{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:06:15Z","timestamp":1786986375224,"version":"build-2736575974"},"reference-count":60,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T00:00:00Z","timestamp":1695340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["158989968"],"award-info":[{"award-number":["158989968"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["390874280"],"award-info":[{"award-number":["390874280"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["RA3077\/1\u20132"],"award-info":[{"award-number":["RA3077\/1\u20132"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005624","name":"Medizinischen Hochschule Hannover","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005624","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.celrep.2023.113230","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T07:21:54Z","timestamp":1696836114000},"page":"113230","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["ROR\u03b3t+ c-Maf+ V\u03b34+ \u03b3\u03b4 T\u00a0cells are generated in the adult thymus but do not reach the periphery"],"prefix":"10.1016","volume":"42","author":[{"given":"Tao","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"Barros-Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Wencker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine","family":"Smout","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prerna","family":"Gambhir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anika","family":"Janssen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Schimrock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hristo","family":"Georgiev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximena","family":"Le\u00f3n-Lara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siegfried","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Huehn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Immo","family":"Prinz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Krueger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhold","family":"Foerster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Walzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3265-6341","authenticated-orcid":false,"given":"Sarina","family":"Ravens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2023.113230_bib1","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1146\/annurev.iy.11.040193.003225","article-title":"Gamma\/delta cells","volume":"11","author":"Haas","year":"1993","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/imr.12918","article-title":"From thymus to periphery: Molecular basis of effector \u03b3\u03b4-T cell differentiation","volume":"298","author":"Fiala","year":"2020","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.celrep.2023.113230_bib3","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1016\/j.celrep.2017.05.071","article-title":"Strong TCR\u03b3\u03b4 Signaling Prohibits Thymic Development of IL-17A-Secreting \u03b3\u03b4 T Cells","volume":"19","author":"Sumaria","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2023.113230_bib4","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/ni.1717","article-title":"CD27 is a thymic determinant of the balance between interferon-\u03b3- and interleukin 17\u2013producing \u03b3\u03b4 T\u00a0cell subsets","volume":"10","author":"Ribot","year":"2009","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/imr.12905","article-title":"Two functionally distinct subsets of IL-17 producing \u03b3\u03b4 T\u00a0cells","volume":"298","author":"O\u2019Brien","year":"2020","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.celrep.2023.113230_bib6","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.immuni.2012.06.003","article-title":"Development of interleukin-17-producing \u03b3\u03b4 T\u00a0cells is restricted to a functional embryonic wave","volume":"37","author":"Haas","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2023.113230_bib7","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.4049\/jimmunol.181.3.1710","article-title":"SCART Scavenger Receptors Identify a Novel Subset of Adult \u03b3\u03b4 T Cells","volume":"181","author":"Kisielow","year":"2008","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib8","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1016\/j.celrep.2019.05.064","article-title":"Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ V\u03b36+ T Cells to Skin Residency as Activated Effector Cells","volume":"27","author":"Tan","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2023.113230_bib9","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.immuni.2018.09.010","article-title":"Interleukin-17-Producing \u03b3\u03b4 T Cells Originate from SOX13+ Progenitors that Are Independent of \u03b3\u03b4TCR Signaling","volume":"49","author":"Spidale","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2023.113230_bib10","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/s41590-018-0094-2","article-title":"\u03b3\u03b4 T\u00a0cells producing interleukin-17A regulate adipose regulatory T\u00a0cell homeostasis and thermogenesis","volume":"19","author":"Kohlgruber","year":"2018","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib11","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1038\/s41385-020-0305-7","article-title":"\u03b3\u03b4 T\u00a0cells compose a developmentally regulated intrauterine population and protect against vaginal candidiasis","volume":"13","author":"Monin","year":"2020","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib12","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20211431","article-title":"PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A-producing \u03b3\u03b4 T\u00a0cells","volume":"220","author":"Edwards","year":"2023","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.celrep.2023.113230_bib13","doi-asserted-by":"crossref","first-page":"6477","DOI":"10.1038\/ncomms7477","article-title":"A clonotypic V\u03b34J\u03b31\/V\u03b45D\u03b42J\u03b41 innate \u03b3\u03b4 T-cell population restricted to the CCR6+CD27\u2212 subset","volume":"6","author":"Kashani","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2023.113230_bib14","doi-asserted-by":"crossref","first-page":"8046","DOI":"10.1073\/pnas.1508990112","article-title":"Inflammation induces dermal V\u03b34\u00a0+ \u03b3\u03b4T17 memory-like cells that travel to distant skin and accelerate secondary IL-17\u2013driven responses","volume":"112","author":"Ram\u00edrez-Valle","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113230_bib15","doi-asserted-by":"crossref","first-page":"e104159","DOI":"10.15252\/embj.2019104159","article-title":"Deciphering the regulatory landscape of fetal and adult \u03b3\u03b4 T-cell development at single-cell resolution","volume":"39","author":"Sagar","year":"2020","journal-title":"EMBO J."},{"key":"10.1016\/j.celrep.2023.113230_bib16","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/s41590-018-0274-0","article-title":"The transcription factor c-Maf is essential for the commitment of IL-17-producing \u03b3\u03b4 T\u00a0cells","volume":"20","author":"Zuberbuehler","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib17","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.immuni.2013.01.010","article-title":"A Network of High-Mobility Group Box Transcription Factors Programs Innate Interleukin-17 Production","volume":"38","author":"Malhotra","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2023.113230_bib18","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.scib.2021.11.013","article-title":"Single-cell RNA-seq and chromatin accessibility profiling decipher the heterogeneity of mouse \u03b3\u03b4 T\u00a0cells","volume":"67","author":"Li","year":"2022","journal-title":"Sci. Bull."},{"key":"10.1016\/j.celrep.2023.113230_bib19","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/ni.2247","article-title":"Intrathymic programming of effector fates in three molecularly distinct \u03b3\u03b4 T\u00a0cell subtypes","volume":"13","author":"Narayan","year":"2012","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib20","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-017-02225-5","article-title":"HEB is required for the specification of fetal IL-17-producing \u03b3\u03b4 T\u00a0cells","volume":"8","author":"In","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2023.113230_bib21","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1182\/blood-2011-02-334995","article-title":"Notch-Hes1 pathway is required for the development of IL-17-producing \u03b3\u03b4 T\u00a0cells","volume":"118","author":"Shibata","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.celrep.2023.113230_bib22","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.4049\/jimmunol.1700287","article-title":"IL-1\u03b2 and IL-23 Promote Extrathymic Commitment of CD27\u00a0+ CD122\u00a0\u2212 \u03b3\u03b4 T Cells to \u03b3\u03b4T17 Cells","volume":"199","author":"Muschaweckh","year":"2017","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib23","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.15252\/embr.201744200","article-title":"IL-23 drives differentiation of peripheral \u03b3\u03b417 T\u00a0cells from adult bone marrow-derived precursors","volume":"18","author":"Papotto","year":"2017","journal-title":"EMBO Rep."},{"key":"10.1016\/j.celrep.2023.113230_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112558","article-title":"A monoclonal Trd chain supports the development of the complete set of functional \u03b3\u03b4 T\u00a0cell lineages","volume":"42","author":"Hahn","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2023.113230_bib25","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/s41423-021-00656-1","article-title":"Single-cell analysis reveals the origins and intrahepatic development of liver-resident IFN-\u03b3-producing \u03b3\u03b4 T\u00a0cells","volume":"18","author":"Hu","year":"2021","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib26","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.4049\/jimmunol.178.5.2730","article-title":"Epigenetic and Transcriptional Programs Lead to Default IFN-\u03b3 Production by \u03b3\u03b4 T Cells","volume":"178","author":"Chen","year":"2007","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib27","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1002\/eji.201646753","article-title":"Eomes expression reports the progressive differentiation of IFN-\u03b3-producing Th1-like \u03b3\u03b4 T\u00a0cells","volume":"47","author":"Lino","year":"2017","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib28","doi-asserted-by":"crossref","first-page":"3642","DOI":"10.4049\/jimmunol.1501921","article-title":"Effector \u03b3\u03b4 T Cell Differentiation Relies on Master but Not Auxiliary Th Cell Transcription Factors","volume":"196","author":"Barros-Martins","year":"2016","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib29","doi-asserted-by":"crossref","first-page":"6091","DOI":"10.4049\/jimmunol.1100427","article-title":"Cutting Edge: Identification of a Motile IL-17\u2013Producing \u03b3\u03b4 T Cell Population in the Dermis","volume":"186","author":"Gray","year":"2011","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib30","doi-asserted-by":"crossref","first-page":"6518","DOI":"10.4049\/jimmunol.1002766","article-title":"Unexpected Role for the B Cell-Specific Src Family Kinase B Lymphoid Kinase in the Development of IL-17\u2013Producing \u03b3\u03b4 T Cells","volume":"185","author":"Laird","year":"2010","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib31","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/ni.2585","article-title":"Deficiency in IL-17-committed V\u03b34+ \u03b3\u03b4 T\u00a0cells in a spontaneous Sox13-mutant CD45.1+ congenic mouse substrain provides protection from dermatitis","volume":"14","author":"Gray","year":"2013","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib32","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.it.2019.03.001","article-title":"ZEBs: Novel Players in Immune Cell Development and Function","volume":"40","author":"Scott","year":"2019","journal-title":"Trends Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib33","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.cell.2012.09.016","article-title":"A Validated Regulatory Network for Th17 Cell Specification","volume":"151","author":"Ciofani","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2023.113230_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109227","article-title":"Ontogenic timing, T\u00a0cell receptor signal strength, and Notch signaling direct \u03b3\u03b4 T\u00a0cell functional differentiation in\u00a0vivo","volume":"35","author":"Chen","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2023.113230_bib35","doi-asserted-by":"crossref","first-page":"4960","DOI":"10.1182\/blood-2009-04-218156","article-title":"Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells","volume":"114","author":"D\u00fcber","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.celrep.2023.113230_bib36","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/s41385-020-0330-6","article-title":"Microbiota-dependent expansion of testicular IL-17-producing V\u03b36+ \u03b3\u03b4 T\u00a0cells upon puberty promotes local tissue immune surveillance","volume":"14","author":"Wilharm","year":"2021","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib37","doi-asserted-by":"crossref","first-page":"8502","DOI":"10.1073\/pnas.1600713113","article-title":"IL-17A\u2013producing resident memory \u03b3\u03b4 T\u00a0cells orchestrate the innate immune response to secondary oral Listeria monocytogenes infection","volume":"113","author":"Romagnoli","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113230_bib38","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/ni1022","article-title":"An essential function for the nuclear receptor ROR\u03b3t in the generation of fetal lymphoid tissue inducer cells","volume":"5","author":"Eberl","year":"2004","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib39","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1084\/jem.20072713","article-title":"Lymphoid tissue inducer\u2013like cells are an innate source of IL-17 and IL-22","volume":"206","author":"Takatori","year":"2009","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.celrep.2023.113230_bib40","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.immuni.2018.07.011","article-title":"Lung \u03b3\u03b4 T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity","volume":"49","author":"Guo","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2023.113230_bib41","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20221534","article-title":"The cIAP ubiquitin ligases sustain type 3 \u03b3\u03b4 T\u00a0cells and ILC during aging to promote barrier immunity","volume":"220","author":"Rizk","year":"2023","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.celrep.2023.113230_bib42","doi-asserted-by":"crossref","first-page":"2994","DOI":"10.1084\/jem.20181206","article-title":"Epidermal \u03b3\u03b4 T\u00a0cells originate from yolk sac hematopoiesis and clonally self-renew in the adult","volume":"215","author":"Gentek","year":"2018","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.celrep.2023.113230_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.108716","article-title":"The E protein-TCF1 axis controls \u03b3\u03b4 T\u00a0cell development and effector fate","volume":"34","author":"Fahl","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2023.113230_bib44","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.4049\/jimmunol.1701053","article-title":"Long-Lived Innate IL-17\u2013Producing \u03b3\/\u03b4 T Cells Modulate Antimicrobial Epithelial Host Defense in the Colon","volume":"199","author":"Muzaki","year":"2017","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib45","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1016\/j.molimm.2010.03.002","article-title":"Elevated numbers of SCART1+ \u03b3\u03b4 T\u00a0cells in skin inflammation and inflammatory bowel disease","volume":"47","author":"Fink","year":"2010","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib46","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.immuni.2012.06.011","article-title":"\u03b3\u03b4 T Cells Recognize a Microbial Encoded B Cell Antigen to Initiate a Rapid Antigen-Specific Interleukin-17 Response","volume":"37","author":"Zeng","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2023.113230_bib47","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1038\/s41423-020-0459-y","article-title":"Zeb1 represses TCR signaling, promotes the proliferation of T\u00a0cell progenitors and is essential for NK1.1+ T\u00a0cell development","volume":"18","author":"Zhang","year":"2021","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib48","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/ni1371","article-title":"Visualization of the earliest steps of \u03b3\u03b4 T\u00a0cell development in the adult thymus","volume":"7","author":"Prinz","year":"2006","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib49","doi-asserted-by":"crossref","first-page":"12286","DOI":"10.1073\/pnas.1209134109","article-title":"A forward genetic screen reveals roles for Nfkbid , Zeb1 , and Ruvbl2 in humoral immunity","volume":"109","author":"Arnold","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113230_bib60","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.2006716","article-title":"miR-181a\/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity","volume":"17","author":"\u0141yszkiewicz","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.celrep.2023.113230_bib59","article-title":"Dictionary learning for integrative, multimodal and scalable single-cell analysis","author":"Hao","year":"2023","journal-title":"Nat. Biotechnol"},{"key":"10.1016\/j.celrep.2023.113230_bib55","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/s41592-021-01282-5","article-title":"Single-cell chromatin state analysis with Signac","volume":"18","author":"Stuart","year":"2021","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2023.113230_bib54","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with Harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2023.113230_bib57","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1038\/s41586-019-0969-x","article-title":"The single-cell transcriptional landscape of mammalian organogenesis","volume":"566","author":"Cao","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2023.113230_bib58","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.molcel.2018.06.044","article-title":"Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data","volume":"71","author":"Pliner","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2023.113230_bib50","doi-asserted-by":"crossref","first-page":"6355","DOI":"10.4049\/jimmunol.163.12.6355","article-title":"Cutting edge: absence of expression of RAG1 in peritoneal B-1 cells detected by knocking into RAG1 locus with green fluorescent protein gene","volume":"163","author":"Kuwata","year":"1999","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2023.113230_bib51","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1073\/pnas.0811556106","article-title":"Heterogeneity of natural Foxp3\u00a0+ T\u00a0cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity","volume":"106","author":"Komatsu","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2023.113230_bib52","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1189\/jlb.0703326","article-title":"Subset-specific, uniform activation among V\u03b36\/V\u03b41\u00a0+ \u03b3\u03b4 T\u00a0cells elicited by inflammation","volume":"75","author":"Roark","year":"2004","journal-title":"J.\u00a0Leukoc. Biol."},{"key":"10.1016\/j.celrep.2023.113230_bib53","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nbt.4096","article-title":"Integrating single-cell transcriptomic data across different conditions, technologies, and species","volume":"36","author":"Butler","year":"2018","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.celrep.2023.113230_bib56","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/nmeth.4401","article-title":"chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data","volume":"14","author":"Schep","year":"2017","journal-title":"Nat. Methods"}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124723012421?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124723012421?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T12:24:20Z","timestamp":1761913460000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124723012421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":60,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S2211124723012421"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2023.113230","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ROR\u03b3t+ c-Maf+ V\u03b34+ \u03b3\u03b4 T\u00a0cells are generated in the adult thymus but do not reach the periphery","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2023.113230","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"113230"}}