.celrep.2022.111512_bib29","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/s41586-021-04388-0","article-title":"Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2","volume":"602","author":"Liu","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.111512_bib30","doi-asserted-by":"crossref","first-page":"E1293","DOI":"10.1073\/pnas.1111471108","article-title":"Direct-coupling analysis of residue coevolution captures native contacts across many protein families","volume":"108","author":"Morcos","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2022.111512_bib31","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1093\/bioinformatics\/bty121","article-title":"Parallelization of MAFFT for large-scale multiple sequence alignments","volume":"34","author":"Nakamura","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2022.111512_bib32","doi-asserted-by":"crossref","first-page":"e59004","DOI":"10.1371\/journal.pone.0059004","article-title":"A Pareto-optimal refinement method for protein design scaffolds","volume":"8","author":"Niv\u00f3n","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.celrep.2022.111512_bib33","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1002\/pro.3943","article-title":"UCSF ChimeraX: structure visualization for researchers, educators, and developers","volume":"30","author":"Pettersen","year":"2021","journal-title":"Protein Sci."},{"key":"10.1016\/j.celrep.2022.111512_bib34","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.cell.2020.09.037","article-title":"Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology","volume":"183","author":"Piccoli","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2022.111512_bib35","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1038\/s42256-021-00310-5","article-title":"Expanding functional protein sequence spaces using generative adversarial networks","volume":"3","author":"Repecka","year":"2021","journal-title":"Nat. Mach. Intell."},{"key":"10.1016\/j.celrep.2022.111512_bib36","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.chom.2022.03.029","article-title":"SARS-CoV-2 Omicron triggers cross-reactive neutralization and Fc effector functions in previously vaccinated, but not unvaccinated, individuals","volume":"30","author":"Richardson","year":"2022","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2022.111512_bib37","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/s41592-018-0138-4","article-title":"Deep generative models of genetic variation capture the effects of mutations","volume":"15","author":"Riesselman","year":"2018","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2022.111512_bib38","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2113118119","article-title":"Epistatic models predict mutable sites in SARS-CoV-2 proteins and epitopes","volume":"119","author":"Rodriguez-Rivas","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2022.111512_bib39","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1056\/NEJMc2201607","article-title":"Neutralization profile after recovery from SARS-CoV-2 omicron infection","volume":"386","author":"R\u00f6ssler","year":"2022","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.celrep.2022.111512_bib40","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMc2119236","article-title":"SARS-CoV-2 omicron variant neutralization in serum from vaccinated and convalescent persons","author":"Rossler","year":"2022","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.celrep.2022.111512_bib41","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1126\/science.aba3304","article-title":"An evolution-based model for designing chorismate mutase enzymes","volume":"369","author":"Russ","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.celrep.2022.111512_bib42","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1056\/NEJMc2119641","article-title":"Plasma neutralization of the SARS-CoV-2 omicron variant","volume":"386","author":"Schmidt","year":"2022","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.celrep.2022.111512_bib43","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1038\/s41586-019-1923-7","article-title":"Improved protein structure prediction using potentials from deep learning","volume":"577","author":"Senior","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.111512_bib44","article-title":"Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants","author":"Servellita","year":"2022","journal-title":"medRxiv"},{"key":"10.1016\/j.celrep.2022.111512_bib45","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.cell.2020.08.012","article-title":"Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding","volume":"182","author":"Starr","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2022.111512_bib46","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1038\/s41586-022-04464-z","article-title":"ACE2 binding is an ancestral and evolvable trait of sarbecoviruses","volume":"603","author":"Starr","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2022.111512_bib47","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1186\/s12859-019-3019-7","article-title":"HH-suite3 for fast remote homology detection and deep protein annotation","volume":"20","author":"Steinegger","year":"2019","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.celrep.2022.111512_bib48","doi-asserted-by":"crossref","first-page":"e39397","DOI":"10.7554\/eLife.39397","article-title":"Learning protein constitutive motifs from sequence data","volume":"8","author":"Tubiana","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.celrep.2022.111512_bib49","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/s41592-022-01490-7","article-title":"ScanNet: an interpretable geometric deep learning model for structure-based protein binding site prediction","volume":"19","author":"Tubiana","year":"2022","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2022.111512_bib50","doi-asserted-by":"crossref","first-page":"e1005324","DOI":"10.1371\/journal.pcbi.1005324","article-title":"Accurate de novo prediction of protein contact map by ultra-deep learning model","volume":"13","author":"Wang","year":"2017","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.celrep.2022.111512_bib51","series-title":"Functional Genomics","first-page":"39","article-title":"Protein structure modeling with MODELLER","author":"Webb","year":"2017"},{"key":"10.1016\/j.celrep.2022.111512_bib52","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1038\/s41467-017-01706-x","article-title":"Receptor-binding loops in alphacoronavirus adaptation and evolution","volume":"8","author":"Wong","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2022.111512_bib53","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.cbpa.2021.04.004","article-title":"Protein sequence design with deep generative models","volume":"65","author":"Wu","year":"2021","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.celrep.2022.111512_bib58","doi-asserted-by":"crossref","first-page":"111004","DOI":"10.1016\/j.celrep.2022.111004","article-title":"Superimmunity by pan-sarbecovirus nanobodies","volume":"39","author":"Xiang","year":"2022","journal-title":"Cell Reports"},{"key":"10.1016\/j.celrep.2022.111512_bib54","article-title":"Super-immunity by broadly protective nanobodies to sarbecoviruses","author":"Xiang","year":"2021","journal-title":"bioRxiv"},{"key":"10.1016\/j.celrep.2022.111512_bib55","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1126\/science.abh1139","article-title":"Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants","volume":"373","author":"Yuan","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.celrep.2022.111512_bib56","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1038\/s41564-021-00954-4","article-title":"SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in\u00a0vitro evolution","volume":"6","author":"Zahradn\u00edk","year":"2021","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.celrep.2022.111512_bib57","series-title":"Allergy Bioinformatics","first-page":"175","article-title":"Antigenicity, immunogenicity, allergenicity","author":"Zhang","year":"2015"}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124722013626?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124722013626?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T11:52:31Z","timestamp":1761911551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124722013626"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":58,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S2211124722013626"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2022.111512","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reduced B cell antigenicity of Omicron lowers host serologic response","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2022.111512","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022","name":"copyright","label":"Copyright"}],"article-number":"111512"}}