{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:30:34Z","timestamp":1791354634682,"version":"4.3.1"},"reference-count":117,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:00Z","timestamp":1694563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007319","name":"Albert Einstein College of Medicine, Yeshiva University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009670","name":"National Alliance for Research on Schizophrenia and Depression","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009670","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009847","name":"Fordham University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL145302"],"award-info":[{"award-number":["R01HL145302"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01MH123523"],"award-info":[{"award-number":["R01MH123523"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000874","name":"Brain and Behavior Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000874","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.celrep.2023.113187","type":"journal-article","created":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T19:30:27Z","timestamp":1696015827000},"page":"113187","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine"],"prefix":"10.1016","volume":"42","author":[{"given":"Devin","family":"Rocks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Jaric","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Bellia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heining","family":"Cham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Greally","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masako","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6734-4217","authenticated-orcid":false,"given":"Marija","family":"Kundakovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2023.113187_bib1","series-title":"Key Substance Use and Mental Health Indicators in the United States: Results from the 2016 National Survey on Drug Use and Health (HHS Publication No. SMA 17-5044, NSDUH Series H-52)","author":"Administration","year":"2017"},{"key":"10.1016\/j.celrep.2023.113187_bib2","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms13877","article-title":"Dopaminergic dynamics underlying sex-specific cocaine reward","volume":"8","author":"Calipari","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2023.113187_bib3","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/jnr.23963","article-title":"Sex differences, gender and addiction","volume":"95","author":"Becker","year":"2017","journal-title":"J.\u00a0Neurosci. Res."},{"key":"10.1016\/j.celrep.2023.113187_bib4","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/ijnp\/pyx118","article-title":"Estrogen receptor \u03b2 in the nucleus accumbens regulates the rewarding properties of cocaine in female mice","volume":"21","author":"Satta","year":"2018","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.celrep.2023.113187_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2021.108491","article-title":"Sex differences in vulnerability to addiction","volume":"187","author":"Quigley","year":"2021","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib6","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1523\/ENEURO.0278-17.2017","article-title":"Problems and Progress regarding Sex Bias and Omission in Neuroscience Research","volume":"4","author":"Will","year":"2017","journal-title":"eNeuro"},{"key":"10.1016\/j.celrep.2023.113187_bib7","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/j.metabol.2008.07.006","article-title":"Understanding the potency of stressful early life experiences on brain and body function","volume":"57","author":"McEwen","year":"2008","journal-title":"Metabolism"},{"key":"10.1016\/j.celrep.2023.113187_bib8","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s00406-005-0624-4","article-title":"The enduring effects of abuse and related adverse experiences in childhood. A convergence of evidence from neurobiology and epidemiology","volume":"256","author":"Anda","year":"2006","journal-title":"Eur. Arch. Psychiatr. Clin. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2020.100269","article-title":"A novel mouse model for vulnerability to alcohol dependence induced by early-life adversity","volume":"13","author":"Okhuarobo","year":"2020","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.celrep.2023.113187_bib10","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1038\/npp.2016.96","article-title":"Interactions between Early Life Stress, Nucleus Accumbens MeCP2 Expression, and Methamphetamine Self-Administration in Male Rats","volume":"41","author":"Lewis","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.addicn.2023.100067","article-title":"Sex differences in addiction-relevant behavioral outcomes in rodents following early life stress","volume":"6","author":"Rinc\u00f3n-Cort\u00e9s","year":"2023","journal-title":"Addict. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib12","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1080\/10623320600919193","article-title":"Gender specific associations between types of childhood maltreatment and the onset, escalation and severity of substance use in cocaine dependent adults","volume":"32","author":"Hyman","year":"2006","journal-title":"Am. J. Drug Alcohol Abuse"},{"key":"10.1016\/j.celrep.2023.113187_bib13","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1176\/appi.ajp.158.11.1878","article-title":"Childhood abuse and lifetime psychopathology in a community sample","volume":"158","author":"MacMillan","year":"2001","journal-title":"Am. J. Psychiatr."},{"key":"10.1016\/j.celrep.2023.113187_bib14","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0272-7358(00)00088-X","article-title":"Concomitance between childhood sexual and physical abuse and substance use problems. A review","volume":"22","author":"Simpson","year":"2002","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.celrep.2023.113187_bib15","doi-asserted-by":"crossref","first-page":"336","DOI":"10.15288\/jsa.1998.59.336","article-title":"Child sexual and physical abuse and alcoholism: a review","volume":"59","author":"Langeland","year":"1998","journal-title":"J.\u00a0Stud. Alcohol"},{"key":"10.1016\/j.celrep.2023.113187_bib16","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.drugalcdep.2007.08.006","article-title":"Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men","volume":"92","author":"Hyman","year":"2008","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.celrep.2023.113187_bib17","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrn3111","article-title":"Transcriptional and epigenetic mechanisms of addiction","volume":"12","author":"Robison","year":"2011","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib18","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aba4221","article-title":"A dopamine-induced gene expression signature regulates neuronal function and cocaine response","volume":"6","author":"Savell","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.celrep.2023.113187_bib19","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1038\/s41467-019-10704-0","article-title":"Chromatin organization in the female mouse brain fluctuates across the oestrous cycle","volume":"10","author":"Jaric","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2023.113187_bib20","doi-asserted-by":"crossref","first-page":"5098","DOI":"10.1038\/s41467-019-13085-6","article-title":"Early life stress alters transcriptomic patterning across reward circuitry in male and female mice","volume":"10","author":"Pe\u00f1a","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2023.113187_bib21","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2020173118","article-title":"Early life adversity promotes resilience to opioid addiction-related phenotypes in male rats and sex-specific transcriptional changes","volume":"118","author":"Ordo\u00f1es Sanchez","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113187_bib22","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/s41593-021-00814-8","article-title":"Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons","volume":"24","author":"Kronman","year":"2021","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib23","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.biopsych.2010.05.036","article-title":"Epigenetic transmission of the impact of early stress across generations","volume":"68","author":"Franklin","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2023.113187_bib24","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3389\/fnmol.2019.00074","article-title":"Sex and Estrous Cycle Effects on Anxiety- and Depression-Related Phenotypes in a Two-Hit Developmental Stress Model","volume":"12","author":"Jaric","year":"2019","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib25","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3389\/fpsyt.2013.00078","article-title":"Sex-specific and strain-dependent effects of early life adversity on behavioral and epigenetic outcomes","volume":"4","author":"Kundakovic","year":"2013","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.celrep.2023.113187_bib26","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.physbeh.2007.03.014","article-title":"Natural variations in postpartum maternal care in inbred and outbred mice","volume":"91","author":"Champagne","year":"2007","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.celrep.2023.113187_bib27","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0091-3057(02)00859-6","article-title":"Conditioned place preference after single doses or \u201cbinge\u201d cocaine in C57BL\/6J and 129\/J mice","volume":"73","author":"Zhang","year":"2002","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.celrep.2023.113187_bib28","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1038\/npp.2010.67","article-title":"Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin\/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms","volume":"35","author":"Schindler","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib29","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000125310","article-title":"Cocaine disrupts estrous cyclicity and alters the reproductive neuroendocrine axis in the rat","volume":"51","author":"King","year":"1990","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.celrep.2023.113187_bib30","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s13059-018-1536-8","article-title":"Clust: automatic extraction of optimal co-expressed gene clusters from gene expression data","volume":"19","author":"Abu-Jamous","year":"2018","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2023.113187_bib31","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41467-021-27571-3","article-title":"Neuronal Yin Yang1 in the prefrontal cortex regulates transcriptional and behavioral responses to chronic stress in mice","volume":"13","author":"Kwon","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2023.113187_bib32","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1471-2199-10-85","article-title":"YY1 is autoregulated through its own DNA-binding sites","volume":"10","author":"Kim","year":"2009","journal-title":"BMC Mol. Biol."},{"key":"10.1016\/j.celrep.2023.113187_bib33","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1016\/j.celrep.2018.05.040","article-title":"Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses","volume":"23","author":"Besnard","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2023.113187_bib34","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113187_bib35","doi-asserted-by":"crossref","first-page":"3836","DOI":"10.1073\/pnas.96.7.3836","article-title":"Genetic analysis of the mouse X inactivation center defines an 80-kb multifunction domain","volume":"96","author":"Lee","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113187_bib36","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/s13059-015-0733-y","article-title":"Xist localization and function: new insights from multiple levels","volume":"16","author":"Cerase","year":"2015","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2023.113187_bib37","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.cell.2010.09.049","article-title":"The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation","volume":"143","author":"Tian","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2023.113187_bib38","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1093\/hmg\/ddq516","article-title":"Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region","volume":"20","author":"Chureau","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2023.113187_bib39","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/nature19342","article-title":"m(6)A RNA methylation promotes XIST-mediated transcriptional repression","volume":"537","author":"Patil","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2023.113187_bib40","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s13059-015-0618-0","article-title":"The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation","volume":"16","author":"Yang","year":"2015","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2023.113187_bib41","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/nsmb.2532","article-title":"Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway","volume":"20","author":"Nozawa","year":"2013","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.celrep.2023.113187_bib42","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.cell.2018.05.007","article-title":"SMCHD1 Merges Chromosome Compartments and Assists Formation of Super-Structures on the Inactive X","volume":"174","author":"Wang","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2023.113187_bib43","doi-asserted-by":"crossref","first-page":"829","DOI":"10.3389\/fcell.2020.00829","article-title":"PORCN Negatively Regulates AMPAR Function Independently of Subunit Composition and the Amino-Terminal and Carboxy-Terminal Domains of AMPARs","volume":"8","author":"Wei","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.celrep.2023.113187_bib44","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1126\/science.277.5331.1511","article-title":"Binding of neuroligins to PSD-95","volume":"277","author":"Irie","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.celrep.2023.113187_bib45","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0896-6273(00)80157-9","article-title":"SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in\u00a0vivo","volume":"17","author":"M\u00fcller","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2023.113187_bib46","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.neures.2007.10.013","article-title":"IQ-ArfGEF\/BRAG1 is a guanine nucleotide exchange factor for Arf6 that interacts with PSD-95 at postsynaptic density of excitatory synapses","volume":"60","author":"Sakagami","year":"2008","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.celrep.2023.113187_bib47","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.cellsig.2019.03.012","article-title":"Identification of novel PCTAIRE-1\/CDK16 substrates using a chemical genetic screen","volume":"59","author":"Shehata","year":"2019","journal-title":"Cell. Signal."},{"key":"10.1016\/j.celrep.2023.113187_bib48","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.pneurobio.2010.04.006","article-title":"The synapsins: key actors of synapse function and plasticity","volume":"91","author":"Cesca","year":"2010","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.celrep.2023.113187_bib49","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1126\/science.2461586","article-title":"Identification of synaptophysin as a hexameric channel protein of the synaptic vesicle membrane","volume":"242","author":"Thomas","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.celrep.2023.113187_bib50","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/hmg\/ddn321","article-title":"Cognitive impairment in Gdi1-deficient mice is associated with altered synaptic vesicle pools and short-term synaptic plasticity, and can be corrected by appropriate learning training","volume":"18","author":"Bianchi","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2023.113187_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1005079","article-title":"Escape from X inactivation varies in mouse tissues","volume":"11","author":"Berletch","year":"2015","journal-title":"PLoS Genet."},{"key":"10.1016\/j.celrep.2023.113187_bib52","doi-asserted-by":"crossref","first-page":"3438","DOI":"10.1038\/s41467-022-30961-w","article-title":"Sex-specific multi-level 3D genome dynamics in the mouse brain","volume":"13","author":"Rocks","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2023.113187_bib53","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1038\/nmeth.2688","article-title":"Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position","volume":"10","author":"Buenrostro","year":"2013","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2023.113187_bib68","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.biopsych.2022.12.021","article-title":"Cell-type-specific whole-genome landscape of \u0394FOSB binding in nucleus accumbens after chronic cocaine exposure","volume":"94","author":"Yeh","year":"2023","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2023.113187_bib54","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1186\/s12864-022-08637-y","article-title":"Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs","volume":"23","author":"Merrill","year":"2022","journal-title":"BMC Genom."},{"key":"10.1016\/j.celrep.2023.113187_bib55","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.biopsych.2021.02.964","article-title":"Sex-Specific Transcriptional Changes in Response to Adolescent Social Stress in the Brain\u2019s Reward Circuitry","volume":"91","author":"Walker","year":"2022","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2023.113187_bib56","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1038\/s41593-020-00717-0","article-title":"Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble","volume":"23","author":"Marco","year":"2020","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib57","doi-asserted-by":"crossref","first-page":"5965","DOI":"10.1242\/jcs.01589","article-title":"AP-1 subunits: quarrel and harmony among siblings","volume":"117","author":"Hess","year":"2004","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.celrep.2023.113187_bib58","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/s41380-021-01163-5","article-title":"Key transcription factors mediating cocaine-induced plasticity in the nucleus accumbens","volume":"27","author":"Teague","year":"2022","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.celrep.2023.113187_bib59","doi-asserted-by":"crossref","first-page":"3399","DOI":"10.1073\/pnas.0511244103","article-title":"Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens","volume":"103","author":"Lee","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113187_bib60","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1038\/sj.npp.1301456","article-title":"Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene","volume":"33","author":"Covault","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib61","doi-asserted-by":"crossref","first-page":"11042","DOI":"10.1073\/pnas.191352698","article-title":"DeltaFosB: a sustained molecular switch for addiction","volume":"98","author":"Nestler","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113187_bib62","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1038\/nn1143","article-title":"Regulation of gene expression and cocaine reward by CREB and DeltaFosB","volume":"6","author":"McClung","year":"2003","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib63","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.neuron.2009.03.026","article-title":"Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins","volume":"62","author":"Renthal","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2023.113187_bib64","doi-asserted-by":"crossref","first-page":"4295","DOI":"10.1523\/JNEUROSCI.5192-12.2013","article-title":"Behavioral and structural responses to chronic cocaine require a feedforward loop involving \u0394FosB and calcium\/calmodulin-dependent protein kinase II in the nucleus accumbens shell","volume":"33","author":"Robison","year":"2013","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib65","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0325-18.2019","article-title":"Fosb Induction in Nucleus Accumbens by Cocaine Is Regulated by E2F3a","volume":"6","author":"Cates","year":"2019","journal-title":"eNeuro"},{"key":"10.1016\/j.celrep.2023.113187_bib66","doi-asserted-by":"crossref","first-page":"7577","DOI":"10.1523\/JNEUROSCI.1381-12.2012","article-title":"Serum response factor and cAMP response element binding protein are both required for cocaine induction of \u0394FosB","volume":"32","author":"Vialou","year":"2012","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib67","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1038\/nn.3808","article-title":"Genome-wide identification and characterization of functional neuronal activity-dependent enhancers","volume":"17","author":"Malik","year":"2014","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib69","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/ADM.0000000000000515","article-title":"Genetic Variant in the CRH-binding Protein Gene (CRHBP) is Associated With Cessation of Cocaine Use in Methadone Maintenance Patients With Opioid Addiction","volume":"13","author":"Peles","year":"2019","journal-title":"J.\u00a0Addiction Med."},{"key":"10.1016\/j.celrep.2023.113187_bib70","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2021.786855","article-title":"Corticotropin Releasing Factor Binding Protein as a Novel Target to Restore Brain Homeostasis: Lessons Learned From Alcohol Use Disorder Research","volume":"15","author":"Curley","year":"2021","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib71","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.cell.2016.08.067","article-title":"A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors","volume":"167","author":"Li","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2023.113187_bib72","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1038\/sj.npp.1300890","article-title":"Homer isoforms differentially regulate cocaine-induced neuroplasticity","volume":"31","author":"Szumlinski","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib73","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3389\/fnbeh.2018.00271","article-title":"Cocaine-Evoked Locomotor Activity Negatively Correlates With the Expression of Neuromedin U Receptor 2 in the Nucleus Accumbens","volume":"12","author":"Kasper","year":"2018","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib74","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1038\/s41386-021-01234-9","article-title":"Role of neuropeptide neuromedin U in the nucleus accumbens shell in cocaine self-administration in male rats","volume":"47","author":"Kasper","year":"2022","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib75","doi-asserted-by":"crossref","first-page":"dev165456","DOI":"10.1242\/dev.165456","article-title":"SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression","volume":"145","author":"Xu","year":"2018","journal-title":"Development"},{"key":"10.1016\/j.celrep.2023.113187_bib76","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.neulet.2008.09.037","article-title":"Cocaine interacts with the novelty-seeking trait to modulate FGFR1 gene expression in the rat","volume":"446","author":"Turner","year":"2008","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.celrep.2023.113187_bib77","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.pbb.2012.07.006","article-title":"Neonatal fibroblast growth factor treatment enhances cocaine sensitization","volume":"103","author":"Clinton","year":"2012","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.celrep.2023.113187_bib78","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.brainres.2007.04.008","article-title":"Role of glutamate decarboxylase (GAD) isoform, GAD65, in GABA synthesis and transport into synaptic vesicles-Evidence from GAD65-knockout mice studies","volume":"1154","author":"Wu","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.celrep.2023.113187_bib79","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuroimage.2016.02.005","article-title":"Using [(11)C]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism","volume":"132","author":"Lingford-Hughes","year":"2016","journal-title":"Neuroimage"},{"key":"10.1016\/j.celrep.2023.113187_bib80","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.65228","article-title":"Egr2 induction in spiny projection neurons of the ventrolateral striatum contributes to cocaine place preference in mice","volume":"10","author":"Mukherjee","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.celrep.2023.113187_bib81","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqaa083","article-title":"Nuclear Receptor Coactivators (NCOAs) and Corepressors (NCORs) in the Brain","volume":"161","author":"Sun","year":"2020","journal-title":"Endocrinology"},{"key":"10.1016\/j.celrep.2023.113187_bib82","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.neuropharm.2013.08.036","article-title":"AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin","volume":"77","author":"Selvakumar","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib83","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1111\/j.1530-0277.2008.00790.x","article-title":"Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence","volume":"32","author":"Wetherill","year":"2008","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.celrep.2023.113187_bib84","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/s41386-018-0125-6","article-title":"Sex differences in neural mechanisms mediating reward and addiction","volume":"44","author":"Becker","year":"2019","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.yfrne.2022.101010","article-title":"Sex hormone fluctuation and increased female risk for depression and anxiety disorders: From clinical evidence to molecular mechanisms","volume":"66","author":"Kundakovic","year":"2022","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.celrep.2023.113187_bib86","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.pbb.2007.12.013","article-title":"Acute anxiolytic effects of cocaine: the role of test latency and activity phase","volume":"89","author":"M\u00fcller","year":"2008","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.celrep.2023.113187_bib87","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00213-010-1916-6","article-title":"The role of early life stress as a predictor for alcohol and drug dependence","volume":"214","author":"Enoch","year":"2011","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.celrep.2023.113187_bib88","doi-asserted-by":"crossref","first-page":"10397","DOI":"10.1073\/pnas.94.19.10397","article-title":"FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects","volume":"94","author":"Hiroi","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113187_bib89","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/45790","article-title":"Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine","volume":"401","author":"Kelz","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2023.113187_bib90","doi-asserted-by":"crossref","first-page":"2488","DOI":"10.1523\/JNEUROSCI.23-06-02488.2003","article-title":"Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine","volume":"23","author":"Colby","year":"2003","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib91","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0006-8993(03)02230-3","article-title":"Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine","volume":"970","author":"Peakman","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.celrep.2023.113187_bib92","doi-asserted-by":"crossref","DOI":"10.1016\/j.yhbeh.2023.105312","article-title":"Estradiol withdrawal following a hormone simulated pregnancy induces deficits in affective behaviors and increases \u0394FosB in D1 and D2 neurons in the nucleus accumbens core in mice","volume":"149","author":"Foster","year":"2023","journal-title":"Horm. Behav."},{"key":"10.1016\/j.celrep.2023.113187_bib93","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.neuron.2019.01.016","article-title":"The Molecular Basis of Drug Addiction: Linking Epigenetic to Synaptic and Circuit Mechanisms","volume":"102","author":"Nestler","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2023.113187_bib94","doi-asserted-by":"crossref","DOI":"10.1111\/gbb.12689","article-title":"Do gene expression findings from mouse models of cocaine use recapitulate human cocaine use disorder in reward circuitry?","volume":"20","author":"Huggett","year":"2021","journal-title":"Gene Brain Behav."},{"key":"10.1016\/j.celrep.2023.113187_bib95","doi-asserted-by":"crossref","first-page":"R27","DOI":"10.1093\/hmg\/ddi112","article-title":"X-linked genes and mental functioning","volume":"14","author":"Skuse","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2023.113187_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.yhbeh.2020.104821","article-title":"Sex chromosome complement influences vulnerability to cocaine in mice","volume":"125","author":"Martini","year":"2020","journal-title":"Horm. Behav."},{"key":"10.1016\/j.celrep.2023.113187_bib97","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.bbr.2007.02.013","article-title":"The 39,XO mouse as a model for the neurobiology of Turner syndrome and sex-biased neuropsychiatric disorders","volume":"179","author":"Lynn","year":"2007","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.celrep.2023.113187_bib102","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2023.113187_bib103","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2023.113187_bib105","doi-asserted-by":"crossref","first-page":"W191","DOI":"10.1093\/nar\/gkz369","article-title":"g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)","volume":"47","author":"Raudvere","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2023.113187_bib108","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res."},{"key":"10.1016\/j.celrep.2023.113187_bib109","article-title":"SparK: A Publication-quality NGS Visualization Tool","author":"Kurtenbach","year":"2019","journal-title":"bioRxiv"},{"key":"10.1016\/j.celrep.2023.113187_bib112","series-title":"Aligning Sequence Reads, Clone Sequences and Assembly Contigs with BWA-MEM","author":"Li","year":"2013"},{"key":"10.1016\/j.celrep.2023.113187_bib114","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/1471-2105-11-237","article-title":"ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data","volume":"11","author":"Zhu","year":"2010","journal-title":"BMC Bioinf."},{"key":"10.1016\/j.celrep.2023.113187_bib104","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.molcel.2010.05.004","article-title":"Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities","volume":"38","author":"Heinz","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2023.113187_bib115","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1186\/1471-2164-15-284","article-title":"ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases","volume":"15","author":"Shen","year":"2014","journal-title":"BMC Genom."},{"key":"10.1016\/j.celrep.2023.113187_bib113","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkz114","article-title":"The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads","volume":"47","author":"Liao","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2023.113187_bib98","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.neubiorev.2006.05.003","article-title":"Effects of repeated maternal separation on anxiety- and depression-related phenotypes in different mouse strains","volume":"31","author":"Millstein","year":"2007","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.celrep.2023.113187_bib99","doi-asserted-by":"crossref","first-page":"9956","DOI":"10.1073\/pnas.1214056110","article-title":"Sex-specific epigenetic disruption and behavioral changes following low-dose in utero bisphenol A exposure","volume":"110","author":"Kundakovic","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113187_bib100","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2020.582147","article-title":"Drug-Induced Conditioned Place Preference and Its Practical Use in Substance Use Disorder Research","volume":"14","author":"McKendrick","year":"2020","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.celrep.2023.113187_bib101","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1089\/jcr.2014.0015","article-title":"Cocaine Shifts the Estrus Cycle Out of Phase and Caffeine Restores It","volume":"4","author":"Broderick","year":"2014","journal-title":"J.\u00a0Caffeine Res."},{"key":"10.1016\/j.celrep.2023.113187_bib106","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0013984","article-title":"Enrichment map: a network-based method for gene-set enrichment visualization and interpretation","volume":"5","author":"Merico","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.celrep.2023.113187_bib107","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.1093\/bioinformatics\/btq562","article-title":"GeneMANIA Cytoscape plugin: fast gene function predictions on the desktop","volume":"26","author":"Montojo","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2023.113187_bib110","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.biopsych.2016.03.1048","article-title":"Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue","volume":"81","author":"Kundakovic","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.celrep.2023.113187_bib111","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1080\/15592294.2021.1896983","article-title":"Cell type-specific chromatin accessibility analysis in the mouse and human brain","volume":"17","author":"Rocks","year":"2021","journal-title":"Epigenetics"},{"key":"10.1016\/j.celrep.2023.113187_bib116","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.1093\/bioinformatics\/btr568","article-title":"Sequential Monte Carlo multiple testing","volume":"27","author":"Sandve","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2023.113187_bib117","doi-asserted-by":"crossref","first-page":"R86","DOI":"10.1186\/gb-2010-11-8-r86","article-title":"Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences","volume":"11","author":"Goecks","year":"2010","journal-title":"Genome Biol."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124723011993?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124723011993?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T12:17:18Z","timestamp":1761913038000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124723011993"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":117,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S2211124723011993"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2023.113187","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.04.14.536984","asserted-by":"object"}]},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2023.113187","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"113187"}}