{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T12:10:55Z","timestamp":1785931855840,"version":"3.56.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T00:00:00Z","timestamp":1679356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["11\/PI\/1056"],"award-info":[{"award-number":["11\/PI\/1056"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["16\/IA\/4468"],"award-info":[{"award-number":["16\/IA\/4468"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["15\/IA\/3041"],"award-info":[{"award-number":["15\/IA\/3041"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["15\/SPP\/3212"],"award-info":[{"award-number":["15\/SPP\/3212"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["16\/IA\/4376"],"award-info":[{"award-number":["16\/IA\/4376"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["202846\/Z\/16\/Z"],"award-info":[{"award-number":["202846\/Z\/16\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"MRC","doi-asserted-by":"publisher","award":["MR\/V032496\/1"],"award-info":[{"award-number":["MR\/V032496\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/T001976\/1"],"award-info":[{"award-number":["BB\/T001976\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.celrep.2023.112341","type":"journal-article","created":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T19:24:03Z","timestamp":1680722643000},"page":"112341","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K.\u00a0pneumoniae infection"],"prefix":"10.1016","volume":"42","author":[{"given":"Marcin","family":"Baran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Feriotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aoife","family":"McGinley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon R.","family":"Carlile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaozhao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Calderon-Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Dumigan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"S\u00e1-Pessoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline E.","family":"Sutton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Kearney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel M.","family":"McLoughlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kingston H.G.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"Fitzgerald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose A.","family":"Bengeochea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew G.","family":"Bowie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2023.112341_bib1","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.it.2011.08.004","article-title":"Cytosolic DNA sensors regulating type I interferon induction","volume":"32","author":"Keating","year":"2011","journal-title":"Trends Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib2","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/1471-2148-12-140","article-title":"The mammalian PYHIN gene family: phylogeny, evolution and expression","volume":"12","author":"Cridland","year":"2012","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.celrep.2023.112341_bib3","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1084\/jem.20121960","article-title":"Extensive evolutionary and functional diversity among mammalian AIM2-like receptors","volume":"209","author":"Brunette","year":"2012","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.celrep.2023.112341_bib4","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1089\/jir.2009.0096","article-title":"Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity","volume":"30","author":"Choubey","year":"2010","journal-title":"J.\u00a0Interferon. Cytokine Res."},{"key":"10.1016\/j.celrep.2023.112341_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.yexcr.2005.03.032","article-title":"The HIN-200 family: more than interferon-inducible genes?","volume":"308","author":"Ludlow","year":"2005","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.celrep.2023.112341_bib6","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1038\/ni.1932","article-title":"IFI16 is an innate immune sensor for intracellular DNA","volume":"11","author":"Unterholzner","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib7","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/nature07725","article-title":"AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC","volume":"458","author":"Hornung","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2023.112341_bib8","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.chom.2011.04.008","article-title":"IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection","volume":"9","author":"Kerur","year":"2011","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2023.112341_bib9","doi-asserted-by":"crossref","first-page":"e1002498","DOI":"10.1371\/journal.ppat.1002498","article-title":"The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication","volume":"8","author":"Gariano","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2023.112341_bib10","doi-asserted-by":"crossref","first-page":"7506","DOI":"10.1128\/JVI.00013-15","article-title":"The nuclear DNA sensor IFI16 acts as a restriction factor for human papillomavirus replication through epigenetic modifications of the viral promoters","volume":"89","author":"Lo Cigno","year":"2015","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.celrep.2023.112341_bib11","doi-asserted-by":"crossref","first-page":"e1004503","DOI":"10.1371\/journal.ppat.1004503","article-title":"IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications","volume":"10","author":"Johnson","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2023.112341_bib12","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.chom.2019.05.002","article-title":"IFI16 targets the transcription factor Sp1 to suppress HIV-1 transcription and latency reactivation","volume":"25","author":"Hotter","year":"2019","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2023.112341_bib13","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1002\/jcb.21512","article-title":"Cloning and characterisation of Ifi206: a new murine HIN-200 family member","volume":"103","author":"Ludlow","year":"2008","journal-title":"J.\u00a0Cell. Biochem."},{"key":"10.1016\/j.celrep.2023.112341_bib14","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.4049\/jimmunol.1700823","article-title":"The PYHIN protein p205 regulates the inflammasome by controlling Asc expression","volume":"199","author":"Ghosh","year":"2017","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib15","doi-asserted-by":"crossref","first-page":"33515","DOI":"10.1074\/jbc.M701846200","article-title":"A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells","volume":"282","author":"Caposio","year":"2007","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2023.112341_bib16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s41467-021-27701-x","article-title":"Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7","volume":"13","author":"Gu","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2023.112341_bib17","doi-asserted-by":"crossref","first-page":"4438","DOI":"10.1074\/jbc.RA119.011400","article-title":"PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells","volume":"295","author":"Massa","year":"2020","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2023.112341_bib18","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s10875-013-9881-6","article-title":"AIM2 facilitates the apoptotic DNA-induced systemic lupus erythematosus via arbitrating macrophage functional maturation","volume":"33","author":"Zhang","year":"2013","journal-title":"J.\u00a0Clin. Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib19","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1177\/0961203309106699","article-title":"Expression profile of HIN200 in leukocytes and renal biopsy of SLE patients by real-time RT-PCR","volume":"18","author":"Kimkong","year":"2009","journal-title":"Lupus"},{"key":"10.1016\/j.celrep.2023.112341_bib20","doi-asserted-by":"crossref","first-page":"25381","DOI":"10.1038\/srep25381","article-title":"Up-regulation of Interferon-inducible protein 16 contributes to psoriasis by modulating chemokine production in keratinocytes","volume":"6","author":"Cao","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2023.112341_bib21","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/acr.22695","article-title":"Circulating interferon-inducible protein IFI16 correlates with clinical and serological features in rheumatoid arthritis","volume":"68","author":"Alunno","year":"2016","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.celrep.2023.112341_bib22","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1097\/MIB.0000000000000535","article-title":"Strong upregulation of AIM2 and IFI16 inflammasomes in the mucosa of patients with active inflammatory bowel disease","volume":"21","author":"Vanhove","year":"2015","journal-title":"Inflamm. Bowel Dis."},{"key":"10.1016\/j.celrep.2023.112341_bib23","doi-asserted-by":"crossref","first-page":"e20201796","DOI":"10.1084\/jem.20201796","article-title":"AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis","volume":"218","author":"Ma","year":"2021","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.celrep.2023.112341_bib24","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/s41586-021-03231-w","article-title":"AIM2 in regulatory T\u00a0cells restrains autoimmune diseases","volume":"591","author":"Chou","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2023.112341_bib25","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ebiom.2018.02.012","article-title":"p204 is required for canonical lipopolysaccharide-induced TLR4 signaling in mice","volume":"29","author":"Yi","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.celrep.2023.112341_bib26","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.1093\/nar\/gkab076","article-title":"Structural mechanism of DNA recognition by the p204 HIN domain","volume":"49","author":"Fan","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2023.112341_bib27","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.immuni.2012.02.014","article-title":"Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor","volume":"36","author":"Jin","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2023.112341_bib28","doi-asserted-by":"crossref","first-page":"e01428-19","DOI":"10.1128\/mBio.01428-19","article-title":"Charge-mediated pyrin oligomerization nucleates antiviral IFI16 sensing of herpesvirus DNA","volume":"10","author":"Lum","year":"2019","journal-title":"mBio"},{"key":"10.1016\/j.celrep.2023.112341_bib29","doi-asserted-by":"crossref","first-page":"11657","DOI":"10.1073\/pnas.92.25.11657","article-title":"Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes","volume":"92","author":"Au","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.112341_bib30","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/nrm3098","article-title":"Unravelling the means to an end: RNA polymerase II transcription termination","volume":"12","author":"Kuehner","year":"2011","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.celrep.2023.112341_bib31","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/gene.2011.21","article-title":"IRF7: activation, regulation, modification and function","volume":"12","author":"Ning","year":"2011","journal-title":"Genes Immun."},{"key":"10.1016\/j.celrep.2023.112341_bib32","doi-asserted-by":"crossref","first-page":"E3574","DOI":"10.1073\/pnas.1501049112","article-title":"Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health","volume":"112","author":"Holt","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.112341_bib33","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1741-7007-12-41","article-title":"Comparative analysis of Klebsiella pneumoniae genomes identifies a phospholipase D family protein as a novel virulence factor","volume":"12","author":"Lery","year":"2014","journal-title":"BMC Biol."},{"key":"10.1016\/j.celrep.2023.112341_bib34","doi-asserted-by":"crossref","first-page":"e16888","DOI":"10.15252\/emmm.202216888","article-title":"In\u00a0vivo single-cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection","volume":"14","author":"Dumigan","year":"2022","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.celrep.2023.112341_bib35","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1111\/cmi.12466","article-title":"Klebsiella pneumoniae survives within macrophages by avoiding delivery to lysosomes","volume":"17","author":"Cano","year":"2015","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.celrep.2023.112341_bib36","doi-asserted-by":"crossref","first-page":"3598","DOI":"10.1038\/sj.onc.1203697","article-title":"The retinoblastoma protein is an essential mediator that links the interferon-inducible 204 gene to cell-cycle regulation","volume":"19","author":"Hertel","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2023.112341_bib37","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.str.2010.12.015","article-title":"Interferon-inducible protein 16: insight into the interaction with tumor suppressor p53","volume":"19","author":"Liao","year":"2011","journal-title":"Structure"},{"key":"10.1016\/j.celrep.2023.112341_bib38","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/nature01889","article-title":"Identification of Lps2 as a key transducer of MyD88-independent TIR signalling","volume":"424","author":"Hoebe","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2023.112341_bib39","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1038\/nsmb.1913","article-title":"Gene-specific RNA polymerase II phosphorylation and the CTD code","volume":"17","author":"Kim","year":"2010","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.celrep.2023.112341_bib40","doi-asserted-by":"crossref","first-page":"e1008752","DOI":"10.1371\/journal.ppat.1008752","article-title":"Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T\u00a0cells","volume":"16","author":"Bosso","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.celrep.2023.112341_bib41","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/(SICI)1097-4644(19980915)70:4<489::AID-JCB6>3.0.CO;2-F","article-title":"Human hematopoietic cell specific nuclear protein MNDA interacts with the multifunctional transcription factor YY1 and stimulates YY1 DNA binding","volume":"70","author":"Xie","year":"1998","journal-title":"J.\u00a0Cell. Biochem."},{"key":"10.1016\/j.celrep.2023.112341_bib42","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.immuni.2020.01.002","article-title":"Interleukin-17A serves a priming role in autoimmunity by recruiting IL-1beta-producing myeloid cells that promote pathogenic T\u00a0cells","volume":"52","author":"McGinley","year":"2020","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2023.112341_bib43","doi-asserted-by":"crossref","first-page":"474","DOI":"10.3389\/fimmu.2019.00474","article-title":"DNA sensor IFI204 contributes to host defense against Staphylococcus aureus infection in mice","volume":"10","author":"Chen","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib44","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1128\/MCB.15.4.2166","article-title":"Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65","volume":"15","author":"Jaffray","year":"1995","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.celrep.2023.112341_bib45","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1128\/iai.57.2.546-552.1989","article-title":"Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor","volume":"57","author":"Nassif","year":"1989","journal-title":"Infect. Immun."},{"key":"10.1016\/j.celrep.2023.112341_bib46","doi-asserted-by":"crossref","first-page":"565545","DOI":"10.3389\/fimmu.2020.565545","article-title":"Manipulation of autophagy and apoptosis facilitates intracellular survival of Staphylococcus aureus in human neutrophils","volume":"11","author":"Mulcahy","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib47","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S1074-7613(00)00053-4","article-title":"Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha\/beta gene induction","volume":"13","author":"Sato","year":"2000","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2023.112341_bib48","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/nature03464","article-title":"IRF-7 is the master regulator of type-I interferon-dependent immune responses","volume":"434","author":"Honda","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2023.112341_bib49","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/416744a","article-title":"RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta","volume":"416","author":"Takayanagi","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2023.112341_bib50","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/ni921","article-title":"IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway","volume":"4","author":"Fitzgerald","year":"2003","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib51","doi-asserted-by":"crossref","first-page":"2986","DOI":"10.1128\/MCB.18.5.2986","article-title":"Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation","volume":"18","author":"Lin","year":"1998","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.celrep.2023.112341_bib52","doi-asserted-by":"crossref","first-page":"34320","DOI":"10.1074\/jbc.M002814200","article-title":"Multiple regulatory domains control IRF-7 activity in response to virus infection","volume":"275","author":"Lin","year":"2000","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2023.112341_bib53","doi-asserted-by":"crossref","first-page":"e00545-17","DOI":"10.1128\/JVI.00545-17","article-title":"Molluscum contagiosum virus protein MC005 inhibits NF-kappaB activation by targeting NEMO-regulated IkappaB kinase activation","volume":"91","author":"Brady","year":"2017","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.celrep.2023.112341_bib54","doi-asserted-by":"crossref","first-page":"16456","DOI":"10.1074\/jbc.M201000200","article-title":"Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling","volume":"277","author":"Radons","year":"2002","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2023.112341_bib55","doi-asserted-by":"crossref","first-page":"4045","DOI":"10.4049\/jimmunol.162.7.4045","article-title":"Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide","volume":"162","author":"Kuprash","year":"1999","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib56","doi-asserted-by":"crossref","first-page":"5358","DOI":"10.4049\/jimmunol.0802736","article-title":"MAIL regulates human monocyte IL-6 production","volume":"183","author":"Seshadri","year":"2009","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib57","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1261\/rna.2192803","article-title":"Lentivirus-delivered stable gene silencing by RNAi in primary cells","volume":"9","author":"Stewart","year":"2003","journal-title":"RNA"},{"key":"10.1016\/j.celrep.2023.112341_bib58","article-title":"The isolation and characterization of murine macrophages","volume":"Chapter 14","author":"Zhang","year":"2008","journal-title":"Curr. Protoc. Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib59","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/ni.1631","article-title":"Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization","volume":"9","author":"Hornung","year":"2008","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.112341_bib60","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1128\/IAI.02254-14","article-title":"The Agr quorum-sensing system regulates fibronectin binding but not hemolysis in the absence of a functional electron transport chain","volume":"82","author":"Pader","year":"2014","journal-title":"Infect. Immun."},{"key":"10.1016\/j.celrep.2023.112341_bib61","doi-asserted-by":"crossref","first-page":"e1006696","DOI":"10.1371\/journal.ppat.1006696","article-title":"Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection","volume":"13","author":"Ivin","year":"2017","journal-title":"PLoS Pathog."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124723003522?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124723003522?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T18:10:11Z","timestamp":1778523011000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124723003522"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["S2211124723003522"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2023.112341","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K.\u00a0pneumoniae infection","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2023.112341","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors.","name":"copyright","label":"Copyright"}],"article-number":"112341"}}